BRPI0514734A - variedade bacteriana geneticamente planejada, método para produzir ácidos carboxìlicos em uma cultura anaeróbica e método para produzir ácido succìnico - Google Patents

variedade bacteriana geneticamente planejada, método para produzir ácidos carboxìlicos em uma cultura anaeróbica e método para produzir ácido succìnico

Info

Publication number
BRPI0514734A
BRPI0514734A BRPI0514734-4A BRPI0514734A BRPI0514734A BR PI0514734 A BRPI0514734 A BR PI0514734A BR PI0514734 A BRPI0514734 A BR PI0514734A BR PI0514734 A BRPI0514734 A BR PI0514734A
Authority
BR
Brazil
Prior art keywords
producing
succinic acid
carboxylic acids
genetically engineered
anaerobic culture
Prior art date
Application number
BRPI0514734-4A
Other languages
English (en)
Inventor
Ka-Yiu San
George N Bennett
Ailen Sanchez
Original Assignee
Rice University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rice University filed Critical Rice University
Publication of BRPI0514734A publication Critical patent/BRPI0514734A/pt
Publication of BRPI0514734B1 publication Critical patent/BRPI0514734B1/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids
    • C12P7/46—Dicarboxylic acids having four or less carbon atoms, e.g. fumaric acid, maleic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

VARIEDADE BACTERIANA GENETICAMENTE PLANEJADA, MéTODO PARA PRODUZIR áCIDOS CARBOXìLICOS EM UMA CULTURA ANAERóBICA E MéTODO PARA PRODUZIR áCIDO SUCCìNICO A invenção refere-se a uma variedade mutante de bactérias, que são desprovidas ou que contêm genes mutantes para diversas enzimas metabólicas chave, e que produzem grandes quantidades de ácido succínico sob condições anaeróbicas.
BRPI0514734-4A 2004-08-27 2005-08-29 VARIEDADE BACTERIANA DE E. Coli MODIFICADA BRPI0514734B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US60492204P 2004-08-27 2004-08-27
US60/604,922 2004-08-27
PCT/US2005/030689 WO2006031424A2 (en) 2004-08-27 2005-08-29 Mutant e. coli strain with increased succinic acid production

Publications (2)

Publication Number Publication Date
BRPI0514734A true BRPI0514734A (pt) 2008-06-24
BRPI0514734B1 BRPI0514734B1 (pt) 2018-02-06

Family

ID=36060505

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0514734-4A BRPI0514734B1 (pt) 2004-08-27 2005-08-29 VARIEDADE BACTERIANA DE E. Coli MODIFICADA

Country Status (7)

Country Link
US (2) US7223567B2 (pt)
EP (2) EP1781797B1 (pt)
JP (1) JP4771437B2 (pt)
KR (1) KR101245428B1 (pt)
CN (1) CN101044245B (pt)
BR (1) BRPI0514734B1 (pt)
WO (1) WO2006031424A2 (pt)

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CN101044245A (zh) 2007-09-26
CN101044245B (zh) 2012-05-02
JP2008516585A (ja) 2008-05-22
WO2006031424A3 (en) 2006-11-30
US20060046288A1 (en) 2006-03-02
KR20070053716A (ko) 2007-05-25
EP1781797B1 (en) 2016-10-19
BRPI0514734B1 (pt) 2018-02-06
US7790416B2 (en) 2010-09-07
EP1781797A2 (en) 2007-05-09
US7223567B2 (en) 2007-05-29
EP3130676A1 (en) 2017-02-15
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