BRPI0511956A - processo para a preparação dos compostos, e, intermediários de sìntese - Google Patents

processo para a preparação dos compostos, e, intermediários de sìntese

Info

Publication number
BRPI0511956A
BRPI0511956A BRPI0511956-1A BRPI0511956A BRPI0511956A BR PI0511956 A BRPI0511956 A BR PI0511956A BR PI0511956 A BRPI0511956 A BR PI0511956A BR PI0511956 A BRPI0511956 A BR PI0511956A
Authority
BR
Brazil
Prior art keywords
compounds
preparation
synthesis intermediates
formula
synthesis
Prior art date
Application number
BRPI0511956-1A
Other languages
English (en)
Inventor
Francoise Lurquin
Frank Driessens
Michel Callaert
Original Assignee
Ucb Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ucb Sa filed Critical Ucb Sa
Publication of BRPI0511956A publication Critical patent/BRPI0511956A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

PROCESSO PARA A PREPARAçãO DOS COMPOSTOS, E, INTERMEDIáRIOS DE SìNTESE. A presente invenção refere-se a um novo processo para preparar derivados de 2-oxo-1-pirrolidina de fórmula geral (I), compreendendo a ciclização de um intermediário de fórmula geral (II), em que os substituintes são como definidos na especificação.
BRPI0511956-1A 2004-06-11 2005-05-26 processo para a preparação dos compostos, e, intermediários de sìntese BRPI0511956A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04013715 2004-06-11
PCT/EP2005/005689 WO2005121082A1 (en) 2004-06-11 2005-05-26 Process for preparing 2-oxo-1-pyrrolidine derivatives by intramolecular allylation

Publications (1)

Publication Number Publication Date
BRPI0511956A true BRPI0511956A (pt) 2008-01-22

Family

ID=34925330

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0511956-1A BRPI0511956A (pt) 2004-06-11 2005-05-26 processo para a preparação dos compostos, e, intermediários de sìntese

Country Status (15)

Country Link
US (1) US7612215B2 (pt)
EP (1) EP1758855B1 (pt)
JP (1) JP4866352B2 (pt)
KR (1) KR101159870B1 (pt)
CN (1) CN1964942A (pt)
AU (1) AU2005251884B2 (pt)
BR (1) BRPI0511956A (pt)
CA (1) CA2568700A1 (pt)
DE (1) DE602005003472T2 (pt)
EA (1) EA010912B1 (pt)
ES (1) ES2296177T3 (pt)
IL (1) IL179650A0 (pt)
MX (1) MXPA06014201A (pt)
WO (1) WO2005121082A1 (pt)
ZA (1) ZA200610274B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8076493B2 (en) * 2005-12-07 2011-12-13 Ucb Pharma, S.A. 3-carboxy-2-oxo-1-pyrrolidine derivatives and their uses
US8338621B2 (en) 2005-12-21 2012-12-25 Ucb S.A. Process for the preparation of 2-oxo-1-pyrrolidine derivatives
DK2273975T3 (da) * 2008-03-03 2014-06-30 Ucb Pharma Sa Farmaceutiske opløsninger, fremgangsmåde til fremstilling og terapeutiske anvendelser
EP2346500B1 (en) 2008-10-16 2017-05-17 The Johns Hopkins University Methods and compositions for improving cognitive function
US10154988B2 (en) 2012-11-14 2018-12-18 The Johns Hopkins University Methods and compositions for treating schizophrenia
CA2904767C (en) 2013-03-15 2022-06-21 Agenebio, Inc. Methods and compositions for improving cognitive function
US10806717B2 (en) 2013-03-15 2020-10-20 The Johns Hopkins University Methods and compositions for improving cognitive function
ME03518B (me) 2014-01-21 2020-04-20 Janssen Pharmaceutica Nv Kombinacije koje obuhvataju pozitivne alosterične modulatore ili ortosterične agoniste metabotropnog glutamatergičnog receptora podtipa 2 i njihova primjena
PL3096790T3 (pl) 2014-01-21 2020-01-31 Janssen Pharmaceutica, N.V. Kombinacje zawierające pozytywne modulatory allosteryczne lub agonistów ortosterycznych metabotropowego receptora glutaminergicznego podtypu 2 i ich zastosowanie
EA034167B8 (ru) 2015-05-22 2021-04-27 Эйджинбайо, Инк. Фармацевтические композиции леветирацетама пролонгированного высвобождения
CN115141134B (zh) * 2021-03-31 2024-09-03 江西同和药业股份有限公司 一种化合物及其制备方法和应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0004297D0 (en) * 2000-02-23 2000-04-12 Ucb Sa 2-oxo-1 pyrrolidine derivatives process for preparing them and their uses

Also Published As

Publication number Publication date
WO2005121082A1 (en) 2005-12-22
ES2296177T3 (es) 2008-04-16
DE602005003472T2 (de) 2008-09-25
US7612215B2 (en) 2009-11-03
JP4866352B2 (ja) 2012-02-01
AU2005251884B2 (en) 2011-03-24
KR20070026794A (ko) 2007-03-08
KR101159870B1 (ko) 2012-06-25
MXPA06014201A (es) 2007-03-12
JP2008501740A (ja) 2008-01-24
ZA200610274B (en) 2008-06-25
AU2005251884A1 (en) 2005-12-22
CN1964942A (zh) 2007-05-16
US20080125598A1 (en) 2008-05-29
IL179650A0 (en) 2007-05-15
EA010912B1 (ru) 2008-12-30
EP1758855B1 (en) 2007-11-21
DE602005003472D1 (de) 2008-01-03
CA2568700A1 (en) 2005-12-22
EA200602169A1 (ru) 2007-06-29
EP1758855A1 (en) 2007-03-07

Similar Documents

Publication Publication Date Title
BR0307721A (pt) Processo para preparação de derivados de indolinona
BRPI0518758A2 (pt) compostos de acetamida como fungicidas
BRPI0510410A (pt) compostos orgánicos
BRPI0719367B8 (pt) processo para a preparação de nebivolol, seus intermediários e usos
BRPI0506843A (pt) composto, composição farmacêutica, processo para a preparação de um composto, e, uso de um composto
BRPI0411268C1 (pt) processo para a preparação de compostos 3-aril butil-amina substituído
BRPI0414436A (pt) processo para a preparação de derivados de 2-oxo-1-pirrolidina e seus sais
BR122019010008B8 (pt) derivados de pirimidina, seu uso, e composição e combinação farmacêuticas
BRPI0206433B8 (pt) composto, composição farmacêutica, e, uso de um composto
BRPI0519674A2 (pt) sulfonil pirrolidinas, mÉtodo para produzir as mesmas e seu uso como drogas
ECSP10010129A (es) Inhibidores de quinasas símil polo
BRPI0510412A (pt) compostos orgánicos
BRPI0813284A8 (pt) Processo para a preparação de um composto da fórmula (i) e composto
BRPI0518601A2 (pt) processo para preparaÇço de derivados de piperazin-2-ona anelados bem como produtos intermediÁrios do processo
BRPI0920834A2 (pt) processo para preparação de derivados protegidos de l-alanina
BRPI0719264B8 (pt) processo para a preparação de nebivolol
BRPI0108990B8 (pt) processo para preparação de derivados de pirimidona com atividade antifungos
BR0208534A (pt) Processo para preparação de 4,6-diaminopirimido[5,4-d]pirimidinas
ECSP088151A (es) Diazepinoquinolinas, sintesis de las mismas, e intermediarios para obtenerlas
BRPI0411209A (pt) uso de derivados isoindolinona como inseticidas
ECSP088251A (es) Diazepinoquinolinas, sintesis de las mismas, e intermediarios para obtenerlas
BRPI0411308A (pt) composto, composição farmacêutica, processo para a preparação de um composto, e, uso de um composto
BRPI0412904A (pt) processo para a preparação de inibidores de cpla2
BRPI0517390A (pt) processo para a preparação de derivados de [1,4,5]-oxadiazepina
BR0113259A (pt) Processo para a preparação de um composto, composto e processo para a preparação de compostos

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 10A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2310 DE 14-04-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.