BRPI0416602A - promotores da apoptose de n-acilsulfonamida - Google Patents

promotores da apoptose de n-acilsulfonamida

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Publication number
BRPI0416602A
BRPI0416602A BRPI0416602-7A BRPI0416602A BRPI0416602A BR PI0416602 A BRPI0416602 A BR PI0416602A BR PI0416602 A BRPI0416602 A BR PI0416602A BR PI0416602 A BRPI0416602 A BR PI0416602A
Authority
BR
Brazil
Prior art keywords
compounds
apoptosis promoters
acylsulfonamide
protein family
acylsulfonamide apoptosis
Prior art date
Application number
BRPI0416602-7A
Other languages
English (en)
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of BRPI0416602A publication Critical patent/BRPI0416602A/pt
Publication of BRPI0416602B1 publication Critical patent/BRPI0416602B1/pt

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    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
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    • C07D277/62—Benzothiazoles
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    • C07D277/70—Sulfur atoms
    • C07D277/74—Sulfur atoms substituted by carbon atoms
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    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
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Abstract

"PROMOTORES DA APOPTOSE DE N-ACILSULFONAMIDA". São divulgados compostos de N-acilsulfonamida que inibem a atividade dos membros da família de proteínas antiapoptóticas, composições contendo os compostos é os usos dos compostos para preparar medicamentos para tratar as doenças durante as quais ocorre a expressão de um ou mais do que um membro da família de proteínas antiapoptótica.
BRPI0416602-7A 2003-11-13 2004-11-12 Compostos promotores da apoptose de nacilsulfonamida, composição farmacêutica que compreende os ditos compostos e uso dos mesmos para tratar câncer BRPI0416602B1 (pt)

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PCT/US2004/037911 WO2005049594A1 (en) 2003-11-13 2004-11-12 N-acylsulfonamide apoptosis promoters

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AU2004290666A1 (en) 2005-06-02
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JP2007511530A (ja) 2007-05-10
WO2005049594A1 (en) 2005-06-02
DK2308812T3 (da) 2014-06-02
DK1685119T3 (en) 2016-06-13
CA2546101C (en) 2013-06-11
IL175609A (en) 2013-03-24
KR20060114704A (ko) 2006-11-07
US20050159427A1 (en) 2005-07-21
BRPI0416602B1 (pt) 2021-10-19
CN1906183B (zh) 2012-06-20
ES2461615T3 (es) 2014-05-20
HUE028622T2 (en) 2016-12-28
TWI337601B (en) 2011-02-21
EP2308812A2 (en) 2011-04-13
WO2005049593A2 (en) 2005-06-02
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EP1685119A1 (en) 2006-08-02
CN1906183A (zh) 2007-01-31
ES2697403T3 (es) 2019-01-23
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US20100022773A1 (en) 2010-01-28
NZ547160A (en) 2009-11-27
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EP3048098A1 (en) 2016-07-27
HK1156295A1 (en) 2012-06-08
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US8084607B2 (en) 2011-12-27
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