CR10092A - Nuevos derivados de furopirimidina aciclicos sustituidos y su uso - Google Patents
Nuevos derivados de furopirimidina aciclicos sustituidos y su usoInfo
- Publication number
- CR10092A CR10092A CR10092A CR10092A CR10092A CR 10092 A CR10092 A CR 10092A CR 10092 A CR10092 A CR 10092A CR 10092 A CR10092 A CR 10092A CR 10092 A CR10092 A CR 10092A
- Authority
- CR
- Costa Rica
- Prior art keywords
- derivatives
- furopirimidine
- aciclic
- new substituted
- treatment
- Prior art date
Links
- 238000011282 treatment Methods 0.000 abstract 4
- 238000011321 prophylaxis Methods 0.000 abstract 3
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 208000024172 Cardiovascular disease Diseases 0.000 abstract 1
- -1 acyclic furopyrimidine derivatives Chemical class 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 229940126601 medicinal product Drugs 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
La presente solicitud se refiere a nuevos derivados de furopirimidina acíclicos sustituidos, a procedimientos para su producción, a su uso para el tratamiento y/o la profilaxis de enfermedades, así como a su uso para la preparación de producto medicinal para el tratameitno y/o la profilaxis de enfermedades, en particular para el tratamiento y/o profilaxis de enfermedades cardiovasculares.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102005061170A DE102005061170A1 (de) | 2005-12-21 | 2005-12-21 | Neue, acyclisch substituierte Furopyrimidin-Derivate und ihre Verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CR10092A true CR10092A (es) | 2008-10-08 |
Family
ID=37876878
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CR10092A CR10092A (es) | 2005-12-21 | 2008-06-20 | Nuevos derivados de furopirimidina aciclicos sustituidos y su uso |
Country Status (31)
| Country | Link |
|---|---|
| US (1) | US8183246B2 (es) |
| EP (1) | EP1966217B1 (es) |
| JP (1) | JP5254032B2 (es) |
| KR (1) | KR101429777B1 (es) |
| CN (1) | CN101384603B (es) |
| AR (1) | AR058108A1 (es) |
| AU (1) | AU2006334856B2 (es) |
| BR (1) | BRPI0620317A2 (es) |
| CA (1) | CA2633701C (es) |
| CR (1) | CR10092A (es) |
| DE (1) | DE102005061170A1 (es) |
| DK (1) | DK1966217T3 (es) |
| DO (1) | DOP2006000280A (es) |
| EC (1) | ECSP088569A (es) |
| ES (1) | ES2418855T3 (es) |
| GT (1) | GT200800117A (es) |
| IL (1) | IL192062A0 (es) |
| MA (1) | MA30039B1 (es) |
| NO (1) | NO20082986L (es) |
| NZ (1) | NZ569214A (es) |
| PE (1) | PE20071168A1 (es) |
| PL (1) | PL1966217T3 (es) |
| PT (1) | PT1966217E (es) |
| RU (1) | RU2454419C2 (es) |
| SV (1) | SV2009002953A (es) |
| TN (1) | TNSN08279A1 (es) |
| TW (1) | TWI405764B (es) |
| UA (1) | UA94080C2 (es) |
| UY (1) | UY30046A1 (es) |
| WO (1) | WO2007079862A1 (es) |
| ZA (1) | ZA200805385B (es) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102007019691A1 (de) * | 2007-04-26 | 2008-10-30 | Bayer Healthcare Ag | Verwendung von acyclisch substituierten Furopyrimidin-Derivaten zur Behandlung der pulmonalen arteriellen Hypertonie |
| DE102007027799A1 (de) * | 2007-06-16 | 2008-12-18 | Bayer Healthcare Ag | Substituierte Furopyrimidine und ihre Verwendung |
| DE102007051762A1 (de) | 2007-10-30 | 2009-05-07 | Bayer Healthcare Ag | Substituierte Pyrrolotriazine und ihre Verwendung |
| DE102007054786A1 (de) * | 2007-11-16 | 2009-05-20 | Bayer Healthcare Ag | Trisubstituierte Furopyrimidine und ihre Verwendung |
| US9505772B2 (en) | 2012-05-10 | 2016-11-29 | Takeda Pharmaceutical Company Limited | Aromatic ring compound |
| EP2848621A4 (en) | 2012-05-10 | 2016-06-01 | Takeda Pharmaceutical | AROMATIC RING CONNECTION |
| KR102590848B1 (ko) | 2016-12-28 | 2023-10-19 | 다트 뉴로사이언스, 엘엘씨 | Pde2 억제제로서 치환된 피라졸로피리미디논 화합물 |
| DK3717488T3 (da) | 2017-11-27 | 2021-12-13 | Dart Neuroscience Llc | Substituerede furanopyrimidinforbindelser som pde1-inhibitorer |
| WO2020231990A1 (en) * | 2019-05-13 | 2020-11-19 | Relay Therapeutics, Inc. | Fgfr inhibitors and methods of use thereof |
| KR102094337B1 (ko) | 2019-10-01 | 2020-03-27 | 안문호 | 금속이물질 제거장치 |
| TW202233625A (zh) | 2020-11-18 | 2022-09-01 | 美商傳達治療有限公司 | Ｆｇｆｒ抑制劑及其製造及使用方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3577420A (en) | 1968-01-05 | 1971-05-04 | Pfizer | Certain 4-aminofuro(2,3-d)pyrimidines |
| WO2000005234A1 (en) | 1998-07-22 | 2000-02-03 | Suntory Limited | NF-λB INHIBITORS CONTAINING INDAN DERIVATIVES AS THE ACTIVE INGREDIENT |
| WO2000075145A1 (en) | 1999-06-03 | 2000-12-14 | Abbott Laboratories | Cell adhesion-inhibiting antiinflammatory compounds |
| CN1212861C (zh) | 1999-09-17 | 2005-08-03 | 第一三得利制药株式会社 | 以NF－κB抑制剂为有效成分的心肌炎、扩张型心肌病和心衰的预防或治疗药 |
| DK1390371T3 (da) | 2001-05-14 | 2006-06-19 | Novartis Ag | Oxazolo- og furopyrimidiner samt deres anvendelse i lægemidler mod tumorer |
| DE10141212A1 (de) * | 2001-08-22 | 2003-03-06 | Bayer Ag | Neue 4-Aminofuropyrimidine und ihre Verwendung |
| AU2002333524A1 (en) | 2001-09-11 | 2003-03-24 | Glaxosmithkline K.K. | Furo-and thienopyrimidine derivatives as angiogenesis inhibitors |
| DE10148883A1 (de) * | 2001-10-04 | 2003-04-10 | Merck Patent Gmbh | Pyrimidinderivate |
| US20030225098A1 (en) * | 2002-03-21 | 2003-12-04 | Hirst Gavin C. | Kinase inhibitors |
| KR20050091462A (ko) | 2004-03-12 | 2005-09-15 | 한국과학기술연구원 | 푸로피리미딘 화합물 및 이를 포함하는 ｄｄｒ2 티로신키나아제 활성 저해제 |
| MXPA06014256A (es) | 2004-06-10 | 2007-03-12 | Xention Discovery Ltd | Compuestos de furano-pirimidina efectivos como inhibidores del canal de potasio. |
| MXPA06015223A (es) * | 2004-06-29 | 2007-11-09 | Amgen Inc | Furanopirimidinas. |
-
2005
- 2005-12-21 DE DE102005061170A patent/DE102005061170A1/de not_active Withdrawn
-
2006
- 2006-12-08 CA CA2633701A patent/CA2633701C/en not_active Expired - Fee Related
- 2006-12-08 PL PL06829427T patent/PL1966217T3/pl unknown
- 2006-12-08 EP EP06829427.1A patent/EP1966217B1/de not_active Not-in-force
- 2006-12-08 US US12/086,783 patent/US8183246B2/en not_active Expired - Fee Related
- 2006-12-08 BR BRPI0620317-5A patent/BRPI0620317A2/pt not_active IP Right Cessation
- 2006-12-08 KR KR1020087017526A patent/KR101429777B1/ko not_active Expired - Fee Related
- 2006-12-08 PT PT68294271T patent/PT1966217E/pt unknown
- 2006-12-08 DK DK06829427.1T patent/DK1966217T3/da active
- 2006-12-08 UA UAA200809519A patent/UA94080C2/ru unknown
- 2006-12-08 WO PCT/EP2006/011826 patent/WO2007079862A1/de not_active Ceased
- 2006-12-08 ES ES06829427T patent/ES2418855T3/es active Active
- 2006-12-08 CN CN2006800532242A patent/CN101384603B/zh not_active Expired - Fee Related
- 2006-12-08 RU RU2008129363/04A patent/RU2454419C2/ru not_active IP Right Cessation
- 2006-12-08 JP JP2008546193A patent/JP5254032B2/ja not_active Expired - Fee Related
- 2006-12-08 AU AU2006334856A patent/AU2006334856B2/en not_active Ceased
- 2006-12-08 NZ NZ569214A patent/NZ569214A/en not_active IP Right Cessation
- 2006-12-14 DO DO2006000280A patent/DOP2006000280A/es unknown
- 2006-12-18 AR ARP060105587A patent/AR058108A1/es not_active Application Discontinuation
- 2006-12-20 PE PE2006001653A patent/PE20071168A1/es not_active Application Discontinuation
- 2006-12-20 UY UY30046A patent/UY30046A1/es not_active Application Discontinuation
- 2006-12-20 TW TW095147761A patent/TWI405764B/zh not_active IP Right Cessation
-
2008
- 2008-06-11 IL IL192062A patent/IL192062A0/en unknown
- 2008-06-11 MA MA31016A patent/MA30039B1/fr unknown
- 2008-06-19 GT GT200800117A patent/GT200800117A/es unknown
- 2008-06-19 SV SV2008002953A patent/SV2009002953A/es not_active Application Discontinuation
- 2008-06-20 CR CR10092A patent/CR10092A/es not_active Application Discontinuation
- 2008-06-20 EC EC2008008569A patent/ECSP088569A/es unknown
- 2008-06-20 ZA ZA200805385A patent/ZA200805385B/xx unknown
- 2008-06-20 TN TNP2008000279A patent/TNSN08279A1/en unknown
- 2008-07-02 NO NO20082986A patent/NO20082986L/no not_active Application Discontinuation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal (granting procedure) |