BRPI0701826A - proteìnas da teia de aranha nephilengys cruentata, avicularia juruensis e parawixia bistriata isoladas da biodiversidade brasileira - Google Patents
proteìnas da teia de aranha nephilengys cruentata, avicularia juruensis e parawixia bistriata isoladas da biodiversidade brasileiraInfo
- Publication number
- BRPI0701826A BRPI0701826A BRPI0701826-6A BRPI0701826A BRPI0701826A BR PI0701826 A BRPI0701826 A BR PI0701826A BR PI0701826 A BRPI0701826 A BR PI0701826A BR PI0701826 A BRPI0701826 A BR PI0701826A
- Authority
- BR
- Brazil
- Prior art keywords
- present
- juruensis
- spider web
- bistriata
- avicularia
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 9
- 102000004169 proteins and genes Human genes 0.000 title abstract 6
- 241000175331 Avicularia juruensis Species 0.000 title abstract 2
- 241000742192 Nephilengys cruentata Species 0.000 title abstract 2
- 241001216760 Parawixia bistriata Species 0.000 title 1
- 239000013604 expression vector Substances 0.000 abstract 3
- 241000239290 Araneae Species 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 241000452926 Avicularia Species 0.000 abstract 1
- 241001216761 Parawixia Species 0.000 abstract 1
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 abstract 1
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 abstract 1
- 229920001872 Spider silk Polymers 0.000 abstract 1
- 238000012512 characterization method Methods 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
- C07K14/43518—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from spiders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Insects & Arthropods (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
PROTEìNAS DA TEIA DE ARANHA NEPHILENGYS CRUENTATA, AVICULARIA JURUENSIS E PARAWIXIA BISTRIATA ISOLADAS DA BIODIVERSIDADE BRASILEIRA. A presente invenção está relacionada com moléculas isoladas de ácido nucleico que codificam proteínas da teia de aranha ou um fragmentos das mesmas ou outras derivações das mesmas A invenção ainda discorre sobre um gene quimérico e um vetor de expressão contendo a molécula isolada de ácido nucleico que codifica para a proteína da teia de aranha de Nephilengv critentata, Avicularia juruensis e Parawix,a bistriata. Uma outra concretização da presente invenção são células transformadas contendo o gene quimérico ou o vetor de expressão da presente invenção. Ainda uma outra concretização da presente invenção diz respeito a um método de obtenção de orgamsmos geneticamente modificados contendo genes quiméricos ou vetores de expressão inventivos e a um método de obtenção de proteínas recombínantes da seda das aranhas Ncphilcngy crucutata, Ai 'icularia juruensis e Paraw,x,a bístriata Finalmente, a invenção descreve produtos, tais como biofilamentos e composições, utilizando-se da proteína recombínante da presente invenção. A descoberta de novas proteínas da seda de aranhas, bem como sua caracterização e expressão em diferentes sistemas heteíólogos será de grande utilidade para inúmeras áreas, 2omo a médica e industrial.
Priority Applications (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BRPI0701826-6A BRPI0701826B1 (pt) | 2007-03-16 | 2007-03-16 | proteínas da teia de aranha nephilengys cruentata, avicularia juruensis e parawixia bistriata isoladas da biodiversidade brasileira |
| US12/531,664 US20100311645A1 (en) | 2007-03-16 | 2008-03-13 | Proteins from the webs of nephilengys cruentata, avicularia juruensis and parawixia bistriata spiders isolated from brazilian biodiversity |
| CN201711245428.2A CN108218972B (zh) | 2007-03-16 | 2008-03-13 | 来自Nephilengys Cruentata蜘蛛的网的蛋白 |
| CN200880015224A CN101679975A (zh) | 2007-03-16 | 2008-03-13 | 来自Nephilengys Cruentata蜘蛛、黄带粉趾食鸟蛛和Parawixia Bistriata蜘蛛的网的蛋白 |
| EP18178559.3A EP3434768A1 (en) | 2007-03-16 | 2008-03-13 | Proteins from the webs of nephilengys cruentata, avicularia juruensis and parawixia bistriata spiders |
| PCT/BR2008/000072 WO2008113145A1 (en) | 2007-03-16 | 2008-03-13 | Proteins from the webs of nephilengys cruentata, avicularia juruensis and parawixia bistriata spiders |
| EP08714519A EP2126076A4 (en) | 2007-03-16 | 2008-03-13 | PROTEINS FROM THE NETWORKS OF SPIDERS NEPHILENGYS CRUENTATA, AVICULARIA JURUENSIS AND PARAWIXIA BISTRIATA |
| ARP080101091A AR065777A1 (es) | 2007-03-16 | 2008-03-14 | Proteinas de la telarana de nephilengys cruentata, avicularia juruensis y parawixia bistriata aisladas de la biodiversidad brasilera |
| US13/749,601 US10889624B2 (en) | 2007-03-16 | 2013-01-24 | Proteins from the webs of nephilengys cruentata, a vicularia juruensis and parawixia bistriata spiders isolated from brazilian biodiversity |
| HK18116693.6A HK1257458B (en) | 2007-03-16 | 2018-12-28 | Proteins from the webs of nephilengys cruentata spiders |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BRPI0701826-6A BRPI0701826B1 (pt) | 2007-03-16 | 2007-03-16 | proteínas da teia de aranha nephilengys cruentata, avicularia juruensis e parawixia bistriata isoladas da biodiversidade brasileira |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BRPI0701826A true BRPI0701826A (pt) | 2008-11-04 |
| BRPI0701826B1 BRPI0701826B1 (pt) | 2021-02-17 |
Family
ID=39765310
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0701826-6A BRPI0701826B1 (pt) | 2007-03-16 | 2007-03-16 | proteínas da teia de aranha nephilengys cruentata, avicularia juruensis e parawixia bistriata isoladas da biodiversidade brasileira |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20100311645A1 (pt) |
| EP (2) | EP3434768A1 (pt) |
| CN (2) | CN108218972B (pt) |
| AR (1) | AR065777A1 (pt) |
| BR (1) | BRPI0701826B1 (pt) |
| WO (1) | WO2008113145A1 (pt) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8642734B2 (en) | 2009-04-22 | 2014-02-04 | Spiber Technologies Ab | Method of producing polymers of spider silk proteins |
| EP2547771B8 (en) | 2010-03-18 | 2017-07-19 | Spiber Technologies AB | Production of proteins and polypeptides |
| KR101926286B1 (ko) * | 2010-09-28 | 2018-12-10 | 유니버시티 오브 노트르 담 듀락 | 키메라 거미 실크 및 이의 용도 |
| BRPI1102841B1 (pt) * | 2011-06-08 | 2018-11-21 | Empresa Brasileira De Pesquisa Agropecuaria Embrapa | MUTANTES DE INIBIDORES DE ALFA AMILASES ISOLADOS DE Phaseolus vulgaris COM PROPRIEDADES DE CONTROLAR INSETOS-PRAGA, COMPOSIÇÕES CONTENDO TAIS MUTANTES E MÉTODOS DE OBTENÇÃODOS MESMOS E DE LINHAGENS TRANSGÊNICAS |
| WO2014026345A1 (zh) * | 2012-08-16 | 2014-02-20 | 东华大学 | 一种提取大腹园蛛MiSp全长基因及全长基因表达的方法 |
| WO2017115005A1 (en) | 2015-12-29 | 2017-07-06 | Teknologian Tutkimuskeskus Vtt Oy | Production of fusion proteins in trichoderma |
| CN105777885B (zh) * | 2016-04-11 | 2019-07-09 | 中南大学 | 一种新疆穴居狼蛛Lycosa singoriensis抗菌肽及应用 |
| CN107805283B (zh) * | 2017-11-10 | 2021-01-15 | 井冈山大学 | 一种拟蛛丝蛋白及其生物合成方法 |
| CN112654247B (zh) | 2018-08-17 | 2022-11-04 | 阿姆西尔克有限公司 | 结构多肽在植物包衣中的用途 |
| CA3127177A1 (en) * | 2019-01-31 | 2020-08-06 | Spiber Inc. | Method for producing recombinant protein |
| CN110317252B (zh) * | 2019-06-10 | 2021-01-26 | 华南师范大学 | 云斑蛛牵引丝性能及其丝蛋白基因序列 |
| WO2020262602A1 (ja) * | 2019-06-28 | 2020-12-30 | Ｓｐｉｂｅｒ株式会社 | 合成皮革及びその製造方法、並びに合成皮革用接着剤 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US576677A (en) | 1897-02-09 | Abel ken worthy | ||
| AU2811889A (en) | 1987-10-20 | 1989-05-23 | Plant Genetic Systems N.V. | A process for the production of biologically active peptide via the expression of modified storage seed protein genes in transgenic plants |
| GB8810120D0 (en) | 1988-04-28 | 1988-06-02 | Plant Genetic Systems Nv | Transgenic nuclear male sterile plants |
| AU7691191A (en) | 1990-04-19 | 1991-11-11 | United States Of America, As Represented By The Secretary Of The Army, The | Recombinant spider silk proteins through genetic engineering |
| US5989894A (en) | 1990-04-20 | 1999-11-23 | University Of Wyoming | Isolated DNA coding for spider silk protein, a replicable vector and a transformed cell containing the DNA |
| EP0573443B1 (en) | 1991-02-08 | 2006-07-05 | Bayer BioScience N.V. | Stamen-specific promoters from rice |
| EP0707645B1 (en) | 1993-06-15 | 2003-11-05 | E.I. Du Pont De Nemours And Company | Novel, recombinantly produced spider silk analogs |
| US5733771A (en) | 1994-03-14 | 1998-03-31 | University Of Wyoming | cDNAs encoding minor ampullate spider silk proteins |
| HUP9802535A3 (en) | 1995-10-06 | 2001-04-28 | Plant Genetic Systems Nv | Seed shattering |
| US5994099A (en) | 1997-12-31 | 1999-11-30 | The University Of Wyoming | Extremely elastic spider silk protein and DNA coding therefor |
| FR2774588B1 (fr) | 1998-02-11 | 2000-05-05 | Oreal | Composition cosmetique ou dermatologique contenant au moins une proteine de soie d'arachnides naturelle, recombinante ou un analogue |
| US7157615B2 (en) | 1998-03-17 | 2007-01-02 | Nexia Biotechnologies, Inc. | Production of biofilaments in transgenic animals |
| US7029917B2 (en) | 1998-05-01 | 2006-04-18 | The Regents Of The University Of California | Nucleic acids that control seed and fruit development in plants |
| US6608242B1 (en) | 2000-05-25 | 2003-08-19 | E. I. Du Pont De Nemours And Company | Production of silk-like proteins in plants |
| EP1287139B1 (de) | 2000-06-09 | 2010-08-25 | Leibniz-Institut für Pflanzengenetik und Kulturpflanzenforschung (IPK) | Synthetische spinnenseidenproteine und deren expression in transgenen pflanzen |
| US6412261B1 (en) | 2001-03-21 | 2002-07-02 | The Forman School | Method of reinforcing a fiber with spider silk |
| AU2002312426A1 (en) | 2001-06-06 | 2002-12-16 | University Of Wyoming | Expression of spider silk proteins in higher plants |
| EP1427742A1 (en) | 2001-08-29 | 2004-06-16 | University of Wyoming | Spider silk protein encoding nucleic acids, polypeptides, antibodies and method of use thereof |
| CN1380418A (zh) | 2002-01-24 | 2002-11-20 | 中国科学院遗传与发育生物学研究所 | 蜘蛛丝基因的棉纤维细胞表达载体质粒 |
| EP1490489B1 (en) | 2002-03-14 | 2010-06-02 | Commonwealth Scientific and Industrial Research Organisation | Methods and means for monitoring and modulating gene silencing |
| US20040102608A1 (en) * | 2002-05-13 | 2004-05-27 | Cornell Research Foundation, Inc. | Multiblock copolymers having improved mechanical properties |
| GB0218977D0 (en) | 2002-08-15 | 2002-09-25 | Univ York | Polypeptide |
| CA2573780C (en) * | 2004-07-22 | 2013-11-19 | Technische Universitaet Muenchen | Recombinant spider silk proteins |
-
2007
- 2007-03-16 BR BRPI0701826-6A patent/BRPI0701826B1/pt active IP Right Grant
-
2008
- 2008-03-13 CN CN201711245428.2A patent/CN108218972B/zh active Active
- 2008-03-13 EP EP18178559.3A patent/EP3434768A1/en active Pending
- 2008-03-13 US US12/531,664 patent/US20100311645A1/en not_active Abandoned
- 2008-03-13 EP EP08714519A patent/EP2126076A4/en not_active Ceased
- 2008-03-13 CN CN200880015224A patent/CN101679975A/zh active Pending
- 2008-03-13 WO PCT/BR2008/000072 patent/WO2008113145A1/en not_active Ceased
- 2008-03-14 AR ARP080101091A patent/AR065777A1/es not_active Application Discontinuation
-
2013
- 2013-01-24 US US13/749,601 patent/US10889624B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| HK1257458A1 (zh) | 2019-10-18 |
| US10889624B2 (en) | 2021-01-12 |
| US20140206851A1 (en) | 2014-07-24 |
| US20100311645A1 (en) | 2010-12-09 |
| WO2008113145A8 (en) | 2009-11-26 |
| WO2008113145A1 (en) | 2008-09-25 |
| EP2126076A4 (en) | 2010-06-16 |
| EP2126076A1 (en) | 2009-12-02 |
| AR065777A1 (es) | 2009-07-01 |
| CN101679975A (zh) | 2010-03-24 |
| EP3434768A1 (en) | 2019-01-30 |
| CN108218972A (zh) | 2018-06-29 |
| CN108218972B (zh) | 2021-10-15 |
| BRPI0701826B1 (pt) | 2021-02-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BRPI0701826A (pt) | proteìnas da teia de aranha nephilengys cruentata, avicularia juruensis e parawixia bistriata isoladas da biodiversidade brasileira | |
| Baumgartner et al. | Small proteins in cyanobacteria provide a paradigm for the functional analysis of the bacterial micro-proteome | |
| Pesavento et al. | The global repressor FliZ antagonizes gene expression by σ S-containing RNA polymerase due to overlapping DNA binding specificity | |
| BR112012029588A2 (pt) | materiais biológicas relacionados a her3. | |
| Gimpel et al. | SR1—a small RNA with two remarkably conserved functions | |
| MX2019002345A (es) | Moleculas artificiales de acido nucleico para la expresion mejorada de proteina o peptido. | |
| BRPI0914780B8 (pt) | Molécula de ácido nucleico isolada, vetor, célula hospedeira, composição, e métodos para o controle de uma população de pragas, matar uma praga proteção de uma planta de uma praga e produção de um polipeptídeo com atividade pesticida | |
| BRPI0806578A8 (pt) | Promotores de lactococcus e usos dos mesmos | |
| BR112017018728A2 (pt) | sistema de vetor para expressar a sequência de codificação de um gene de interesse em uma célula, célula hospedeira, composição farmacêutica, método para tratar e/ou prevenir uma patologia ou doença, uso de uma sequência de nucleotídeo de um sinal de degradação em um sistema de vetor e método para diminuir a expressão de uma proteína na forma truncada | |
| BR112014022166A2 (pt) | gene da delta-endotoxina axmi345 e métodos para a sua utilização | |
| BR112012020705B8 (pt) | Molécula de ácido nucleico recombinante, vetor, célula hospedeira microbiana, polipeptídeo recombinante com atividade pesticida, composição, bem como métodos para o controle de uma população de pragas de lepidópteros, para matar uma praga de lepidóptero, para a produção de um polipeptídeo com atividade pesticida, para a proteção de uma planta de uma praga, e para aumentar o rendimento em uma planta | |
| BRPI0515902A (pt) | célula de planta, planta, semente, molécula de ácido nucleico isolada, construto de ácido nucleico, vetor, célula hospedeira, proteìna relacionada à tensão isolada, métodos de produção de uma planta transgênica e de modificação de toleráncia à tensão de uma planta, e, usos de um ácido nucleico que codifica srp e de toleráncia e/ou resistência aumentada à tensão ambiental e/ou ácido nucleico | |
| WO2011106766A3 (en) | Modified proteins and methods of making and using same | |
| BR112014001909A2 (pt) | gene da toxina axmi270 e métodos para a sua utilização | |
| EA201071323A1 (ru) | Axmi-115, axmi-113, axmi-005, axmi-163, axmi-184 инсектицидные белки и способы их применения | |
| Srivastava et al. | Genetic regulation of spy gene expression in Escherichia coli in the presence of protein unfolding agent ethanol | |
| BR112015021651A2 (pt) | Molécula de ácido nucleico recombinante, cassete de expressão, célula hospedeira de bactéria, polipeptídeo recombinante, composição e métodos para aplicação dos mesmos | |
| MX2019009045A (es) | Nuevas luciferasas y metodos para su uso. | |
| BR112014022034A2 (pt) | gene da toxina axmi335 de bacillus thuringiensis e métodos para a sua utilização | |
| Weigel | Planning, evaluating and vetting receptor signaling studies to assess hyaluronan size-dependence and specificity | |
| Lu et al. | Dynamics of epitranscriptomes uncover translational reprogramming directed by ac4C in rice during pathogen infection | |
| Fitzgerald et al. | Re-engineering cellular physiology by rewiring high-level global regulatory genes | |
| DK1994149T3 (da) | Nye fluorescerende proteiner og fremgangsmåder til anvendelse deraf | |
| EA201071400A1 (ru) | Новый ген bacillus thuringiensis с активностью против lepidopteran (чешуекрылых) | |
| ATE500265T1 (de) | Synthetische mecp2-sequenz für die proteinersatztherapie |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B03A | Publication of a patent application or of a certificate of addition of invention [chapter 3.1 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B25C | Requirement related to requested transfer of rights |
Owner name: EMBRAPA - EMPRESA BRASILEIRA DE PESQUISA AGROPECUA Free format text: A FIM DE ATENDER A TRANSFERENCIA SOLICITADA ATRAVES DA PETICAO NO 12070000768-DF, DE 19/07/2007, E NECESSARIO APRESENTAR DOCUMENTO DE CESSAO ASSINADO PELOS REPRESENTANTES DAS PARTES ENVOLVIDAS E SUAS FIRMAS RECONHECIDAS. ALEM DISSO, E MISTER INDICAR, NO DOCUMENTO DE CESSAO, O NUMERO DO DEPOSITO. POR FIM, A CEDENTE DEVE APRESENTAR DOCUMENTO QUE COMPROVE A EXTENSAO DOS PODERES DE SEU REPRESENTANTE PARA QUE SE VERIFIQUE SE ELE ESTA APTO A ALIENAR BENS. |
|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B08E | Application fees: payment of additional fee required [chapter 8.5 patent gazette] | ||
| B08H | Application fees: decision cancelled [chapter 8.8 patent gazette] | ||
| B25B | Requested transfer of rights rejected |
Owner name: EMBRAPA - EMPRESA BRASILEIRA DE PESQUISA AGROPECUA |
|
| B07G | Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette] |
Free format text: NOTIFICACAO DE DEVOLUCAO DO PEDIDO POR NAO SE ENQUADRAR NO ART. 229-C DA LPI. |
|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 17/02/2021, OBSERVADAS AS CONDICOES LEGAIS. |