BRPI0517749A - dispositivo de aplicação para aplicar um dispositivo de micro-agulha a uma superfìcie de pele, e, método para usar um dispositivo de aplicação - Google Patents

dispositivo de aplicação para aplicar um dispositivo de micro-agulha a uma superfìcie de pele, e, método para usar um dispositivo de aplicação

Info

Publication number
BRPI0517749A
BRPI0517749A BRPI0517749-9A BRPI0517749A BRPI0517749A BR PI0517749 A BRPI0517749 A BR PI0517749A BR PI0517749 A BRPI0517749 A BR PI0517749A BR PI0517749 A BRPI0517749 A BR PI0517749A
Authority
BR
Brazil
Prior art keywords
application device
micro
applying
skin surface
needle
Prior art date
Application number
BRPI0517749-9A
Other languages
English (en)
Inventor
Adam S Cantor
Franklyn L Frederickson
Peter R Johnson
Ted K Ringsred
Original Assignee
3M Innovative Properties Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 3M Innovative Properties Co filed Critical 3M Innovative Properties Co
Publication of BRPI0517749A publication Critical patent/BRPI0517749A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Medical Informatics (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Micromachines (AREA)

Abstract

DISPOSITIVO DE APLICAçãO PARA APLICAR UM DISPOSITIVO DE MICRO-AGULHA A UMA SUPERFìCIE DE PELE, E, MéTODO PARA USAR UM DISPOSITIVO DE APLICAçãO. Um aplicador (100) usado para aplicar arranjos de micro-agulhas (10) a um mamífero. Em particular, um dispositivo de aplicação para aplicar um dispositivo de micro-agulha (120) a uma superficie da pele compreendendo uma lâmina flexível (110) tendo uma área central elevada (115) anexada ao dispositivo de micro-agulha e um membro de suporte na, ou, próximo à periferia da lâmina flexivel, onde a lâmina flexivel é configurada de modo que ela sofra um movimento escalonado na direção ortogonal ao plano principal da lâmina.
BRPI0517749-9A 2004-11-18 2005-11-18 dispositivo de aplicação para aplicar um dispositivo de micro-agulha a uma superfìcie de pele, e, método para usar um dispositivo de aplicação BRPI0517749A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62921504P 2004-11-18 2004-11-18
PCT/US2005/041854 WO2006055795A1 (en) 2004-11-18 2005-11-18 Low-profile microneedle array applicator

Publications (1)

Publication Number Publication Date
BRPI0517749A true BRPI0517749A (pt) 2008-10-21

Family

ID=35809616

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0517749-9A BRPI0517749A (pt) 2004-11-18 2005-11-18 dispositivo de aplicação para aplicar um dispositivo de micro-agulha a uma superfìcie de pele, e, método para usar um dispositivo de aplicação

Country Status (12)

Country Link
US (2) US8267889B2 (pt)
EP (1) EP1833547A1 (pt)
JP (2) JP2008520369A (pt)
KR (2) KR20070102669A (pt)
CN (1) CN101060883B (pt)
AU (1) AU2005306422A1 (pt)
BR (1) BRPI0517749A (pt)
CA (1) CA2587505C (pt)
IL (1) IL183204A (pt)
MX (1) MX2007005813A (pt)
WO (1) WO2006055795A1 (pt)
ZA (1) ZA200705102B (pt)

Families Citing this family (116)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7828827B2 (en) 2002-05-24 2010-11-09 Corium International, Inc. Method of exfoliation of skin using closely-packed microstructures
GB0402131D0 (en) 2004-01-30 2004-03-03 Isis Innovation Delivery method
AU2005228145B2 (en) * 2004-03-24 2011-03-03 Corium Pharma Solutions, Inc. Transdermal delivery device
KR20070102669A (ko) 2004-11-18 2007-10-19 쓰리엠 이노베이티브 프로퍼티즈 컴파니 로우-프로파일 미세 바늘 어레이 인가 장치
WO2006108185A1 (en) 2005-04-07 2006-10-12 3M Innovative Properties Company System and method for tool feedback sensing
WO2007002523A2 (en) * 2005-06-24 2007-01-04 3M Innovative Properties Company Collapsible patch with microneedle array
EP2258441A3 (en) * 2005-09-02 2011-09-21 Intercell USA, Inc. Devices for transcutaneous delivery of vaccines and transdermal delivery of drugs
US9119945B2 (en) * 2006-04-20 2015-09-01 3M Innovative Properties Company Device for applying a microneedle array
KR100886633B1 (ko) * 2006-07-14 2009-03-04 호남석유화학 주식회사 전면부에 피부를 통해 체내로 전달하고자 하는 물질의 수용공간을 갖는 피부 침투용 미세 돌기 장치
EP1884223A1 (en) † 2006-08-04 2008-02-06 IP Randwyck B.V. Wound-stimulating unit
JP5553612B2 (ja) * 2007-01-22 2014-07-16 コリウム インターナショナル, インコーポレイテッド マイクロニードルアレイ用アプリケータ
KR100893250B1 (ko) * 2007-02-28 2009-04-17 광주과학기술원 능동형 미세바늘 장치
JP4978245B2 (ja) * 2007-03-08 2012-07-18 凸版印刷株式会社 針状体、針状体製造方法および薬物輸送デバイス
GB2448493B (en) 2007-04-16 2009-10-14 Dewan Fazlul Hoque Chowdhury Microneedle transdermal delivery device
WO2008130587A2 (en) 2007-04-16 2008-10-30 Corium International, Inc. Solvent-cast microneedle arrays containing active
US8911749B2 (en) 2007-04-16 2014-12-16 Corium International, Inc. Vaccine delivery via microneedle arrays
JP5222512B2 (ja) * 2007-09-19 2013-06-26 凸版印刷株式会社 マイクロニードルチップ
JP5178132B2 (ja) * 2007-10-11 2013-04-10 キヤノン株式会社 画像処理システム並びに画像処理方法
KR101013581B1 (ko) * 2008-08-06 2011-02-14 라종주 전기 피부 미용기
US20110150946A1 (en) * 2008-08-22 2011-06-23 Al-Ghananeem Abeer M Transdermal Delivery of Apomorphine Using Microneedles
US8579862B2 (en) * 2009-02-23 2013-11-12 Medrx Co., Ltd. Applicator for microneedle array
JP5820805B2 (ja) * 2009-04-24 2015-11-24 コリウム インターナショナル, インコーポレイテッド マイクロプロジェクションのアレイの製造のためのプロセス
CN102695543B (zh) * 2009-08-07 2015-04-01 株式会社医药处方 花插座型微针的给药器装置
US8834423B2 (en) 2009-10-23 2014-09-16 University of Pittsburgh—of the Commonwealth System of Higher Education Dissolvable microneedle arrays for transdermal delivery to human skin
US20110172639A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Device and method for delivery of microneedle to desired depth within the skin
US20110172645A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Wearable drug delivery device including integrated pumping and activation elements
US20110172638A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Drug delivery device including multi-functional cover
USD619245S1 (en) 2010-01-08 2010-07-06 Ratio, Inc. Drug delivery device
US20110172609A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Microneedle component assembly for drug delivery device
USD638534S1 (en) 2010-01-08 2011-05-24 Ratio, Inc. Drug delivery device
US20110172637A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Drug delivery device including tissue support structure
JP5721142B2 (ja) * 2010-01-22 2015-05-20 株式会社 メドレックス マイクロニードル貼付剤の貼付補助具
WO2011105496A1 (ja) 2010-02-24 2011-09-01 久光製薬株式会社 マイクロニードルデバイス
JP6327852B2 (ja) 2010-05-04 2018-05-23 コリウム インターナショナル, インコーポレイテッド 微小突起アレイを使用した副甲状腺ホルモンの経皮送達のための方法及びデバイス
AU2011248166B2 (en) 2010-05-04 2015-12-17 Corium Pharma Solutions, Inc. Applicators for microneedles
WO2011141426A1 (en) 2010-05-10 2011-11-17 Tt Seed S.R.L. Needle device for detecting biosignals through the skin
US8668675B2 (en) 2010-11-03 2014-03-11 Flugen, Inc. Wearable drug delivery device having spring drive and sliding actuation mechanism
CN101972499B (zh) * 2010-11-10 2016-07-06 吉林大学 轻松无痛输药装置
IT1403293B1 (it) 2010-12-27 2013-10-17 Fond Don Carlo Gnocchi Onlus Apparecchiatura ad aghi per la somministrazione transdermica di farmaci.
JP5908977B2 (ja) 2011-06-14 2016-04-26 ジョンジュ ナ ラ−効果またはラプラス−効果による皮膚改善装置及び方法
JP6265740B2 (ja) 2011-10-06 2018-01-24 久光製薬株式会社 アプリケータ
AU2012323392A1 (en) * 2011-10-12 2014-04-24 3M Innovative Properties Company Integrated microneedle array delivery system
US11179553B2 (en) 2011-10-12 2021-11-23 Vaxxas Pty Limited Delivery device
AU2012323395B2 (en) * 2011-10-12 2015-10-01 Kindeva Drug Delivery L.P. Integrated microneedle array delivery system
US9011350B2 (en) 2011-11-30 2015-04-21 Lincoln Diagnostics, Inc. Allergy testing device and method of testing for allergies
US8469900B2 (en) * 2011-11-30 2013-06-25 Lincoln Diagnostics, Inc. Allergy testing device and method of testing for allergies
DE102011089723A1 (de) * 2011-12-23 2013-06-27 Robert Bosch Gmbh Mikronadelarray-Applikator und Verfahren zur Applikation eines Mikronadelarrays
EP4112112A1 (en) 2012-05-01 2023-01-04 University of Pittsburgh - Of the Commonwealth System of Higher Education Tip-loaded microneedle arrays for transdermal insertion
EP2852352B1 (en) 2012-05-04 2021-09-01 Roger Khouri Surgical tools
JP5593355B2 (ja) * 2012-07-23 2014-09-24 凸版印刷株式会社 針状体および針状体製造方法
WO2014059104A1 (en) 2012-10-10 2014-04-17 3M Innovative Properties Company Applicator and method for applying a microneedle device to skin
EP2906284B8 (en) 2012-10-10 2021-01-20 Kindeva Drug Delivery L.P. Force-controlled applicator for applying a microneedle device to skin
WO2014078545A1 (en) * 2012-11-16 2014-05-22 3M Innovative Properties Company Force-controlled applicator for applying a microneedle device to skin
CA2894718A1 (en) 2012-11-21 2014-05-30 Circuit Therapeutics, Inc. System and method for optogenetic therapy
RU2698095C2 (ru) 2012-12-21 2019-08-22 Кориум Интернэшнл, Инк. Микроматрица для доставки терапевтического средства и способы использования
BR122020006959B1 (pt) 2013-03-12 2022-04-26 Corium, Inc Aplicador de microprojeções
AU2014233695A1 (en) 2013-03-15 2015-10-01 Corium International, Inc. Microarray for delivery of therapeutic agent and methods of use
WO2014144973A1 (en) 2013-03-15 2014-09-18 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
WO2014150285A2 (en) 2013-03-15 2014-09-25 Corium International, Inc. Multiple impact microprojection applicators and methods of use
US10384045B2 (en) 2013-03-15 2019-08-20 Corium, Inc. Microarray with polymer-free microstructures, methods of making, and methods of use
WO2015017561A1 (en) 2013-07-30 2015-02-05 Zosano Pharma, Inc. Low-profile microneedle patch applicator
DK3052181T3 (da) 2013-09-30 2022-10-24 Georgia Tech Res Inst Mikronåleplastre og systemer
EP3097943A4 (en) * 2014-01-24 2017-09-13 Toppan Printing Co., Ltd. Microneedle unit
CN105916543B (zh) * 2014-01-24 2020-06-30 凸版印刷株式会社 微针单元以及微针组件
WO2015119906A1 (en) 2014-02-05 2015-08-13 Amgen Inc. Drug delivery system with electromagnetic field generator
USD763504S1 (en) 2014-04-02 2016-08-09 Hisamitsu Pharmaceutical Co., Inc. Cosmetic pack sheet
WO2015164840A1 (en) 2014-04-24 2015-10-29 Georgia Tech Research Corporation Microneedles and methods of manufacture thereof
EP3188714A1 (en) 2014-09-04 2017-07-12 Corium International, Inc. Microstructure array, methods of making, and methods of use
EP3251721B1 (en) * 2015-01-27 2019-12-18 Toppan Printing Co., Ltd. Transdermal administration device
EP4218892A1 (en) * 2015-02-02 2023-08-02 Vaxxas Pty Limited Microprojection array applicator
US11116953B2 (en) * 2015-02-13 2021-09-14 Medrx Co., Ltd. Microneedle applicator and microneedle patch application device
WO2016149673A1 (en) 2015-03-18 2016-09-22 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Bioactive components conjugated to substrates of microneedle arrays
WO2017004067A1 (en) 2015-06-29 2017-01-05 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
KR102135518B1 (ko) 2015-09-02 2020-07-17 히사미쓰 세이야꾸 가부시키가이샤 어플리케이터
WO2017045031A1 (en) 2015-09-18 2017-03-23 Vaxxas Pty Limited Microprojection arrays with microprojections having large surface area profiles
AU2016333148B2 (en) 2015-09-28 2021-10-14 Vaxxas Pty Limited Microprojection arrays with enhanced skin penetrating properties and methods thereof
KR101757866B1 (ko) * 2015-10-08 2017-07-14 주식회사 라파스 마이크로니들패치 포장케이스
US11684763B2 (en) 2015-10-16 2023-06-27 University of Pittsburgh—of the Commonwealth System of Higher Education Multi-component bio-active drug delivery and controlled release to the skin by microneedle array devices
EP3738642A1 (en) 2015-12-21 2020-11-18 MEDRx Co., Ltd. Microneedle patch applicator
US11744889B2 (en) 2016-01-05 2023-09-05 University of Pittsburgh—of the Commonwealth System of Higher Education Skin microenvironment targeted delivery for promoting immune and other responses
US10500351B2 (en) * 2016-02-12 2019-12-10 Shawn Michael Michels Aid for subcutaneous tissue injection and process of effecting the injection with the aid
KR102590629B1 (ko) 2016-12-16 2023-10-19 소렌토 쎄라퓨틱스, 인코포레이티드 유체 전달 장치용 어플리케이션 디바이스 및 그 이용 방법
KR101745445B1 (ko) * 2017-01-25 2017-06-09 송득영 가압형 약물 주입 시스템
EP4306803B1 (en) 2017-03-31 2026-05-06 Vaxxas Pty Limited Device and method for coating surfaces
JP2018191783A (ja) * 2017-05-15 2018-12-06 富士フイルム株式会社 マイクロニードルアレイユニット、および容器
JP2018192177A (ja) * 2017-05-22 2018-12-06 コスメディ製薬株式会社 水溶性化粧用シート保持フィルム
US11175128B2 (en) 2017-06-13 2021-11-16 Vaxxas Pty Limited Quality control of substrate coatings
AU2018309562A1 (en) * 2017-08-04 2020-02-20 Vaxxas Pty Limited Compact high mechanical energy storage and low trigger force actuator for the delivery of microprojection array patches (MAP)
KR20190027233A (ko) * 2017-09-06 2019-03-14 주식회사 라파스 마이크로니들 보호 성능이 개선된 마이크로니들 패치 및 이러한 마이크로니들 패치와 어플리케이터로 구성되는 마이크로니들 패치 어플리케이터 시스템
US10786203B1 (en) * 2018-01-30 2020-09-29 Daniel M. Besser Medical patch applicator device
WO2019166572A1 (en) 2018-02-28 2019-09-06 Pharming Intellectual Property B.V. Pharmaceutical system for transdermal administration of a c1 -esterase inhibitor
US20210008360A1 (en) * 2018-03-13 2021-01-14 Medrx Co., Ltd. Adhesion Member and Microneedle Patch
CN108671385A (zh) * 2018-06-21 2018-10-19 陈宏� 一种穴位自动贴敷直压微针及使用方法
JP1632957S (pt) 2018-10-30 2019-06-03
WO2020090845A1 (ja) * 2018-10-31 2020-05-07 富士フイルム株式会社 マイクロニードルアレイデバイス
EP3903856A4 (en) * 2018-12-25 2022-09-14 Hirosaki University DRUG ADMINISTRATION DEVICE AND SYSTEM
DE102019200557A1 (de) * 2019-01-17 2020-07-23 Lts Lohmann Therapie-Systeme Ag Applikator
JP2022532215A (ja) 2019-05-16 2022-07-13 ユニバーシティ オブ ピッツバーグ - オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション 皮膚および非皮膚薬物送達のためのアンダーカット特徴を有するマイクロニードルアレイ
CN114761054B (zh) 2019-10-22 2025-07-15 佐治亚科技研究公司 利用浇铸制剂中的组分溶解度的调整来制作微针的方法
JPWO2021251464A1 (pt) * 2020-06-12 2021-12-16
US11389376B2 (en) 2020-12-21 2022-07-19 Mediccene Inc. Wearable intravenous fluid delivery system
US12611530B2 (en) 2020-12-21 2026-04-28 Mediccene Inc. Intradermal drug delivery device
US12214346B2 (en) 2021-10-13 2025-02-04 Satio, Inc. Dermal patch with a diagnostic test strip
US11964121B2 (en) 2021-10-13 2024-04-23 Satio, Inc. Mono dose dermal patch for pharmaceutical delivery
US11877848B2 (en) 2021-11-08 2024-01-23 Satio, Inc. Dermal patch for collecting a physiological sample
US12048543B2 (en) 2021-11-08 2024-07-30 Satio, Inc. Dermal patch for collecting a physiological sample with removable vial
US12053284B2 (en) 2021-11-08 2024-08-06 Satio, Inc. Dermal patch for collecting a physiological sample
US12029562B2 (en) 2021-04-14 2024-07-09 Satio, Inc. Dermal patch system
US12023156B2 (en) 2021-10-13 2024-07-02 Satio, Inc. Dermal patch for collecting a physiological sample
US12178979B2 (en) 2021-10-13 2024-12-31 Satio, Inc. Dermal patch for delivering a pharmaceutical
US11672965B2 (en) 2021-09-28 2023-06-13 Biolinq Incorporated Microneedle enclosure and applicator device for microneedle array based continuous analyte monitoring device
USD1033641S1 (en) 2021-12-17 2024-07-02 Biolinq Incorporated Microneedle array sensor applicator device
KR102764041B1 (ko) * 2022-04-14 2025-02-07 주식회사 에스엔비아 마이크로니들 어플리케이터
USD1057153S1 (en) 2022-04-29 2025-01-07 Biolinq Incorporated Microneedle array sensor applicator device
EP4587094A2 (en) * 2022-09-13 2025-07-23 Micron Biomedical, Inc. Microneedle patch with force-feedback indicator
USD1085416S1 (en) * 2023-10-27 2025-07-22 Guangzhou Ekai Electronic Technology Co., Ltd. Skincare microneedling device for beauty machine

Family Cites Families (127)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE25637E (en) 1964-09-08 Means for vaccinating
US3123212A (en) 1964-03-03 Multiple disposable intracutaneous injector package
US3072122A (en) 1959-01-15 1963-01-08 Rosenthal Sol Roy Package for transcutaneous injection
US3034507A (en) 1960-05-10 1962-05-15 American Cyanamid Co Intracutaneous injection device
US3136314A (en) 1960-08-01 1964-06-09 Kravitz Harvey Vaccinating devices
US3246647A (en) 1962-07-23 1966-04-19 American Cyanamid Co Disposable intracutaneous injector
US3221740A (en) 1962-08-31 1965-12-07 Rosenthal Sol Roy Injection device
GB1080986A (en) 1964-09-02 1967-08-31 Allen And Hanburys Surgical En Multiple puncture apparatus
US3322121A (en) 1965-11-26 1967-05-30 Oscar H Banker Skin-puncturing unit with a collapsible protective cover
US3510933A (en) 1967-05-26 1970-05-12 American Cyanamid Co Apparatus and method for continuously forming intracutaneous injectors
US3466131A (en) 1967-09-07 1969-09-09 Becton Dickinson Co Dispensing applicator package
US3512520A (en) 1967-11-01 1970-05-19 Michael N Cowan Antigenic test applicator
US3596660A (en) 1969-05-12 1971-08-03 Illinois Tool Works Injection device
US3675766A (en) 1970-02-04 1972-07-11 Sol Roy Rosenthal Multiple puncture injector device
US3688764A (en) 1970-08-20 1972-09-05 Bard Hamilton Co Inc Intracutaneous injection system
US3964482A (en) 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
US3678150A (en) 1971-07-27 1972-07-18 American Cyanamid Co Process for improving the stability of ppd, qt and histoplasmin on tine applicators
DE2250293A1 (de) 1972-10-13 1974-04-25 Bayern Freistaat Impfstempel zur cutanen pockenimpfung mittels trockenimpfstoff
OA05448A (fr) 1975-10-16 1981-03-31 Manufrance Manufacture Francai Dispositif vaccinateur multipénétrant.
US4304241A (en) 1978-09-05 1981-12-08 Aller-Screen, Inc. Skin testing device
US4237906A (en) 1978-12-06 1980-12-09 Havstad Harold R Antigen injection assembly
GB2064329B (en) 1979-11-01 1983-06-22 Matburn Holdings Ltd Multiple puncture apparatus
FR2474856A1 (fr) 1980-01-31 1981-08-07 Merieux Inst Dispositif scarificateur
US4360016A (en) 1980-07-01 1982-11-23 Transidyne General Corp. Blood collecting device
US4503856A (en) 1981-06-29 1985-03-12 Sherwood Medical Company Lancet injector
US4517978A (en) 1983-01-13 1985-05-21 Levin Paul D Blood sampling instrument
US4474751A (en) 1983-05-16 1984-10-02 Merck & Co., Inc. Ophthalmic drug delivery system utilizing thermosetting gels
US4627445A (en) 1985-04-08 1986-12-09 Garid, Inc. Glucose medical monitoring system
GB8710470D0 (en) 1987-05-01 1987-06-03 Mumford Ltd Owen Blood sampling devices
US4850973A (en) 1987-10-16 1989-07-25 Pavel Jordon & Associates Plastic device for injection and obtaining blood samples
US5192535A (en) 1988-02-08 1993-03-09 Insite Vision Incorporated Ophthalmic suspensions
GB2221394B (en) 1988-08-05 1992-03-04 Eilert Eilertsen An injection device
US4924879A (en) 1988-10-07 1990-05-15 Brien Walter J O Blood lancet device
US4920977A (en) 1988-10-25 1990-05-01 Becton, Dickinson And Company Blood collection assembly with lancet and microcollection tube
EP0429842B1 (en) 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Device for the transdermal administration of protein or peptide drug
US5402798A (en) * 1991-07-18 1995-04-04 Swierczek; Remi Disposable skin perforator and blood testing device
DE4212315A1 (de) 1992-04-13 1993-10-14 Boehringer Mannheim Gmbh Blutlanzettenvorrichtung zur Entnahme von Blut für Diagnosezwecke
DE4212723C1 (de) 1992-04-16 1993-11-04 Arta Plast Ab Tyresoe Lanzettenvorrichtung zum punktieren der haut
US5340572A (en) 1993-02-08 1994-08-23 Insite Vision Incorporated Alkaline ophthalmic suspensions
JP2630197B2 (ja) 1993-04-28 1997-07-16 株式会社ニッショー 血液吸出器具
DE19518932C2 (de) 1994-05-23 1999-03-18 Samsung Electro Mech Vorrichtung zur Perforation der Haut für die Vorbereitung einer transdermalen Medikation
US5487726A (en) 1994-06-16 1996-01-30 Ryder International Corporation Vaccine applicator system
US5636640A (en) * 1995-02-06 1997-06-10 Volunteers For Medical Engineering Liquid sampling and test apparatus
AU5869796A (en) 1995-05-22 1996-12-11 Ned A. Godshall Micromechanical patch for enhancing the delivery of compound s through the skin
WO1996037155A1 (en) 1995-05-22 1996-11-28 Silicon Microdevices, Inc. Micromechanical device and method for enhancing delivery of compounds through the skin
DE19525607A1 (de) 1995-07-14 1997-01-16 Boehringer Ingelheim Kg Transcorneales Arzneimittelfreigabesystem
ATE234129T1 (de) 1996-06-18 2003-03-15 Alza Corp Vorrichtung zur verbesserung der transdermalen verabreichung von medikamenten oder der abnahme von körperflüssigkeiten
JP4054381B2 (ja) 1996-09-17 2008-02-27 デカ・プロダクツ・リミテッド・パートナーシップ 移送による薬伝達システム
US6797276B1 (en) 1996-11-14 2004-09-28 The United States Of America As Represented By The Secretary Of The Army Use of penetration enhancers and barrier disruption agents to enhance the transcutaneous immune response
US5968633A (en) * 1997-06-06 1999-10-19 The Procter & Gamble Company Selectively-activatible sheet material for dispensing and dispersing a substance onto a target surface
CN1161164C (zh) 1997-12-11 2004-08-11 阿尔扎有限公司 用于通过体表导入或提取质剂的装置
DK1037687T3 (da) 1997-12-11 2009-01-26 Alza Corp Anordning til at forbedre et middels transdermale strömning
JP4647098B2 (ja) 1997-12-31 2011-03-09 メドトロニック ミニメド インコーポレイテッド 挿入セットのための挿入装置
US6091975A (en) 1998-04-01 2000-07-18 Alza Corporation Minimally invasive detecting device
CA2229522A1 (en) * 1998-04-15 1999-10-15 Thomas Randall Inkpen Needle aid
US6503231B1 (en) 1998-06-10 2003-01-07 Georgia Tech Research Corporation Microneedle device for transport of molecules across tissue
AU767122B2 (en) 1998-06-10 2003-10-30 Georgia Tech Research Corporation Microneedle devices and methods of manufacture and use thereof
GB9817662D0 (en) 1998-08-13 1998-10-07 Crocker Peter J Substance delivery
DE69921489T2 (de) 1998-08-31 2005-10-27 Johnson & Johnson Consumer Companies, Inc. Elektrotransportvorrichtung mit klingen
US6022368A (en) * 1998-11-30 2000-02-08 Gavronsky; Stas Acupuncture method and device
US6713291B2 (en) 1999-01-28 2004-03-30 Alan D. King Electrodes coated with treating agent and uses thereof
WO2000044438A1 (en) 1999-01-28 2000-08-03 Cyto Pulse Sciences, Inc. Delivery of macromolecules into cells
US6611707B1 (en) * 1999-06-04 2003-08-26 Georgia Tech Research Corporation Microneedle drug delivery device
US6743211B1 (en) 1999-11-23 2004-06-01 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
AU2005200910B2 (en) 1999-06-04 2006-08-03 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
US6256533B1 (en) 1999-06-09 2001-07-03 The Procter & Gamble Company Apparatus and method for using an intracutaneous microneedle array
US6312612B1 (en) 1999-06-09 2001-11-06 The Procter & Gamble Company Apparatus and method for manufacturing an intracutaneous microneedle array
US6379324B1 (en) 1999-06-09 2002-04-30 The Procter & Gamble Company Intracutaneous microneedle array apparatus
US6623457B1 (en) 1999-09-22 2003-09-23 Becton, Dickinson And Company Method and apparatus for the transdermal administration of a substance
US6835184B1 (en) 1999-09-24 2004-12-28 Becton, Dickinson And Company Method and device for abrading skin
US20020095134A1 (en) 1999-10-14 2002-07-18 Pettis Ronald J. Method for altering drug pharmacokinetics based on medical delivery platform
ATE295200T1 (de) 1999-12-10 2005-05-15 Alza Corp Hautbehandlungsvorrichtung zur verlängerten transdermalen verabreichung von medikamenten
DE60024312T2 (de) 1999-12-10 2006-08-17 Alza Corp., Mountain View Transdermale Wirkstoffabgabe von makromolekularen Wirkstoffen und Vorrichtung hierfür
US6881538B1 (en) 2000-03-05 2005-04-19 3M Innovative Properties Company Array comprising diamond-like glass film
US6595947B1 (en) 2000-05-22 2003-07-22 Becton, Dickinson And Company Topical delivery of vaccines
US7473244B2 (en) 2000-06-02 2009-01-06 The University Of Utah Research Foundation Active needle devices with integrated functionality
US6537242B1 (en) * 2000-06-06 2003-03-25 Becton, Dickinson And Company Method and apparatus for enhancing penetration of a member for the intradermal sampling or administration of a substance
US6589202B1 (en) 2000-06-29 2003-07-08 Becton Dickinson And Company Method and apparatus for transdermally sampling or administering a substance to a patient
US6440096B1 (en) 2000-07-14 2002-08-27 Becton, Dickinson And Co. Microdevice and method of manufacturing a microdevice
US6656147B1 (en) * 2000-07-17 2003-12-02 Becton, Dickinson And Company Method and delivery device for the transdermal administration of a substance
GB0017999D0 (en) 2000-07-21 2000-09-13 Smithkline Beecham Biolog Novel device
US7419481B2 (en) 2000-10-13 2008-09-02 Alza Corporation Apparatus and method for piercing skin with microprotrusions
EP1341442B1 (en) 2000-10-13 2005-06-29 Alza Corporation Microblade array impact applicator
AU2001296828B2 (en) 2000-10-13 2005-11-24 Alza Corporation Apparatus and method for piercing skin with microprotrusions
ES2317940T3 (es) 2000-10-13 2009-05-01 Alza Corporation Dispositivo de retencion para un elemento de microsalientes para aplicador de impactos.
US7131987B2 (en) 2000-10-16 2006-11-07 Corium International, Inc. Microstructures and method for treating and conditioning skin which cause less irritation during exfoliation
CA2427381A1 (en) 2000-10-26 2002-11-28 Alza Corporation Transdermal drug delivery devices having coated microprotrusions
AU2002237703A1 (en) 2000-11-09 2002-06-18 Biovalve Technologies, Inc. Microneedle adapter
WO2002055128A2 (en) 2000-11-30 2002-07-18 Biovalve Technologies Inc Fluid delivery and measurement systems and methods
US9302903B2 (en) 2000-12-14 2016-04-05 Georgia Tech Research Corporation Microneedle devices and production thereof
NZ529029A (en) 2001-04-20 2005-07-29 Alza Corp Microprojection array having a beneficial agent containing coating
US20020193729A1 (en) 2001-04-20 2002-12-19 Cormier Michel J.N. Microprojection array immunization patch and method
US6591124B2 (en) 2001-05-11 2003-07-08 The Procter & Gamble Company Portable interstitial fluid monitoring system
ES2268050T3 (es) 2001-06-08 2007-03-16 Becton, Dickinson And Company Dispositivo para manipular un conjunto de agujas o abrasion.
CN1253220C (zh) 2001-06-29 2006-04-26 贝克顿迪肯森公司 通过微管在真皮内输入疫苗和基因治疗剂
US6881203B2 (en) 2001-09-05 2005-04-19 3M Innovative Properties Company Microneedle arrays and methods of manufacturing the same
JP4383168B2 (ja) 2001-09-12 2009-12-16 ベクトン・ディキンソン・アンド・カンパニー マイクロ針投与デバイスおよび薬物投与デバイス
ATE498418T1 (de) 2001-09-21 2011-03-15 Valeritas Inc Durch gasdruck betätigte mikronadel-anordnungen und damit zusammenhängende systeme und verfahren
US6830562B2 (en) 2001-09-27 2004-12-14 Unomedical A/S Injector device for placing a subcutaneous infusion set
US7429258B2 (en) 2001-10-26 2008-09-30 Massachusetts Institute Of Technology Microneedle transport device
US6908453B2 (en) 2002-01-15 2005-06-21 3M Innovative Properties Company Microneedle devices and methods of manufacture
US7004928B2 (en) 2002-02-08 2006-02-28 Rosedale Medical, Inc. Autonomous, ambulatory analyte monitor or drug delivery device
US7858112B2 (en) 2002-02-28 2010-12-28 Lintec Corporation Percutaneous absorption system and percutaneous absorption method
JP4608187B2 (ja) * 2002-02-28 2011-01-05 リンテック株式会社 経皮吸収型製剤
US6780171B2 (en) 2002-04-02 2004-08-24 Becton, Dickinson And Company Intradermal delivery device
KR100993477B1 (ko) * 2002-06-25 2010-11-11 권성윤 약물 송달 및 다른 용도를 위한 신속 용해형마이크로-퍼포레이터
WO2004009172A1 (en) * 2002-07-19 2004-01-29 3M Innovative Properties Company Microneedle devices and microneedle delivery apparatus
CA2493728C (en) 2002-07-22 2013-10-29 Becton, Dickinson And Company Patch-like infusion device
AU2003268206B2 (en) 2002-08-29 2008-12-18 Becton, Dickinson And Company Microprotrusion arrays and methods for using same to deliver substances into tissue
US20050137525A1 (en) 2003-06-04 2005-06-23 Georgia Tech Research Corporation Drilling microneedle device
JP2007521092A (ja) 2003-07-02 2007-08-02 アルザ・コーポレーシヨン 小突起アレイの免疫化パッチおよび方法
EP2609948B1 (en) 2003-08-12 2020-01-08 Becton, Dickinson and Company Patch-like infusion device
US8353861B2 (en) 2003-09-18 2013-01-15 Texmac, Inc. Applicator for applying functional substances into human skin
KR20060108682A (ko) 2003-10-24 2006-10-18 알자 코포레이션 경피 약물 전달을 증대시키기 위한 전처리 방법 및 장치
AU2004287412A1 (en) 2003-10-28 2005-05-19 Alza Corporation Method and apparatus for reducing the incidence of tobacco use
US7097631B2 (en) 2003-10-31 2006-08-29 Alza Corporation Self-actuating applicator for microprojection array
US20050228313A1 (en) 2003-12-04 2005-10-13 University Technologies International Inc. Fluid sampling, analysis and delivery system
KR20060113730A (ko) * 2003-12-18 2006-11-02 노보 노르디스크 에이/에스 피부 스트레칭 수단을 가진 노즐 장치
US20070073220A1 (en) 2004-10-06 2007-03-29 Philip Bunce Inoculation device
US8057842B2 (en) 2004-11-18 2011-11-15 3M Innovative Properties Company Method of contact coating a microneedle array
KR20070102669A (ko) 2004-11-18 2007-10-19 쓰리엠 이노베이티브 프로퍼티즈 컴파니 로우-프로파일 미세 바늘 어레이 인가 장치
ATE468961T1 (de) 2004-12-07 2010-06-15 3M Innovative Properties Co Verfahren zum formen einer mikronadel
WO2007002523A2 (en) 2005-06-24 2007-01-04 3M Innovative Properties Company Collapsible patch with microneedle array
CA2613111C (en) 2005-06-27 2015-05-26 3M Innovative Properties Company Microneedle array applicator device and method of array application
US7658728B2 (en) 2006-01-10 2010-02-09 Yuzhakov Vadim V Microneedle array, patch, and applicator for transdermal drug delivery
US9119945B2 (en) 2006-04-20 2015-09-01 3M Innovative Properties Company Device for applying a microneedle array
US8668675B2 (en) 2010-11-03 2014-03-11 Flugen, Inc. Wearable drug delivery device having spring drive and sliding actuation mechanism

Also Published As

Publication number Publication date
KR20070102669A (ko) 2007-10-19
IL183204A (en) 2013-07-31
CN101060883A (zh) 2007-10-24
CN101060883B (zh) 2010-06-23
JP2008520369A (ja) 2008-06-19
CA2587505A1 (en) 2006-05-26
AU2005306422A1 (en) 2006-05-26
US20080114298A1 (en) 2008-05-15
MX2007005813A (es) 2007-07-18
WO2006055795A1 (en) 2006-05-26
CA2587505C (en) 2013-01-08
US8267889B2 (en) 2012-09-18
EP1833547A1 (en) 2007-09-19
KR20130026511A (ko) 2013-03-13
ZA200705102B (en) 2008-10-29
JP5587946B2 (ja) 2014-09-10
US8758298B2 (en) 2014-06-24
JP2012183358A (ja) 2012-09-27
IL183204A0 (en) 2007-08-19
US20130006219A1 (en) 2013-01-03

Similar Documents

Publication Publication Date Title
BRPI0820581A8 (pt) Dispositivo de interface com paciente, e, cânula nasal
AR044963A1 (es) Aparato y metodo para recubrir microproyecciones de perforacion de la piel
DE60111771D1 (de) Mikroklingeanordungsaufprallapplikator
BRPI0314854B8 (pt) cateter balão, processo para seu revestimento, e uso de uma solução.
ATE543441T1 (de) Nahtfreisetzung
BRPI0415629A (pt) aplicador auto-atuador para conjunto de microprojeções
BR0312671A (pt) Dispositivo de microagulhas, método para utilizar um dispositivo de microagulhas, e, método para aplicar um dispositivo de microagulhas
BRPI0416822A (pt) método e sistema de liberação de vacina transdérmica com ultra-som
ATE439085T1 (de) Expressionsvorrichtung mit geteilter spitze
ATE443505T1 (de) Massagevorrichtung
DE502007005362D1 (de) Biegeweiche vorrichtung zum einbringen einer medizinischen vorrichtung in den körper
BR112017019698A2 (pt) método para afixar uma placa-base de adesivo de um dispositivo de ostomia a uma superfície de pele de um usuário, e, kit de partes
BRPI0410295A (pt) método, aparelho e composição para tratamento da acne
BRPI0313214A2 (pt) dispositivo e procedimento para a medida da elasticidade de um órgão humano ou animal
BR0002192A (pt) Aplicador para aplicação de um produto e utilização de um aplicador
BRPI0517501A (pt) dispositivo médico apropriado para uso na administração de um componente ativo na ou através da pele
BR112015029865B8 (pt) Aparelho para injeção com microagulhas compreendendo um atuador invertido
BR112018005587A8 (pt) Métodos para aprimorar a aplicação tópica de um agente de benefício básico
BR0212963A (pt) Microdispositivo e método de fornecer ou retirar uma substância através da pele de um animal
BR0202111A (pt) Dispositivo para a aplicação de um produto de bronzeamento artificial sobre a pele, kit e processo de fabricação de um tal dispositivo
BRPI0602604A (pt) aparelho útil para posicionar um dispositivo em um endoscópio
BRPI0519882A2 (pt) cabo de aparelho e aparelho para barbear
BRPI0518181A (pt) dispositivo e método de aplicação de fluido
BRPI0508678A (pt) emplastro para provisão de terapia a um indivìduo, método para provisão de terapia a um indivìduo e método de fabricação de um emplatro que provê terapia a um indivìduo
BRPI0415986A (pt) método e aparelho para reduzir a incidência do uso de tabaco

Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.