DOP2005000064A - Nuevos compuestos - Google Patents

Nuevos compuestos

Info

Publication number
DOP2005000064A
DOP2005000064A DO2005000064A DO2005000064A DOP2005000064A DO P2005000064 A DOP2005000064 A DO P2005000064A DO 2005000064 A DO2005000064 A DO 2005000064A DO 2005000064 A DO2005000064 A DO 2005000064A DO P2005000064 A DOP2005000064 A DO P2005000064A
Authority
DO
Dominican Republic
Prior art keywords
new compounds
formula
compounds
adhd
fibromyalgia
Prior art date
Application number
DO2005000064A
Other languages
English (en)
Inventor
Paul Vicent Fish
Malcolm Christian Mackenny
Alan Stobie
Florian Wakenhut
Gavin Alistair Whitlock
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32482498&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DOP2005000064(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer filed Critical Pfizer
Publication of DOP2005000064A publication Critical patent/DOP2005000064A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
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    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
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    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Obesity (AREA)
  • Psychology (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Hospice & Palliative Care (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Anesthesiology (AREA)

Abstract

La presente invención proporciona compuestos de Fórmula I: en la que R1, R2, R3, y n tienen cualquiera de los valores definidos en la memoria descriptiva, y sales farmacéuticamente aceptables de los mismos, que son útiles como agentes en el tratamiento de afecciones que incluyen trastornos urinarios, dolor, eyaculación precoz, ADHD y fibromialgia. Tambien se proporcionan composiciones farmaceuticas que comprenden uno o màs compuestos de Fórmula I.
DO2005000064A 2004-04-30 2005-04-15 Nuevos compuestos DOP2005000064A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0409744.0A GB0409744D0 (en) 2004-04-30 2004-04-30 Novel compounds

Publications (1)

Publication Number Publication Date
DOP2005000064A true DOP2005000064A (es) 2005-11-01

Family

ID=32482498

Family Applications (1)

Application Number Title Priority Date Filing Date
DO2005000064A DOP2005000064A (es) 2004-04-30 2005-04-15 Nuevos compuestos

Country Status (33)

Country Link
US (3) US20050250775A1 (es)
EP (1) EP1744754A1 (es)
JP (2) JP4181622B2 (es)
KR (4) KR20090006889A (es)
CN (1) CN1950089A (es)
AP (1) AP2006003767A0 (es)
AR (1) AR048934A1 (es)
AU (1) AU2005237301A1 (es)
BR (1) BRPI0510515A (es)
CA (1) CA2564990C (es)
CR (1) CR8717A (es)
DO (1) DOP2005000064A (es)
EA (1) EA200601802A1 (es)
EC (1) ECSP066958A (es)
GB (1) GB0409744D0 (es)
GE (1) GEP20084549B (es)
GT (1) GT200500098A (es)
IL (1) IL178313A0 (es)
MA (1) MA28554B1 (es)
MX (1) MXPA06012640A (es)
NI (1) NI200600257A (es)
NL (1) NL1028927C2 (es)
NO (1) NO20064282L (es)
NZ (1) NZ550054A (es)
PA (1) PA8631601A1 (es)
PE (1) PE20060305A1 (es)
SV (1) SV2005002099A (es)
TN (1) TNSN06347A1 (es)
TW (2) TWI309165B (es)
UA (1) UA86970C2 (es)
UY (1) UY28873A1 (es)
WO (1) WO2005105100A1 (es)
ZA (1) ZA200608661B (es)

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AU2005238296A1 (en) 2004-04-30 2005-11-10 Warner-Lambert Company Llc Substituted morpholine compounds for the treatment of central nervous system disorders
GB0409744D0 (en) * 2004-04-30 2004-06-09 Pfizer Ltd Novel compounds
JP2009516707A (ja) * 2005-11-18 2009-04-23 アストラゼネカ・アクチエボラーグ 固形製剤
US20090069291A1 (en) * 2005-11-18 2009-03-12 Astrazeneca Ab Salt Forms
EP1951257A4 (en) * 2005-11-18 2008-11-05 Astrazeneca Ab CRYSTALLINE FORMS
JP2009516708A (ja) * 2005-11-18 2009-04-23 アストラゼネカ・アクチエボラーグ 液体製剤
US8389510B2 (en) * 2005-11-18 2013-03-05 Astrazeneca Ab Crystalline forms
US8030332B2 (en) * 2006-02-01 2011-10-04 Merck Sharp & Dohme Corp. Potassium channel inhibitors
EP1892530A1 (en) * 2006-08-25 2008-02-27 Boehringer Ingelheim Pharma GmbH & Co. KG Method for determining transport activity of a transport protein
KR101103118B1 (ko) * 2007-11-02 2012-01-04 동아제약주식회사 신규한 1,3-디히드로-5-이소벤조퓨란카르보니트릴 유도체 화합물 및 이를 함유하는 조루증 치료용 약학조성물
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