BRPI0713380A2 - Métodos para determinar in vitro a quantidade de ácidos nucleicos nucleares em pelo menos uma célula, e para diagnosticar e/ou prognosticar câncer em um indivíduo humano ou animal - Google Patents

Métodos para determinar in vitro a quantidade de ácidos nucleicos nucleares em pelo menos uma célula, e para diagnosticar e/ou prognosticar câncer em um indivíduo humano ou animal Download PDF

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Publication number
BRPI0713380A2
BRPI0713380A2 BRPI0713380-4A BRPI0713380A BRPI0713380A2 BR PI0713380 A2 BRPI0713380 A2 BR PI0713380A2 BR PI0713380 A BRPI0713380 A BR PI0713380A BR PI0713380 A2 BRPI0713380 A2 BR PI0713380A2
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Brazil
Prior art keywords
vitro
human
diagnosing
determining
cell
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BRPI0713380-4A
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English (en)
Inventor
Hendrikus Wilhelmus Hendriks Bernardus
Robert Vossenaar Erik
Spekowius Gerhard
Cornelis Van Der Vaart Nijs
Kuiper Stein
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Koninklijke Philips Electonics N. V.
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Publication of BRPI0713380A2 publication Critical patent/BRPI0713380A2/pt

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    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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    • G01N33/582Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • CCHEMISTRY; METALLURGY
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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    • GPHYSICS
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
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    • G01N33/502Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5035Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on sub-cellular localization
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    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5076Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving cell organelles, e.g. Golgi complex, endoplasmic reticulum
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    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/0002Inspection of images, e.g. flaw detection
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    • G06T7/00Image analysis
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    • G06COMPUTING OR CALCULATING; COUNTING
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    • G06T2207/10Image acquisition modality
    • G06T2207/10056Microscopic image
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/30Subject of image; Context of image processing
    • G06T2207/30004Biomedical image processing
    • G06T2207/30024Cell structures in vitro; Tissue sections in vitro

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Abstract

MéTODOS PARA DETERMINAR IN VITRO A QUANTIDADE DE áCIDOS NUCLEICOS NUCLEARES EM PELO MENOS UMA CéLULA, E PARA DIAGNOSTICAR E/OU PROGNOSTICAR CáNCER EM UM INDIVìDUO HUMANO OU ANIMAL. A invenção refere-se a um método para determinar in vitro a quantidade de DNA nuclear dentro de uma célula humana ou animal, empregando-se medição de absorção UV com luz UV. A invenção também refere-se a um método para detectar in vitro células cancerosas em uma amostra biológica com base nos princípios acima mencionados. A invenção também se refere a um método in vitro de diagnosticar ou prognosticar a ocorrência provável de câncer em um indivíduo humano ou animal.
BRPI0713380-4A 2006-06-29 2007-05-14 Métodos para determinar in vitro a quantidade de ácidos nucleicos nucleares em pelo menos uma célula, e para diagnosticar e/ou prognosticar câncer em um indivíduo humano ou animal BRPI0713380A2 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP06116336 2006-06-29
EP06116336.6 2006-06-29
EP06118438.8 2006-08-04
EP06118438 2006-08-04
PCT/IB2007/051810 WO2008001235A2 (en) 2006-06-29 2007-05-14 An in vitro method of detecting and/or diagnosing cancer using uv light based dna image cytometry

Publications (1)

Publication Number Publication Date
BRPI0713380A2 true BRPI0713380A2 (pt) 2012-03-20

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BRPI0713380-4A BRPI0713380A2 (pt) 2006-06-29 2007-05-14 Métodos para determinar in vitro a quantidade de ácidos nucleicos nucleares em pelo menos uma célula, e para diagnosticar e/ou prognosticar câncer em um indivíduo humano ou animal

Country Status (7)

Country Link
US (1) US9057729B2 (pt)
EP (1) EP2038651B1 (pt)
JP (1) JP2009542200A (pt)
CN (1) CN104849228B (pt)
BR (1) BRPI0713380A2 (pt)
RU (1) RU2009102834A (pt)
WO (1) WO2008001235A2 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102017107348B4 (de) 2017-04-05 2019-03-14 Olympus Soft Imaging Solutions Gmbh Verfahren zur zytometrischen Analyse von Zellproben
BR112022007712A2 (pt) 2019-10-22 2022-07-12 S D Sight Diagnostics Ltd Contabilização de erros em medições ópticas
AU2020402284B2 (en) * 2019-12-12 2026-02-26 S.D. Sight Diagnostics Ltd Off-focus microscopic images of a sample
MX2022007119A (es) 2019-12-12 2022-07-11 S D Sight Diagnostics Ltd Deteccion de plaquetas en una muestra de sangre.
US11551360B2 (en) 2020-04-28 2023-01-10 QATAR UNIVERSITY, Office of Academic Research Device and method for cancer detection

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US3675768A (en) * 1969-03-17 1972-07-11 Gildardo Legorreta Sanchez Method and apparatus for classifying and segregating particles with electrical and optical means
US3699336A (en) * 1969-08-15 1972-10-17 Hycel Inc Biological cell analyzing system
US4767717A (en) * 1985-05-02 1988-08-30 Baisden C Robert Method of detecting and quantitating cell malignancy in biological tissue
SU1451598A1 (ru) 1986-05-29 1989-01-15 Северо-Кавказский научно-исследовательский институт фитопатологии Способ определени целостности дер в срезах биологической ткани на цитологическом препарате
US5932872A (en) * 1994-07-01 1999-08-03 Jeffrey H. Price Autofocus system for scanning microscopy having a volume image formation
US5871902A (en) * 1994-12-09 1999-02-16 The Gene Pool, Inc. Sequence-specific detection of nucleic acid hybrids using a DNA-binding molecule or assembly capable of discriminating perfect hybrids from non-perfect hybrids
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AU5209199A (en) * 1998-07-08 2000-02-01 Regents Of The University Of California, The Use of fluorescent reagents in identification of cancerous cells and activated lymphocytes
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JP2005502872A (ja) * 2001-09-07 2005-01-27 バースタイン テクノロジーズ,インコーポレイティド 光バイオディスクシステムを使用した、核の形態に基づく白血球の型の識別および定量
US20040197839A1 (en) * 2003-04-04 2004-10-07 Bioview Ltd. Methods of detecting cancer cells in biological samples
JP4815349B2 (ja) * 2004-06-24 2011-11-16 オリンパス株式会社 蛍光相関分光装置

Also Published As

Publication number Publication date
EP2038651B1 (en) 2017-03-29
US20090197272A1 (en) 2009-08-06
CN104849228A (zh) 2015-08-19
RU2009102834A (ru) 2010-08-10
WO2008001235A2 (en) 2008-01-03
WO2008001235A3 (en) 2008-02-21
US9057729B2 (en) 2015-06-16
EP2038651A2 (en) 2009-03-25
JP2009542200A (ja) 2009-12-03
CN104849228B (zh) 2018-04-13

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B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

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