BRPI0713380A2 - Métodos para determinar in vitro a quantidade de ácidos nucleicos nucleares em pelo menos uma célula, e para diagnosticar e/ou prognosticar câncer em um indivíduo humano ou animal - Google Patents
Métodos para determinar in vitro a quantidade de ácidos nucleicos nucleares em pelo menos uma célula, e para diagnosticar e/ou prognosticar câncer em um indivíduo humano ou animal Download PDFInfo
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- BRPI0713380A2 BRPI0713380A2 BRPI0713380-4A BRPI0713380A BRPI0713380A2 BR PI0713380 A2 BRPI0713380 A2 BR PI0713380A2 BR PI0713380 A BRPI0713380 A BR PI0713380A BR PI0713380 A2 BRPI0713380 A2 BR PI0713380A2
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1468—Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle
- G01N15/147—Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle the analysis being performed on a sample stream
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
- G01N21/33—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using ultraviolet light
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5035—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on sub-cellular localization
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5076—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving cell organelles, e.g. Golgi complex, endoplasmic reticulum
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
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- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T7/00—Image analysis
- G06T7/0002—Inspection of images, e.g. flaw detection
- G06T7/0012—Biomedical image inspection
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- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T7/00—Image analysis
- G06T7/40—Analysis of texture
- G06T7/41—Analysis of texture based on statistical description of texture
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- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
- G06V20/00—Scenes; Scene-specific elements
- G06V20/60—Type of objects
- G06V20/69—Microscopic objects, e.g. biological cells or cellular parts
- G06V20/693—Acquisition
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- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T2207/00—Indexing scheme for image analysis or image enhancement
- G06T2207/10—Image acquisition modality
- G06T2207/10056—Microscopic image
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- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T2207/00—Indexing scheme for image analysis or image enhancement
- G06T2207/30—Subject of image; Context of image processing
- G06T2207/30004—Biomedical image processing
- G06T2207/30024—Cell structures in vitro; Tissue sections in vitro
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- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
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- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
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- General Physics & Mathematics (AREA)
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- Toxicology (AREA)
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Abstract
MéTODOS PARA DETERMINAR IN VITRO A QUANTIDADE DE áCIDOS NUCLEICOS NUCLEARES EM PELO MENOS UMA CéLULA, E PARA DIAGNOSTICAR E/OU PROGNOSTICAR CáNCER EM UM INDIVìDUO HUMANO OU ANIMAL. A invenção refere-se a um método para determinar in vitro a quantidade de DNA nuclear dentro de uma célula humana ou animal, empregando-se medição de absorção UV com luz UV. A invenção também refere-se a um método para detectar in vitro células cancerosas em uma amostra biológica com base nos princípios acima mencionados. A invenção também se refere a um método in vitro de diagnosticar ou prognosticar a ocorrência provável de câncer em um indivíduo humano ou animal.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06116336 | 2006-06-29 | ||
| EP06116336.6 | 2006-06-29 | ||
| EP06118438.8 | 2006-08-04 | ||
| EP06118438 | 2006-08-04 | ||
| PCT/IB2007/051810 WO2008001235A2 (en) | 2006-06-29 | 2007-05-14 | An in vitro method of detecting and/or diagnosing cancer using uv light based dna image cytometry |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0713380A2 true BRPI0713380A2 (pt) | 2012-03-20 |
Family
ID=38617949
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0713380-4A BRPI0713380A2 (pt) | 2006-06-29 | 2007-05-14 | Métodos para determinar in vitro a quantidade de ácidos nucleicos nucleares em pelo menos uma célula, e para diagnosticar e/ou prognosticar câncer em um indivíduo humano ou animal |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9057729B2 (pt) |
| EP (1) | EP2038651B1 (pt) |
| JP (1) | JP2009542200A (pt) |
| CN (1) | CN104849228B (pt) |
| BR (1) | BRPI0713380A2 (pt) |
| RU (1) | RU2009102834A (pt) |
| WO (1) | WO2008001235A2 (pt) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102017107348B4 (de) | 2017-04-05 | 2019-03-14 | Olympus Soft Imaging Solutions Gmbh | Verfahren zur zytometrischen Analyse von Zellproben |
| BR112022007712A2 (pt) | 2019-10-22 | 2022-07-12 | S D Sight Diagnostics Ltd | Contabilização de erros em medições ópticas |
| AU2020402284B2 (en) * | 2019-12-12 | 2026-02-26 | S.D. Sight Diagnostics Ltd | Off-focus microscopic images of a sample |
| MX2022007119A (es) | 2019-12-12 | 2022-07-11 | S D Sight Diagnostics Ltd | Deteccion de plaquetas en una muestra de sangre. |
| US11551360B2 (en) | 2020-04-28 | 2023-01-10 | QATAR UNIVERSITY, Office of Academic Research | Device and method for cancer detection |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3327119A (en) * | 1964-03-26 | 1967-06-20 | Ibm | Method and apparatus for detecting cancer cells |
| US3675768A (en) * | 1969-03-17 | 1972-07-11 | Gildardo Legorreta Sanchez | Method and apparatus for classifying and segregating particles with electrical and optical means |
| US3699336A (en) * | 1969-08-15 | 1972-10-17 | Hycel Inc | Biological cell analyzing system |
| US4767717A (en) * | 1985-05-02 | 1988-08-30 | Baisden C Robert | Method of detecting and quantitating cell malignancy in biological tissue |
| SU1451598A1 (ru) | 1986-05-29 | 1989-01-15 | Северо-Кавказский научно-исследовательский институт фитопатологии | Способ определени целостности дер в срезах биологической ткани на цитологическом препарате |
| US5932872A (en) * | 1994-07-01 | 1999-08-03 | Jeffrey H. Price | Autofocus system for scanning microscopy having a volume image formation |
| US5871902A (en) * | 1994-12-09 | 1999-02-16 | The Gene Pool, Inc. | Sequence-specific detection of nucleic acid hybrids using a DNA-binding molecule or assembly capable of discriminating perfect hybrids from non-perfect hybrids |
| US6165734A (en) * | 1995-12-12 | 2000-12-26 | Applied Spectral Imaging Ltd. | In-situ method of analyzing cells |
| AU5209199A (en) * | 1998-07-08 | 2000-02-01 | Regents Of The University Of California, The | Use of fluorescent reagents in identification of cancerous cells and activated lymphocytes |
| US7218764B2 (en) * | 2000-12-04 | 2007-05-15 | Cytokinetics, Inc. | Ploidy classification method |
| US6944322B2 (en) * | 2001-03-28 | 2005-09-13 | Visiongate, Inc. | Optical tomography of small objects using parallel ray illumination and post-specimen optical magnification |
| JP2005502872A (ja) * | 2001-09-07 | 2005-01-27 | バースタイン テクノロジーズ,インコーポレイティド | 光バイオディスクシステムを使用した、核の形態に基づく白血球の型の識別および定量 |
| US20040197839A1 (en) * | 2003-04-04 | 2004-10-07 | Bioview Ltd. | Methods of detecting cancer cells in biological samples |
| JP4815349B2 (ja) * | 2004-06-24 | 2011-11-16 | オリンパス株式会社 | 蛍光相関分光装置 |
-
2007
- 2007-05-14 CN CN201510127627.8A patent/CN104849228B/zh not_active Expired - Fee Related
- 2007-05-14 EP EP07735881.0A patent/EP2038651B1/en not_active Not-in-force
- 2007-05-14 BR BRPI0713380-4A patent/BRPI0713380A2/pt not_active IP Right Cessation
- 2007-05-14 JP JP2009517492A patent/JP2009542200A/ja active Pending
- 2007-05-14 RU RU2009102834/15A patent/RU2009102834A/ru not_active Application Discontinuation
- 2007-05-14 WO PCT/IB2007/051810 patent/WO2008001235A2/en not_active Ceased
- 2007-05-14 US US12/305,399 patent/US9057729B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP2038651B1 (en) | 2017-03-29 |
| US20090197272A1 (en) | 2009-08-06 |
| CN104849228A (zh) | 2015-08-19 |
| RU2009102834A (ru) | 2010-08-10 |
| WO2008001235A2 (en) | 2008-01-03 |
| WO2008001235A3 (en) | 2008-02-21 |
| US9057729B2 (en) | 2015-06-16 |
| EP2038651A2 (en) | 2009-03-25 |
| JP2009542200A (ja) | 2009-12-03 |
| CN104849228B (zh) | 2018-04-13 |
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Legal Events
| Date | Code | Title | Description |
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| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 4A E 5A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: NAO APRESENTADA A GUIA DE CUMPRIMENTO DE EXIGENCIA. REFERENTE AS 4A E 5A ANUIDADES. |