ATE514086T1 - Nachweis von zielmolekülen in einer probe unter verwendung eines magnetfelds - Google Patents

Nachweis von zielmolekülen in einer probe unter verwendung eines magnetfelds

Info

Publication number
ATE514086T1
ATE514086T1 AT07735694T AT07735694T ATE514086T1 AT E514086 T1 ATE514086 T1 AT E514086T1 AT 07735694 T AT07735694 T AT 07735694T AT 07735694 T AT07735694 T AT 07735694T AT E514086 T1 ATE514086 T1 AT E514086T1
Authority
AT
Austria
Prior art keywords
sample
detection
magnetic field
binding molecule
target
Prior art date
Application number
AT07735694T
Other languages
English (en)
Inventor
Der Wijk Thea Van
Eduard Gerard Marie Pelssers
Jessica Amadio
Original Assignee
Koninkl Philips Electronics Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninkl Philips Electronics Nv filed Critical Koninkl Philips Electronics Nv
Application granted granted Critical
Publication of ATE514086T1 publication Critical patent/ATE514086T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/72—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables
    • G01N27/74—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids
    • G01N27/745—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids for detecting magnetic beads used in biochemical assays
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00—Magnetic particle immunoreagent carriers

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Electrochemistry (AREA)
  • Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
AT07735694T 2006-05-09 2007-04-27 Nachweis von zielmolekülen in einer probe unter verwendung eines magnetfelds ATE514086T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06113698 2006-05-09
PCT/IB2007/051578 WO2007132373A1 (en) 2006-05-09 2007-04-27 Detection of target molecules in a sample by using a magnetic field

Publications (1)

Publication Number Publication Date
ATE514086T1 true ATE514086T1 (de) 2011-07-15

Family

ID=38445621

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07735694T ATE514086T1 (de) 2006-05-09 2007-04-27 Nachweis von zielmolekülen in einer probe unter verwendung eines magnetfelds

Country Status (8)

Country Link
US (1) US10488408B2 (de)
EP (1) EP2027468B1 (de)
JP (1) JP5200003B2 (de)
CN (1) CN101438163B (de)
AT (1) ATE514086T1 (de)
BR (1) BRPI0711346A8 (de)
RU (1) RU2444736C2 (de)
WO (1) WO2007132373A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8618508B2 (en) 2008-09-25 2013-12-31 Koninklijke Philips N.V. Detection system and method
BRPI0918101A2 (pt) 2008-12-22 2015-11-24 Koninkl Philips Electronics Nv método para medir a troponina i em uma amostra, cartucho para ser utilizado em um dispositivo de ensaio e uso
JP6013912B2 (ja) * 2009-07-30 2016-10-25 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ オリゴヌクレオチドプローブのセットならびにそれに関連する方法および使用
WO2011034854A1 (en) * 2009-09-19 2011-03-24 Surgimed Biosciences, Inc. Method and apparatus for automated cell transfer therapy and hair transplantation
GB201110272D0 (en) 2011-06-17 2011-08-03 Isis Innovation Metod of detection by mass spectrometry
EP2726881A1 (de) * 2011-06-28 2014-05-07 Koninklijke Philips N.V. Vorrichtung zur untersuchung von körperflüssigkeiten
WO2013102850A1 (en) 2012-01-04 2013-07-11 Insituto De Engenharia De Sistemas E Computadores Para Os Microsistemas E As Nanotecnologias Monolithic device combining cmos with magnetoresistive sensors
CN104603611B (zh) * 2012-09-04 2019-04-05 皇家飞利浦有限公司 传感器设备和采样方法
RU2653145C2 (ru) 2012-09-04 2018-05-07 Конинклейке Филипс Н.В. Измерительное устройство и способ отбора образцов
CN105579849B (zh) * 2013-06-06 2019-02-22 微型照顾私人有限公司 在用于检测多聚靶分子的基于颗粒的测试中防止聚集的试剂、方法和设备
CA2959741A1 (en) * 2014-10-20 2016-04-28 Christopher Gordon Atwood Analyzing a sample with a construct comprising a fluorescent moiety and a magnetic moiety
US10261076B2 (en) * 2015-10-02 2019-04-16 The Board Of Trustees Of The Leland Stanford Junior University Method for detecting small molecule analytes using magnetoresistant sensors
US12339233B2 (en) * 2015-12-24 2025-06-24 Siemens Healthineers Nederland B.V. Optical detection of a substance in fluid
WO2018140719A1 (en) * 2017-01-26 2018-08-02 Confer Health, Inc. Magnetic particle-based immunoassay and methods of using the same
WO2023057823A1 (en) * 2021-10-10 2023-04-13 Alipour Elias Detecting an antigen of a virus using electrochemical analysis
EP4592678A1 (de) * 2024-01-26 2025-07-30 Technische Universität München Verfahren und vorrichtung zum nachweis einer konzentration von mindestens einem analyten in einer probe

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL82873A0 (en) 1987-06-15 1987-12-20 Orgenics Ltd Reversed competitive solid phase immunoassay for detecting single epitope analytes and kit therefor
US5445971A (en) * 1992-03-20 1995-08-29 Abbott Laboratories Magnetically assisted binding assays using magnetically labeled binding members
US5635364A (en) * 1992-03-27 1997-06-03 Abbott Laboratories Assay verification control for an automated analytical system
AU3972993A (en) 1992-04-01 1993-11-08 Regents Of The University Of California, The Non-instrumented enzyme immunoassay: general method utilizing kinetic binding effects
WO1996007101A1 (en) * 1994-08-31 1996-03-07 First Medical, Inc. Quantitative assays employing magnetizable particles for rate enhancement
US5660990A (en) * 1995-08-18 1997-08-26 Immunivest Corporation Surface immobilization of magnetically collected materials
US6586193B2 (en) 1996-04-25 2003-07-01 Genicon Sciences Corporation Analyte assay using particulate labels
JP2000510582A (ja) * 1996-04-25 2000-08-15 ゼニコン・サイエンシーズ・コーポレーション 微粒子標識を使用した分析物アッセイ
FR2758884B1 (fr) * 1997-01-30 1999-04-02 Bio Merieux Procede pour isoler, notamment detecter ou quantifier un analyte dans un milieu
US5981297A (en) * 1997-02-05 1999-11-09 The United States Of America As Represented By The Secretary Of The Navy Biosensor using magnetically-detected label
DE19822123C2 (de) * 1997-11-21 2003-02-06 Meinhard Knoll Verfahren und Vorrichtung zum Nachweis von Analyten
CA2327816A1 (en) * 1998-04-09 1999-10-21 Nycomed Imaging As Use of particulate contrast agents in diagnostic imaging for studying physiological parameters
US6287765B1 (en) * 1998-05-20 2001-09-11 Molecular Machines, Inc. Methods for detecting and identifying single molecules
CA2381732A1 (en) * 1999-08-21 2001-03-01 John S. Fox High sensitivity biomolecule detection with magnetic particles
US6897015B2 (en) * 2000-03-07 2005-05-24 Bioforce Nanosciences, Inc. Device and method of use for detection and characterization of pathogens and biological materials
RU2166751C1 (ru) 2000-03-09 2001-05-10 Никитин Петр Иванович Способ анализа смеси биологических и/или химических компонентов с использованием магнитных частиц и устройство для его осуществления
US7241630B2 (en) * 2000-04-10 2007-07-10 Randox Laboratories, Ltd. Paramagnetic particle detection
GB0124341D0 (en) 2001-10-10 2001-11-28 Randox Lab Ltd Assay
US7432105B2 (en) * 2002-08-27 2008-10-07 Kimberly-Clark Worldwide, Inc. Self-calibration system for a magnetic binding assay
CN1210568C (zh) * 2002-11-18 2005-07-13 中国农业科学院原子能利用研究所 Bt晶体蛋白CrylAc放射免疫检测试剂盒及其制备方法和检测方法
GB2404022B (en) 2004-06-14 2005-08-10 Cozart Bioscience Ltd Competitive assays for the detection of methamphetamine group drugs
GB2404023B (en) 2004-07-02 2005-07-06 Cozart Bioscience Ltd Delta-9-tetrahydrocannabinol detection method
US20060024769A1 (en) * 2004-07-29 2006-02-02 Saladax Biomedical Inc. Taxol immunoassay
US7300631B2 (en) * 2005-05-02 2007-11-27 Bioscale, Inc. Method and apparatus for detection of analyte using a flexural plate wave device and magnetic particles
US7611908B2 (en) * 2005-05-02 2009-11-03 Bioscale, Inc. Method and apparatus for therapeutic drug monitoring using an acoustic device
WO2006134546A2 (en) * 2005-06-17 2006-12-21 Koninklijke Philips Electronics N.V. Accurate magnetic biosensor

Also Published As

Publication number Publication date
EP2027468B1 (de) 2011-06-22
CN101438163A (zh) 2009-05-20
BRPI0711346A2 (pt) 2011-08-30
BRPI0711346A8 (pt) 2015-10-06
EP2027468A1 (de) 2009-02-25
RU2008148311A (ru) 2010-06-20
JP2009536344A (ja) 2009-10-08
JP5200003B2 (ja) 2013-05-15
RU2444736C2 (ru) 2012-03-10
US20090117670A1 (en) 2009-05-07
WO2007132373A1 (en) 2007-11-22
CN101438163B (zh) 2013-05-29
US10488408B2 (en) 2019-11-26

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