BRPI0516515A - composições contendo lipase, protease e amilase para o tratamento da insuficiência pancreática - Google Patents

composições contendo lipase, protease e amilase para o tratamento da insuficiência pancreática

Info

Publication number
BRPI0516515A
BRPI0516515A BRPI0516515-6A BRPI0516515A BRPI0516515A BR PI0516515 A BRPI0516515 A BR PI0516515A BR PI0516515 A BRPI0516515 A BR PI0516515A BR PI0516515 A BRPI0516515 A BR PI0516515A
Authority
BR
Brazil
Prior art keywords
pancreatic insufficiency
protease
treatment
lipase
compositions
Prior art date
Application number
BRPI0516515-6A
Other languages
English (en)
Inventor
Alexey L Margolin
Bhami C Shenoy
Frederick T Murray
Original Assignee
Altus Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altus Pharmaceuticals Inc filed Critical Altus Pharmaceuticals Inc
Publication of BRPI0516515A publication Critical patent/BRPI0516515A/pt
Publication of BRPI0516515B1 publication Critical patent/BRPI0516515B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/54—Mixtures of enzymes or proenzymes covered by more than a single one of groups A61K38/44 - A61K38/46 or A61K38/51 - A61K38/53
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

COMPOSIçõES CONTENDO LIPASE, PROTEASE E AMILASE PARA O TRATAMENTO DA INSUFICIêNCIA PANCREáTICA. A presente invenção refere-se às composições para o tratamento de condições, incluindo a insuficiência pancreática. As composições da presente invenção compreendem lipase, protease e amilase em uma relação particular que fornece resultados benéficos em pacientes, tais como aqueles afligidos com insuficiência pancreática. Esta invenção refere-se aos métodos que utilizam tais composições para o tratamento de insuficiência pancreática.
BRPI0516515-6A 2004-10-14 2005-10-14 Composição compreendendo lipase, protease e amilase e uso da mesma BRPI0516515B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US61876404P 2004-10-14 2004-10-14
US60/618,764 2004-10-14
PCT/US2005/036802 WO2006044529A1 (en) 2004-10-14 2005-10-14 Compositions containing lipase; protease and amylase for treating pancreatic insufficiency

Publications (2)

Publication Number Publication Date
BRPI0516515A true BRPI0516515A (pt) 2008-09-16
BRPI0516515B1 BRPI0516515B1 (pt) 2018-05-29

Family

ID=35840531

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0516515-6A BRPI0516515B1 (pt) 2004-10-14 2005-10-14 Composição compreendendo lipase, protease e amilase e uso da mesma

Country Status (23)

Country Link
US (1) US7718169B2 (pt)
EP (2) EP1809320B1 (pt)
JP (1) JP4908420B2 (pt)
KR (1) KR101333664B1 (pt)
CN (1) CN101068565B (pt)
AT (1) ATE474592T1 (pt)
AU (1) AU2005295754B2 (pt)
BR (1) BRPI0516515B1 (pt)
CA (1) CA2584069C (pt)
CY (2) CY1110838T1 (pt)
DE (1) DE602005022471D1 (pt)
DK (2) DK2198880T3 (pt)
ES (2) ES2614157T3 (pt)
HR (1) HRP20161684T1 (pt)
HU (1) HUE031245T2 (pt)
LT (1) LT2198880T (pt)
MX (1) MX2007004534A (pt)
PL (2) PL2198880T3 (pt)
PT (2) PT1809320E (pt)
RU (1) RU2385736C2 (pt)
SI (2) SI1809320T1 (pt)
UA (1) UA91521C2 (pt)
WO (1) WO2006044529A1 (pt)

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Also Published As

Publication number Publication date
CY1110838T1 (el) 2015-06-10
PL1809320T3 (pl) 2011-11-30
UA91521C2 (ru) 2010-08-10
EP2198880B1 (en) 2016-11-23
EP2198880A1 (en) 2010-06-23
ATE474592T1 (de) 2010-08-15
US7718169B2 (en) 2010-05-18
AU2005295754A2 (en) 2010-09-02
MX2007004534A (es) 2007-11-08
PT2198880T (pt) 2017-01-04
ES2614157T3 (es) 2017-05-29
JP2008516965A (ja) 2008-05-22
HUE031245T2 (en) 2017-06-28
CN101068565B (zh) 2010-11-17
DE602005022471D1 (de) 2010-09-02
AU2005295754A1 (en) 2006-04-27
EP1809320A1 (en) 2007-07-25
EP1809320B1 (en) 2010-07-21
JP4908420B2 (ja) 2012-04-04
KR101333664B1 (ko) 2013-11-28
BRPI0516515B1 (pt) 2018-05-29
AU2005295754B2 (en) 2010-09-09
CA2584069C (en) 2017-02-07
CN101068565A (zh) 2007-11-07
CA2584069A1 (en) 2006-04-27
CY1118597T1 (el) 2017-07-12
DK1809320T3 (da) 2010-11-15
RU2007117728A (ru) 2008-11-20
HRP20161684T1 (hr) 2017-02-24
SI2198880T1 (sl) 2017-02-28
SI1809320T1 (sl) 2010-11-30
US20060121017A1 (en) 2006-06-08
WO2006044529A1 (en) 2006-04-27
KR20070074622A (ko) 2007-07-12
PT1809320E (pt) 2010-10-25
HK1109068A1 (en) 2008-05-30
LT2198880T (lt) 2017-02-27
RU2385736C2 (ru) 2010-04-10
ES2352086T3 (es) 2011-02-15
DK2198880T3 (en) 2017-01-23
PL2198880T3 (pl) 2017-04-28

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