BRPI0712066A2 - meio de contraste para ressonáncia magnética usando polietilenoglicol e método para captação de imagens de ressonáncia magnética - Google Patents

meio de contraste para ressonáncia magnética usando polietilenoglicol e método para captação de imagens de ressonáncia magnética Download PDF

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Publication number
BRPI0712066A2
BRPI0712066A2 BRPI0712066-4A BRPI0712066A BRPI0712066A2 BR PI0712066 A2 BRPI0712066 A2 BR PI0712066A2 BR PI0712066 A BRPI0712066 A BR PI0712066A BR PI0712066 A2 BRPI0712066 A2 BR PI0712066A2
Authority
BR
Brazil
Prior art keywords
magnetic resonance
polyethylene glycol
contrast agent
compound
labeled
Prior art date
Application number
BRPI0712066-4A
Other languages
English (en)
Portuguese (pt)
Inventor
Suzuki Yoshikazu
Miura Iwao
Iida Mitsuro
Original Assignee
Otsuka Pharmaceutical Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co., Ltd. filed Critical Otsuka Pharmaceutical Co., Ltd.
Publication of BRPI0712066A2 publication Critical patent/BRPI0712066A2/pt

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • G01R33/281—Means for the use of in vitro contrast agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
    • A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/12—Macromolecular compounds
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N24/00—Investigating or analyzing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects
    • G01N24/08—Investigating or analyzing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects by using nuclear magnetic resonance
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/46—NMR spectroscopy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/483—NMR imaging systems with selection of signals or spectra from particular regions of the volume, e.g. in vivo spectroscopy
    • G01R33/485—NMR imaging systems with selection of signals or spectra from particular regions of the volume, e.g. in vivo spectroscopy based on chemical shift information [CSI] or spectroscopic imaging, e.g. to acquire the spatial distributions of metabolites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/5601—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution involving use of a contrast agent for contrast manipulation, e.g. a paramagnetic, super-paramagnetic, ferromagnetic or hyperpolarised contrast agent

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Optics & Photonics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Epidemiology (AREA)
  • Signal Processing (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
BRPI0712066-4A 2006-05-17 2007-05-14 meio de contraste para ressonáncia magnética usando polietilenoglicol e método para captação de imagens de ressonáncia magnética BRPI0712066A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2006-138236 2006-05-17
JP2006138236 2006-05-17
PCT/JP2007/059849 WO2007132806A1 (ja) 2006-05-17 2007-05-14 ポリエチレングリコールを利用した磁気共鳴造影剤及び磁気共鳴撮像方法

Publications (1)

Publication Number Publication Date
BRPI0712066A2 true BRPI0712066A2 (pt) 2011-12-20

Family

ID=38693897

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0712066-4A BRPI0712066A2 (pt) 2006-05-17 2007-05-14 meio de contraste para ressonáncia magnética usando polietilenoglicol e método para captação de imagens de ressonáncia magnética

Country Status (11)

Country Link
US (1) US20090162291A1 (de)
EP (1) EP2020244B1 (de)
JP (1) JP5435940B2 (de)
KR (1) KR101463634B1 (de)
CN (2) CN104324393A (de)
AU (1) AU2007250851A1 (de)
BR (1) BRPI0712066A2 (de)
CA (1) CA2652264C (de)
ES (1) ES2454968T3 (de)
TW (2) TWI400091B (de)
WO (1) WO2007132806A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104324393A (zh) * 2006-05-17 2015-02-04 大塚制药株式会社 利用聚乙二醇的磁共振造影剂及磁共振成像方法
JP6234064B2 (ja) * 2012-05-23 2017-11-22 キヤノン株式会社 重合体、前記重合体を用いた核磁気共鳴分析用または磁気共鳴イメージング用の造影剤、化合物、前記重合体を用いた核磁気共鳴分析方法および磁気共鳴イメージング方法
DE102019220504A1 (de) * 2019-12-23 2021-06-24 Robert Bosch Gesellschaft mit beschränkter Haftung Magnetresonanzvorrichtung

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5368840A (en) * 1990-04-10 1994-11-29 Imarx Pharmaceutical Corp. Natural polymers as contrast media for magnetic resonance imaging
DE69131721T2 (de) * 1990-04-10 2000-03-02 Imarx Pharmaceutical Corp., Tucson Polymere als Kontrastmittel bei magnetischer Resonanz
US5650234A (en) 1994-09-09 1997-07-22 Surface Engineering Technologies, Division Of Innerdyne, Inc. Electrophilic polyethylene oxides for the modification of polysaccharides, polypeptides (proteins) and surfaces
US6210655B1 (en) * 1997-06-18 2001-04-03 University Of Medicine & Dentistry Of Nj Site-specific 13C-enriched reagents for diagnostic medicine by magnetic resonance imaging
WO1998057578A1 (en) 1997-06-18 1998-12-23 University Of Medicine & Dentistry Of New Jersey Application of ?13c-13c, 13c-15n, and 13c-13c-15¿n isotopically enriched proteins as tissue-directed image-enhancement reagents for magnetic resonance imaging
CN104324393A (zh) * 2006-05-17 2015-02-04 大塚制药株式会社 利用聚乙二醇的磁共振造影剂及磁共振成像方法

Also Published As

Publication number Publication date
CA2652264C (en) 2015-01-13
KR101463634B1 (ko) 2014-11-19
EP2020244B1 (de) 2014-03-05
KR20090019842A (ko) 2009-02-25
TWI400091B (zh) 2013-07-01
WO2007132806A1 (ja) 2007-11-22
CN104324393A (zh) 2015-02-04
JPWO2007132806A1 (ja) 2009-09-24
CN101448529A (zh) 2009-06-03
JP5435940B2 (ja) 2014-03-05
EP2020244A4 (de) 2012-12-26
AU2007250851A1 (en) 2007-11-22
ES2454968T3 (es) 2014-04-14
EP2020244A1 (de) 2009-02-04
TW201336515A (zh) 2013-09-16
CA2652264A1 (en) 2007-11-22
TW200812624A (en) 2008-03-16
US20090162291A1 (en) 2009-06-25
TWI501780B (zh) 2015-10-01

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06H Technical and formal requirements: requirement cancelled [chapter 6.8 patent gazette]

Free format text: REF. A RPI NO 2154 DE 17/04/2012. ANULACAO DA EXIGENCIA 6.6 POR TER SIDO INDEVIDA. REQUERENTE NAO APRESENTOU RESPOSTA A EXIGENCIA CONFORME DISPOE A RESOLUCAO 207 DE 24/04/2009, ENTRETANTO, A RESPOSTA CONSTA NO FORMULARIO DE DEPOSITO.

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07G Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 12A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2514 DE 12-03-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.