BRPI0607323A2 - composições e uso de polipeptìdeos e kits para a detecção de anticorpo que se liga especificamente a um polipeptìdeo - Google Patents
composições e uso de polipeptìdeos e kits para a detecção de anticorpo que se liga especificamente a um polipeptìdeoInfo
- Publication number
- BRPI0607323A2 BRPI0607323A2 BRPI0607323-9A BRPI0607323A BRPI0607323A2 BR PI0607323 A2 BRPI0607323 A2 BR PI0607323A2 BR PI0607323 A BRPI0607323 A BR PI0607323A BR PI0607323 A2 BRPI0607323 A2 BR PI0607323A2
- Authority
- BR
- Brazil
- Prior art keywords
- polypeptides
- compositions
- polypeptide
- specifically binds
- kits
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/085—Staphylococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
- C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Gram-positive bacteria
- C07K16/1271—Micrococcaceae (F); Staphylococcaceae (F), e.g. Staphylococcus (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Gram-positive bacteria
- C07K16/1275—Streptococcus (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Gram-positive bacteria
- C07K16/1285—Gram-positive bacteria from Corynebacterium (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Gram-positive bacteria
- C07K16/1289—Mycobacteriaceae (F)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
- G01N33/56938—Staphylococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
- C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/82—Proteins from microorganisms
- Y10S530/825—Bacteria
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Mycology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
Abstract
COMPOSIçõES E USO DE POLIPEPTìDEOS E KITS PARA A DETECçãO DE ANTICORPO QUE SE LIGA ESPECIFICAMENTE A UM POLIPEPTìDEO. A presente invenção fornece polipeptideos isolados que podem ser isolados partindo de um Staphylococcus spp. São também fornecidas pela presente invenção composições que incluem um ou mais dos polipeptideos e métodos para a produção e métodos para a utilização dos polipeptideos.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65284305P | 2005-02-14 | 2005-02-14 | |
| US60/652,843 | 2005-02-14 | ||
| PCT/US2006/005058 WO2006088803A2 (en) | 2005-02-14 | 2006-02-14 | Polypeptides from staphylococcus aureus and methods of use |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BRPI0607323A2 true BRPI0607323A2 (pt) | 2009-09-01 |
| BRPI0607323B1 BRPI0607323B1 (pt) | 2020-12-22 |
| BRPI0607323B8 BRPI0607323B8 (pt) | 2021-05-25 |
Family
ID=36694403
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0607323A BRPI0607323B8 (pt) | 2005-02-14 | 2006-02-14 | composições, usos de polipeptídeos e de anticorpos, bem como kits para a detecção de anticorpo que se liga especificamente a um polipeptídeo |
Country Status (12)
| Country | Link |
|---|---|
| US (13) | US8007811B2 (pt) |
| EP (1) | EP1853306B1 (pt) |
| JP (3) | JP2008532935A (pt) |
| CN (2) | CN101119744B (pt) |
| AU (1) | AU2006214534B2 (pt) |
| BR (1) | BRPI0607323B8 (pt) |
| CA (1) | CA2597263C (pt) |
| DK (1) | DK1853306T3 (pt) |
| ES (1) | ES2586125T3 (pt) |
| MX (1) | MX2007009828A (pt) |
| NZ (4) | NZ560612A (pt) |
| WO (1) | WO2006088803A2 (pt) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5830479A (en) * | 1994-02-09 | 1998-11-03 | Willmar Poultry Company, Inc. | Active immunization using a siderophore receptor protein |
| WO1995021627A1 (en) * | 1994-02-09 | 1995-08-17 | Willmar Poultry Company, Inc. | Active immunization using a siderophore receptor protein |
| DE19962924A1 (de) | 1999-12-24 | 2001-07-05 | Bayer Ag | Substituierte Oxazolidinone und ihre Verwendung |
| CA2433561C (en) * | 2001-01-03 | 2014-04-01 | Willmar Poultry Company, Inc. | Compositions including gram negative siderophore receptor proteins and methods of use |
| EP1678316B1 (en) | 2003-09-19 | 2011-08-17 | Epitopix, LLC | Campylobacter polypeptides and methods of use |
| NZ560612A (en) * | 2005-02-14 | 2011-01-28 | Epitopix Llc | Polypeptides from staphylococcus aureus and methods of use |
| AU2007221321B2 (en) * | 2006-02-22 | 2012-06-28 | The Texas A & M University System | Antibodies recognizing a highly expressed putative antigen of CA-MRSA and methods of use |
| JP5564249B2 (ja) * | 2006-06-23 | 2014-07-30 | アレシア・バイオセラピューティクス・インコーポレーテッド | 癌に関与するポリヌクレオチド配列およびポリペプチド配列 |
| WO2010060186A1 (en) | 2008-11-03 | 2010-06-03 | Alethia Biotherapeutics Inc. | Antibodies that specifically block the biological activity of a tumor antigen |
| EP2411046B1 (en) * | 2009-03-23 | 2017-12-06 | Epitopix, LLC | Polypeptides and immunizing compositions containing gram positive polypeptides and methods of use |
| JP6294221B2 (ja) | 2011-03-31 | 2018-03-14 | アー・デー・ツェー・セラピューティクス・エス・アー | 腎臓関連抗原1に対する抗体およびその抗原結合性フラグメント |
| TR201908872T4 (tr) | 2012-01-09 | 2019-07-22 | Adc Therapeutics Sa | Üçlü negatif meme kanserini tedavi etmek için ajanlar. |
| US9169477B2 (en) | 2012-01-27 | 2015-10-27 | Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center | Compositions and methods for immunization against bacteria expressing a carbapenemase |
| US10100093B2 (en) | 2013-12-31 | 2018-10-16 | Epitopix Llc | Polypeptides and immunizing compositions containing Burkholderia polypeptides and methods of use |
| US11000582B2 (en) | 2015-07-10 | 2021-05-11 | Epitopix, Llc | Proteins and immunizing compositions containing klebsiella proteins and methods of use |
| WO2017024038A1 (en) * | 2015-08-03 | 2017-02-09 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Solar concentrator for a tower-mounted central receiver |
| US10166280B2 (en) | 2016-06-08 | 2019-01-01 | Epitopix, Llc | Polypeptides and immunizing compositions containing Bacillus polypeptides and methods of use |
| US10738338B2 (en) | 2016-10-18 | 2020-08-11 | The Research Foundation for the State University | Method and composition for biocatalytic protein-oligonucleotide conjugation and protein-oligonucleotide conjugate |
| TWI733412B (zh) * | 2020-04-13 | 2021-07-11 | 華邦電子股份有限公司 | 具有氣隙之半導體元件及其製造方法 |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4981685A (en) | 1986-03-07 | 1991-01-01 | Utah State University Foundation | Bacterial extract vaccines for veterinary application |
| US5554372A (en) | 1986-09-22 | 1996-09-10 | Emory University | Methods and vaccines comprising surface-active copolymers |
| US5292869A (en) | 1989-04-27 | 1994-03-08 | The Board Of Governors Of The University | Method for isolating and purifying transferrin and lactoferrin receptor proteins from bacteria and the preparation of vaccines containing the same |
| WO1995021627A1 (en) | 1994-02-09 | 1995-08-17 | Willmar Poultry Company, Inc. | Active immunization using a siderophore receptor protein |
| US5830479A (en) | 1994-02-09 | 1998-11-03 | Willmar Poultry Company, Inc. | Active immunization using a siderophore receptor protein |
| US5538733A (en) | 1994-07-07 | 1996-07-23 | Willmar Poultry Company, Inc. | Method of priming an immune response in a one-day old animal |
| US6403337B1 (en) * | 1996-01-05 | 2002-06-11 | Human Genome Sciences, Inc. | Staphylococcus aureus genes and polypeptides |
| EP0950068B1 (en) * | 1996-05-16 | 2005-11-09 | THE TEXAS A&M UNIVERSITY SYSTEM | Collagen binding protein compositions and methods of use |
| US6680195B1 (en) | 1997-11-26 | 2004-01-20 | Inhibitex, Inc. | Extracellular matrix-binding proteins from staphylococcus aureus |
| US6692739B1 (en) | 1998-08-31 | 2004-02-17 | Inhibitex, Inc. | Staphylococcal immunotherapeutics via donor selection and donor stimulation |
| US6703025B1 (en) | 1998-08-31 | 2004-03-09 | Inhibitex, Inc. | Multicomponent vaccines |
| US6682754B2 (en) | 1999-11-24 | 2004-01-27 | Willmar Poultry Company, Inc. | Ovo delivery of an immunogen containing implant |
| WO2001070955A2 (en) | 2000-03-21 | 2001-09-27 | Elitra Pharmaceuticals, Inc. | Identification of essential genes in prokaryotes |
| AT410173B (de) | 2000-06-08 | 2003-02-25 | Cistem Biotechnologies Gmbh | Antigene zusammensetzung |
| CA2433561C (en) * | 2001-01-03 | 2014-04-01 | Willmar Poultry Company, Inc. | Compositions including gram negative siderophore receptor proteins and methods of use |
| AT410798B (de) | 2001-01-26 | 2003-07-25 | Cistem Biotechnologies Gmbh | Verfahren zur identifizierung, isolierung und herstellung von antigenen gegen ein spezifisches pathogen |
| GB0107661D0 (en) | 2001-03-27 | 2001-05-16 | Chiron Spa | Staphylococcus aureus |
| CA2450939C (en) | 2001-06-15 | 2012-11-06 | The Provost Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin | Cross-reactive monoclonal and polyclonal antibodies which recognize surface proteins from coagulase-negative staphylococci and staphylococcus aureus |
| WO2003020875A2 (en) * | 2001-06-17 | 2003-03-13 | D-Squared Biotechnologies, Inc. | Staphylococci surface-exposed immunogenic polypeptides |
| US6720160B2 (en) | 2001-10-11 | 2004-04-13 | Helica Biosystems, Inc. | Method for simultaneous detection of multiple microbial antigens in biological specimens from mastitic animals |
| AU2003254555A1 (en) | 2002-07-26 | 2004-02-23 | Intercell Ag | S. aureus antigene |
| US6947260B2 (en) * | 2002-11-18 | 2005-09-20 | Hitachi Global Storage Technologies Netherlands B.V. | System and method of damping vibration on coil supports in high performance disk drives with rotary actuators |
| EP1678316B1 (en) | 2003-09-19 | 2011-08-17 | Epitopix, LLC | Campylobacter polypeptides and methods of use |
| US20070128183A1 (en) | 2004-04-27 | 2007-06-07 | Intercell Ag | Td antigens |
| EP1784220B1 (en) | 2004-08-26 | 2017-12-20 | The University Of Western Ontario | Bacterial iron acquisition targets |
| CA2581746A1 (en) | 2004-10-25 | 2006-06-08 | The University Of Western Ontario | Staphylococcus aureus isd protein-based anti-infectives |
| NZ560612A (en) | 2005-02-14 | 2011-01-28 | Epitopix Llc | Polypeptides from staphylococcus aureus and methods of use |
| EP2411046B1 (en) | 2009-03-23 | 2017-12-06 | Epitopix, LLC | Polypeptides and immunizing compositions containing gram positive polypeptides and methods of use |
-
2006
- 2006-02-14 NZ NZ560612A patent/NZ560612A/en not_active IP Right Cessation
- 2006-02-14 US US11/353,459 patent/US8007811B2/en not_active Expired - Lifetime
- 2006-02-14 NZ NZ597997A patent/NZ597997A/xx not_active IP Right Cessation
- 2006-02-14 NZ NZ589238A patent/NZ589238A/en not_active IP Right Cessation
- 2006-02-14 NZ NZ613923A patent/NZ613923A/en not_active IP Right Cessation
- 2006-02-14 AU AU2006214534A patent/AU2006214534B2/en not_active Ceased
- 2006-02-14 MX MX2007009828A patent/MX2007009828A/es active IP Right Grant
- 2006-02-14 WO PCT/US2006/005058 patent/WO2006088803A2/en not_active Ceased
- 2006-02-14 CN CN2006800049030A patent/CN101119744B/zh not_active Expired - Fee Related
- 2006-02-14 CN CN201310020750.0A patent/CN103143006B/zh not_active Expired - Fee Related
- 2006-02-14 CA CA2597263A patent/CA2597263C/en not_active Expired - Lifetime
- 2006-02-14 EP EP06734951.4A patent/EP1853306B1/en not_active Expired - Lifetime
- 2006-02-14 JP JP2007555321A patent/JP2008532935A/ja not_active Withdrawn
- 2006-02-14 BR BRPI0607323A patent/BRPI0607323B8/pt not_active IP Right Cessation
- 2006-02-14 DK DK06734951.4T patent/DK1853306T3/en active
- 2006-02-14 ES ES06734951.4T patent/ES2586125T3/es not_active Expired - Lifetime
- 2006-09-11 US US11/518,727 patent/US8025885B2/en active Active
- 2006-09-11 US US11/518,689 patent/US8007803B2/en active Active
-
2008
- 2008-03-18 US US12/077,268 patent/US8709436B2/en active Active
- 2008-11-17 US US12/272,021 patent/US8709760B2/en active Active
-
2012
- 2012-01-31 US US13/362,992 patent/US8961979B2/en not_active Expired - Lifetime
- 2012-12-05 JP JP2012266189A patent/JP2013053155A/ja not_active Withdrawn
-
2013
- 2013-07-01 US US13/932,875 patent/US20130287813A1/en not_active Abandoned
- 2013-07-01 US US13/932,870 patent/US20130288952A1/en not_active Abandoned
- 2013-07-01 US US13/932,863 patent/US20130280300A1/en not_active Abandoned
- 2013-07-01 US US13/932,877 patent/US20140005360A1/en not_active Abandoned
-
2015
- 2015-01-29 US US14/608,493 patent/US9266944B2/en not_active Expired - Lifetime
- 2015-05-01 JP JP2015094191A patent/JP6100826B2/ja not_active Expired - Fee Related
-
2016
- 2016-02-15 US US15/043,740 patent/US9623076B2/en not_active Expired - Lifetime
-
2017
- 2017-03-09 US US15/454,197 patent/US9981028B2/en not_active Expired - Lifetime
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BRPI0607323A2 (pt) | composições e uso de polipeptìdeos e kits para a detecção de anticorpo que se liga especificamente a um polipeptìdeo | |
| CY1124802T1 (el) | Δεσμευτικοι παραγοντες σκληροστινης | |
| CY1121291T1 (el) | Ανοσοδοκιμασιες ενισχυσης σηματος | |
| EA200970210A1 (ru) | Prlr-специфическое антитело и его применения | |
| CY1120951T1 (el) | Ανθρωπινα αντισωματα enanti-tau | |
| BR112013023540A2 (pt) | anticorpo, kit e método para a determinação de peptídeos amilóides | |
| MX2007010349A (es) | Composiciones y metodos para clasificar muestras biologicas. | |
| ECSP088543A (es) | Anticuerpos anti-ox40l y métodos que los utilizan | |
| ECSP099027A (es) | Anticuerpos anti-dll4 y métodos que los usan | |
| BRPI0812878B8 (pt) | anticorpo isolado ou parte funcional do mesmo, vetor, método para produzir um anticorpo ou uma parte funcional do mesmo, para produzir uma célula produtora de anticorpo e para produzir um anticorpo capaz de se ligar especificamente a rsv, composição, e, uso de um anticorpo ou parte funcional do mesmo ou de uma composição ou de vetor | |
| CO6351750A2 (es) | Composiciones y métodos para anticuerpos que se dirigen a la proteina de complementos c5 | |
| BRPI0909044B8 (pt) | anticorpo que se liga especificamente ao csf-1r humano,composição farmacêutica e uso dos mesmos | |
| AR057237A1 (es) | Metodos y composiciones para actuar sobre la poliubiquitina | |
| DE602006015793D1 (de) | Proteolipidmembran und lipidmembranen-biosensor | |
| WO2009007846A3 (en) | Methods for modifying, isolating, detecting, visualizing, and quantifying citrullinated and/or homocitrullinated peptides, polypeptides and proteins | |
| BRPI0606506A2 (pt) | polipeptìdeos de yersinia spp. e métodos de uso | |
| DK2021794T3 (da) | Anvendelse af protein S100A 12 som en markør for colorektal cancer | |
| BR112012019475A2 (pt) | "uso de um anticorpo monoclonal anti-cd 44 anticorpo anti-cd44 humanizado e kit para a detecção da presença de hnscc em uma amostra | |
| AR059096A1 (es) | Anticuerpos anti- efrina -b2 y metodos que usan estos | |
| DK1987357T3 (da) | Polypeptider, som genkendes af anti-Trichinella-antistoffer, og anvendelser deraf | |
| ATE476655T1 (de) | Doxorubicin-immuntest | |
| EA200702361A1 (ru) | АНТИТЕЛА ПРОТИВ csPCNA ИЗОФОРМЫ И ИХ ПРИМЕНЕНИЕ | |
| DE602006007967D1 (de) | Gegen das gemeinsame epitop von mutierten p53 gerichtete humane synthetische einzelkettenantikörper und anwendungen davon | |
| BRPI0514672A (pt) | polipeptìdeos de fusobacterium e métodos de uso | |
| ATE489623T1 (de) | Peptide zum nachweis von ehrlichia ewingii antikörper |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] | ||
| B12B | Appeal against refusal [chapter 12.2 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 22/12/2020, OBSERVADAS AS CONDICOES LEGAIS. |
|
| B16C | Correction of notification of the grant [chapter 16.3 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 14/02/2006 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF |
|
| B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE A 20A ANUIDADE. |