BRPI0418799A - método para produzir ácido succìnico de hidrolisados de tipo industrial, e, mutante bacteriano - Google Patents

método para produzir ácido succìnico de hidrolisados de tipo industrial, e, mutante bacteriano

Info

Publication number
BRPI0418799A
BRPI0418799A BRPI0418799-7A BRPI0418799A BRPI0418799A BR PI0418799 A BRPI0418799 A BR PI0418799A BR PI0418799 A BRPI0418799 A BR PI0418799A BR PI0418799 A BRPI0418799 A BR PI0418799A
Authority
BR
Brazil
Prior art keywords
succinic acid
bacterial mutant
producing succinic
industrial grade
organism
Prior art date
Application number
BRPI0418799-7A
Other languages
English (en)
Inventor
Nhuan Phu Nghiem
Mark Donnelly
Cynthia Y Sanville-Millard
Original Assignee
Ut Battelle Llc
Univ Chicago
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ut Battelle Llc, Univ Chicago filed Critical Ut Battelle Llc
Publication of BRPI0418799A publication Critical patent/BRPI0418799A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids
    • C12P7/46—Dicarboxylic acids having four or less carbon atoms, e.g. fumaric acid, maleic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

MéTODO PARA PRODUZIR áCIDO SUCCìNICO DE HIDROLISADOS DE TIPO INDUSTRIAL, E, MUTANTE BACTERIANO. Um método para produzir ácido succínico de hidrolisados de tipo industrial utiliza um organismo que contém mutações para os genes ptsG, pflB e ldhA, e permite que o organismo acumule biomassa, e permite que o organismo metabolize o hidrolisado. Um mutante de bactéria produz ácido succínico do substrato contido no hidrolisado de tipo industrial em uma relação entre 0,6:1 e 1,3:1 de ácido succínico para substrato.
BRPI0418799-7A 2004-05-03 2004-05-03 método para produzir ácido succìnico de hidrolisados de tipo industrial, e, mutante bacteriano BRPI0418799A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2004/013605 WO2005116227A1 (en) 2004-05-03 2004-05-03 A method to produce succinic acid from raw hydrolysates

Publications (1)

Publication Number Publication Date
BRPI0418799A true BRPI0418799A (pt) 2007-10-16

Family

ID=35450899

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0418799-7A BRPI0418799A (pt) 2004-05-03 2004-05-03 método para produzir ácido succìnico de hidrolisados de tipo industrial, e, mutante bacteriano

Country Status (17)

Country Link
EP (1) EP1751292B1 (pt)
JP (1) JP4627778B2 (pt)
CN (1) CN101018866A (pt)
AT (1) ATE473286T1 (pt)
AU (1) AU2004320154B2 (pt)
BR (1) BRPI0418799A (pt)
CA (1) CA2565727C (pt)
CY (1) CY1110827T1 (pt)
DE (1) DE602004028054D1 (pt)
DK (1) DK1751292T3 (pt)
ES (1) ES2348513T3 (pt)
HU (1) HUP0600905A2 (pt)
MX (1) MXPA06012770A (pt)
PL (1) PL1751292T3 (pt)
PT (1) PT1751292E (pt)
SI (1) SI1751292T1 (pt)
WO (1) WO2005116227A1 (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2415820A3 (en) * 2006-10-26 2012-10-31 Xyleco, Inc. Method of changing the molecular structure of biomass
WO2008133131A1 (ja) 2007-04-16 2008-11-06 Ajinomoto Co., Inc. 有機酸の製造方法
CN101688176B (zh) 2007-04-17 2013-11-06 味之素株式会社 具有羧基的酸性物质的生产方法
JP2010187542A (ja) * 2007-06-14 2010-09-02 Ajinomoto Co Inc 有機酸の製造方法
WO2009072562A1 (ja) 2007-12-06 2009-06-11 Ajinomoto Co., Inc. 有機酸の製造方法
FR2925068B1 (fr) * 2007-12-13 2010-01-08 Roquette Freres Procedes de production d'acide succinique
EP2396401B1 (en) * 2009-02-16 2018-12-19 Basf Se Novel microbial succinic acid producers and purification of succinic acid
CA2756705C (en) 2009-04-02 2017-04-11 University Of Florida Research Foundation, Inc. Engineered bacterial cells for succinate production
JP5609869B2 (ja) 2009-05-27 2014-10-22 味の素株式会社 有機酸の製造方法
US9605285B2 (en) 2011-01-25 2017-03-28 Cargill, Incorporated Compositions and methods for succinate production
EP2807262A4 (en) 2012-01-25 2015-12-30 Bioamber Internat S A R L PROCESS FOR SUCCINATE MANUFACTURE
US9850507B2 (en) 2012-07-25 2017-12-26 Cargill, Incorporated Yeast cells having reductive TCA pathway from pyruvate to succinate and overexpressing an exogenous NAD(P)+ transhydrogenase enzyme
KR102304834B1 (ko) * 2014-02-07 2021-09-27 바스프 에스이 숙신산 생산을 위한 개선된 미생물
JP2017216881A (ja) 2014-12-26 2017-12-14 味の素株式会社 ジカルボン酸の製造方法
CN112717940B (zh) * 2019-10-28 2023-07-21 中国石油化工股份有限公司 用于制γ-丁内酯的催化剂及其制备方法和应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6743610B2 (en) * 2001-03-30 2004-06-01 The University Of Chicago Method to produce succinic acid from raw hydrolysates

Also Published As

Publication number Publication date
CA2565727C (en) 2012-02-21
AU2004320154B2 (en) 2010-09-02
JP4627778B2 (ja) 2011-02-09
EP1751292B1 (en) 2010-07-07
CN101018866A (zh) 2007-08-15
SI1751292T1 (sl) 2010-12-31
ATE473286T1 (de) 2010-07-15
WO2005116227A1 (en) 2005-12-08
DK1751292T3 (da) 2010-11-01
CA2565727A1 (en) 2005-12-08
EP1751292A4 (en) 2008-09-17
EP1751292A1 (en) 2007-02-14
DE602004028054D1 (de) 2010-08-19
JP2007535926A (ja) 2007-12-13
HUP0600905A2 (en) 2008-05-28
ES2348513T3 (es) 2010-12-07
MXPA06012770A (es) 2007-02-14
CY1110827T1 (el) 2015-06-10
AU2004320154A1 (en) 2005-12-08
PT1751292E (pt) 2010-10-12
PL1751292T3 (pl) 2011-01-31

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O ARTIGO 8O C/C 11 E 25 DA LPI.

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.