BRPI0502691A - composição farmacêutica para o controle da glicose no sangue de pacientes com diabetes tipo 2 - Google Patents

composição farmacêutica para o controle da glicose no sangue de pacientes com diabetes tipo 2

Info

Publication number
BRPI0502691A
BRPI0502691A BRPI0502691-1A BRPI0502691A BRPI0502691A BR PI0502691 A BRPI0502691 A BR PI0502691A BR PI0502691 A BRPI0502691 A BR PI0502691A BR PI0502691 A BRPI0502691 A BR PI0502691A
Authority
BR
Brazil
Prior art keywords
patients
diabetes
type
blood glucose
pharmaceutical composition
Prior art date
Application number
BRPI0502691-1A
Other languages
English (en)
Inventor
Jose Manoel Francisco La Ochoa
Original Assignee
Silanes Sa De Cv Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27607097&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0502691(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Silanes Sa De Cv Lab filed Critical Silanes Sa De Cv Lab
Publication of BRPI0502691A publication Critical patent/BRPI0502691A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

"COMPOSIçãO FARMACEUTICA PARA O CONTROLE DA GLICOSE NO SANGUE DE PACIENTES COM DIABETES TIPO 2". Formada por uma composição farmacêutica das substancias ativas Glimepirida e Metformina ou seus sais como cloridrato, succinato, fumarato, etc. para o controle do glicose no sangue de pacientes com diabetes tipo 2. CARACTERIZADA pela eficiência da combinação provou-se que existe um efeito não apenas aditivo dos dois fármacos mas também sinergético, em comparação com a monoterapia empregando apenas algum dos fármacos da combinação. Em conseqüência, é proposto o Liso da combinação como uma terapia eficaz e segura para controle de glicose no sangue de pacientes com diabetes tipo 2 empregando diversas proporções das substancias ativas nas combinações, para adequar-se às diferentes necessidades dos pacientes.
BRPI0502691-1A 2002-01-25 2005-07-08 composição farmacêutica para o controle da glicose no sangue de pacientes com diabetes tipo 2 BRPI0502691A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
MXPA04007183A MXPA04007183A (es) 2002-01-25 2002-01-25 Composicion farmaceutica para el control de la glucosa en sangre de pacientes con diabetes tipo 2.
PCT/MX2002/000003 WO2003061643A1 (es) 2002-01-25 2002-01-25 Composicion farmaceutica para el control de la glucosa en sangre de pacientes con diabetes tipo 2

Publications (1)

Publication Number Publication Date
BRPI0502691A true BRPI0502691A (pt) 2006-03-07

Family

ID=27607097

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0502691-1A BRPI0502691A (pt) 2002-01-25 2005-07-08 composição farmacêutica para o controle da glicose no sangue de pacientes com diabetes tipo 2

Country Status (11)

Country Link
US (2) US9045438B2 (pt)
EP (1) EP1482919B1 (pt)
AT (1) ATE361065T1 (pt)
BR (1) BRPI0502691A (pt)
CY (1) CY1106771T1 (pt)
DE (1) DE60219963T2 (pt)
DK (1) DK1482919T3 (pt)
ES (1) ES2284829T3 (pt)
MX (1) MXPA04007183A (pt)
PT (1) PT1482919E (pt)
WO (1) WO2003061643A1 (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2284829T3 (es) 2002-01-25 2007-11-16 Laboratorios Silanes, S.A. De C.V. Composicion farmaceutica que se usa para controlar la glucosa en sangre en pacientes con diabetes de tipo 2.
WO2003105809A1 (en) 2002-06-17 2003-12-24 Themis Laboratories Private Limited Multilayer tablets containing thiazolidinedione and biguanides and methods for producing them
MXPA05009633A (es) * 2005-09-08 2007-03-07 Silanes Sa De Cv Lab Composicion farmaceutica estable de glimepirida de liberacion inmediata y metformina de liberacion prolongada.
FR2896157B1 (fr) * 2006-01-13 2008-09-12 Merck Sante Soc Par Actions Si Combinaison de derives de triazine et d'agents de stimulation de secretion d'insuline.
US20120095059A1 (en) * 2010-04-13 2012-04-19 Jorge Luis Rosado Compositions and Methods for Treating Type II Diabetes and Related Disorders
MX339374B (es) * 2011-04-29 2016-05-13 Inst De Investigación En Química Aplic S A De C V Cocristales ionicos con base en metformina.
US9897565B1 (en) 2012-09-11 2018-02-20 Aseko, Inc. System and method for optimizing insulin dosages for diabetic subjects
US9171343B1 (en) 2012-09-11 2015-10-27 Aseko, Inc. Means and method for improved glycemic control for diabetic patients
EP2712628B1 (en) * 2012-09-28 2016-08-10 Shanta Banerjee Composition for use as a medicine or dietetic food, in particular in the prevention and/or treatment of Diabetes and diabetes associated diseases
US9233204B2 (en) 2014-01-31 2016-01-12 Aseko, Inc. Insulin management
US9486580B2 (en) 2014-01-31 2016-11-08 Aseko, Inc. Insulin management
US11081226B2 (en) 2014-10-27 2021-08-03 Aseko, Inc. Method and controller for administering recommended insulin dosages to a patient
JP6989262B2 (ja) 2014-10-27 2022-01-05 アセコー インコーポレイテッド 皮下外来患者管理
WO2016168388A2 (en) 2015-04-14 2016-10-20 Palatin Technologies, Inc. Therapies for obesity, diabetes and related indications
CA2993275C (en) 2015-08-20 2022-06-21 Aseko, Inc. Diabetes management therapy advisor

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3072527A (en) * 1959-07-01 1963-01-08 Horner Frank W Ltd Use of tolbutamide in the treatment of acne
JP3465247B2 (ja) * 1992-12-28 2003-11-10 アベンティス ファーマ株式会社 動脈硬化症の予防および治療剤
DE4432757A1 (de) * 1994-09-14 1996-03-21 Boehringer Mannheim Gmbh Pharmazeutische Zubereitung enthaltend Metformin und Verfahren zu deren Herstellung
US6348469B1 (en) * 1995-04-14 2002-02-19 Pharma Pass Llc Solid compositions containing glipizide and polyethylene oxide
IT1276130B1 (it) 1995-11-14 1997-10-27 Gentili Ist Spa Associazione glibenclamide-metformina, composizioni farmaceutiche che la contengono e loro uso nel trattamento del diabete mellito di tipo
US6011049A (en) * 1997-02-19 2000-01-04 Warner-Lambert Company Combinations for diabetes
ATE261935T1 (de) * 1997-12-08 2004-04-15 Bristol Myers Squibb Co Neue metformin salze und verfahren
DK0974356T3 (da) * 1998-07-15 2003-10-27 Merck Sante Sas Tabletter omfattende en kombination af metformin og glibenclamid
DE19860698A1 (de) * 1998-12-30 2000-07-06 Hexal Ag Neue pharmazeutische Zusammensetzung
US6559188B1 (en) * 1999-09-17 2003-05-06 Novartis Ag Method of treating metabolic disorders especially diabetes, or a disease or condition associated with diabetes
US6586438B2 (en) * 1999-11-03 2003-07-01 Bristol-Myers Squibb Co. Antidiabetic formulation and method
US6499984B1 (en) * 2000-05-22 2002-12-31 Warner-Lambert Company Continuous production of pharmaceutical granulation
BR0113102A (pt) * 2000-08-07 2003-07-08 Ranbaxy Signature Llc Formulação lìquida de metformina
FR2825023B1 (fr) * 2001-05-23 2005-04-15 Flamel Tech Sa Forme pharmaceutique orale antidiabetique "une prise par jour"comprenant une biguanide et au moins un autre principe actif
ES2284829T3 (es) 2002-01-25 2007-11-16 Laboratorios Silanes, S.A. De C.V. Composicion farmaceutica que se usa para controlar la glucosa en sangre en pacientes con diabetes de tipo 2.
US6682759B2 (en) * 2002-02-01 2004-01-27 Depomed, Inc. Manufacture of oral dosage forms delivering both immediate-release and sustained-release drugs
US20030187074A1 (en) * 2002-03-04 2003-10-02 Javed Hussain Oral compositions for treatment of diabetes
US20060002998A1 (en) 2002-11-15 2006-01-05 Anupam Trehan Pharmaceutical dosage forms of biguanide-sulfonylurea combinations
MXPA05009633A (es) * 2005-09-08 2007-03-07 Silanes Sa De Cv Lab Composicion farmaceutica estable de glimepirida de liberacion inmediata y metformina de liberacion prolongada.

Also Published As

Publication number Publication date
DE60219963T2 (de) 2008-02-07
PT1482919E (pt) 2007-07-25
ES2284829T3 (es) 2007-11-16
DE60219963D1 (de) 2007-06-14
US20050239887A1 (en) 2005-10-27
EP1482919A1 (en) 2004-12-08
ATE361065T1 (de) 2007-05-15
US20160051511A1 (en) 2016-02-25
MXPA04007183A (es) 2006-03-06
US9045438B2 (en) 2015-06-02
EP1482919B1 (en) 2007-05-02
WO2003061643A1 (es) 2003-07-31
CY1106771T1 (el) 2012-05-23
DK1482919T3 (da) 2007-07-30

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Free format text: DESCONHECO A PETICAO NO 020100046800 DE 26/05/2010, COM BASE NO DISPOSTO NO ART. 219, II DA LEI DA PROPRIEDADE INDUSTRIAL, UMA VEZ QUE O INTERESSADO NAO TEM LEGITIMIDADE PARA O ATO.

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Free format text: REFERENTE AO DESPACHO 15.24 PUBLICADO NA RPI NO 2062 DE13/07/2010.

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Free format text: DESCONHECO A PETICAO NO 020100064800 DE 26/05/201, COM BASE NO DISPOSITIVO NO ART. 219, II DA LEI DA PROPRIEDADE INDUSTRIAL, UMA VEZ QUE O INTERESSADO NAO TEM LEGITIMIDADE PARA O ATO.

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

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B06G Technical and formal requirements: other requirements [chapter 6.7 patent gazette]

Free format text: PARA QUE SEJA APROVEITADA PETICAO 018140013708 DE 22/07/2014, O SIGNATARIO DEVERA APRESENTAR INSTRUMENTO LEGAL QUE COMPROVE PODERES PARA REPRESENTAR O DEPOSITANTE NA DATA DO PROTOCOLO.

B08G Application fees: restoration [chapter 8.7 patent gazette]
B08E Application fees: payment of additional fee required [chapter 8.5 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
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B06T Formal requirements before examination [chapter 6.20 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B06I Publication of requirement cancelled [chapter 6.9 patent gazette]
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