BRPI0606685A2 - anticorpos gitr para o diagnóstico de nsclc - Google Patents

anticorpos gitr para o diagnóstico de nsclc

Info

Publication number
BRPI0606685A2
BRPI0606685A2 BRPI0606685-2A BRPI0606685A BRPI0606685A2 BR PI0606685 A2 BRPI0606685 A2 BR PI0606685A2 BR PI0606685 A BRPI0606685 A BR PI0606685A BR PI0606685 A2 BRPI0606685 A2 BR PI0606685A2
Authority
BR
Brazil
Prior art keywords
nsclc
diagnosis
gitr antibodies
gitr
antibodies
Prior art date
Application number
BRPI0606685-2A
Other languages
English (en)
Inventor
Beverly Teicher
Shrinivas Shankara
Bruce Roberts
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of BRPI0606685A2 publication Critical patent/BRPI0606685A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

ANTICORPOS GITR PARA O DIAGNóSTICO DE NSCLC. A presente invenção fornece métodos e composições para detectar, diagnosticar, prognosticar e monitorar o progresso de cânceres, por ex., NSCLC de origem epitelial, por ex., cânceres de pulmão, ovário,
BRPI0606685-2A 2005-01-19 2006-01-19 anticorpos gitr para o diagnóstico de nsclc BRPI0606685A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64534905P 2005-01-19 2005-01-19
PCT/US2006/002050 WO2006078911A2 (en) 2005-01-19 2006-01-19 Gitr antibodies for the diagnosis of nsclc

Publications (1)

Publication Number Publication Date
BRPI0606685A2 true BRPI0606685A2 (pt) 2009-07-14

Family

ID=36692925

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0606685-2A BRPI0606685A2 (pt) 2005-01-19 2006-01-19 anticorpos gitr para o diagnóstico de nsclc

Country Status (8)

Country Link
EP (1) EP1856281A2 (pt)
JP (1) JP2008527998A (pt)
CN (1) CN101133167A (pt)
AU (1) AU2006206343A1 (pt)
BR (1) BRPI0606685A2 (pt)
CA (1) CA2592330A1 (pt)
IL (1) IL184343A0 (pt)
WO (1) WO2006078911A2 (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2006230099B2 (en) 2005-03-25 2012-04-19 Gitr, Inc. GITR binding molecules and uses therefor
CN101801413A (zh) 2007-07-12 2010-08-11 托勒克斯股份有限公司 采用gitr结合分子的联合疗法
PT3023438T (pt) 2009-09-03 2020-05-08 Merck Sharp & Dohme Anticorpos anti-gitr
KR101549637B1 (ko) 2012-06-08 2015-09-03 국립암센터 신규한 Ｔｈ1 세포 전환용 에피토프 및 이의 용도
TW201605896A (zh) 2013-08-30 2016-02-16 安美基股份有限公司 Gitr抗原結合蛋白
AU2015271709B2 (en) 2014-06-06 2020-11-26 Bristol-Myers Squibb Company Antibodies against glucocorticoid-induced tumor necrosis factor receptor (GITR) and uses thereof
JP5995207B2 (ja) * 2014-11-28 2016-09-21 学校法人 学習院 含ホウ素ポルフィリン誘導体
JP6812364B2 (ja) * 2015-06-03 2021-01-13 ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ 癌診断用抗ｇｉｔｒ抗体
CA3005855A1 (en) 2015-11-19 2017-05-26 Bristol-Myers Squibb Company Antibodies against glucocorticoid-induced tumor necrosis factor receptor (gitr) and uses thereof
AU2017229575A1 (en) * 2016-03-08 2018-09-27 Janssen Biotech, Inc. GITR antibodies, methods, and uses
CN110382696B (zh) * 2017-03-07 2024-04-19 豪夫迈·罗氏有限公司 发现替代性抗原特异性抗体变体的方法
CN110869392A (zh) 2017-05-16 2020-03-06 百时美施贵宝公司 用抗gitr激动性抗体治疗癌症
CN109777872B (zh) * 2017-11-15 2021-04-02 北京大学 肺癌中的t细胞亚群及其特征基因

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6689607B2 (en) * 1997-10-21 2004-02-10 Human Genome Sciences, Inc. Human tumor, necrosis factor receptor-like proteins TR11, TR11SV1 and TR11SV2
US6503184B1 (en) * 1997-10-21 2003-01-07 Human Genome Sciences, Inc. Human tumor necrosis factor receptor-like proteins TR11, TR11SV1 and TR11SV2
WO1999020758A1 (en) * 1997-10-21 1999-04-29 Human Genome Sciences, Inc. Human tumor necrosis factor receptor-like proteins tr11, tr11sv1, and tr11sv2
US20030138426A1 (en) * 1997-10-21 2003-07-24 Human Genome Sciences, Inc. Human tumor necrosis factor receptor-like proteins TR11, TR11SV1, and TR11SV2
AU3860100A (en) * 1999-02-24 2000-09-14 Human Genome Sciences, Inc. Human tumor necrosis factor receptor-like proteins tr11, tr11sv1, and tr11sv2
WO2004108899A2 (en) * 2003-06-04 2004-12-16 The Government Of The United States As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention Pni microarray and uses

Also Published As

Publication number Publication date
WO2006078911A2 (en) 2006-07-27
AU2006206343A1 (en) 2006-07-27
CA2592330A1 (en) 2006-07-27
JP2008527998A (ja) 2008-07-31
CN101133167A (zh) 2008-02-27
EP1856281A2 (en) 2007-11-21
IL184343A0 (en) 2007-10-31
WO2006078911A3 (en) 2007-06-28

Similar Documents

Publication Publication Date Title
MX355416B (es) Biomarcadores de cancer de pulmon y usos de los mismos.
WO2008097908A3 (en) Methods of diagnosing and prognosing lung cancer
WO2006089125A3 (en) Methods of detecting ovarian cancer
BRPI0720361A2 (pt) Método para medir aglutinação de uma ou mais partículas em um ensaio de aglutinação induzida por alvo efetuado em uma câmara de reação, e, kit e dispositivo para medir um ou mais parâmetros de aglutinação de partículas em um ensaio de aglutinação induzida por alvo
WO2009037572A3 (en) Biomarker combinations for colorectal cancer
EP1869462A4 (en) Biomarkers for ovarian cancer and endometrial cancer: hepcidin
GB2451042A (en) Reagents and methods for using human embryonic stem cells to evaluate toxicity of pharmaceutical compounds and other chemicals
WO2009029550A3 (en) Highly sensitive system and methods for analysis of prostate specific antigen (psa)
WO2007114947A3 (en) Highly sensitive system and methods for analysis of troponin
BRPI0906903B8 (pt) anticorpo monoclonal e método de detecção da expressão de cd70
CR20190574A (es) Ensayos de diagnóstico para detectar, cuantificar y/o rastrear microbios y otros analitos
EP3054299A3 (en) Biomarkers for the early detection of breast cancer
ATE534905T1 (de) Cop1-moleküle und verwendungen davon
WO2012129408A3 (en) Biomarkers for aggressive prostate cancer
WO2009111033A3 (en) Detection of biomarkers and biomarker complexes
WO2008048508A3 (en) Prognostic biomarkers in patients with ovarian cancer
PT2208070E (pt) Testes de diagnóstico, preditivos e de prognóstico para o cancro
WO2008106648A3 (en) Immunoassays exhibiting a reduction in prozone phenomena
ATE507720T1 (de) Nachweis von lysophosphatidylcholin für die prognose oder diagnose eines systemischen entzündungszustands
DK2211180T3 (da) Anvendelse af protein SATB2 som markør til at skelne colorectal cancer fra andre former for cancer
EA201391627A1 (ru) Анализ на наличие лизилоксидазоподобных белков 2 и способы его применения
WO2013023144A3 (en) Diagnostic biomarker profiles for the detection and diagnosis of parkinsons disease
WO2007092173A3 (en) Raman spectroscopic lateral flow test strip assays
WO2007082073A3 (en) Biomarkers for oral tongue cancer metastasis and extracapsular spread (ecs)
WO2015077382A3 (en) Combined cytology and molecular testing for early detection of esophageal adenocarcinoma

Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]