DK3250700T3 - Fremgangsmåde til fremstilling af L-serin under anvendelse af genmodificerede mikroorganismer, der mangler serin-nedbrydningspathways - Google Patents

Fremgangsmåde til fremstilling af L-serin under anvendelse af genmodificerede mikroorganismer, der mangler serin-nedbrydningspathways Download PDF

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DK3250700T3
DK3250700T3 DK16701661.7T DK16701661T DK3250700T3 DK 3250700 T3 DK3250700 T3 DK 3250700T3 DK 16701661 T DK16701661 T DK 16701661T DK 3250700 T3 DK3250700 T3 DK 3250700T3
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serine
production
genetically modified
modified microorganisms
degradation pathways
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DK16701661.7T
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Hemanshu Mundhada
Alex Toftgaard Nielsen
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Cysbio Aps
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DK16701661.7T 2015-01-27 2016-01-27 Fremgangsmåde til fremstilling af L-serin under anvendelse af genmodificerede mikroorganismer, der mangler serin-nedbrydningspathways DK3250700T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15152643 2015-01-27
PCT/EP2016/051701 WO2016120326A1 (en) 2015-01-27 2016-01-27 Method for the production of l-serine using genetically engineered microorganisms deficient in serine degradation pathways

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DK3250700T3 true DK3250700T3 (da) 2020-07-27

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DK16701661.7T DK3250700T3 (da) 2015-01-27 2016-01-27 Fremgangsmåde til fremstilling af L-serin under anvendelse af genmodificerede mikroorganismer, der mangler serin-nedbrydningspathways
DK16701783.9T DK3250701T3 (da) 2015-01-27 2016-01-27 Genmodificerede mikroorganismer med forbedret tolerance over for L-serin

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US (3) US10793826B2 (da)
EP (3) EP3250701B8 (da)
JP (2) JP6720194B2 (da)
CN (2) CN107406864B (da)
CA (2) CA2975010A1 (da)
DK (2) DK3250700T3 (da)
ES (2) ES2847673T3 (da)
HU (1) HUE050530T2 (da)
LT (1) LT3250701T (da)
MY (2) MY186949A (da)
PL (1) PL3250700T3 (da)
SI (1) SI3250701T1 (da)
WO (2) WO2016120345A1 (da)

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Publication number Priority date Publication date Assignee Title
DK3250700T3 (da) * 2015-01-27 2020-07-27 Cysbio Aps Fremgangsmåde til fremstilling af L-serin under anvendelse af genmodificerede mikroorganismer, der mangler serin-nedbrydningspathways
US10858676B2 (en) * 2017-05-22 2020-12-08 Ajinomoto Co., Inc. Method for producing objective substance
CN110229853B (zh) * 2019-07-02 2021-06-01 武汉轻工大学 一种l-丝氨酸的制备方法
CN111019877B (zh) * 2019-12-31 2022-04-19 浙江工业大学 一种产l-半胱氨酸的基因工程菌、构建方法及应用
EP3960879A1 (en) * 2020-09-01 2022-03-02 Metabolic Explorer Microorganism and method for the improved production of alanine
WO2024013258A1 (en) 2022-07-15 2024-01-18 Cysbio Aps Production of cysteine or cystine from serine in fermentation medium
WO2024028428A1 (en) 2022-08-04 2024-02-08 Metabolic Explorer Microorganism and method for the improved production of serine and/or cysteine
AU2023362566A1 (en) 2022-10-20 2025-04-24 Cysbio Aps Genetically modified host cells producing l-serine
AU2023423758A1 (en) 2023-01-09 2025-08-21 Evonik Operations Gmbh Fermentative production guanidinoacetic acid (gaa) from serine by attenuating l serine ammonia lyase activity in microorganisms
CN120476204A (zh) 2023-01-09 2025-08-12 赢创运营有限公司 通过使用具有增强的l-丝氨酸羟甲基转移酶活性的微生物来从丝氨酸发酵产生胍基乙酸（gaa）
WO2024224355A1 (en) 2023-04-26 2024-10-31 Cysbio Aps A low dose formulation of l-serine for liver health and fatty liver diseases
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