BRPI0606976A2 - processo para preparação de intermediários - Google Patents

processo para preparação de intermediários

Info

Publication number
BRPI0606976A2
BRPI0606976A2 BRPI0606976-2A BRPI0606976A BRPI0606976A2 BR PI0606976 A2 BRPI0606976 A2 BR PI0606976A2 BR PI0606976 A BRPI0606976 A BR PI0606976A BR PI0606976 A2 BRPI0606976 A2 BR PI0606976A2
Authority
BR
Brazil
Prior art keywords
intermediates
formula
preparation
azeotropic distillation
intermediate compounds
Prior art date
Application number
BRPI0606976-2A
Other languages
English (en)
Inventor
Linhua Wang
Kristine Anderson Dolbere
Frankie Lee Odom
Original Assignee
Syngenta Participations Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syngenta Participations Ag filed Critical Syngenta Participations Ag
Publication of BRPI0606976A2 publication Critical patent/BRPI0606976A2/pt
Publication of BRPI0606976B1 publication Critical patent/BRPI0606976B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C25/00—Compounds containing at least one halogen atom bound to a six-membered aromatic ring
    • C07C25/02—Monocyclic aromatic halogenated hydrocarbons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B39/00—Halogenation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

PROCESSO PARA A PREPARAçãO DE INTERMEDIáRIOS. A presente invenção refere-se a um processo para a produção de compostos intermediários de fórmula I no qual os substituintes são conforme definidos acima. O processo compreende reagir uma anilina substituida com HX aquoso, seguido pela remoção de água por destilação azeotrópica e diazotização e pirólise com um nitrito orgânico em temperaturas elevadas na auséncia de um catalisador de cobre. Alternativamente, HX gasoso pode ser usado para substituir HX aquoso no processo. Conseqúentemente, uma etapa de remoção de água por destilação azeotrópica pode ser eliminada, Os compostos intermediários de fórmula 1 são adequados como intermediários na preparação de derivados de 3-hidróxi-4-aril-5-oxopirazolina herbicidamente ativos.
BRPI0606976A 2005-02-09 2006-02-07 processo para a preparação de intermediários BRPI0606976B1 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65117505P 2005-02-09 2005-02-09
PCT/EP2006/001068 WO2006084663A1 (en) 2005-02-09 2006-02-07 Process for the preparation of intermediates

Publications (2)

Publication Number Publication Date
BRPI0606976A2 true BRPI0606976A2 (pt) 2009-07-28
BRPI0606976B1 BRPI0606976B1 (pt) 2015-12-08

Family

ID=36390191

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0606976A BRPI0606976B1 (pt) 2005-02-09 2006-02-07 processo para a preparação de intermediários

Country Status (21)

Country Link
US (1) US8030529B2 (pt)
EP (1) EP1848678B1 (pt)
JP (2) JP5254625B2 (pt)
KR (1) KR101355873B1 (pt)
CN (2) CN102603444A (pt)
AR (1) AR053123A1 (pt)
AU (1) AU2006212397B2 (pt)
BR (1) BRPI0606976B1 (pt)
CA (1) CA2596590C (pt)
DK (1) DK1848678T3 (pt)
EA (1) EA013842B1 (pt)
ES (1) ES2546960T3 (pt)
HU (1) HUE027652T2 (pt)
IL (1) IL184715A (pt)
MX (1) MX2007009341A (pt)
PL (1) PL1848678T3 (pt)
PT (1) PT1848678E (pt)
TW (1) TWI360533B (pt)
UA (1) UA89218C2 (pt)
WO (1) WO2006084663A1 (pt)
ZA (1) ZA200705880B (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101492343B (zh) * 2008-12-30 2011-08-10 中钢集团鞍山热能研究院有限公司 3,5-二甲基溴苯的制备方法
DK2406205T3 (en) 2009-03-12 2017-02-27 Bayer Ip Gmbh PROCEDURE FOR MANUFACTURING CHLOR AND BROMAROMATS
AR086590A1 (es) 2011-05-30 2014-01-08 Sumitomo Chemical Co Compuestos de ciclohexanona y herbicidas que los comprenden
CA2889315A1 (en) 2012-11-08 2014-05-15 Sumitomo Chemical Company, Limited Herbicide composition
US10759742B2 (en) 2016-07-22 2020-09-01 Syngenta Participations Ag Process for the preparation of phenylmalonic acid dinitriles
CN109336762B (zh) * 2018-11-30 2021-03-16 江苏富鼎化学有限公司 2-(2,6-二乙基-4-甲基苯)丙二酸二乙酯的合成方法
CN114907181B (zh) * 2021-02-09 2024-04-23 北京颖泰嘉和生物科技股份有限公司 用于桑德迈尔反应的装置和连续制备2,6-二乙基-4-甲基溴苯的方法
WO2023044364A1 (en) 2021-09-15 2023-03-23 Enko Chem, Inc. Protoporphyrinogen oxidase inhibitors
CN116573986A (zh) * 2023-05-12 2023-08-11 顺毅南通化工有限公司 一种2,6-二乙基-4-甲基溴苯的合成方法

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE600706C (de) * 1933-03-24 1934-07-30 I G Farbenindustrie Akt Ges Verfahren zur Herstellung aromatischer, im Kern fluorierter Verbindungen
DE1695659B1 (de) * 1967-12-18 1971-12-16 Ruetgerswerke Ag Verfahren zur Herstellung von 2-Chlorpyridinen
JPS59112965A (ja) 1982-12-20 1984-06-29 Koei Chem Co Ltd ４−クロルピリジン塩酸塩の製造法
FR2586247B1 (fr) * 1985-08-19 1987-11-20 Rhone Poulenc Spec Chim Procede de preparation de composes aromatiques fluores
US4822927A (en) * 1987-11-24 1989-04-18 Mallinckrodt, Inc. Continuous decomposition of diazonium fluorides
JPH01283230A (ja) * 1988-05-09 1989-11-14 Mitsui Toatsu Chem Inc 芳香族弗素化合物の製造方法
AU672578B2 (en) 1991-03-19 1996-10-10 Novartis Ag Novel herbicidally, acaricidally and insecticidally active compounds
DE4109208A1 (de) 1991-03-21 1992-09-24 Bayer Ag 3-hydroxy-4-aryl-5-oxo-pyrazolin-derivate
DE4111214A1 (de) 1991-04-06 1992-10-08 Bayer Ag Verfahren zur herstellung von 2-chlorpyridinen
ATE177093T1 (de) 1993-07-05 1999-03-15 Bayer Ag Substituierte aryl-ketoenolheterocyclen
MX9705247A (es) * 1995-01-13 1997-10-31 Novartis Ag Derivados de 4-aril- y 4-heteroaril-5-oxo-pirazolina que tienen propiedades plaguicidas.
JP4036470B2 (ja) 1995-02-13 2008-01-23 バイエル・アクチエンゲゼルシヤフト 除草剤および有害生物防除剤としての２−フェニル置換複素環式１，３−ケトエノール
DE19517186A1 (de) * 1995-05-11 1996-11-14 Bayer Ag Verfahren zur Herstellung substituierter 2-Fluor-pyrimidine
HUP9802279A3 (en) 1995-06-30 2001-05-28 Bayer Ag Dialkyl phenyl halide-substituted keto-enols for use as herbicides and pesticides
EP1062217B1 (en) 1998-03-13 2003-06-04 Syngenta Participations AG Herbicidally active 3-hydroxy-4-aryl-5-oxopyrazoline derivatives
BR0011700A (pt) * 1999-06-16 2002-03-05 Syngenta Participations Ag Dinitrilas de ácido arilmalÈnico substituìdo como intermediários para a preparação de herbicidas
KR100752941B1 (ko) 1999-06-16 2007-08-30 신젠타 파티서페이션즈 아게 제초제 유도체의 제조방법
DE60220658T2 (de) 2001-04-05 2008-02-21 Sumitomo Chemical Co., Ltd. Verfahren zur produktion von 2,6-dihalogenopurinen
AR042282A1 (es) 2002-12-05 2005-06-15 Syngenta Participations Ag Proceso para la preparacion de dinitrilos de acido fenilmalonico

Also Published As

Publication number Publication date
IL184715A (en) 2013-03-24
AU2006212397B2 (en) 2011-05-12
WO2006084663A1 (en) 2006-08-17
CA2596590A1 (en) 2006-08-17
HUE027652T2 (en) 2016-11-28
ES2546960T3 (es) 2015-09-30
EP1848678A1 (en) 2007-10-31
TW200640830A (en) 2006-12-01
CA2596590C (en) 2014-01-21
DK1848678T3 (en) 2015-09-21
AR053123A1 (es) 2007-04-25
CN102603444A (zh) 2012-07-25
KR101355873B1 (ko) 2014-02-03
PL1848678T3 (pl) 2015-11-30
ZA200705880B (en) 2008-08-27
TWI360533B (en) 2012-03-21
CN101115704A (zh) 2008-01-30
JP5254625B2 (ja) 2013-08-07
JP2012167122A (ja) 2012-09-06
IL184715A0 (en) 2007-12-03
JP5411319B2 (ja) 2014-02-12
MX2007009341A (es) 2007-09-21
PT1848678E (pt) 2015-10-12
US8030529B2 (en) 2011-10-04
EA200701616A1 (ru) 2008-02-28
EP1848678B1 (en) 2015-07-22
EA013842B1 (ru) 2010-08-30
BRPI0606976B1 (pt) 2015-12-08
US20090023964A1 (en) 2009-01-22
UA89218C2 (ru) 2010-01-11
JP2008529986A (ja) 2008-08-07
KR20070110290A (ko) 2007-11-16
AU2006212397A1 (en) 2006-08-17
CN101115704B (zh) 2012-03-28

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Legal Events

Date Code Title Description
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 07/02/2006, OBSERVADAS AS CONDICOES LEGAIS.

B25G Requested change of headquarter approved
B25A Requested transfer of rights approved