BRPI0711346A2 - método para detectar um alvo em uma amostra suspeita de conter o alvo, e, uso de um magneto - Google Patents
método para detectar um alvo em uma amostra suspeita de conter o alvo, e, uso de um magneto Download PDFInfo
- Publication number
- BRPI0711346A2 BRPI0711346A2 BRPI0711346-3A BRPI0711346A BRPI0711346A2 BR PI0711346 A2 BRPI0711346 A2 BR PI0711346A2 BR PI0711346 A BRPI0711346 A BR PI0711346A BR PI0711346 A2 BRPI0711346 A2 BR PI0711346A2
- Authority
- BR
- Brazil
- Prior art keywords
- target
- detecting
- sample suspected
- binding molecule
- magnet
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
- G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/72—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables
- G01N27/74—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids
- G01N27/745—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids for detecting magnetic beads used in biochemical assays
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2446/00—Magnetic particle immunoreagent carriers
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Electrochemistry (AREA)
- Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Abstract
MéTODO PARA DETECTAR UM ALVO EM UMA AMOSTRA SUSPEITA DE CONTER O ALVO, E, USO DE UM MAGNETO. O pedido se relaciona a um método para detectar um alvo em uma amostra suspeita de conter o alvo. O método compreende contatar a amostra e uma primeira molécula de ligação presa a uma partícula magnética com uma segunda molécula de ligação presa a um suporte sólido. A primeira molécula de ligação é capaz de se ligara a segunda molécula de ligação, e o alvo é capaz de interferir com este ligação. Força magnética é aplicada para trazer a partícula magnética nas proximidades do suporte sólido. O número de partículas magnéticas ligadas ao suporte sólido é detectado.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06113698 | 2006-05-09 | ||
| PCT/IB2007/051578 WO2007132373A1 (en) | 2006-05-09 | 2007-04-27 | Detection of target molecules in a sample by using a magnetic field |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BRPI0711346A2 true BRPI0711346A2 (pt) | 2011-08-30 |
| BRPI0711346A8 BRPI0711346A8 (pt) | 2015-10-06 |
Family
ID=38445621
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0711346A BRPI0711346A8 (pt) | 2006-05-09 | 2007-04-27 | Método para detectar um alvo em uma amostra suspeita de conter o alvo, e, uso de um magneto |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US10488408B2 (pt) |
| EP (1) | EP2027468B1 (pt) |
| JP (1) | JP5200003B2 (pt) |
| CN (1) | CN101438163B (pt) |
| AT (1) | ATE514086T1 (pt) |
| BR (1) | BRPI0711346A8 (pt) |
| RU (1) | RU2444736C2 (pt) |
| WO (1) | WO2007132373A1 (pt) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8618508B2 (en) | 2008-09-25 | 2013-12-31 | Koninklijke Philips N.V. | Detection system and method |
| BRPI0918101A2 (pt) | 2008-12-22 | 2015-11-24 | Koninkl Philips Electronics Nv | método para medir a troponina i em uma amostra, cartucho para ser utilizado em um dispositivo de ensaio e uso |
| JP6013912B2 (ja) * | 2009-07-30 | 2016-10-25 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | オリゴヌクレオチドプローブのセットならびにそれに関連する方法および使用 |
| WO2011034854A1 (en) * | 2009-09-19 | 2011-03-24 | Surgimed Biosciences, Inc. | Method and apparatus for automated cell transfer therapy and hair transplantation |
| GB201110272D0 (en) | 2011-06-17 | 2011-08-03 | Isis Innovation | Metod of detection by mass spectrometry |
| EP2726881A1 (en) * | 2011-06-28 | 2014-05-07 | Koninklijke Philips N.V. | Means for the examination of body fluids |
| WO2013102850A1 (en) | 2012-01-04 | 2013-07-11 | Insituto De Engenharia De Sistemas E Computadores Para Os Microsistemas E As Nanotecnologias | Monolithic device combining cmos with magnetoresistive sensors |
| CN104603611B (zh) * | 2012-09-04 | 2019-04-05 | 皇家飞利浦有限公司 | 传感器设备和采样方法 |
| RU2653145C2 (ru) | 2012-09-04 | 2018-05-07 | Конинклейке Филипс Н.В. | Измерительное устройство и способ отбора образцов |
| CN105579849B (zh) * | 2013-06-06 | 2019-02-22 | 微型照顾私人有限公司 | 在用于检测多聚靶分子的基于颗粒的测试中防止聚集的试剂、方法和设备 |
| CA2959741A1 (en) * | 2014-10-20 | 2016-04-28 | Christopher Gordon Atwood | Analyzing a sample with a construct comprising a fluorescent moiety and a magnetic moiety |
| US10261076B2 (en) * | 2015-10-02 | 2019-04-16 | The Board Of Trustees Of The Leland Stanford Junior University | Method for detecting small molecule analytes using magnetoresistant sensors |
| US12339233B2 (en) * | 2015-12-24 | 2025-06-24 | Siemens Healthineers Nederland B.V. | Optical detection of a substance in fluid |
| WO2018140719A1 (en) * | 2017-01-26 | 2018-08-02 | Confer Health, Inc. | Magnetic particle-based immunoassay and methods of using the same |
| WO2023057823A1 (en) * | 2021-10-10 | 2023-04-13 | Alipour Elias | Detecting an antigen of a virus using electrochemical analysis |
| EP4592678A1 (en) * | 2024-01-26 | 2025-07-30 | Technische Universität München | Method and device for detecting a concentration of at least one analyte in a sample |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL82873A0 (en) | 1987-06-15 | 1987-12-20 | Orgenics Ltd | Reversed competitive solid phase immunoassay for detecting single epitope analytes and kit therefor |
| US5445971A (en) * | 1992-03-20 | 1995-08-29 | Abbott Laboratories | Magnetically assisted binding assays using magnetically labeled binding members |
| US5635364A (en) * | 1992-03-27 | 1997-06-03 | Abbott Laboratories | Assay verification control for an automated analytical system |
| AU3972993A (en) | 1992-04-01 | 1993-11-08 | Regents Of The University Of California, The | Non-instrumented enzyme immunoassay: general method utilizing kinetic binding effects |
| WO1996007101A1 (en) * | 1994-08-31 | 1996-03-07 | First Medical, Inc. | Quantitative assays employing magnetizable particles for rate enhancement |
| US5660990A (en) * | 1995-08-18 | 1997-08-26 | Immunivest Corporation | Surface immobilization of magnetically collected materials |
| US6586193B2 (en) | 1996-04-25 | 2003-07-01 | Genicon Sciences Corporation | Analyte assay using particulate labels |
| JP2000510582A (ja) * | 1996-04-25 | 2000-08-15 | ゼニコン・サイエンシーズ・コーポレーション | 微粒子標識を使用した分析物アッセイ |
| FR2758884B1 (fr) * | 1997-01-30 | 1999-04-02 | Bio Merieux | Procede pour isoler, notamment detecter ou quantifier un analyte dans un milieu |
| US5981297A (en) * | 1997-02-05 | 1999-11-09 | The United States Of America As Represented By The Secretary Of The Navy | Biosensor using magnetically-detected label |
| DE19822123C2 (de) * | 1997-11-21 | 2003-02-06 | Meinhard Knoll | Verfahren und Vorrichtung zum Nachweis von Analyten |
| CA2327816A1 (en) * | 1998-04-09 | 1999-10-21 | Nycomed Imaging As | Use of particulate contrast agents in diagnostic imaging for studying physiological parameters |
| US6287765B1 (en) * | 1998-05-20 | 2001-09-11 | Molecular Machines, Inc. | Methods for detecting and identifying single molecules |
| CA2381732A1 (en) * | 1999-08-21 | 2001-03-01 | John S. Fox | High sensitivity biomolecule detection with magnetic particles |
| US6897015B2 (en) * | 2000-03-07 | 2005-05-24 | Bioforce Nanosciences, Inc. | Device and method of use for detection and characterization of pathogens and biological materials |
| RU2166751C1 (ru) | 2000-03-09 | 2001-05-10 | Никитин Петр Иванович | Способ анализа смеси биологических и/или химических компонентов с использованием магнитных частиц и устройство для его осуществления |
| US7241630B2 (en) * | 2000-04-10 | 2007-07-10 | Randox Laboratories, Ltd. | Paramagnetic particle detection |
| GB0124341D0 (en) | 2001-10-10 | 2001-11-28 | Randox Lab Ltd | Assay |
| US7432105B2 (en) * | 2002-08-27 | 2008-10-07 | Kimberly-Clark Worldwide, Inc. | Self-calibration system for a magnetic binding assay |
| CN1210568C (zh) * | 2002-11-18 | 2005-07-13 | 中国农业科学院原子能利用研究所 | Bt晶体蛋白CrylAc放射免疫检测试剂盒及其制备方法和检测方法 |
| GB2404022B (en) | 2004-06-14 | 2005-08-10 | Cozart Bioscience Ltd | Competitive assays for the detection of methamphetamine group drugs |
| GB2404023B (en) | 2004-07-02 | 2005-07-06 | Cozart Bioscience Ltd | Delta-9-tetrahydrocannabinol detection method |
| US20060024769A1 (en) * | 2004-07-29 | 2006-02-02 | Saladax Biomedical Inc. | Taxol immunoassay |
| US7300631B2 (en) * | 2005-05-02 | 2007-11-27 | Bioscale, Inc. | Method and apparatus for detection of analyte using a flexural plate wave device and magnetic particles |
| US7611908B2 (en) * | 2005-05-02 | 2009-11-03 | Bioscale, Inc. | Method and apparatus for therapeutic drug monitoring using an acoustic device |
| WO2006134546A2 (en) * | 2005-06-17 | 2006-12-21 | Koninklijke Philips Electronics N.V. | Accurate magnetic biosensor |
-
2007
- 2007-04-27 US US12/299,806 patent/US10488408B2/en active Active
- 2007-04-27 CN CN200780016721XA patent/CN101438163B/zh active Active
- 2007-04-27 AT AT07735694T patent/ATE514086T1/de not_active IP Right Cessation
- 2007-04-27 RU RU2008148311/15A patent/RU2444736C2/ru active
- 2007-04-27 EP EP07735694A patent/EP2027468B1/en active Active
- 2007-04-27 WO PCT/IB2007/051578 patent/WO2007132373A1/en not_active Ceased
- 2007-04-27 BR BRPI0711346A patent/BRPI0711346A8/pt not_active IP Right Cessation
- 2007-04-27 JP JP2009508593A patent/JP5200003B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP2027468B1 (en) | 2011-06-22 |
| CN101438163A (zh) | 2009-05-20 |
| BRPI0711346A8 (pt) | 2015-10-06 |
| EP2027468A1 (en) | 2009-02-25 |
| RU2008148311A (ru) | 2010-06-20 |
| JP2009536344A (ja) | 2009-10-08 |
| ATE514086T1 (de) | 2011-07-15 |
| JP5200003B2 (ja) | 2013-05-15 |
| RU2444736C2 (ru) | 2012-03-10 |
| US20090117670A1 (en) | 2009-05-07 |
| WO2007132373A1 (en) | 2007-11-22 |
| CN101438163B (zh) | 2013-05-29 |
| US10488408B2 (en) | 2019-11-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B25D | Requested change of name of applicant approved |
Owner name: KONINKLIJKE PHILIPS N.V. (NL) |
|
| B25G | Requested change of headquarter approved |
Owner name: KONINKLIJKE PHILIPS N.V. (NL) |
|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B07G | Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B07C | Technical examination (opinion): republication [chapter 7.3 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 12A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2515 DE 19-03-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |