BRPI0513005A - composições contendo nicorandil, processo de preparo e utilização - Google Patents
composições contendo nicorandil, processo de preparo e utilizaçãoInfo
- Publication number
- BRPI0513005A BRPI0513005A BRPI0513005-0A BRPI0513005A BRPI0513005A BR PI0513005 A BRPI0513005 A BR PI0513005A BR PI0513005 A BRPI0513005 A BR PI0513005A BR PI0513005 A BRPI0513005 A BR PI0513005A
- Authority
- BR
- Brazil
- Prior art keywords
- nicorandil
- preparation
- containing compositions
- compositions containing
- compositions
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 6
- 238000000034 method Methods 0.000 title abstract 4
- LBHIOVVIQHSOQN-UHFFFAOYSA-N nicorandil Chemical compound [O-][N+](=O)OCCNC(=O)C1=CC=CN=C1 LBHIOVVIQHSOQN-UHFFFAOYSA-N 0.000 title abstract 4
- 229960002497 nicorandil Drugs 0.000 title abstract 4
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 238000007907 direct compression Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
COMPOSIçõES CONTENDO NICORANDIL, PROCESSO DE PREPARO E UTILIZAçãO. Processo de preparo de composições, contendo Nicorandil, composições obtidas por esse processo e utilização. A presente invenção refere-se notadamente a um processo de preparo de composições contendo Nicorandil, composições obtidas por esse processo, comprimidos obtidos por compressão direta, e sua utilização como medicamento.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0407590A FR2872705B1 (fr) | 2004-07-08 | 2004-07-08 | Compositions contenant du nicorandil, procede de preparation et utilisation |
| PCT/FR2005/001730 WO2006016040A1 (fr) | 2004-07-08 | 2005-07-05 | Compositions contenant du nicorandil, procede de preparation et utilisation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0513005A true BRPI0513005A (pt) | 2008-04-22 |
Family
ID=34950297
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0513005-0A BRPI0513005A (pt) | 2004-07-08 | 2005-07-05 | composições contendo nicorandil, processo de preparo e utilização |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20070190134A1 (pt) |
| EP (1) | EP1776093A1 (pt) |
| JP (1) | JP2008505873A (pt) |
| KR (1) | KR20070030262A (pt) |
| CN (1) | CN100591356C (pt) |
| AU (1) | AU2005271131B2 (pt) |
| BR (1) | BRPI0513005A (pt) |
| CA (1) | CA2570863A1 (pt) |
| EA (1) | EA012967B1 (pt) |
| FR (1) | FR2872705B1 (pt) |
| IL (1) | IL180285A0 (pt) |
| MA (1) | MA28783B1 (pt) |
| MX (1) | MXPA06015151A (pt) |
| NO (1) | NO20070186L (pt) |
| NZ (1) | NZ552983A (pt) |
| WO (1) | WO2006016040A1 (pt) |
| ZA (1) | ZA200700704B (pt) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2098249B1 (en) | 2008-03-05 | 2012-10-24 | Rivopharm SA | Nicorandil carriers with enhanced stability |
| CN115429763B (zh) * | 2021-06-02 | 2024-01-02 | 北京四环科宝制药股份有限公司 | 尼可地尔片剂及其制备方法 |
| CN114732792A (zh) * | 2022-03-25 | 2022-07-12 | 北京诺康达医药科技股份有限公司 | 一种尼可地尔口腔崩解片及其制备方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3915959A (en) * | 1974-03-15 | 1975-10-28 | Crown Zellerbach Corp | Activated alkali cellulose and derivatives formed therefrom and a process for making the same |
| JPS57145659A (en) * | 1981-03-06 | 1982-09-08 | Chugai Pharmaceutical Co Ltd | Production of tablet |
| KR940000232B1 (ko) * | 1986-01-17 | 1994-01-12 | 쥬우가이세이야꾸 가부시끼가이샤 | 니코란딜 제제의 안정화 방법 |
| ZA87279B (en) * | 1986-01-17 | 1987-09-30 | Chugai Pharmaceutical Co Ltd | Method for production of stable nicorandil preparation |
| JP2512302B2 (ja) * | 1986-03-19 | 1996-07-03 | 中外製薬株式会社 | ニコランジル安定化製剤の製造方法 |
| JP2936376B2 (ja) * | 1993-09-03 | 1999-08-23 | 小林化工株式会社 | ニコランジル錠剤の製法 |
| JP3503222B2 (ja) * | 1994-11-07 | 2004-03-02 | 東和薬品株式会社 | ニコランジルの安定化錠剤の製造方法 |
| JPH08175996A (ja) * | 1994-12-22 | 1996-07-09 | Taiyo Yakuhin Kogyo Kk | ニコランジル安定化固形製剤の製法 |
| JP2535141B2 (ja) * | 1995-01-17 | 1996-09-18 | 中外製薬株式会社 | フマル酸含有徐放性製剤 |
| TW458776B (en) * | 1995-08-15 | 2001-10-11 | Chugai Pharmaceutical Co Ltd | Pharmaceutical composition for the treatment of anxiety neurosis |
| JP3947582B2 (ja) * | 1995-08-15 | 2007-07-25 | 中外製薬株式会社 | 不安神経症治療剤 |
| JPH10231241A (ja) * | 1997-02-19 | 1998-09-02 | T T S Gijutsu Kenkyusho:Kk | 服用に水を必要としない錠剤、並びにドライエマルションおよびその製造方法 |
| JPH11189547A (ja) * | 1997-12-26 | 1999-07-13 | Taisho Pharmaceut Co Ltd | 安定化されたニコランジル製剤及びその製造方法 |
| ATE272395T1 (de) * | 1998-05-15 | 2004-08-15 | Chugai Pharmaceutical Co Ltd | Präparationen zur kontrollierten freisetzung |
| JP2001010950A (ja) * | 1999-06-29 | 2001-01-16 | Taiyo Yakuhin Kogyo Kk | 安定で良好な薬物放出を有する医薬組成物 |
-
2004
- 2004-07-08 FR FR0407590A patent/FR2872705B1/fr not_active Expired - Fee Related
-
2005
- 2005-07-05 JP JP2007519838A patent/JP2008505873A/ja active Pending
- 2005-07-05 EA EA200700191A patent/EA012967B1/ru not_active IP Right Cessation
- 2005-07-05 MX MXPA06015151A patent/MXPA06015151A/es active IP Right Grant
- 2005-07-05 AU AU2005271131A patent/AU2005271131B2/en not_active Ceased
- 2005-07-05 NZ NZ552983A patent/NZ552983A/en not_active IP Right Cessation
- 2005-07-05 CN CN200580022748A patent/CN100591356C/zh not_active Expired - Fee Related
- 2005-07-05 EP EP05786080A patent/EP1776093A1/fr not_active Withdrawn
- 2005-07-05 WO PCT/FR2005/001730 patent/WO2006016040A1/fr not_active Ceased
- 2005-07-05 ZA ZA200700704A patent/ZA200700704B/xx unknown
- 2005-07-05 BR BRPI0513005-0A patent/BRPI0513005A/pt not_active IP Right Cessation
- 2005-07-05 KR KR1020077000276A patent/KR20070030262A/ko not_active Ceased
- 2005-07-05 CA CA002570863A patent/CA2570863A1/fr not_active Abandoned
-
2006
- 2006-12-20 US US11/642,575 patent/US20070190134A1/en not_active Abandoned
- 2006-12-24 IL IL180285A patent/IL180285A0/en unknown
-
2007
- 2007-01-11 NO NO20070186A patent/NO20070186L/no not_active Application Discontinuation
- 2007-02-05 MA MA29654A patent/MA28783B1/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EA012967B1 (ru) | 2010-02-26 |
| MA28783B1 (fr) | 2007-08-01 |
| EA200700191A1 (ru) | 2007-06-29 |
| HK1107256A1 (zh) | 2008-04-03 |
| EP1776093A1 (fr) | 2007-04-25 |
| JP2008505873A (ja) | 2008-02-28 |
| US20070190134A1 (en) | 2007-08-16 |
| NZ552983A (en) | 2010-07-30 |
| AU2005271131A1 (en) | 2006-02-16 |
| ZA200700704B (en) | 2008-10-29 |
| IL180285A0 (en) | 2007-07-04 |
| NO20070186L (no) | 2007-01-31 |
| KR20070030262A (ko) | 2007-03-15 |
| CN1980644A (zh) | 2007-06-13 |
| CN100591356C (zh) | 2010-02-24 |
| FR2872705A1 (fr) | 2006-01-13 |
| AU2005271131B2 (en) | 2010-04-29 |
| CA2570863A1 (fr) | 2006-02-16 |
| FR2872705B1 (fr) | 2008-07-18 |
| MXPA06015151A (es) | 2007-03-26 |
| WO2006016040A1 (fr) | 2006-02-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 8A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2260 DE 29/04/2014. |