BRPI0417810A - arilpirazóis substituìdos como agentes parasiticidas - Google Patents

arilpirazóis substituìdos como agentes parasiticidas

Info

Publication number
BRPI0417810A
BRPI0417810A BRPI0417810-6A BRPI0417810A BRPI0417810A BR PI0417810 A BRPI0417810 A BR PI0417810A BR PI0417810 A BRPI0417810 A BR PI0417810A BR PI0417810 A BRPI0417810 A BR PI0417810A
Authority
BR
Brazil
Prior art keywords
parasiticidal agents
agents
substituted arylpyrazoles
arylpyrazoles
substituted
Prior art date
Application number
BRPI0417810-6A
Other languages
English (en)
Inventor
Denis Billen
Nathan Anthony Logan Chubb
David Morris Gethin
Kim Thomas Hall
Lee Richard Roberts
Nigel Derek Arthur Walshe
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=30471290&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0417810(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer filed Critical Pfizer
Publication of BRPI0417810A publication Critical patent/BRPI0417810A/pt
Publication of BRPI0417810B1 publication Critical patent/BRPI0417810B1/pt
Publication of BRPI0417810B8 publication Critical patent/BRPI0417810B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/28—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
    • A01N47/38—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the group >N—CO—N< where at least one nitrogen atom is part of a heterocyclic ring; Thio analogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms
    • C07D231/40—Acylated on said nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

"ARILPIRAZóIS SUBSTITUìDOS COMO AGENTES PARASITICIDAS". Essa invenção se refere a uma faixa de 1-aril-4-ciclopropil-pirazóis nos quais existe pelo menos um flúor anexado ao anel ciclopropila, às composições compreendendo tais compostos, aos processos para sua síntese e seu uso como parasiticidas.
BRPI0417810A 2003-12-18 2004-12-15 arilpirazóis substituídos como agentes parasiticidas, composição veterinária e uso dos mesmos BRPI0417810B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0329314.9 2003-12-18
GBGB0329314.9A GB0329314D0 (en) 2003-12-18 2003-12-18 Substituted arylpyrazoles
PCT/IB2004/004193 WO2005060749A1 (en) 2003-12-18 2004-12-15 Substituted arylpyrazoles as parasiticidal agents

Publications (3)

Publication Number Publication Date
BRPI0417810A true BRPI0417810A (pt) 2007-04-10
BRPI0417810B1 BRPI0417810B1 (pt) 2018-11-21
BRPI0417810B8 BRPI0417810B8 (pt) 2021-05-25

Family

ID=30471290

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0417810A BRPI0417810B8 (pt) 2003-12-18 2004-12-15 arilpirazóis substituídos como agentes parasiticidas, composição veterinária e uso dos mesmos

Country Status (32)

Country Link
US (1) US7435753B2 (pt)
EP (1) EP1705989B8 (pt)
JP (2) JP4805164B2 (pt)
KR (1) KR100815637B1 (pt)
CN (1) CN100377645C (pt)
AR (1) AR046942A1 (pt)
AT (1) ATE413809T1 (pt)
AU (1) AU2004304717B2 (pt)
BR (1) BRPI0417810B8 (pt)
CA (1) CA2549479C (pt)
CY (1) CY1108649T1 (pt)
DE (1) DE602004017782D1 (pt)
DK (1) DK1705989T3 (pt)
EA (1) EA010740B1 (pt)
ES (1) ES2315724T3 (pt)
GB (1) GB0329314D0 (pt)
IL (1) IL175992A0 (pt)
IS (1) IS8492A (pt)
MA (1) MA28269A1 (pt)
MX (1) MXPA06007006A (pt)
NO (1) NO20062549L (pt)
NZ (1) NZ547565A (pt)
PL (1) PL1705989T3 (pt)
PT (1) PT1705989E (pt)
RS (1) RS51111B (pt)
SI (1) SI1705989T1 (pt)
TN (1) TNSN06187A1 (pt)
TW (1) TW200526605A (pt)
UA (1) UA83397C2 (pt)
UY (1) UY28670A1 (pt)
WO (1) WO2005060749A1 (pt)
ZA (1) ZA200604715B (pt)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7514464B2 (en) * 2003-12-18 2009-04-07 Pfizer Limited Substituted arylpyrazoles
US20080146643A1 (en) * 2005-06-15 2008-06-19 Pfizer Limited Combination
US20070149464A1 (en) * 2005-06-15 2007-06-28 Pfizer Inc. Combination
US20080176865A1 (en) * 2005-06-15 2008-07-24 Pfizer Limited Substituted arylpyrazoles
US7645786B2 (en) 2005-06-15 2010-01-12 Pfizer Inc. Substituted arylpyrazoles
CN101228134A (zh) * 2005-06-15 2008-07-23 辉瑞有限公司 用作杀寄生虫剂的取代芳基吡唑
EP1968578A4 (en) 2005-12-14 2011-02-23 Makhteshim Chem Works Ltd POLYMORPHIC AND AMORPHOUS FORMS OF 5-AMINO-L- [2,6-DICHLORO-4- (TRIFLUOROMETHYL) PHENYL] -4- [(TRIFLUOROMETHYL) SULFINYL] -IH-PYRAZOLE-3-CARBONITRIL
FR2928919B1 (fr) 2008-03-19 2011-07-29 Rhodia Operations Procede de preparation de l'acide difluoroacetique et de ses sels
AU2009281457A1 (en) 2008-08-14 2010-02-18 Bayer Cropscience Ag Insecticidal 4-phenyl-1H-pyrazoles
EP2184273A1 (de) 2008-11-05 2010-05-12 Bayer CropScience AG Halogen-substituierte Verbindungen als Pestizide
BRPI1006408A2 (pt) * 2009-03-16 2016-02-10 Basf Se processo para a preparação de derivados de pirazol de fórmula (i)
EP2253617A1 (de) 2009-05-20 2010-11-24 Bayer CropScience AG Halogen-substituierte Verbindungen als Pestizide
US20110129574A1 (en) * 2009-11-30 2011-06-02 Pathak Chandrashekhar P Methods and compositions for filling fleshy fruits and vegetables
MX2012011549A (es) 2010-04-08 2013-01-29 Ah Usa 42 Llc Derivados de 3,5-difenil-isoxazolina sustituida como insecticidas y acaricidas.
JP2012046486A (ja) * 2010-07-30 2012-03-08 Sumitomo Chemical Co Ltd 動物外部寄生虫防除剤
ES2682303T3 (es) 2010-08-05 2018-09-19 Zoetis Services Llc Derivados de isoxazolina como agentes antiparasitarios
EP2619189B1 (en) 2010-09-24 2020-04-15 Zoetis Services LLC Isoxazoline oximes as antiparasitic agents
FR2972452B1 (fr) 2011-03-09 2013-03-15 Rhodia Operations Procede de preparation du difluoroacetonitrile et de ses derives
PH12013501831B1 (en) 2011-03-10 2019-06-14 Zoetis Services Llc Spirocyclic isoxazoline derivatives as antiparasitic agents
CN103562190A (zh) 2011-03-22 2014-02-05 佐蒂斯有限责任公司 作为抗寄生虫药的异噁唑啉衍生物
WO2013116230A1 (en) 2012-02-03 2013-08-08 Zoetis Llc Dihydrofuran azetidine derivatives as antiparasitic agents
MX336431B (es) 2012-05-09 2016-01-18 Zoetis Services Llc Derivados de azetidina como agentes antiparasitarios.
MX363173B (es) 2012-12-12 2019-03-12 Zoetis Services Llc Composiciones inyectables de fenilpirazol.
DE102023117229A1 (de) 2023-06-29 2025-01-02 Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts Fluorcyclopropylierungsreagens

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2658725A1 (de) 1976-12-24 1978-07-06 Bayer Ag Mittel zur bekaempfung von tierischen ektoparasiten mit stark ausgepraegter residualwirkung
US4479968A (en) 1980-10-17 1984-10-30 The Wellcome Foundation Ltd. Control of ectoparasitic infestations of pigs
US5232940A (en) 1985-12-20 1993-08-03 Hatton Leslie R Derivatives of N-phenylpyrazoles
GB8531485D0 (en) 1985-12-20 1986-02-05 May & Baker Ltd Compositions of matter
GB8713768D0 (en) 1987-06-12 1987-07-15 May & Baker Ltd Compositions of matter
US5547974A (en) 1985-12-20 1996-08-20 Rhone-Poulenc Agriculture Ltd. Derivatives of N-phenylpyrazoles
GB8713769D0 (en) 1987-06-12 1987-07-15 May & Baker Ltd Compositions of matter
GB8613914D0 (en) 1986-06-07 1986-07-09 Coopers Animal Health Liquid formulations
EP0273862B1 (de) 1986-12-05 1991-07-10 Ciba-Geigy Ag Ektoparasitizide nicht-wässrige Pour-on-Flüssigformulierung
DE3706993A1 (de) 1987-03-05 1988-09-15 Bayer Ag 5-amino-3-halogenalkyl-1-aryl-pyrazole
SE455750B (sv) 1987-06-11 1988-08-01 Ericsson Telefon Ab L M Digitalt tidsmultiplext mobiltelefonisystem med ett effektivt utnyttjande av varje tidsram
GB9120641D0 (en) 1991-09-27 1991-11-06 Ici Plc Heterocyclic compounds
ZA94170B (en) 1993-01-20 1995-03-15 Soltec Res Pty Ltd Ectoparasiticidal formulation
AUPM437194A0 (en) 1994-03-11 1994-03-31 Commonwealth Scientific And Industrial Research Organisation Pesticide formulation
JPH08208620A (ja) * 1995-02-03 1996-08-13 Takeda Chem Ind Ltd アミノピラゾール誘導体、その製造法および用途
AU6655196A (en) 1995-08-11 1997-03-12 Novo Nordisk A/S Novel lipolytic enzymes
GB9601128D0 (en) 1995-08-11 1996-03-20 Pfizer Ltd Parasiticidal compounds
JPH0987111A (ja) 1995-09-27 1997-03-31 Sumitomo Chem Co Ltd 害虫駆除用毒餌剤
FR2739255B1 (fr) 1995-09-29 1998-09-04 Rhone Merieux Composition antiparasitaire pour le traitement et la protection des animaux de compagnie
DE69627281T2 (de) 1995-12-19 2003-11-13 Bayer Cropscience S.A., Lyon Neue 1-Aryl Pyrazol Derivate und ihre Verwendung als Schädlingsbekämpfungsmittel
GR1002899B (el) 1996-03-29 1998-05-11 Rhone Merieux Περιλαιμιο κατα ψυλλων και κροτωνων για σκυλους και γατες, με βαση ν-φαινυλπυραζολη
IE970215A1 (en) 1996-03-29 1997-10-08 Rhone Merieux Direct pour-on skin solution for antiparasitic use in cattle¹and sheep
IE80657B1 (en) 1996-03-29 1998-11-04 Merial Sas Insecticidal combination to control mammal fleas in particular fleas on cats and dogs
GR970100096A (el) 1996-03-29 1997-11-28 Merial Εξωτερικη διαταξη κατα των παρασιτων για βοοειδη με βαση τη ν-φαινυλπυραζολη, ειδικα σκουλαρικια.
TW524667B (en) * 1996-12-05 2003-03-21 Pfizer Parasiticidal pyrazoles
GB9801851D0 (en) * 1998-01-29 1998-03-25 Pfizer Ltd Parasiticidal agents
GB9810354D0 (en) * 1998-05-14 1998-07-15 Pfizer Ltd Heterocycles

Also Published As

Publication number Publication date
BRPI0417810B1 (pt) 2018-11-21
CN1893825A (zh) 2007-01-10
ATE413809T1 (de) 2008-11-15
HK1096824A1 (en) 2007-06-15
IL175992A0 (en) 2006-10-05
JP4805164B2 (ja) 2011-11-02
CN100377645C (zh) 2008-04-02
AU2004304717A1 (en) 2005-07-07
IS8492A (is) 2006-05-31
DE602004017782D1 (de) 2008-12-24
WO2005060749A1 (en) 2005-07-07
UA83397C2 (uk) 2008-07-10
EP1705989B8 (en) 2009-03-25
US20050148649A1 (en) 2005-07-07
TNSN06187A1 (fr) 2007-11-15
ZA200604715B (en) 2007-03-28
SI1705989T1 (sl) 2009-02-28
GB0329314D0 (en) 2004-01-21
CA2549479C (en) 2009-08-18
BRPI0417810B8 (pt) 2021-05-25
MXPA06007006A (es) 2006-08-31
JP2007514735A (ja) 2007-06-07
EA200600979A1 (ru) 2006-10-27
MA28269A1 (fr) 2006-11-01
PL1705989T3 (pl) 2009-04-30
CA2549479A1 (en) 2005-07-07
TW200526605A (en) 2005-08-16
JP2008174563A (ja) 2008-07-31
CY1108649T1 (el) 2014-04-09
UY28670A1 (es) 2005-07-29
EP1705989A1 (en) 2006-10-04
PT1705989E (pt) 2009-01-20
NO20062549L (no) 2006-06-27
US7435753B2 (en) 2008-10-14
KR20060101777A (ko) 2006-09-26
ES2315724T3 (es) 2009-04-01
EP1705989B1 (en) 2008-11-12
AR046942A1 (es) 2006-01-04
EA010740B1 (ru) 2008-10-30
KR100815637B1 (ko) 2008-03-20
NZ547565A (en) 2009-07-31
DK1705989T3 (da) 2009-01-19
RS51111B (sr) 2010-10-31
AU2004304717B2 (en) 2010-11-18

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