BRPI0610087A2 - composto para resfriamento - Google Patents

composto para resfriamento

Info

Publication number
BRPI0610087A2
BRPI0610087A2 BRPI0610087-2A BRPI0610087A BRPI0610087A2 BR PI0610087 A2 BRPI0610087 A2 BR PI0610087A2 BR PI0610087 A BRPI0610087 A BR PI0610087A BR PI0610087 A2 BRPI0610087 A2 BR PI0610087A2
Authority
BR
Brazil
Prior art keywords
nhch
och
formula
cooling
compounds
Prior art date
Application number
BRPI0610087-2A
Other languages
English (en)
Inventor
Karen Ann Bell
Stefan Michael Furrer
Christophe Lopin
Pablo Victor Krawec
Jay Patrick Slack
Original Assignee
Givaudan Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Givaudan Sa filed Critical Givaudan Sa
Publication of BRPI0610087A2 publication Critical patent/BRPI0610087A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G4/00—Chewing gum
    • A23G4/06—Chewing gum characterised by the composition containing organic or inorganic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/20—Synthetic spices, flavouring agents or condiments
    • A23L27/204—Aromatic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42—Amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q9/00—Preparations for removing hair or for aiding hair removal
    • A61Q9/02—Shaving preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/24—Thermal properties
    • A61K2800/244—Endothermic; Cooling; Cooling sensation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nutrition Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Cosmetics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Seasonings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Confectionery (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

COMPOSTOS PARA RESFRIAMENTO. A presente invenção refere-se a método para conferir um efeito de resfriamento para a pele ou para as membranas mucosas através da a- plicação as mesmas de pelo menos de um composto da fórmula I (a) na qual B é selecionado a partir de H, CH~ 3~, C~ 2~H~ 5~, OCH~ 3~, OC~ 2~H~ 5~; e OH; e (b) na qual A é uma porção da fórmula -CO-D, na qual D é selecionado a partir das seguinte porçóes:(i) -NR¹R², na qual R¹ e R² são independentemente selecionados a partir de H e grupos alifáticos de cadeia linear ou ramificada de C~ 1~-C~ 8~ alcoxialquila, hidroxialquila, grupos aralifáticos e de cicloalquila, ou R¹ e R² em conjunto com o átomo de nitrogénio ao qual eles estão ligados formam parte de anel heterocíclico de cinco ou seis elementos opcionalmente substituidos; (ii) -NHCH~ 2~COOCH~ 2~CH~ 3~, -NHCH~ 2~CONH~ 2~, -NHCH~ 2~CH~ 2~OCH~ 3~, -NHCH~ 2~CH2OH, -NHCH~ 2~ CH(OH)CH~ 2~OH e (iii) uma porção selecionada a partir do grupo que consiste em: Os compostos são úteis para prover efeitos de resfriamento em uma variedade de produtos tais como produtos alimentícios, confeitos, produtos de tabaco, bebidas, cosméticos, dentifrícios, preparações medicinais, líquidos para lavagem bucal ou produ- tos de toucador.
BRPI0610087-2A 2005-05-27 2006-05-24 composto para resfriamento BRPI0610087A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US68554805P 2005-05-27 2005-05-27
PCT/CH2006/000270 WO2006125334A1 (en) 2005-05-27 2006-05-24 Cooling compounds

Publications (1)

Publication Number Publication Date
BRPI0610087A2 true BRPI0610087A2 (pt) 2008-12-02

Family

ID=36751575

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0610087-2A BRPI0610087A2 (pt) 2005-05-27 2006-05-24 composto para resfriamento

Country Status (8)

Country Link
US (1) US20090105237A1 (pt)
EP (1) EP1885327A1 (pt)
JP (1) JP2009501132A (pt)
KR (1) KR20080020609A (pt)
CN (1) CN101184470A (pt)
BR (1) BRPI0610087A2 (pt)
MX (1) MX2007014456A (pt)
WO (1) WO2006125334A1 (pt)

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CN100582089C (zh) 2003-11-21 2010-01-20 吉万奥丹股份有限公司 N-取代的对-薄荷烷甲酰胺
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PL2510925T3 (pl) 2006-02-15 2017-03-31 Dendreon Pharmaceuticals, Inc. Drobnocząsteczkowe modulatory aktywności trp-p8
CN101583287A (zh) * 2006-12-20 2009-11-18 奇华顿荷兰服务有限责任公司 N-取代-对薄荷烷-3-甲酰胺及其用途
GB0704163D0 (en) 2007-03-02 2007-04-11 Quest Int Serv Bv Compositions comprising a physiological coolant
CN101677930A (zh) 2007-05-23 2010-03-24 吉万奥丹股份有限公司 用作清凉剂的丁酮衍生物
CN101883499A (zh) 2007-11-29 2010-11-10 吉百利亚当斯美国有限责任公司 具有活性物的多区咀嚼型胶基糖
US8377422B2 (en) 2007-12-07 2013-02-19 Givaudan S.A. Carboxamide derivatives having cooling properties
US20100297038A1 (en) * 2008-01-17 2010-11-25 Givaudan S.A. Benzimidazole Derivatives And Their Use As Cooling Agents
MX345970B (es) 2008-02-27 2017-02-28 Intercontinental Great Brands Llc Confiteria de regiones multiples.
CN102438462B (zh) 2008-05-02 2014-09-10 洲际大品牌有限责任公司 多层不含食糖的甘露糖醇糖食及其制作方法
WO2010085623A1 (en) 2009-01-22 2010-07-29 Cadbury Adams Usa, Llc Confectionery processing
US8487130B2 (en) * 2009-04-27 2013-07-16 International Flavors & Fragrances Inc. Menthylcarboxamides and their use as cooling agents
US7923577B2 (en) * 2009-04-27 2011-04-12 International Flavors & Fragrances Inc. Menthylcarboxamides and their use as cooling agents
WO2010128026A2 (en) 2009-05-05 2010-11-11 Givaudan Sa Organic compounds
MX2012004126A (es) 2009-10-08 2012-07-20 Kraft Foods Global Brands Llc Metodos y aparato para goma y caramelo en capas co-extrudido.
EP2316279B1 (en) 2009-10-30 2013-10-09 Intercontinental Great Brands LLC Sugar free confectionery; methods of making same; and use in preparing multilayered confectionery.
US20130052307A1 (en) 2009-12-21 2013-02-28 Cesar Carlos Elejalde Particulate coating compositions, coated confectionery, and methods of making the same
JP5684906B2 (ja) 2010-06-25 2015-03-18 インターコンチネンタル グレート ブランズ エルエルシー 親水コロイドを有するチューインガムからの親油性成分の高められた放出
JP5989009B2 (ja) 2011-02-14 2016-09-07 インターコンチネンタル グレート ブランズ エルエルシー 複数のフレーバーおよび複数の食感を有する菓子類
EP2677878B1 (en) 2011-02-23 2016-02-17 Intercontinental Great Brands LLC Flavor pre-blends for chewing gum, methods of making flavor pre-blends and chewing gum compositions thereof
GB201103103D0 (en) 2011-02-23 2011-04-06 Givaudan Sa Organic compounds
EP2683251B1 (en) 2011-03-11 2021-08-25 Intercontinental Great Brands LLC Method of forming multilayer confectionery
PL3536161T3 (pl) 2011-07-21 2025-12-15 Perfetti Van Melle Benelux B.V. Zaawansowane formowanie i chłodzenie gumy
JP2013195289A (ja) 2012-03-21 2013-09-30 Takasago Internatl Corp 感覚刺激成分の評価方法
DK3443847T3 (da) 2012-06-19 2025-09-29 Perfetti Van Melle Benelux B V Bulkpakket, uovertrukket tyggegummi
MX2015002312A (es) 2012-08-22 2015-06-23 Intercontinental Great Brands Llc Composiciones de goma de mascar y metodos para su preparacion.
WO2014128566A2 (en) 2013-02-21 2014-08-28 Mondelez International Chewing gum and methods of making thereof field
RU2015134216A (ru) 2013-03-29 2017-05-11 Интерконтинентал Грейт Брендс Ллк Леденец с начинкой из прозрачной просвечивающейся жидкости; способ его получения; не содержащая сахара жидкая пищевая композиция и ее применение
US20160100606A1 (en) 2013-05-31 2016-04-14 Intercontinental Great Brands Llc Chewing gum with hard, amorphous inclusions; and methods of making thereof
WO2015051056A1 (en) 2013-10-02 2015-04-09 Intercontinental Great Brands Llc Particulate coated chewing gum and confectionery; and methods of making the same
EP3110259A2 (en) 2014-02-28 2017-01-04 Intercontinental Great Brands LLC Coating for edible cores; system and process of coating; and coated products prepared therefrom
ES3076044T3 (en) 2014-03-03 2026-08-11 Perfetti Van Melle Benelux B V Method for manufacturing a comestible
RU2016138746A (ru) 2014-04-23 2018-05-24 Дзе Проктер Энд Гэмбл Компани Циклогексанкарбоксамид с охлаждающими свойствами
MX2016014941A (es) 2014-05-15 2017-04-11 Intercontinental Great Brands Llc Goma de mascar multitexturada y metodos para su fabricacion.
BR112018006471B1 (pt) 2015-10-01 2024-02-27 Senomyx, Inc Composto, composição, método de modular o membro de melastina do canal potencial do receptor transitório 8 (trpm8), método de modular a sensação de resfrescância de uma composição e método de induzir uma sensação de refrescância em um ser humano ou animal
US11236042B2 (en) 2017-01-10 2022-02-01 Takasago International Corporation Methylmenthol derivative and cool-sensation imparter composition containing same
MX2019008796A (es) 2017-02-06 2019-09-26 Intercontinental Great Brands Llc Golosina de textura doble; y metodos para elaborarla.
DK3850950T3 (da) 2017-06-05 2024-01-15 Perfetti Van Melle Benelux B V Tyggegummisammensætninger og fremgangsmåder til fremstilling deraf
CN110944516A (zh) 2017-08-18 2020-03-31 洲际大品牌有限责任公司 咀嚼型胶基糖组合物及其制备方法
JP7157072B2 (ja) 2017-10-16 2022-10-19 高砂香料工業株式会社 2,2,6-トリメチルシクロヘキサンカルボン酸誘導体を含有する冷感剤組成物
WO2020033669A1 (en) 2018-08-10 2020-02-13 Firmenich Incorporated Antagonists of t2r54 and compositions and uses thereof
WO2020086377A1 (en) 2018-10-26 2020-04-30 Intercontinental Great Brands Llc Center-filled confectionery product; coated product; and methods of making
EP4013233B1 (en) 2019-08-14 2024-10-02 Intercontinental Great Brands LLC Confectionery chip product and methods of making the same
US20230363407A1 (en) 2020-10-09 2023-11-16 Intercontinental Great Brands Llc Unwrapped hard candy product; isomalt confectionery; method of making and use thereof
CN115872881B (zh) * 2022-11-14 2025-02-14 云南中烟工业有限责任公司 一种薄荷醇胺类化合物的合成方法及其在卷烟中的应用
JP2026506814A (ja) 2023-03-01 2026-02-26 ペルフェッティ ヴァン メレ ベネルクス ベー.フェー. 歯を白くするチューインガム、及びそれを作製する方法
GB202303792D0 (en) 2023-03-15 2023-04-26 Givaudan Sa Cosmetic composition
CN122094568A (zh) 2023-08-10 2026-05-26 不凡帝范梅勒比荷卢公司 包括纤维的咀嚼型胶基糖、其制备方法及其使用方法
WO2026132198A1 (en) 2024-12-20 2026-06-25 Givaudan Sa Oral care compositions

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CN100582089C (zh) * 2003-11-21 2010-01-20 吉万奥丹股份有限公司 N-取代的对-薄荷烷甲酰胺

Also Published As

Publication number Publication date
CN101184470A (zh) 2008-05-21
KR20080020609A (ko) 2008-03-05
EP1885327A1 (en) 2008-02-13
JP2009501132A (ja) 2009-01-15
WO2006125334A1 (en) 2006-11-30
US20090105237A1 (en) 2009-04-23
MX2007014456A (es) 2008-02-07

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: NAO APRESENTADA A GUIA DE CUMPRIMENTO DE EXIGENCIA. REFERENTE A 6A ANUIDADE.

B15K Others concerning applications: alteration of classification

Ipc: C07C 237/42 (2006.01), A23G 3/34 (2006.01), A23G 4