ATE514086T1 - Nachweis von zielmolekülen in einer probe unter verwendung eines magnetfelds - Google Patents

Nachweis von zielmolekülen in einer probe unter verwendung eines magnetfelds

Info

Publication number
ATE514086T1
ATE514086T1 AT07735694T AT07735694T ATE514086T1 AT E514086 T1 ATE514086 T1 AT E514086T1 AT 07735694 T AT07735694 T AT 07735694T AT 07735694 T AT07735694 T AT 07735694T AT E514086 T1 ATE514086 T1 AT E514086T1
Authority
AT
Austria
Prior art keywords
sample
detection
magnetic field
binding molecule
target
Prior art date
Application number
AT07735694T
Other languages
English (en)
Inventor
Der Wijk Thea Van
Eduard Gerard Marie Pelssers
Jessica Amadio
Original Assignee
Koninkl Philips Electronics Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninkl Philips Electronics Nv filed Critical Koninkl Philips Electronics Nv
Application granted granted Critical
Publication of ATE514086T1 publication Critical patent/ATE514086T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326Magnetic particles
    • G01N33/54333Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/72Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables
    • G01N27/74Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids
    • G01N27/745Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids for detecting magnetic beads used in biochemical assays
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00Magnetic particle immunoreagent carriers

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Electrochemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
AT07735694T 2006-05-09 2007-04-27 Nachweis von zielmolekülen in einer probe unter verwendung eines magnetfelds ATE514086T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06113698 2006-05-09
PCT/IB2007/051578 WO2007132373A1 (en) 2006-05-09 2007-04-27 Detection of target molecules in a sample by using a magnetic field

Publications (1)

Publication Number Publication Date
ATE514086T1 true ATE514086T1 (de) 2011-07-15

Family

ID=38445621

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07735694T ATE514086T1 (de) 2006-05-09 2007-04-27 Nachweis von zielmolekülen in einer probe unter verwendung eines magnetfelds

Country Status (8)

Country Link
US (1) US10488408B2 (de)
EP (1) EP2027468B1 (de)
JP (1) JP5200003B2 (de)
CN (1) CN101438163B (de)
AT (1) ATE514086T1 (de)
BR (1) BRPI0711346A8 (de)
RU (1) RU2444736C2 (de)
WO (1) WO2007132373A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102165305B (zh) 2008-09-25 2014-08-20 皇家飞利浦电子股份有限公司 检测系统与方法
RU2530716C2 (ru) 2008-12-22 2014-10-10 Конинклейке Филипс Электроникс Н.В. Анализ тропонина i с применением магнитных меток
DK2459743T3 (da) * 2009-07-30 2017-11-06 Hoffmann La Roche Sæt af oligonukleotidprober såvel som fremgangsmåder og anvendelser relateret dertil
WO2011034854A1 (en) * 2009-09-19 2011-03-24 Surgimed Biosciences, Inc. Method and apparatus for automated cell transfer therapy and hair transplantation
GB201110272D0 (en) 2011-06-17 2011-08-03 Isis Innovation Metod of detection by mass spectrometry
US20140127713A1 (en) * 2011-06-28 2014-05-08 Femke Karina de Theije Means for the examination of body fluids
DK2800970T3 (en) 2012-01-04 2017-01-16 Magnomics S A Monolithic device for combining CMOS with magnetoresistive sensors
US9841419B2 (en) 2012-09-04 2017-12-12 Koninklijke Philips N.V. Sensor device and a method of sampling
CN104603611B (zh) * 2012-09-04 2019-04-05 皇家飞利浦有限公司 传感器设备和采样方法
US10895571B2 (en) * 2013-06-06 2021-01-19 Siemens Healthineers Nederland B.V. Reagents, methods and devices to prevent aggregation in particle based tests for the detection of multimeric target molecules
EP3210020A1 (de) * 2014-10-20 2017-08-30 Christopher Gordon Atwood Analyse einer probe mit einem konstrukt mit einem fluoreszierenden teil und einem magnetischen teil
US10261076B2 (en) * 2015-10-02 2019-04-16 The Board Of Trustees Of The Leland Stanford Junior University Method for detecting small molecule analytes using magnetoresistant sensors
US12339233B2 (en) * 2015-12-24 2025-06-24 Siemens Healthineers Nederland B.V. Optical detection of a substance in fluid
EP3574309A4 (de) * 2017-01-26 2020-11-11 Vital Biosciences, Inc. Immuntest auf magnetpartikelbasis und verfahren zu dessen verwendung
WO2022029732A1 (en) 2020-08-07 2022-02-10 Vital Biosciences Inc. Kinetic modulation for magnetic analyte detection
WO2023057823A1 (en) * 2021-10-10 2023-04-13 Alipour Elias Detecting an antigen of a virus using electrochemical analysis
EP4592678A1 (de) * 2024-01-26 2025-07-30 Technische Universität München Verfahren und vorrichtung zum nachweis einer konzentration von mindestens einem analyten in einer probe

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL82873A0 (en) * 1987-06-15 1987-12-20 Orgenics Ltd Reversed competitive solid phase immunoassay for detecting single epitope analytes and kit therefor
US5445971A (en) * 1992-03-20 1995-08-29 Abbott Laboratories Magnetically assisted binding assays using magnetically labeled binding members
US5635364A (en) * 1992-03-27 1997-06-03 Abbott Laboratories Assay verification control for an automated analytical system
AU3972993A (en) 1992-04-01 1993-11-08 Regents Of The University Of California, The Non-instrumented enzyme immunoassay: general method utilizing kinetic binding effects
AU3493295A (en) 1994-08-31 1996-03-22 First Medical, Inc. Quantitative assays employing magnetizable particles for rate enhancement
US5660990A (en) * 1995-08-18 1997-08-26 Immunivest Corporation Surface immobilization of magnetically collected materials
IL126544A (en) * 1996-04-25 2004-08-31 Genicon Sciences Inc Analyte assay using scattered-light detectable particles
US6586193B2 (en) 1996-04-25 2003-07-01 Genicon Sciences Corporation Analyte assay using particulate labels
FR2758884B1 (fr) * 1997-01-30 1999-04-02 Bio Merieux Procede pour isoler, notamment detecter ou quantifier un analyte dans un milieu
US5981297A (en) * 1997-02-05 1999-11-09 The United States Of America As Represented By The Secretary Of The Navy Biosensor using magnetically-detected label
DE19822123C2 (de) * 1997-11-21 2003-02-06 Meinhard Knoll Verfahren und Vorrichtung zum Nachweis von Analyten
CA2327816A1 (en) * 1998-04-09 1999-10-21 Nycomed Imaging As Use of particulate contrast agents in diagnostic imaging for studying physiological parameters
US6287765B1 (en) * 1998-05-20 2001-09-11 Molecular Machines, Inc. Methods for detecting and identifying single molecules
AU6920000A (en) * 1999-08-21 2001-03-19 John S. Fox High sensitivity biomolecule detection with magnetic particles
US6897015B2 (en) * 2000-03-07 2005-05-24 Bioforce Nanosciences, Inc. Device and method of use for detection and characterization of pathogens and biological materials
RU2166751C1 (ru) * 2000-03-09 2001-05-10 Никитин Петр Иванович Способ анализа смеси биологических и/или химических компонентов с использованием магнитных частиц и устройство для его осуществления
US7241630B2 (en) * 2000-04-10 2007-07-10 Randox Laboratories, Ltd. Paramagnetic particle detection
GB0124341D0 (en) 2001-10-10 2001-11-28 Randox Lab Ltd Assay
US7432105B2 (en) * 2002-08-27 2008-10-07 Kimberly-Clark Worldwide, Inc. Self-calibration system for a magnetic binding assay
CN1210568C (zh) * 2002-11-18 2005-07-13 中国农业科学院原子能利用研究所 Bt晶体蛋白CrylAc放射免疫检测试剂盒及其制备方法和检测方法
GB2404022B (en) 2004-06-14 2005-08-10 Cozart Bioscience Ltd Competitive assays for the detection of methamphetamine group drugs
GB2404023B (en) * 2004-07-02 2005-07-06 Cozart Bioscience Ltd Delta-9-tetrahydrocannabinol detection method
US20060024769A1 (en) * 2004-07-29 2006-02-02 Saladax Biomedical Inc. Taxol immunoassay
US7611908B2 (en) * 2005-05-02 2009-11-03 Bioscale, Inc. Method and apparatus for therapeutic drug monitoring using an acoustic device
US7300631B2 (en) * 2005-05-02 2007-11-27 Bioscale, Inc. Method and apparatus for detection of analyte using a flexural plate wave device and magnetic particles
CN101198870A (zh) * 2005-06-17 2008-06-11 皇家飞利浦电子股份有限公司 精密磁性生物传感器

Also Published As

Publication number Publication date
JP5200003B2 (ja) 2013-05-15
WO2007132373A1 (en) 2007-11-22
CN101438163A (zh) 2009-05-20
RU2444736C2 (ru) 2012-03-10
BRPI0711346A2 (pt) 2011-08-30
CN101438163B (zh) 2013-05-29
JP2009536344A (ja) 2009-10-08
RU2008148311A (ru) 2010-06-20
BRPI0711346A8 (pt) 2015-10-06
US10488408B2 (en) 2019-11-26
US20090117670A1 (en) 2009-05-07
EP2027468A1 (de) 2009-02-25
EP2027468B1 (de) 2011-06-22

Similar Documents

Publication Publication Date Title
BRPI0711346A8 (pt) Método para detectar um alvo em uma amostra suspeita de conter o alvo, e, uso de um magneto
WO2009117033A3 (en) Scanning analyzer for single molecule detection and methods of use
WO2011109372A8 (en) Ultra-sensitive detection of molecules using dual detection methods
DE602005013225D1 (de) Aptamer-nanopartikelkonjugate und verwendungsverfahren zur detektion von zielanalyten
WO2011109364A3 (en) Ultra-sensitive detection of molecules or particles using beads or other capture objects
ATE538386T1 (de) Nachweis von krebs anhand von erhöhten bcl-2- konzentrationen
ATE556030T1 (de) Ultrasensitiver nachweis von analyten
WO2008035073A3 (en) Method of detecting interactions on a microarray using nuclear magnetic resonance
DE602007004666D1 (de) Verfahren zum analytennachweis unter verwendung von proximitätssonden
ATE524742T1 (de) Sequenzielle analyse biologischer proben mit zwischenbleichung eines fluoreszenzdetektors
TW200801203A (en) Multiplexed analyses of test samples
BRPI0510680A (pt) dispositivo e método para detectar qualitativamente e/ou quantitativamente interações moleculares entre moléculas de sonda e moléculas alvo, e, uso de um dispositivo
WO2005089524A3 (en) Compositions and methods for detection of single molecules
NZ629703A (en) Methods and compositions for detecting multiple analytes with a single signal
SE0800871L (sv) Analysförfarande och anordning
MX2010004335A (es) Metodo y sistema para la deteccion de un tipo seleccionado de moleculas en una muestra.
ATE466108T1 (de) Optoelektronisches detektionssystem
WO2007005666A3 (en) System and method of analyte detection using differential receptors
WO2008152528A3 (en) Method for the diagnosis or the screening of an arbovirus infection, reagents useful in said method and their applications
WO2009134327A3 (en) Methods and reagents to increase the sensitivity of enzyme metallographic detection
ATE529533T1 (de) Verfahren zum nachweis von analyten in einer probe
JP2016520846A5 (de)
BRPI1013201A2 (pt) meios e métodos para reconhecer o desenvolvimento de doenças cardiovascular em um indivíduo
WO2007147141A3 (en) Methods for detecting molecular complexes
WO2007067680A3 (en) Particle-based analyte characterization

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties