CR9221A - Procesos para preparar eteres aromaticos - Google Patents

Procesos para preparar eteres aromaticos

Info

Publication number
CR9221A
CR9221A CR9221A CR9221A CR9221A CR 9221 A CR9221 A CR 9221A CR 9221 A CR9221 A CR 9221A CR 9221 A CR9221 A CR 9221A CR 9221 A CR9221 A CR 9221A
Authority
CR
Costa Rica
Prior art keywords
eteres
processes
compound
formula
prepare aromatic
Prior art date
Application number
CR9221A
Other languages
English (en)
Inventor
Tawfik Gharbaoui
John R Fritch
Ashwin M Krishnan
Beverly Wolgast Throop
Naomi S Kato
Original Assignee
Arena Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arena Pharm Inc filed Critical Arena Pharm Inc
Publication of CR9221A publication Critical patent/CR9221A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

La invencion divulga: Un proceso para preparar un compuesto de formula (I); donde dicho proceso comprende hacer reaccionar un compuesto de formula (II): donde L es un grupo saliente, con un compuesto de formula (III) en presencia de una base y una sal, formando de ese modo el compuesto de formula (I). Los sustituyentes y variables se definen en las reivindicaciones.
CR9221A 2005-01-10 2007-07-02 Procesos para preparar eteres aromaticos CR9221A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US64262705P 2005-01-10 2005-01-10

Publications (1)

Publication Number Publication Date
CR9221A true CR9221A (es) 2007-10-23

Family

ID=36297260

Family Applications (1)

Application Number Title Priority Date Filing Date
CR9221A CR9221A (es) 2005-01-10 2007-07-02 Procesos para preparar eteres aromaticos

Country Status (29)

Country Link
US (1) US7812159B2 (es)
EP (1) EP1838697B1 (es)
JP (1) JP2008526881A (es)
KR (1) KR20070098906A (es)
CN (1) CN101115739A (es)
AR (1) AR056917A1 (es)
AT (1) ATE462701T1 (es)
AU (1) AU2006205176A1 (es)
BR (1) BRPI0606676A2 (es)
CA (1) CA2593344A1 (es)
CR (1) CR9221A (es)
DE (1) DE602006013271D1 (es)
DK (1) DK1838697T3 (es)
DO (1) DOP2006000010A (es)
EA (1) EA014156B1 (es)
ES (1) ES2341281T3 (es)
GE (1) GEP20105071B (es)
GT (1) GT200600007A (es)
HN (1) HN2006000970A (es)
IL (1) IL184366A0 (es)
MX (1) MX2007008377A (es)
NO (1) NO20074055L (es)
NZ (1) NZ556218A (es)
PE (2) PE20091401A1 (es)
SG (1) SG158864A1 (es)
TW (1) TW200637844A (es)
UA (1) UA92733C2 (es)
WO (1) WO2006076243A1 (es)
ZA (1) ZA200705473B (es)

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KR101078098B1 (ko) 2003-01-14 2011-10-28 아레나 파마슈티칼스, 인크. 대사 조절제로서의 １,２,３-삼치환된 아릴 및 헤테로아릴유도체, 및 당뇨병 및 고혈당증을 비롯한 이에 관련된장애의 예방 및 치료
AR045047A1 (es) * 2003-07-11 2005-10-12 Arena Pharm Inc Derivados arilo y heteroarilo trisustituidos como moduladores del metabolismo y de la profilaxis y tratamiento de desordenes relacionados con los mismos
MY148521A (en) * 2005-01-10 2013-04-30 Arena Pharm Inc Substituted pyridinyl and pyrimidinyl derivatives as modulators of metabolism and the treatment of disorders related thereto
KR20100120689A (ko) * 2008-02-22 2010-11-16 아이알엠 엘엘씨 Ｇｐｒ119 활성의 조절제로서의 화합물 및 조성물
CN108558740B (zh) 2010-01-27 2021-10-19 艾尼纳制药公司 S1p1受体调节剂及其盐的制备方法
WO2011113947A1 (en) 2010-03-18 2011-09-22 Boehringer Ingelheim International Gmbh Combination of a gpr119 agonist and the dpp-iv inhibitor linagliptin for use in the treatment of diabetes and related conditions
WO2012025811A1 (en) 2010-08-23 2012-03-01 Lupin Limited Indolylpyrimidines as modulators of gpr119
SG188548A1 (en) 2010-09-22 2013-04-30 Arena Pharm Inc Modulators of the gpr119 receptor and the treatment of disorders related thereto
CA2818050A1 (en) 2010-11-26 2012-05-31 Lupin Limited Bicyclic gpr119 modulators
WO2012170867A1 (en) 2011-06-09 2012-12-13 Rhizen Pharmaceuticals Sa Novel compounds as modulators of gpr-119
PL3242666T3 (pl) 2015-01-06 2025-02-17 Arena Pharmaceuticals, Inc. Związek do zastosowania w leczeniu dolegliwości związanych z receptorem s1p1
HUE060476T2 (hu) 2015-06-22 2023-03-28 Arena Pharm Inc (R)-2-(7-(4-ciklopentil-3-(trifluormetil)benziloxi)-1,2,3,4- tetrahidrociklopenta[B]indol-3-il)ecetsav kristályos L-arginin-sója S1P1 receptorral kapcsolatos rendellenességek esetén való alkalmazásra
WO2018055527A1 (en) 2016-09-20 2018-03-29 Glaxosmithkline Intellectual Property (No.2) Limited Trpv4 antagonists
TW201825458A (zh) 2016-09-20 2018-07-16 英商葛蘭素史克智慧財產（第二）有限公司 Ｔｒｐｖ４拮抗劑
JP7106528B2 (ja) 2016-09-20 2022-07-26 グラクソスミスクライン、インテレクチュアル、プロパティー、（ナンバー２）、リミテッド Ｔｒｐｖ４拮抗薬
WO2018151873A1 (en) 2017-02-16 2018-08-23 Arena Pharmaceuticals, Inc. Compounds and methods for treatment of primary biliary cholangitis
US12156866B2 (en) 2018-06-06 2024-12-03 Arena Pharmaceuticals, Inc. Methods of treating conditions related to the S1P1 receptor

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Also Published As

Publication number Publication date
WO2006076243A1 (en) 2006-07-20
DE602006013271D1 (de) 2010-05-12
ATE462701T1 (de) 2010-04-15
DOP2006000010A (es) 2006-07-31
NZ556218A (en) 2010-10-29
UA92733C2 (ru) 2010-12-10
ES2341281T3 (es) 2010-06-17
US7812159B2 (en) 2010-10-12
MX2007008377A (es) 2007-09-07
SG158864A1 (en) 2010-02-26
JP2008526881A (ja) 2008-07-24
EA014156B1 (ru) 2010-10-29
ZA200705473B (en) 2009-07-29
HK1102810A1 (en) 2007-12-07
EA200701470A1 (ru) 2008-02-28
EP1838697B1 (en) 2010-03-31
AU2006205176A1 (en) 2006-07-20
AR056917A1 (es) 2007-11-07
US20060155129A1 (en) 2006-07-13
EP1838697A1 (en) 2007-10-03
TW200637844A (en) 2006-11-01
DK1838697T3 (da) 2010-06-28
GEP20105071B (en) 2010-09-10
PE20060836A1 (es) 2006-09-02
BRPI0606676A2 (pt) 2009-07-07
HN2006000970A (es) 2010-04-19
CA2593344A1 (en) 2006-07-20
KR20070098906A (ko) 2007-10-05
GT200600007A (es) 2006-08-01
IL184366A0 (en) 2007-10-31
PE20091401A1 (es) 2009-09-18
CN101115739A (zh) 2008-01-30
NO20074055L (no) 2007-09-25

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