BRPI0715584B8 - método para produzir um l-aminoácido - Google Patents

método para produzir um l-aminoácido

Info

Publication number
BRPI0715584B8
BRPI0715584B8 BRPI0715584A BRPI0715584A BRPI0715584B8 BR PI0715584 B8 BRPI0715584 B8 BR PI0715584B8 BR PI0715584 A BRPI0715584 A BR PI0715584A BR PI0715584 A BRPI0715584 A BR PI0715584A BR PI0715584 B8 BRPI0715584 B8 BR PI0715584B8
Authority
BR
Brazil
Prior art keywords
amino acid
produce
bacterium
producing
alcohol dehydrogenase
Prior art date
Application number
BRPI0715584A
Other languages
English (en)
Inventor
Borisovna Altman Irina
Matsui Kazuhiko
Romanovich Ptitsyn Leonid
Terashita Masaru
Nikolaevna Mokhova Olga
Abramovna Yampolskaya Tatyana
Aleksandrovna Kotliarova Veronika
Usuda Yoshihiro
Ivanovich Kozlov Yury
Original Assignee
Ajinomoto Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from RU2006125964/13A external-priority patent/RU2006125964A/ru
Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk
Publication of BRPI0715584A2 publication Critical patent/BRPI0715584A2/pt
Publication of BRPI0715584B1 publication Critical patent/BRPI0715584B1/pt
Publication of BRPI0715584B8 publication Critical patent/BRPI0715584B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/10—Citrulline; Arginine; Ornithine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/14—Glutamic acid; Glutamine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
    • C12P13/222—Phenylalanine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
    • C12P13/227—Tryptophan
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/24—Proline; Hydroxyproline; Histidine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01002—Alcohol dehydrogenase (NADP+) (1.1.1.2), i.e. aldehyde reductase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

metodo para produzir um l-aminoácido. método para produzir um l-aminoácido é descrito, por exemplo, l-treonina, l-lisina, l-histidina, l-fenilalanina, l-arginina, l-triptofano, ou ácido l-glutâmico, usando uma bactéria da família enterobaci'eriaceae, em que a bactéria tenha sido modificada para acentuar uma atividade de um álcool desidrogenase selvagem codificada pelo gene adhe ou uma álcool desidrogenase mutante que é resistente a inativação aeróbica.
BRPI0715584A 2006-07-19 2007-07-12 método para produzir um l-aminoácido BRPI0715584B8 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
RU2006125964 2006-07-19
RU2006125964/13A RU2006125964A (ru) 2006-07-19 2006-07-19 Способ получения l-аминокислот с использованием бактерии семейства enterobacteriaceae
US88567107P 2007-01-19 2007-01-19
US60885671 2007-01-19
PCT/JP2007/064304 WO2008010565A2 (en) 2006-07-19 2007-07-12 A method for producing an l-amino acid using a bacterium of the enterobacteriaceae family

Publications (3)

Publication Number Publication Date
BRPI0715584A2 BRPI0715584A2 (pt) 2013-03-12
BRPI0715584B1 BRPI0715584B1 (pt) 2017-01-31
BRPI0715584B8 true BRPI0715584B8 (pt) 2017-02-21

Family

ID=38957208

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0715584A BRPI0715584B8 (pt) 2006-07-19 2007-07-12 método para produzir um l-aminoácido

Country Status (6)

Country Link
US (2) US20090203090A1 (pt)
EP (1) EP2046949B1 (pt)
JP (1) JP5407858B2 (pt)
CN (2) CN103215319A (pt)
BR (1) BRPI0715584B8 (pt)
WO (1) WO2008010565A2 (pt)

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RU2004124226A (ru) 2004-08-10 2006-01-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) Использование фосфокетолазы для продукции полезных метаболитов
US7915018B2 (en) * 2004-10-22 2011-03-29 Ajinomoto Co., Inc. Method for producing L-amino acids using bacteria of the Enterobacteriaceae family
EP2004803A2 (en) 2006-03-23 2008-12-24 Ajinomoto Co., Inc. A method for producing an l-amino acid using bacterium of theenterobacteriaceae family with attenuated expression of a gene coding for small rna
WO2008044614A1 (en) 2006-09-28 2008-04-17 Ajinomoto Co., Inc. Method for producing 4-hydroxy-l-isoleucine
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WO2008133131A1 (ja) * 2007-04-16 2008-11-06 Ajinomoto Co., Inc. 有機酸の製造方法
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RU2395579C2 (ru) 2007-12-21 2010-07-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТЫ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ, ПРИНАДЛЕЖАЩЕЙ К РОДУ Escherichia
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JP2012100537A (ja) * 2009-03-06 2012-05-31 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
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CN103642765B (zh) * 2013-12-25 2015-11-18 南京工业大学 醇脱氢酶突变体及其应用
CN104004742A (zh) * 2014-04-08 2014-08-27 北京贝奥康泰医药科技有限公司 用于培养微生物表达肝素酶iii的培养基
JP2017131111A (ja) 2014-06-03 2017-08-03 味の素株式会社 Ｌ−アミノ酸の製造法
DK3250700T3 (da) * 2015-01-27 2020-07-27 Cysbio Aps Fremgangsmåde til fremstilling af L-serin under anvendelse af genmodificerede mikroorganismer, der mangler serin-nedbrydningspathways
WO2017139362A1 (en) 2016-02-08 2017-08-17 Cargill, Incorporated Protein concentrates from oil seeds and methods of producing the same
CN109666617B (zh) * 2017-10-13 2021-02-02 四川利尔生物科技有限公司 一种l-高丝氨酸的生产菌株及其构建方法和应用
CN110004081B (zh) * 2019-03-25 2022-09-13 江西省科学院微生物研究所 一种能拆分(+/-)γ-内酰胺得到(+)γ-内酰胺的菠萝泛菌及其应用
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Also Published As

Publication number Publication date
CN101490251B (zh) 2016-06-29
EP2046949A2 (en) 2009-04-15
CN101490251A (zh) 2009-07-22
JP2009543543A (ja) 2009-12-10
BRPI0715584A2 (pt) 2013-03-12
JP5407858B2 (ja) 2014-02-05
WO2008010565A3 (en) 2008-05-29
US20150203881A1 (en) 2015-07-23
EP2046949B1 (en) 2014-01-15
CN103215319A (zh) 2013-07-24
US20090203090A1 (en) 2009-08-13
BRPI0715584B1 (pt) 2017-01-31
WO2008010565A2 (en) 2008-01-24

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