BRPI0720361A2 - Método para medir aglutinação de uma ou mais partículas em um ensaio de aglutinação induzida por alvo efetuado em uma câmara de reação, e, kit e dispositivo para medir um ou mais parâmetros de aglutinação de partículas em um ensaio de aglutinação induzida por alvo - Google Patents

Método para medir aglutinação de uma ou mais partículas em um ensaio de aglutinação induzida por alvo efetuado em uma câmara de reação, e, kit e dispositivo para medir um ou mais parâmetros de aglutinação de partículas em um ensaio de aglutinação induzida por alvo

Info

Publication number
BRPI0720361A2
BRPI0720361A2 BRPI0720361-6A2A BRPI0720361A BRPI0720361A2 BR PI0720361 A2 BRPI0720361 A2 BR PI0720361A2 BR PI0720361 A BRPI0720361 A BR PI0720361A BR PI0720361 A2 BRPI0720361 A2 BR PI0720361A2
Authority
BR
Brazil
Prior art keywords
agglutination
particles
target
reaction chamber
test performed
Prior art date
Application number
BRPI0720361-6A2A
Other languages
English (en)
Inventor
Wendy U Dittmer
Kievit Peggy De
Jeroen H Nieuwenhuis
Menno W Prins
Ijzendoorn Leonardus J Van
Xander J A Janssen
Original Assignee
Koninkl Philips Electronics Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP06126507A external-priority patent/EP1936350A1/en
Application filed by Koninkl Philips Electronics Nv filed Critical Koninkl Philips Electronics Nv
Publication of BRPI0720361A2 publication Critical patent/BRPI0720361A2/pt
Publication of BRPI0720361A8 publication Critical patent/BRPI0720361A8/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/02—Investigating particle size or size distribution
    • G01N15/0266—Investigating particle size or size distribution with electrical classification
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y25/00—Nanomagnetism, e.g. magnetoimpedance, anisotropic magnetoresistance, giant magnetoresistance or tunneling magnetoresistance
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/72—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables
    • G01N27/74—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids
    • G01N27/745—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids for detecting magnetic beads used in biochemical assays
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/02—Measuring direction or magnitude of magnetic fields or magnetic flux
    • G01R33/06—Measuring direction or magnitude of magnetic fields or magnetic flux using galvano-magnetic devices
    • G01R33/09—Magnetoresistive devices
    • G01R33/093—Magnetoresistive devices using multilayer structures, e.g. giant magnetoresistance sensors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/12—Measuring magnetic properties of articles or specimens of solids or fluids
    • G01R33/1269—Measuring magnetic properties of articles or specimens of solids or fluids of molecules labeled with magnetic beads
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N2015/0092—Monitoring flocculation or agglomeration
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/806—Electrical property or magnetic property

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Cell Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biotechnology (AREA)
  • Dispersion Chemistry (AREA)
  • Electrochemistry (AREA)
  • Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
BRPI0720361A 2006-12-19 2007-12-18 Método para medir aglutinação de uma ou mais partículas em um ensaio de aglutinação induzida por alvo efetuado em uma câmara de reação, e, kit e dispositivo para medir um ou mais parâmetros de aglutinação de partículas em um ensaio de aglutinação induzida por alvo BRPI0720361A8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP06126507A EP1936350A1 (en) 2006-12-19 2006-12-19 A method for quantitatively measuring agglutination parameters
EP07116951 2007-09-21
PCT/IB2007/055195 WO2008075285A1 (en) 2006-12-19 2007-12-18 Measuring agglutination parameters

Publications (2)

Publication Number Publication Date
BRPI0720361A2 true BRPI0720361A2 (pt) 2013-12-24
BRPI0720361A8 BRPI0720361A8 (pt) 2015-10-13

Family

ID=39267975

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0720361A BRPI0720361A8 (pt) 2006-12-19 2007-12-18 Método para medir aglutinação de uma ou mais partículas em um ensaio de aglutinação induzida por alvo efetuado em uma câmara de reação, e, kit e dispositivo para medir um ou mais parâmetros de aglutinação de partículas em um ensaio de aglutinação induzida por alvo

Country Status (6)

Country Link
US (1) US8217647B2 (pt)
EP (1) EP2095091A1 (pt)
JP (1) JP5970153B2 (pt)
BR (1) BRPI0720361A8 (pt)
RU (1) RU2460058C2 (pt)
WO (1) WO2008075285A1 (pt)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8697029B2 (en) * 2002-04-18 2014-04-15 The Regents Of The University Of Michigan Modulated physical and chemical sensors
US9068977B2 (en) * 2007-03-09 2015-06-30 The Regents Of The University Of Michigan Non-linear rotation rates of remotely driven particles and uses thereof
US8283912B2 (en) 2007-04-03 2012-10-09 Koninklijke Philips Electronics N.V. Sensor device with magnetic washing means
WO2009037636A1 (en) * 2007-09-21 2009-03-26 Koninklijke Philips Electronics N.V. Sensor with high frequency ac magnetic field
BRPI0913469A2 (pt) * 2008-09-05 2015-12-22 Koninkl Philips Electronics Nv método para a realização de um ensaio de aglomerado, aparelho para a realização de um ensaio de aglomerado, uso de um método e uso de um aparelho
RU2011121883A (ru) * 2008-10-31 2012-12-10 Конинклейке Филипс Электроникс Н.В. Биосенсор с многокамерным контейнером
RU2011142784A (ru) * 2009-03-23 2013-04-27 Конинклейке Филипс Электроникс Н.В. Манипуляция магнитными частицами в биологическом образце
ATE539797T1 (de) * 2009-06-05 2012-01-15 Biotronik Crm Patent Ag Dispositif ameliore de detection de champ magnetique
WO2011021142A1 (en) * 2009-08-19 2011-02-24 Koninklijke Philips Electronics N.V. Detection of different target components by cluster formation
FR2963107B1 (fr) * 2010-07-21 2019-06-28 Diagast Complexe immuno-magnetique et son utilisation pour le groupage/phenotypage erythrocytaire
WO2012027747A2 (en) 2010-08-27 2012-03-01 The Regents Of The University Of Michigan Asynchronous magnetic bead rotation sensing systems and methods
US20140099663A1 (en) * 2010-11-15 2014-04-10 Regents Of The University Of Minnesota Gmr sensor
GB201100515D0 (en) * 2011-01-13 2011-02-23 Matrix Microscience Ltd Methods of capturing bindable targets from liquids
WO2012142179A2 (en) 2011-04-11 2012-10-18 The Regents Of The University Of Michigan Magnetically induced microspinning for super-detection and super-characterization of biomarkers and live cells
EP2541230A1 (en) * 2011-06-30 2013-01-02 Koninklijke Philips Electronics N.V. Detection of clusters of magnetic particles
EP2729256B1 (en) * 2011-07-07 2024-05-22 University College Dublin National University Of Ireland, Dublin Magnetic bead aggregation assay system and method for analysing and characterising magnetic bead aggregation and detection of target analytes
EP2780692A1 (en) 2011-11-14 2014-09-24 Koninklijke Philips N.V. Apparatus for cluster detection
US9797817B2 (en) 2012-05-03 2017-10-24 The Regents Of The University Of Michigan Multi-mode separation for target detection
DE102012105379B3 (de) * 2012-06-21 2013-07-25 Bernd Donner Sensor und Verfahren zur Messung von Partikeln in Medien
RU2653145C2 (ru) * 2012-09-04 2018-05-07 Конинклейке Филипс Н.В. Измерительное устройство и способ отбора образцов
AU2014301652B2 (en) * 2013-06-28 2018-04-19 Cic Nanogune Biosensor based on measurements of the clustering dynamics of magnetic particles
US9983110B2 (en) 2013-11-04 2018-05-29 The Regents Of The University Of Michigan Asynchronous magnetic bead rotation (AMBR) microviscometer for analysis of analytes
DE102015205202B4 (de) * 2015-03-23 2026-01-08 Bundesrepublik Deutschland, vertr. durch das Bundesministerium für Wirtschaft und Energie, dieses vertreten durch den Präsidenten der Physikalisch-Technischen Bundesanstalt Verfahren zum Messen einer magnetischen Eigenschaft von magnetischen Nanopartikeln
US11529628B2 (en) * 2017-04-28 2022-12-20 Ezdia Tech Inc. Automated immunoassay device and method using large magnetic particle complex
GB2566995B (en) 2017-09-29 2023-01-18 Cotton Mouton Diagnostics Ltd A method of detection
WO2021138570A1 (en) * 2019-12-31 2021-07-08 University Of Oregon Magnetoelastic microcarriers and monitoring system

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63188766A (ja) * 1987-02-02 1988-08-04 Nippon Telegr & Teleph Corp <Ntt> レ−ザ磁気免疫測定法および測定装置
JPH01112161A (ja) * 1987-07-20 1989-04-28 Hitachi Ltd 免疫凝集定量装置
JP2938918B2 (ja) * 1990-01-25 1999-08-25 ティーディーケイ株式会社 磁気微粒子の粒度測定方法
JPH05322894A (ja) * 1992-05-18 1993-12-07 Tdk Corp 生体物質量の測定方法及びそのための装置
DE19508772C2 (de) * 1995-03-01 1998-01-29 Schering Ag Verfahren und Verbindungen zur Detektion von Analyten mittels Remanenzmessung und deren Verwendung
US6437563B1 (en) 1997-11-21 2002-08-20 Quantum Design, Inc. Method and apparatus for making measurements of accumulations of magnetically susceptible particles combined with analytes
US6046585A (en) * 1997-11-21 2000-04-04 Quantum Design, Inc. Method and apparatus for making quantitative measurements of localized accumulations of target particles having magnetic particles bound thereto
WO2002035205A2 (en) 2000-10-20 2002-05-02 Binax, Inc. Process for detecting or quantifying a biological reaction using superparamagnetic label
US6518747B2 (en) 2001-02-16 2003-02-11 Quantum Design, Inc. Method and apparatus for quantitative determination of accumulations of magnetic particles
US6680177B2 (en) * 2001-12-07 2004-01-20 Cardiovascular Diagnostics, Inc. Low molecular weight heparin assay, system and reagent therefor
US20060194327A1 (en) 2003-07-30 2006-08-31 Koninklijke Philips Electronics N.V. On-chip magnetic particle sensor with improved snr
US20080309329A1 (en) 2003-07-30 2008-12-18 Koninklike Philips Electronics N.V. On-Chip Magnetic Sensor Device with Suppressed Cross-Talk
EP1751534A1 (en) * 2004-05-18 2007-02-14 Koninklijke Philips Electronics N.V. Magnetic rotation to improve signal-over-background in biosensing
EP1662256A1 (en) 2004-11-25 2006-05-31 Spinomix S.A. Tailored magnetic particles and method to produce same

Also Published As

Publication number Publication date
JP5970153B2 (ja) 2016-08-17
RU2009127754A (ru) 2011-01-27
WO2008075285A1 (en) 2008-06-26
BRPI0720361A8 (pt) 2015-10-13
JP2010513913A (ja) 2010-04-30
EP2095091A1 (en) 2009-09-02
US8217647B2 (en) 2012-07-10
RU2460058C2 (ru) 2012-08-27
US20100033158A1 (en) 2010-02-11

Similar Documents

Publication Publication Date Title
BRPI0720361A2 (pt) Método para medir aglutinação de uma ou mais partículas em um ensaio de aglutinação induzida por alvo efetuado em uma câmara de reação, e, kit e dispositivo para medir um ou mais parâmetros de aglutinação de partículas em um ensaio de aglutinação induzida por alvo
BRPI0911863A2 (pt) método para determinar a presença de um analito em uma amostra de estrutura queratinizada de um indivíduo.
EP2454587A4 (en) DEVICES, METHODS, AND KITS FOR DETERMINING ANALYZ CONCENTRATIONS
BRPI0918101A2 (pt) método para medir a troponina i em uma amostra, cartucho para ser utilizado em um dispositivo de ensaio e uso
BRPI0716163A2 (pt) mÉtodos e kits para detectar fluido cÉrebro-espinhal em uma amostra
GB0625595D0 (en) Sample analyser
EP2047268A4 (en) INDICATOR SYSTEM FOR DETERMINING ANALYTE CONCENTRATION
IL205271A0 (en) Immunoassay analysis method
BR112012027147A2 (pt) método in vitro destinado à liberação de um composto de vitamina d e à medição de um composto de vitamina d, composição e mistura de reagente, uso de uma composição de reagente e kits
BRPI0915736A2 (pt) dispositivo para analisar uma amostra química ou biológica
BRPI0720604B8 (pt) composição e método para detecção de desmineralização
BRPI0906907A2 (pt) Carreador para a detecção óptica em uma amostra em uma câmara de amostra adjacente e aparelho para a detecção óptica em uma amostra em uma câmara de amostra.
BR112013002041A2 (pt) composição de reagente multiuso e método para determinar simultaneamente as concentrações de pelo menos dois analitos em uma amostra de água
BRPI0820721A2 (pt) Reagentes e métodos para detectar analitos
ZA201001253B (en) Reagent kit for sample analysis and sample analysis method
BRPI0912982A2 (pt) métodos, dispositivos, kits e composições para detectar nematódeos
BRPI0917851A2 (pt) inibidor de adsorção da cistatina c, reagente e kit de medição da cistatina c, e, métodos para inibir a adsorção da cistatina c e para medir cistatina c em uma amostra
BRPI0912136A2 (pt) métodos para diagnosticar proliferação peroxissomal aumentada e para identificar uma substância para tratar proliferação peroxissomal aumentada, e, uso de pelo menos cinco analitos e de meios para a determinação de pelo menos cinco analitos
PT2294176T (pt) Adaptador de câmara de amostra, em particular para a criopreservação de amostras biológicas
BR112013007614A2 (pt) método para medir um analito em uma amostra, composição, mistura, uso e kit
BRPI0718200A2 (pt) aparelho para observar a aparência da superfície de uma amostra, e, método para observar a aparência da superfície de uma amostra
BRPI0619592A2 (pt) métodos para medir a qualidade da partícula de um composto de rapamicina, para determinar o tamanho de partícula médio de uma amostra e a cristalinidade de um composto de rapamicina, e para a purificação de rapamicina
BRPI0821597A2 (pt) Métodos para quantificar a quantidade de proteína derivada de plasma e proteína recombinante em uma amostra e para diferenciar proteína derivada de plasma e proteína recombinante em uma amostra, e, kit.
BRPI0914711A2 (pt) métodos para determinar a capacidade de gás e para avaliar a degradação de um material adsorvente, e, kit para realizar o método
GB2426592B (en) Method for the concentration measurement of gases

Legal Events

Date Code Title Description
B25D Requested change of name of applicant approved

Owner name: KONINKLIJKE PHILIPS N.V. (NL)

B25G Requested change of headquarter approved

Owner name: KONINKLIJKE PHILIPS N.V. (NL)

B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements