BRPI0510515A - compostos de morfolina - Google Patents

compostos de morfolina

Info

Publication number
BRPI0510515A
BRPI0510515A BRPI0510515-3A BRPI0510515A BRPI0510515A BR PI0510515 A BRPI0510515 A BR PI0510515A BR PI0510515 A BRPI0510515 A BR PI0510515A BR PI0510515 A BRPI0510515 A BR PI0510515A
Authority
BR
Brazil
Prior art keywords
compounds
formula
morpholine compounds
morpholine
adhd
Prior art date
Application number
BRPI0510515-3A
Other languages
English (en)
Inventor
Paul Vincent Fish
Malcolm Christian Mackenny
Alan Stobie
Florian Wakenhut
Gavin Alistair Whitlock
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32482498&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0510515(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer filed Critical Pfizer
Publication of BRPI0510515A publication Critical patent/BRPI0510515A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
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    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
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    • C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
    • C—CHEMISTRY; METALLURGY
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Psychology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)

Abstract

COMPOSTOS DE MORFOLINA. A presente invenção fornece compostos de Fórmula I: em que R¬ 1¬, R¬ 2¬, R¬ 3¬, e n têm qualquer dos valores definidos na especificação, e sais farmaceuticamente aceitáveis destes, que são úteis como agentes no tratamento de condições incluindo distúrbios urinários, dor, ejaculação prematura, ADHD e fibromialgia. Também são fornecidas composições farmacêuticas compreendendo um ou mais compostos de Fórmula I.
BRPI0510515-3A 2004-04-30 2005-04-20 compostos de morfolina BRPI0510515A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0409744.0A GB0409744D0 (en) 2004-04-30 2004-04-30 Novel compounds
PCT/IB2005/001154 WO2005105100A1 (en) 2004-04-30 2005-04-20 Morpholine compounds

Publications (1)

Publication Number Publication Date
BRPI0510515A true BRPI0510515A (pt) 2007-10-30

Family

ID=32482498

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0510515-3A BRPI0510515A (pt) 2004-04-30 2005-04-20 compostos de morfolina

Country Status (33)

Country Link
US (3) US20050250775A1 (pt)
EP (1) EP1744754A1 (pt)
JP (2) JP4181622B2 (pt)
KR (4) KR20090006887A (pt)
CN (1) CN1950089A (pt)
AP (1) AP2006003767A0 (pt)
AR (1) AR048934A1 (pt)
AU (1) AU2005237301A1 (pt)
BR (1) BRPI0510515A (pt)
CA (1) CA2564990C (pt)
CR (1) CR8717A (pt)
DO (1) DOP2005000064A (pt)
EA (1) EA200601802A1 (pt)
EC (1) ECSP066958A (pt)
GB (1) GB0409744D0 (pt)
GE (1) GEP20084549B (pt)
GT (1) GT200500098A (pt)
IL (1) IL178313A0 (pt)
MA (1) MA28554B1 (pt)
MX (1) MXPA06012640A (pt)
NI (1) NI200600257A (pt)
NL (1) NL1028927C2 (pt)
NO (1) NO20064282L (pt)
NZ (1) NZ550054A (pt)
PA (1) PA8631601A1 (pt)
PE (1) PE20060305A1 (pt)
SV (1) SV2005002099A (pt)
TN (1) TNSN06347A1 (pt)
TW (2) TWI309165B (pt)
UA (1) UA86970C2 (pt)
UY (1) UY28873A1 (pt)
WO (1) WO2005105100A1 (pt)
ZA (1) ZA200608661B (pt)

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GB0409744D0 (en) * 2004-04-30 2004-06-09 Pfizer Ltd Novel compounds
AP2006003771A0 (en) * 2004-04-30 2006-10-31 Warner Lambert Co Substituted morpholine compounds for the treatmentof central nervous system disorders
US8389510B2 (en) * 2005-11-18 2013-03-05 Astrazeneca Ab Crystalline forms
EP1951257A4 (en) * 2005-11-18 2008-11-05 Astrazeneca Ab CRYSTALLINE FORMS
WO2007062338A2 (en) * 2005-11-18 2007-05-31 Astrazeneca Ab Solid formulations
EP1951694A4 (en) * 2005-11-18 2010-09-22 Astrazeneca Ab FORMS OF SALTS
JP2009516708A (ja) * 2005-11-18 2009-04-23 アストラゼネカ・アクチエボラーグ 液体製剤
JP5268652B2 (ja) * 2006-02-01 2013-08-21 メルク・シャープ・アンド・ドーム・コーポレーション カリウムチャンネルインヒビター
EP1892530A1 (en) * 2006-08-25 2008-02-27 Boehringer Ingelheim Pharma GmbH & Co. KG Method for determining transport activity of a transport protein
KR101103118B1 (ko) * 2007-11-02 2012-01-04 동아제약주식회사 신규한 1,3-디히드로-5-이소벤조퓨란카르보니트릴 유도체 화합물 및 이를 함유하는 조루증 치료용 약학조성물
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