BRPI0710689A2 - método para preparação de uma vacina de aiv feita de planta e a referida vacina - Google Patents

método para preparação de uma vacina de aiv feita de planta e a referida vacina Download PDF

Info

Publication number
BRPI0710689A2
BRPI0710689A2 BRPI0710689-0A BRPI0710689A BRPI0710689A2 BR PI0710689 A2 BRPI0710689 A2 BR PI0710689A2 BR PI0710689 A BRPI0710689 A BR PI0710689A BR PI0710689 A2 BRPI0710689 A2 BR PI0710689A2
Authority
BR
Brazil
Prior art keywords
vaccine
aiv
plant
preparing
vaccines
Prior art date
Application number
BRPI0710689-0A
Other languages
English (en)
Inventor
Robert Webb Steven
J. Henry Matthew
Original Assignee
Dow Agrosciences Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Agrosciences Llc filed Critical Dow Agrosciences Llc
Publication of BRPI0710689A2 publication Critical patent/BRPI0710689A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C12N15/8258—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon for the production of oral vaccines (antigens) or immunoglobulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plant Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Biochemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

MéTODO PARA PREPARAçãO DE UMA VACINA DE AIV FEITA DE PLANTA E A REFERIDA VACINA. A presente invenção refere-se a vacinas para influenza e particularmente vacinas para influenza da ave (AIV). A invenção inclui métodos para preparação de células de planta transgênica para expressar polipeptídeos de HA1 conhecidos tendo homologias especificadas que são usados para preparar composições de vacina e métodos para indução de imunidade protetora em um individuo, animal, mamífero ou ser humano.
BRPI0710689-0A 2006-04-21 2007-04-20 método para preparação de uma vacina de aiv feita de planta e a referida vacina BRPI0710689A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US79380406P 2006-04-21 2006-04-21
US60/793,804 2006-04-21
PCT/US2007/067069 WO2008060669A2 (en) 2006-04-21 2007-04-20 Vaccine for avian influenza and methods of use

Publications (1)

Publication Number Publication Date
BRPI0710689A2 true BRPI0710689A2 (pt) 2012-02-22

Family

ID=39402309

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0710689-0A BRPI0710689A2 (pt) 2006-04-21 2007-04-20 método para preparação de uma vacina de aiv feita de planta e a referida vacina

Country Status (9)

Country Link
US (1) US7993655B2 (pt)
EP (1) EP2010210A4 (pt)
JP (1) JP2009535306A (pt)
KR (1) KR20080109094A (pt)
CN (1) CN101578111A (pt)
AR (1) AR060565A1 (pt)
BR (1) BRPI0710689A2 (pt)
CA (1) CA2650091A1 (pt)
WO (1) WO2008060669A2 (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2029167A4 (en) * 2006-06-16 2010-06-16 Dow Agrosciences Llc NEW DNA SEQUENCES, VECTORS AND PROTEINS OF BIRD FLUID HEMOGGLUTININE
WO2008140557A2 (en) 2006-10-24 2008-11-20 Samuel Bogoch A method of predicting influenza outbreaks
EP2594578A1 (en) 2007-05-30 2013-05-22 Samuel Bogoch Replikin peptides directed against pathogenic infections of invertebrates in aquaculture
CA2615372A1 (en) 2007-07-13 2009-01-13 Marc-Andre D'aoust Influenza virus-like particles (vlps) comprising hemagglutinin
EP2610345B1 (en) 2007-11-27 2015-08-19 Medicago Inc. Recombinant influenza virus-like particles (VLPS) produced in transgenic plants expressing hemagglutinin
EA034733B1 (ru) * 2008-01-21 2020-03-13 Медикаго Инк. Нуклеиновая кислота для увеличенной экспрессии гемагглютинина вируса гриппа в растении и ее применение
DK2294202T3 (en) 2008-07-08 2015-08-31 Medicago Inc SOLUBLE RECOMBINANT INFLUENZA ANTIGENES
US9233148B2 (en) 2009-01-09 2016-01-12 Samuel Bogoch Replikin-based compounds for prevention and treatment of influenza and methods of differentiating infectivity and lethality in influenza
SG10201401532PA (en) * 2009-04-23 2014-08-28 Samuel Bogoch Replikin-sequences for preventing/treating influenza and determining infectivity/lethality
DK2445928T3 (en) 2009-06-24 2018-05-28 Medicago Inc CHEMICAL INFLUENZA VIRUS-LIKE PARTICLES INCLUDING HEMAGGLUTIN
ES2642631T3 (es) 2009-09-22 2017-11-17 Medicago Inc. Método de preparación de VLP derivadas de plantas
CN102665422B (zh) * 2009-12-23 2015-01-28 疫苗基因集团 通过口服施用重组乳酸乳球菌微型胶囊的免疫保护方法
CN102869379B (zh) 2010-04-30 2015-04-15 淡马锡生命科学研究院有限公司 H5n1谱系的通用疫苗
TWI620816B (zh) 2011-03-23 2018-04-11 苜蓿股份有限公司 植物衍生蛋白回收方法
WO2013013075A2 (en) 2011-07-20 2013-01-24 Samuel Bogoch Peptides shared among lethal cancers and therapeutic compositions comprising said peptides
AU2013204906B2 (en) * 2012-03-12 2016-01-07 Advanced Bioadjuvants, Llc Adjuvant and vaccine compositions
US9493844B2 (en) 2012-12-13 2016-11-15 Dow Agrosciences Llc DNA detection methods for site specific nuclease activity

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5173410A (en) 1984-02-15 1992-12-22 Lubrizol Genetics Inc. Transfer vector
US4885248A (en) 1984-02-15 1989-12-05 Lubrizol Genetics, Inc. Transfer vector
CA1288073C (en) 1985-03-07 1991-08-27 Paul G. Ahlquist Rna transformation vector
ES2060646T3 (es) 1987-02-09 1994-12-01 Lubrizol Genetics Inc Virus rna hibrido.
CA2071943C (en) 1989-12-22 2007-04-24 Joan Tellefsen Odell Site-specific recombination of dna in plant cells
US5384253A (en) 1990-12-28 1995-01-24 Dekalb Genetics Corporation Genetic transformation of maize cells by electroporation of cells pretreated with pectin degrading enzymes
JPH07200893A (ja) 1993-12-27 1995-08-04 Toshiba Corp 自動精算機
GB9615794D0 (en) * 1996-07-26 1996-09-04 Medical Res Council Mutant herpes simplex virus strains and uses thereof
US5916879A (en) * 1996-11-12 1999-06-29 St. Jude Children's Research Hospital DNA transcription unit vaccines that protect against avian influenza viruses and methods of use thereof
JP2000253876A (ja) * 1999-03-08 2000-09-19 Dnavec Research Inc センダイウイルスベクターを用いたワクチンおよびワクチンタンパク質
MXPA02010322A (es) * 2000-04-19 2004-09-10 Univ Johns Hopkins Metodos para la prevencion y tratamiento de trastornos gastrointestinales.
WO2002008386A2 (en) 2000-07-20 2002-01-31 The University Of Tennessee Research Corporation Materials and methods for the enhancement of effective root nodulation in legumes
DE10049587A1 (de) 2000-10-06 2002-05-02 Icon Genetics Ag Vektorsystem für Pflanzen
DE10061150A1 (de) 2000-12-08 2002-06-13 Icon Genetics Ag Verfahren und Vektoren zur Erzeugung von transgenen Pflanzen
DE10109354A1 (de) 2001-02-27 2002-09-05 Icon Genetics Ag Rekombinante virale Schaltersysteme
DE10121283B4 (de) 2001-04-30 2011-08-11 Icon Genetics GmbH, 80333 Verfahren und Vektoren zur Amplifikation oder Expression von gewünschten Nucleinsäuresequenzen in Pflanzen
US20030084482A1 (en) 2001-06-08 2003-05-01 Gerald Hall Production of proteins in plants
DE10129010A1 (de) 2001-06-13 2002-12-19 Icon Genetics Ag Verfahren und Vektoren zur Erzeugung von transgenen Pflanzen
DE10143205A1 (de) 2001-09-04 2003-03-20 Icon Genetics Ag Verfahren zur Proteinproduktion in Pflanzen
WO2002096192A2 (en) 2002-04-29 2002-12-05 Icon Genetics Ag Process of producing environmentally safe transgenic organisms
KR20060029214A (ko) * 2003-05-05 2006-04-05 다우 아그로사이언시즈 엘엘씨 이식 유전자 식물 세포들로부터 유래된 안정한 면역예방적및 치료적 조성물들 및 생산방법
DE602004028004D1 (de) * 2003-05-05 2010-08-19 Thompson Boyce Plant Res Vektoren und zellen zur herstellung von aus transgenen pflanzen gewonnenen immunprotektiven zusammensetzungen
WO2005018539A2 (en) 2003-06-16 2005-03-03 Medimmune Vaccines, Inc. Influenza hemagglutinin and neuraminidase variants
DK1682667T3 (da) 2003-11-10 2010-08-23 Icon Genetics Gmbh RNA-virus afledt plantekspressionssystem

Also Published As

Publication number Publication date
EP2010210A2 (en) 2009-01-07
CN101578111A (zh) 2009-11-11
US20090136532A1 (en) 2009-05-28
JP2009535306A (ja) 2009-10-01
EP2010210A4 (en) 2010-07-21
AR060565A1 (es) 2008-06-25
US7993655B2 (en) 2011-08-09
WO2008060669A2 (en) 2008-05-22
CA2650091A1 (en) 2008-05-22
WO2008060669A3 (en) 2009-05-07
KR20080109094A (ko) 2008-12-16

Similar Documents

Publication Publication Date Title
BRPI0710689A2 (pt) método para preparação de uma vacina de aiv feita de planta e a referida vacina
BRPI0410340A (pt) vetores e células para preparar composições imunoprotetoras derivadas de plantas transgênicas
MX2011000047A (es) Uso de factores de crecimiento recombinantes derivados de plantas en el cuidado de la piel.
MX2010012999A (es) Vacuna de vesícula de membrana externa nativa multivalente del meningococo, método para su fabricación y uso.
MX2018009917A (es) Vacuna contra el virus del zika.
AR059772A1 (es) Composiciones que incuyen hemaglutinina metodos de elaboracion y metodos de uso de las mismas
WO2007126816A3 (en) Methods and compositions for vaccination of poultry
BR112012020839A2 (pt) vacinas para uso na profilaxe e tratamento de doença de vírus da influenza
AR061930A1 (es) Mimeticuerpos de glp-1 humanos, composiciones, metodos y usos
BR112014026744A8 (pt) anticorpo isolado ou fragmento de anticorpo, composição de anticorpo ou composição de fragmento de anticorpo, uso de modulação imune, uso de pelo menos uma composição de anticorpo ou fragmento de anticorpo, dispositivo médico, formulação, kit, artigo de fabricação para uso farmacêutico humano, método para produzir um anticorpo ou fragmento, animal ou planta transgênica, e, anticorpo ou porção ou variante especificada.
BRPI1015053A2 (pt) partículas similares a vírus da influenza quiméricas compreendendo hemaglutinina
MX2008009929A (es) Vacuna a base de levadura para inducir una respuesta inmune.
CO6331297A2 (es) Composiciones adyuvantes novedosas
MX2009006178A (es) Vacuna contra salmonela.
CY1120430T1 (el) Ανασυνδυασμενες cdv συνθεσεις και χρησεις αυτων
AR068871A1 (es) Combinacion de lipo - quitooligosacaridos y flavonoides para mejorar el crecimiento y el rendimiento de las plantas
PE20151588A1 (es) Vacuna contra el virus del dengue
BRPI0918806A2 (pt) composição compreendendo quitosana para administração ocular de vaninas em aves
BRPI0607551A2 (pt) vacinas de combinação de helicobacter e circovìrus porcino e métodos de uso
AU2011280259A8 (en) Influenza vaccine
CO6440541A2 (es) Virus de diarrea viral bovina con una proteina erns modificada
BR112023019301A2 (pt) Formulações de vacina de coronavírus
PL2211884T3 (pl) Hydrolizaty uzyskiwane z ekstraktów roślinnych oraz zawierający je środek antybakteryjny
MX2022012647A (es) Composiciones que comprenden tres proteinas de fusion de ospa para uso medico.
BR112017028212A2 (pt) vacinação concomitante contra dengue e febre amarela

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06H Technical and formal requirements: requirement cancelled [chapter 6.8 patent gazette]

Free format text: REF. A RPI NO 2155 DE 24/04/2012. ANULACAO DA EXIGENCIA 6.6 POR TER SIDO INDEVIDA. REQUERENTE NAO APRESENTOU RESPOSTA A EXIGENCIA CONFORME DISPOE A RESOLUCAO 207 DE 24/04/2009, ENTRETANTO, A RESPOSTA CONSTA NO FORMULARIO DE DEPOSITO.

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2256 DE 01/04/2014.