BRPI0512239A - processos para preparação de antagonistas de receptores de hormÈnios liberadores de gonatropina - Google Patents

processos para preparação de antagonistas de receptores de hormÈnios liberadores de gonatropina

Info

Publication number
BRPI0512239A
BRPI0512239A BRPI0512239-2A BRPI0512239A BRPI0512239A BR PI0512239 A BRPI0512239 A BR PI0512239A BR PI0512239 A BRPI0512239 A BR PI0512239A BR PI0512239 A BRPI0512239 A BR PI0512239A
Authority
BR
Brazil
Prior art keywords
processes
preparing
receptor antagonists
hormone receptor
releasing hormone
Prior art date
Application number
BRPI0512239-2A
Other languages
English (en)
Inventor
Alexander V Gontcharov
Gulnaz Khafizova
John R Potoski
Donna Mary Huryn
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of BRPI0512239A publication Critical patent/BRPI0512239A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/08—Radicals containing only hydrogen and carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

PROCESSOS PARA PREPARAçãO DE ANTAGONISTAS DE RECEPTORES DE HORMÈNIOS LIBERADORES DE GONATROPINA. A presente invenção refere-se a processas para preparar antagonistas de receptores de Hormónio Liberador de Gonadotropina ("GnRH" (também conhecido como Hormónio Liberador de Hormónio Luteinizante).
BRPI0512239-2A 2004-06-17 2005-06-16 processos para preparação de antagonistas de receptores de hormÈnios liberadores de gonatropina BRPI0512239A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US58066504P 2004-06-17 2004-06-17
PCT/US2005/021127 WO2006009736A1 (en) 2004-06-17 2005-06-16 Processes for preparing gonadotropin releasing hormone receptor antagonists

Publications (1)

Publication Number Publication Date
BRPI0512239A true BRPI0512239A (pt) 2008-02-19

Family

ID=34972567

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0512239-2A BRPI0512239A (pt) 2004-06-17 2005-06-16 processos para preparação de antagonistas de receptores de hormÈnios liberadores de gonatropina

Country Status (16)

Country Link
US (1) US7714130B2 (pt)
EP (1) EP1756093A1 (pt)
JP (1) JP2008503470A (pt)
CN (1) CN1968948A (pt)
AU (1) AU2005264998A1 (pt)
BR (1) BRPI0512239A (pt)
CA (1) CA2570693A1 (pt)
CR (1) CR8786A (pt)
EC (1) ECSP067091A (pt)
IL (1) IL179993A0 (pt)
MX (1) MXPA06014797A (pt)
NO (1) NO20070248L (pt)
NZ (1) NZ552093A (pt)
RU (1) RU2007101509A (pt)
WO (1) WO2006009736A1 (pt)
ZA (1) ZA200610594B (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006009734A1 (en) * 2004-06-17 2006-01-26 Wyeth Gonadotropin releasing hormone receptor antagonists
WO2006009736A1 (en) 2004-06-17 2006-01-26 Wyeth Processes for preparing gonadotropin releasing hormone receptor antagonists
CN101048383A (zh) * 2004-11-23 2007-10-03 惠氏公司 促性腺激素释放激素受体拮抗剂
US7538113B2 (en) * 2005-02-18 2009-05-26 Wyeth 4-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor
US7534796B2 (en) * 2005-02-18 2009-05-19 Wyeth Imidazo[4,5-b]pyridine antagonists of gonadotropin releasing hormone receptor
US7582634B2 (en) * 2005-02-18 2009-09-01 Wyeth 7-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor
US20060189619A1 (en) * 2005-02-24 2006-08-24 Wyeth 3-({4-[2-(4-Tert-butylphenyl)-1h-benzimidazol-4-yl]piperazin-1-yl}methyl)pyrido[2,3-b]]pyrazi ne compounds
CA2601978A1 (en) * 2005-03-07 2006-09-14 Wyeth Quinoxaline dihydrohalide dihydrates and synthetic methods therefor
US7531542B2 (en) * 2005-05-18 2009-05-12 Wyeth Benzooxazole and benzothiazole antagonists of gonadotropin releasing hormone receptor
US7582636B2 (en) * 2005-05-26 2009-09-01 Wyeth Piperazinylimidazopyridine and piperazinyltriazolopyridine antagonists of Gonadotropin Releasing Hormone receptor
US10272070B2 (en) 2014-10-14 2019-04-30 The Board of Trustees of the Leland Stanford Junio r University Method for treating neurodegenerative diseases
CN105879033B (zh) * 2015-04-01 2019-03-26 北京大学人民医院 GnRH Ⅱ型拮抗剂在抑制孕激素耐药子宫内膜癌细胞增殖中的应用
EP3390367B1 (en) 2015-12-15 2020-09-09 The Board of Trustees of the Leland Stanford Junior University Method for preventing and/or treating aging-associated cognitive impairment and neuroinflammation
MX2021001456A (es) 2018-08-06 2021-05-27 Univ Leland Stanford Junior 2-arilbenzimidazoles como activadores de ppargc1a para tratar enfermedades neurodegenerativas.

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Also Published As

Publication number Publication date
CN1968948A (zh) 2007-05-23
RU2007101509A (ru) 2008-07-27
WO2006009736A1 (en) 2006-01-26
NO20070248L (no) 2007-01-15
CR8786A (es) 2007-08-28
MXPA06014797A (es) 2007-02-16
ECSP067091A (es) 2007-01-26
JP2008503470A (ja) 2008-02-07
ZA200610594B (en) 2008-07-30
US20050282820A1 (en) 2005-12-22
IL179993A0 (en) 2007-05-15
NZ552093A (en) 2009-06-26
CA2570693A1 (en) 2006-01-26
EP1756093A1 (en) 2007-02-28
AU2005264998A1 (en) 2006-01-26
US7714130B2 (en) 2010-05-11

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