ATE466108T1 - Optoelektronisches detektionssystem - Google Patents

Optoelektronisches detektionssystem

Info

Publication number
ATE466108T1
ATE466108T1 AT05858641T AT05858641T ATE466108T1 AT E466108 T1 ATE466108 T1 AT E466108T1 AT 05858641 T AT05858641 T AT 05858641T AT 05858641 T AT05858641 T AT 05858641T AT E466108 T1 ATE466108 T1 AT E466108T1
Authority
AT
Austria
Prior art keywords
detection
target particle
detection system
sample
detecting
Prior art date
Application number
AT05858641T
Other languages
English (en)
Inventor
Eric Schwoebel
James Harper
Martha Petrovick
Frances Nargi
Todd Rider
Kristine Hogan
Richard Mathews
Joseph Lacirignola
Mark Hennessy
Trina Vian
Rose Joseph
Raymond Uttaro
Shaun Berry
Mark Hollis
Bernadette Johnson
Original Assignee
Massachusetts Inst Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Inst Technology filed Critical Massachusetts Inst Technology
Application granted granted Critical
Publication of ATE466108T1 publication Critical patent/ATE466108T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5302—Apparatus specially adapted for immunological test procedures
    • G01N33/5304—Reaction vessels, e.g. agglutination plates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/34—Measuring or testing with condition measuring or sensing means, e.g. colony counters
    • C12M1/3446—Photometry, spectroscopy, laser technology
    • C12M1/3461—Bio- or chemi-luminescence
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/34—Measuring or testing with condition measuring or sensing means, e.g. colony counters
    • C12M1/3446—Photometry, spectroscopy, laser technology
    • C12M1/3476—Fluorescence spectroscopy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6825—Nucleic acid detection involving sensors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates
    • G01N21/6454—Individual samples arranged in a regular 2D-array, e.g. multiwell plates using an integrated detector array
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biophysics (AREA)
  • Sustainable Development (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Geophysics And Detection Of Objects (AREA)
  • Radar Systems Or Details Thereof (AREA)
AT05858641T 2004-12-01 2005-11-30 Optoelektronisches detektionssystem ATE466108T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/001,583 US7422860B2 (en) 2001-02-07 2004-12-01 Optoelectronic detection system
PCT/US2005/043343 WO2007046825A2 (en) 2004-12-01 2005-11-30 Optoelectronic detection system

Publications (1)

Publication Number Publication Date
ATE466108T1 true ATE466108T1 (de) 2010-05-15

Family

ID=37903963

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05858641T ATE466108T1 (de) 2004-12-01 2005-11-30 Optoelektronisches detektionssystem

Country Status (9)

Country Link
US (4) US7422860B2 (de)
EP (1) EP1831404B1 (de)
JP (1) JP5523673B2 (de)
CN (1) CN101111605B (de)
AT (1) ATE466108T1 (de)
AU (1) AU2005337484B2 (de)
CA (1) CA2588787A1 (de)
DE (1) DE602005020978D1 (de)
WO (1) WO2007046825A2 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6248542B1 (en) 1997-12-09 2001-06-19 Massachusetts Institute Of Technology Optoelectronic sensor
EP1750129B1 (de) 2001-02-07 2011-04-20 Massachusetts Institute of Technology Optoelektronisches Detektionssystem
US8216797B2 (en) * 2001-02-07 2012-07-10 Massachusetts Institute Of Technology Pathogen detection biosensor
US7422860B2 (en) 2001-02-07 2008-09-09 Massachusetts Institute Of Technology Optoelectronic detection system
AT500427B1 (de) * 2002-05-29 2009-02-15 Anagnostics Bioanalysis Gmbh Vorrichtung zur analyse von bestandteilen einer probe
AT502549B1 (de) * 2005-10-07 2007-06-15 Anagnostics Bioanalysis Gmbh Vorrichtung zur analyse von flüssigen proben
MX2008006945A (es) * 2005-11-30 2008-10-02 Massachusetts Inst Technology Biosensor de deteccion de patogeno.
US20090270269A1 (en) * 2008-04-28 2009-10-29 Ashok Kumar Nano-scale fluoro-biosensors exhibiting a low false alarm rate for rapid detection of biological contaminants
JP5571294B2 (ja) * 2008-05-14 2014-08-13 旭川ポートリー株式会社 培養装置および培養方法
US20110275535A1 (en) 2008-12-16 2011-11-10 Novartis Ag Yeast Display Systems
US8647829B2 (en) 2009-02-20 2014-02-11 General Electric Company Switchable affinity binders
US8955368B2 (en) 2011-09-21 2015-02-17 Massachusetts Institute Of Technology Apparatus and method for aerosol collection and fluid analysis
US9023640B2 (en) * 2011-12-13 2015-05-05 Fundamental Solutions Corporation Device for rapid detection of infectious agents
CN105190310B (zh) 2013-03-11 2018-04-10 托莱多大学 用于体内原位和/或实时靶定分析物的生物感应器装置及其制造与使用方法
JP6161072B2 (ja) * 2013-12-26 2017-07-12 国立研究開発法人産業技術総合研究所 多チャンネル式化学発光計測システム
GB201600315D0 (en) * 2015-08-13 2016-02-24 Gen Electric Heatseal sampling
CN108305912B (zh) * 2017-01-11 2024-03-26 中国科学院上海微系统与信息技术研究所 具有波长选择性的石墨烯仿生光探测器及其制备方法
KR102016131B1 (ko) * 2017-04-17 2019-10-21 (주)레보스케치 원심력을 이용한 디지털 pcr 장치 및 방법
CN111534419A (zh) * 2020-03-23 2020-08-14 湖南大学 呼吸道微生物快速检测系统及方法
US12270747B2 (en) 2021-04-30 2025-04-08 Root Applied Sciences Inc. Device for collecting material from air
CN114544726B (zh) * 2022-02-21 2024-05-03 浙江理工大学 一种丝素蛋白检测用pn型纤维状光电探测器的制备方法
WO2024137514A1 (en) * 2022-12-22 2024-06-27 Synthego Corporation Systems and method for automated oligonucleotide synthesis
US12546701B2 (en) 2023-12-19 2026-02-10 Enquyst Technologies Inc. Multichannel optical switch for in-line spectroscopic compound analysis

Family Cites Families (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3880592A (en) 1973-07-05 1975-04-29 Instrumentation Labor Inc Blood analysis system including a plasma separator
US4493895A (en) * 1981-09-24 1985-01-15 Occidental Chemical Corporation Microbial degradation of obnoxious organic wastes into innocuous materials
US4499052A (en) * 1982-08-30 1985-02-12 Becton, Dickinson And Company Apparatus for distinguishing multiple subpopulations of cells
US4816567A (en) * 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4632761A (en) * 1983-08-15 1986-12-30 W. R. Grace & Co. Centrifugal microconcentrator and methods for its use
US4675287A (en) * 1984-07-26 1987-06-23 Scripps Clinic And Research Foundation Monoclonal antibody directed to human ganglioside GD2
JPH0823558B2 (ja) * 1984-11-27 1996-03-06 オ−ジエニクス リミテツド 検定装置
NZ214563A (en) * 1984-12-31 1991-05-28 Univ Georgia Production of apoaeqorin using recombinant dna
US5422266A (en) * 1984-12-31 1995-06-06 University Of Georgia Research Foundation, Inc. Recombinant DNA vectors capable of expressing apoaequorin
WO1986007463A1 (en) 1985-06-03 1986-12-18 American National Red Cross Microtiter - surface - flocculation assay for antigen or antibody screening
AU596987B2 (en) * 1985-08-30 1990-05-24 Tosoh Corporation Automated immunoassay analyser
US4678607A (en) 1986-07-25 1987-07-07 E. I. Du Pont De Nemours And Company Ethylene copolymers with enhanced fire resistant properties
US4946778A (en) * 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US5698450A (en) * 1986-10-14 1997-12-16 Ringrose; Anthony Method for measuring antigens or antibodies in biological fluids
JPS6435374A (en) 1987-07-31 1989-02-06 Fujirebio Kk Method and apparatus for fully automatic agglutination immune analysis
EP0301583B1 (de) 1987-07-31 1994-04-27 Fujirebio Kabushiki Kaisha Gerät zur automatischen immunologischen Analyse
JP2592623B2 (ja) * 1987-11-18 1997-03-19 チッソ株式会社 アポエクオリンの製造法
JPH01250065A (ja) * 1988-03-30 1989-10-05 Matsushita Electric Ind Co Ltd 有機ニトロ化合物の検知・分析方法
US5017342A (en) 1988-06-01 1991-05-21 Ortho Diagnostic Systems Inc. Device for immunoassay determinations
US5223409A (en) * 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
DE68922971T2 (de) 1988-12-06 1995-10-19 Chisso Corp Mit einem Protein mit spezifischer Bindungsaktivität fusioniertes Aequorin, seine Herstellung, Reinigung und Nachweismethode.
JPH02253162A (ja) 1989-03-27 1990-10-11 Chisso Corp 特異的結合能を有する物質と結合したエクオリンを用いる検出法
EP0392377B1 (de) 1989-04-07 1995-02-15 Abbott Laboratories Verfahren und Vorrichtung zur Trennung von Plasma oder von Serum aus Blut
JPH03153700A (ja) 1989-11-09 1991-07-01 Chisso Corp 物理吸着法により担体に固定化されたエクオリン活性を示す蛋白質
US5292658A (en) * 1989-12-29 1994-03-08 University Of Georgia Research Foundation, Inc. Boyd Graduate Studies Research Center Cloning and expressions of Renilla luciferase
US5846708A (en) * 1991-11-19 1998-12-08 Massachusetts Institiute Of Technology Optical and electrical methods and apparatus for molecule detection
JPH06507078A (ja) 1992-02-10 1994-08-11 バクスター、インターナショナル、インコーポレイテッド ウイルス汚染について血液単位を試験するための方法
JPH06160387A (ja) * 1992-11-20 1994-06-07 Mitsubishi Kasei Corp 抗原・抗体反応の測定方法
US5360728A (en) * 1992-12-01 1994-11-01 Woods Hole Oceanographic Institution (W.H.O.I.) Modified apoaequorin having increased bioluminescent activity
WO1994018565A1 (en) 1993-02-01 1994-08-18 Labsystems Oy Method and means for magnetic particle specific binding assay
US5714666A (en) * 1993-02-09 1998-02-03 Children's Hospital Of Philadelphia Measurement of intracellular calcium using bioluminescent apoaequorin expressed in mammalian cells
US5552064A (en) * 1993-02-26 1996-09-03 Ortho Diagnostic Systems, Inc. Column agglutination assay and device using biphasic centrifugation
US5578269A (en) * 1993-06-11 1996-11-26 Ortho Diagnostic Systems Inc. Automated blood analysis system with an integral centrifuge
EP0720650B1 (de) * 1993-09-20 2004-12-01 Novartis AG Menschliche metabotropische glutamatrezeptor untertype hmglur7 und verwandte dns-verbindungen
EP0746778A1 (de) 1994-02-25 1996-12-11 Massachusetts Institute Of Technology Verfahren und apparat für den nachweis von teilchen und die abbildungdurch diese teilchen
JP3153700B2 (ja) 1994-03-03 2001-04-09 株式会社アイ・エイチ・アイ・エアロスペース ガスタービンエンジンの点火装置
US6143510A (en) 1994-07-29 2000-11-07 Iatron Laboratories Inc. Measuring method using whole blood sample
US5744320A (en) * 1995-06-07 1998-04-28 Promega Corporation Quenching reagents and assays for enzyme-mediated luminescence
CA2181109A1 (en) 1995-07-18 1997-01-19 Nobuko Imajo Polypeptide and process for measuring living body components using the same
US5585266A (en) 1995-10-05 1996-12-17 Plitt; Cheryl A. Immobilized cell bioreactor
US5702884A (en) 1996-03-12 1997-12-30 Johnson & Johnson Clinical Diagnostics, Inc. Whole blood sample preparation for polymerase chain reaction using ammonium chloride and a carboxylic acid or metal carboxylate for selective red blood cell lysis
US5701012A (en) * 1996-03-19 1997-12-23 Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of National Defence Fluorescent biological particle detection system
US6103479A (en) * 1996-05-30 2000-08-15 Cellomics, Inc. Miniaturized cell array methods and apparatus for cell-based screening
ATE332572T1 (de) * 1996-06-19 2006-07-15 Matsushita Electric Industrial Co Ltd Photoelektronisches material, dieses verwendende vorrichtungen und herstellungsverfahren
DE19631855C2 (de) 1996-08-07 1998-10-15 Komanns Aribert Verfahren und Vorrichtung zur Erfassung von Oberflächenantigenen oder Strukturmerkmalen von Zellen, Partikeln oder Makromolekülen
US20030104390A1 (en) 1996-11-11 2003-06-05 Laurent Etienne Use of biosensors to diagnose plant diseases
US5958703A (en) 1996-12-03 1999-09-28 Glaxo Group Limited Use of modified tethers in screening compound libraries
US5932795A (en) * 1997-01-22 1999-08-03 President And Fellows Of Harvard College Methods and apparatus for continuous ambient particulate mass monitoring
US5985214A (en) * 1997-05-16 1999-11-16 Aurora Biosciences Corporation Systems and methods for rapidly identifying useful chemicals in liquid samples
DE19730497C2 (de) 1997-07-16 2000-02-10 Heermann Klaus Hinrich Verfahren zum Waschen, zur Separierung und Konzentrierung von Biomolekülen unter Verwendung eines Magnetstifts
US6248542B1 (en) * 1997-12-09 2001-06-19 Massachusetts Institute Of Technology Optoelectronic sensor
US6087114A (en) * 1997-12-09 2000-07-11 Massachusetts Institute Of Technology Optoelectronic sensor
US6007778A (en) * 1998-03-20 1999-12-28 Wisconsin Alumni Research Foundation Hermetic reaction tube for spectroscopy
US6261848B1 (en) 1998-05-08 2001-07-17 The Johns Hopkins University Miniature immuno-optical rapid analyte sensor platform
ATE232298T1 (de) * 1998-07-06 2003-02-15 Euroscreen Sa Bioluminenztest für agonisten oder antagonisten eines kalzium-gekuppelten-rezeptors
FR2790093A1 (fr) 1999-02-24 2000-08-25 Scibiex Sarl Procede d'analyse immunologique par reaction d'adherence
GR1003489B (el) 1999-11-19 2000-11-30 Μεθοδος προσδιορισμου βιολογικων και χημικων παραγοντων μεσω της μετρησης των μεταβολων των ηλεκτρικων ιδιοτητων ακινητοποιημενων κυτταρων ή συστατικων αυτων (βιοηλεκτρικη μεθοδος αναγνωρισης)
US6818435B2 (en) * 2000-05-15 2004-11-16 Tecan Trading Ag Microfluidics devices and methods for performing cell based assays
US7144729B2 (en) 2000-09-01 2006-12-05 Dfb Pharmaceuticals, Inc. Methods and compositions for tissue regeneration
EP1750129B1 (de) 2001-02-07 2011-04-20 Massachusetts Institute of Technology Optoelektronisches Detektionssystem
US8216797B2 (en) * 2001-02-07 2012-07-10 Massachusetts Institute Of Technology Pathogen detection biosensor
US7422860B2 (en) * 2001-02-07 2008-09-09 Massachusetts Institute Of Technology Optoelectronic detection system
US6672947B2 (en) * 2001-03-13 2004-01-06 Nptest, Llc Method for global die thinning and polishing of flip-chip packaged integrated circuits
CA2445389A1 (en) 2001-04-23 2002-10-31 Massachusetts Institute Of Technology Antimicrobial polymeric surfaces
CN100436574C (zh) 2001-09-06 2008-11-26 基因描绘系统有限公司 复制细胞的快速检测
US20040058327A1 (en) 2002-09-20 2004-03-25 Pan Jeffrey Y Method for using a blank matrix in a continuous format high throughput screening process
CN1323296C (zh) 2004-07-05 2007-06-27 江苏省肿瘤医院 硅烷交联壳聚糖膜基的流动注射化学发光免疫检测池及制备方法
MX2008006945A (es) 2005-11-30 2008-10-02 Massachusetts Inst Technology Biosensor de deteccion de patogeno.

Also Published As

Publication number Publication date
HK1108468A1 (en) 2008-05-09
CN101111605A (zh) 2008-01-23
DE602005020978D1 (de) 2010-06-10
CN101111605B (zh) 2013-04-03
US8835127B2 (en) 2014-09-16
WO2007046825A9 (en) 2007-06-21
CA2588787A1 (en) 2007-04-26
US7422860B2 (en) 2008-09-09
AU2005337484A1 (en) 2007-04-26
US20080166705A1 (en) 2008-07-10
EP1831404B1 (de) 2010-04-28
US9494579B2 (en) 2016-11-15
WO2007046825A2 (en) 2007-04-26
US20100041031A1 (en) 2010-02-18
US20150050723A1 (en) 2015-02-19
AU2005337484B2 (en) 2010-04-29
JP2008522195A (ja) 2008-06-26
EP1831404A2 (de) 2007-09-12
US20120135404A1 (en) 2012-05-31
WO2007046825A3 (en) 2007-07-26
US8067184B2 (en) 2011-11-29
JP5523673B2 (ja) 2014-06-18

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