CR9221A - Procesos para preparar eteres aromaticos - Google Patents

Procesos para preparar eteres aromaticos

Info

Publication number
CR9221A
CR9221A CR9221A CR9221A CR9221A CR 9221 A CR9221 A CR 9221A CR 9221 A CR9221 A CR 9221A CR 9221 A CR9221 A CR 9221A CR 9221 A CR9221 A CR 9221A
Authority
CR
Costa Rica
Prior art keywords
eteres
processes
compound
formula
prepare aromatic
Prior art date
Application number
CR9221A
Other languages
English (en)
Inventor
Tawfik Gharbaoui
John R Fritch
Ashwin M Krishnan
Beverly Wolgast Throop
Naomi S Kato
Original Assignee
Arena Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arena Pharm Inc filed Critical Arena Pharm Inc
Publication of CR9221A publication Critical patent/CR9221A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

La invencion divulga: Un proceso para preparar un compuesto de formula (I); donde dicho proceso comprende hacer reaccionar un compuesto de formula (II): donde L es un grupo saliente, con un compuesto de formula (III) en presencia de una base y una sal, formando de ese modo el compuesto de formula (I). Los sustituyentes y variables se definen en las reivindicaciones.
CR9221A 2005-01-10 2007-07-02 Procesos para preparar eteres aromaticos CR9221A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US64262705P 2005-01-10 2005-01-10

Publications (1)

Publication Number Publication Date
CR9221A true CR9221A (es) 2007-10-23

Family

ID=36297260

Family Applications (1)

Application Number Title Priority Date Filing Date
CR9221A CR9221A (es) 2005-01-10 2007-07-02 Procesos para preparar eteres aromaticos

Country Status (29)

Country Link
US (1) US7812159B2 (es)
EP (1) EP1838697B1 (es)
JP (1) JP2008526881A (es)
KR (1) KR20070098906A (es)
CN (1) CN101115739A (es)
AR (1) AR056917A1 (es)
AT (1) ATE462701T1 (es)
AU (1) AU2006205176A1 (es)
BR (1) BRPI0606676A2 (es)
CA (1) CA2593344A1 (es)
CR (1) CR9221A (es)
DE (1) DE602006013271D1 (es)
DK (1) DK1838697T3 (es)
DO (1) DOP2006000010A (es)
EA (1) EA014156B1 (es)
ES (1) ES2341281T3 (es)
GE (1) GEP20105071B (es)
GT (1) GT200600007A (es)
HN (1) HN2006000970A (es)
IL (1) IL184366A0 (es)
MX (1) MX2007008377A (es)
NO (1) NO20074055L (es)
NZ (1) NZ556218A (es)
PE (2) PE20060836A1 (es)
SG (1) SG158864A1 (es)
TW (1) TW200637844A (es)
UA (1) UA92733C2 (es)
WO (1) WO2006076243A1 (es)
ZA (1) ZA200705473B (es)

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MXPA05007485A (es) 2003-01-14 2006-01-30 Arena Pharm Inc Derivados de arilo y heteroarilo 1,2,3-trisubstituidos como moduladores del metabolismo y la profilaxis y tratamiento de trastornos relacionados con ello tales como diabetes e hiperglicemia.
AR045047A1 (es) * 2003-07-11 2005-10-12 Arena Pharm Inc Derivados arilo y heteroarilo trisustituidos como moduladores del metabolismo y de la profilaxis y tratamiento de desordenes relacionados con los mismos
MY148521A (en) * 2005-01-10 2013-04-30 Arena Pharm Inc Substituted pyridinyl and pyrimidinyl derivatives as modulators of metabolism and the treatment of disorders related thereto
EP2262496A1 (en) * 2008-02-22 2010-12-22 Irm Llc Compounds and compositions as modulators of gpr119 activity
JP5856980B2 (ja) 2010-01-27 2016-02-10 アリーナ ファーマシューティカルズ, インコーポレイテッド (R)−2−(7−(4−シクロペンチル−3−(トリフルオロメチル)ベンジルオキシ)−1,2,3,4−テトラヒドロシクロペンタ[b]インドール−3−イル)酢酸およびその塩の調製のためのプロセス
EP2547339A1 (en) 2010-03-18 2013-01-23 Boehringer Ingelheim International GmbH Combination of a gpr119 agonist and the dpp-iv inhibitor linagliptin for use in the treatment of diabetes and related conditions
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EP3323818A1 (en) 2010-09-22 2018-05-23 Arena Pharmaceuticals, Inc. Modulators of the gpr119 receptor and the treatment of disorders related thereto
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CA2836487A1 (en) 2011-06-09 2012-12-13 Rhizen Pharmaceuticals Sa Novel compounds as modulators of gpr-119
PL3242666T3 (pl) 2015-01-06 2025-02-17 Arena Pharmaceuticals, Inc. Związek do zastosowania w leczeniu dolegliwości związanych z receptorem s1p1
BR112017027656B1 (pt) 2015-06-22 2023-12-05 Arena Pharmaceuticals, Inc. Hábito cristalino de placa livre de sal de l-arginina de ácido (r)-2-(7-(4- ciclopentil-3-(trifluorometil)benzilóxi)- 1,2,3,4-tetra-hidrociclo-penta[b]indol-3- il)acético, composição farmacêutica que o compreende, seus usos e método de preparação do mesmo
RU2019110821A (ru) 2016-09-20 2020-10-22 Глэксосмитклайн Интеллекчуал Проперти (Но.2) Лимитед Антагонисты trpv4
JP2019532054A (ja) 2016-09-20 2019-11-07 グラクソスミスクライン、インテレクチュアル、プロパティー、(ナンバー2)、リミテッドGlaxosmithkline Intellectual Property (No.2) Limited Trpv4拮抗薬
TW201825458A (zh) 2016-09-20 2018-07-16 英商葛蘭素史克智慧財產(第二)有限公司 Trpv4拮抗劑
MX2019009841A (es) 2017-02-16 2020-01-30 Arena Pharm Inc Compuestos y metodos para el tratamiento de la colangitis biliar primaria.
CA3102136A1 (en) 2018-06-06 2019-12-12 Arena Pharmaceuticals, Inc. Methods of treating conditions related to the s1p1 receptor

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Also Published As

Publication number Publication date
JP2008526881A (ja) 2008-07-24
KR20070098906A (ko) 2007-10-05
TW200637844A (en) 2006-11-01
GT200600007A (es) 2006-08-01
EA014156B1 (ru) 2010-10-29
WO2006076243A1 (en) 2006-07-20
US20060155129A1 (en) 2006-07-13
AR056917A1 (es) 2007-11-07
DE602006013271D1 (de) 2010-05-12
EP1838697B1 (en) 2010-03-31
MX2007008377A (es) 2007-09-07
HK1102810A1 (en) 2007-12-07
ATE462701T1 (de) 2010-04-15
CN101115739A (zh) 2008-01-30
CA2593344A1 (en) 2006-07-20
NZ556218A (en) 2010-10-29
EP1838697A1 (en) 2007-10-03
NO20074055L (no) 2007-09-25
PE20060836A1 (es) 2006-09-02
DOP2006000010A (es) 2006-07-31
PE20091401A1 (es) 2009-09-18
UA92733C2 (ru) 2010-12-10
ES2341281T3 (es) 2010-06-17
ZA200705473B (en) 2009-07-29
DK1838697T3 (da) 2010-06-28
IL184366A0 (en) 2007-10-31
SG158864A1 (en) 2010-02-26
US7812159B2 (en) 2010-10-12
GEP20105071B (en) 2010-09-10
HN2006000970A (es) 2010-04-19
EA200701470A1 (ru) 2008-02-28
BRPI0606676A2 (pt) 2009-07-07
AU2006205176A1 (en) 2006-07-20

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