BRPI0509028A - processo para produção de derivados de c-glicosìdeo de flavona - Google Patents
processo para produção de derivados de c-glicosìdeo de flavonaInfo
- Publication number
- BRPI0509028A BRPI0509028A BRPI0509028-8A BRPI0509028A BRPI0509028A BR PI0509028 A BRPI0509028 A BR PI0509028A BR PI0509028 A BRPI0509028 A BR PI0509028A BR PI0509028 A BRPI0509028 A BR PI0509028A
- Authority
- BR
- Brazil
- Prior art keywords
- flavone
- salt
- formula
- derivative represented
- production
- Prior art date
Links
- GAMYVSCDDLXAQW-AOIWZFSPSA-N Thermopsosid Natural products O(C)c1c(O)ccc(C=2Oc3c(c(O)cc(O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@H](CO)O4)c3)C(=O)C=2)c1 GAMYVSCDDLXAQW-AOIWZFSPSA-N 0.000 title abstract 5
- 229930003944 flavone Natural products 0.000 title abstract 5
- 235000011949 flavones Nutrition 0.000 title abstract 5
- VHBFFQKBGNRLFZ-UHFFFAOYSA-N vitamin p Natural products O1C2=CC=CC=C2C(=O)C=C1C1=CC=CC=C1 VHBFFQKBGNRLFZ-UHFFFAOYSA-N 0.000 title abstract 5
- 150000002212 flavone derivatives Chemical class 0.000 title 1
- 229930182476 C-glycoside Natural products 0.000 abstract 4
- -1 flavone C-glycoside Chemical class 0.000 abstract 4
- 150000003839 salts Chemical class 0.000 abstract 4
- 230000003266 anti-allergic effect Effects 0.000 abstract 1
- 235000008216 herbs Nutrition 0.000 abstract 1
- 239000002994 raw material Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- PZKISQRTNNHUGF-UHFFFAOYSA-N vitexine Natural products OC1C(O)C(O)C(CO)OC1OC1=C(O)C=C(O)C2=C1OC(C=1C=CC(O)=CC=1)=CC2=O PZKISQRTNNHUGF-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/12—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains three hetero rings
- C07D493/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
PROCESSO PARA PRODUçãO DE DERIVADOS DE C-GLICOSìDEO DE FLAVONA. A presente invenção refere-se a processos de produção de maneira eficiente de um derivado de C-glicosídeo de flavona representado pela fórmula (1), ou um sal do mesmo, e de um derivado de C-glicosídeo de flavona representado pela fórmula (4), ou um sal do mesmo, que são substâncias tendo um efeito antialérgico. De acordo com a presente invenção, o derivado de C-glicosídeo de flavona representado pela fórmula (1), ou o sal do mesmo, e o derivado de C-glicosídeo de flavona representado pela fórmula (4), ou o sal do mesmo, podem ser facilmente sintetizados, com bom rendimento, com isovitexina e vitexina contidas em ervas ou os similares, como matérias-primas.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004107760A JP2005289888A (ja) | 2004-03-31 | 2004-03-31 | フラボンｃ配糖体誘導体の製造方法 |
| PCT/JP2005/005695 WO2005095416A1 (ja) | 2004-03-31 | 2005-03-28 | フラボンｃ配糖体誘導体の製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0509028A true BRPI0509028A (pt) | 2007-08-07 |
Family
ID=35063707
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0509028-8A BRPI0509028A (pt) | 2004-03-31 | 2005-03-28 | processo para produção de derivados de c-glicosìdeo de flavona |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20080242855A1 (pt) |
| EP (1) | EP1731522A4 (pt) |
| JP (1) | JP2005289888A (pt) |
| KR (1) | KR20070009597A (pt) |
| CN (1) | CN100522969C (pt) |
| BR (1) | BRPI0509028A (pt) |
| CA (1) | CA2561401A1 (pt) |
| SG (1) | SG151297A1 (pt) |
| TW (1) | TW200536856A (pt) |
| WO (1) | WO2005095416A1 (pt) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005314260A (ja) * | 2004-04-28 | 2005-11-10 | Japan Science & Technology Agency | フラボンｃ配糖体の製法 |
| JP2008239513A (ja) * | 2007-03-26 | 2008-10-09 | Shizuokaken Koritsu Daigaku Hojin | 効率的フラボン構築に基づくＣｈａｆｕｒｏｓｉｄｅの新規製造法 |
| EP2385049A4 (en) * | 2009-01-03 | 2012-08-08 | Shizuoka Prefecture Public University Corp | SULFATED C-GLYCOSIDE, METHOD FOR THE ISOLATION THEREOF AND METHOD FOR THE SYNTHESIS THEREOF |
| JP5678640B2 (ja) * | 2010-12-17 | 2015-03-04 | 静岡県公立大学法人 | チャフロサイド類の簡易製造方法 |
| CN103687585B (zh) * | 2011-04-12 | 2015-11-25 | 株式会社资生堂 | 美白剂及黑素生成抑制剂 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3023962B2 (ja) | 1989-11-13 | 2000-03-21 | 株式会社伊藤園 | 抗アレルギー剤 |
| JPH10175874A (ja) * | 1996-12-19 | 1998-06-30 | Suntory Ltd | 抗アレルギー剤 |
| JP4549009B2 (ja) * | 2002-07-03 | 2010-09-22 | サントリーホールディングス株式会社 | フラボンｃ配糖体の新規誘導体及びそれを含有する組成物 |
| JP2006176407A (ja) * | 2003-04-18 | 2006-07-06 | Daiichi Asubio Pharma Co Ltd | 新規フラボン誘導体、その製造法およびそれらを含む医薬組成物 |
-
2004
- 2004-03-31 JP JP2004107760A patent/JP2005289888A/ja not_active Withdrawn
-
2005
- 2005-03-28 KR KR1020067019986A patent/KR20070009597A/ko not_active Withdrawn
- 2005-03-28 CN CNB2005800106043A patent/CN100522969C/zh not_active Expired - Fee Related
- 2005-03-28 US US10/593,743 patent/US20080242855A1/en not_active Abandoned
- 2005-03-28 EP EP05721621A patent/EP1731522A4/en not_active Withdrawn
- 2005-03-28 CA CA002561401A patent/CA2561401A1/en not_active Abandoned
- 2005-03-28 SG SG200901982-9A patent/SG151297A1/en unknown
- 2005-03-28 WO PCT/JP2005/005695 patent/WO2005095416A1/ja not_active Ceased
- 2005-03-28 BR BRPI0509028-8A patent/BRPI0509028A/pt not_active IP Right Cessation
- 2005-03-29 TW TW094109811A patent/TW200536856A/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TW200536856A (en) | 2005-11-16 |
| CN1938318A (zh) | 2007-03-28 |
| WO2005095416A1 (ja) | 2005-10-13 |
| CN100522969C (zh) | 2009-08-05 |
| EP1731522A4 (en) | 2009-05-27 |
| KR20070009597A (ko) | 2007-01-18 |
| SG151297A1 (en) | 2009-04-30 |
| JP2005289888A (ja) | 2005-10-20 |
| EP1731522A1 (en) | 2006-12-13 |
| CA2561401A1 (en) | 2005-10-13 |
| US20080242855A1 (en) | 2008-10-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B25A | Requested transfer of rights approved |
Owner name: SUNTORY HOLDINGS LIMITED (JP) Free format text: TRANSFERIDO DE: SUNTORY LIMITED |
|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 6A E 7A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2158 DE 15/05/2012. |