BRPI0717335A2 - Anticorpos anti-htnfalfa cristalinos - Google Patents

Anticorpos anti-htnfalfa cristalinos

Info

Publication number
BRPI0717335A2
BRPI0717335A2 BRPI0717335-0A2A BRPI0717335A BRPI0717335A2 BR PI0717335 A2 BRPI0717335 A2 BR PI0717335A2 BR PI0717335 A BRPI0717335 A BR PI0717335A BR PI0717335 A2 BRPI0717335 A2 BR PI0717335A2
Authority
BR
Brazil
Prior art keywords
htnfalfa
crystaline
antibodies
crystals
antibody
Prior art date
Application number
BRPI0717335-0A2A
Other languages
English (en)
Inventor
David W Borhani
Wolfgang Fraunhofer
Hans-Juergen Krause
Anette Koenigsdorfer
Gerhard Winter
Stefan Gottschalk
Original Assignee
Abbott Biotech Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39364990&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0717335(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbott Biotech Ltd filed Critical Abbott Biotech Ltd
Publication of BRPI0717335A2 publication Critical patent/BRPI0717335A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
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    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
    • C07K2299/00—Coordinates from 3D structures of peptides, e.g. proteins or enzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Communicable Diseases (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Obesity (AREA)
  • Virology (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
BRPI0717335-0A2A 2006-10-27 2007-10-25 Anticorpos anti-htnfalfa cristalinos BRPI0717335A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US85510406P 2006-10-27 2006-10-27
PCT/US2007/022622 WO2008057240A2 (en) 2006-10-27 2007-10-25 Crystalline anti-htnfalpha antibodies

Publications (1)

Publication Number Publication Date
BRPI0717335A2 true BRPI0717335A2 (pt) 2013-12-10

Family

ID=39364990

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0717335-0A2A BRPI0717335A2 (pt) 2006-10-27 2007-10-25 Anticorpos anti-htnfalfa cristalinos

Country Status (21)

Country Link
US (4) US8034906B2 (pt)
EP (2) EP2684895A1 (pt)
JP (2) JP2010507670A (pt)
KR (2) KR20090101893A (pt)
CN (2) CN101616932A (pt)
AR (1) AR063429A1 (pt)
AU (1) AU2007318120B2 (pt)
BR (1) BRPI0717335A2 (pt)
CA (1) CA2667655A1 (pt)
CL (1) CL2007003094A1 (pt)
ES (1) ES2442258T3 (pt)
IL (1) IL198223A (pt)
MX (1) MX2009004351A (pt)
NZ (3) NZ613356A (pt)
PE (2) PE20120663A1 (pt)
RU (2) RU2486296C2 (pt)
SG (1) SG176427A1 (pt)
TW (2) TWI417302B (pt)
UY (1) UY30662A1 (pt)
WO (1) WO2008057240A2 (pt)
ZA (1) ZA201306383B (pt)

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US20090280065A1 (en) * 2006-04-10 2009-11-12 Willian Mary K Uses and Compositions for Treatment of Psoriasis
PL218992B1 (pl) * 2002-07-19 2015-02-27 Abbott Biotech Ltd Neutralizujące o wysokim powinowactwie izolowane ludzkie przeciwciało anty-TNFα, zastosowanie tego przeciwciała, kryształ zawierający ludzkie przeciwciało anty-TNFα i preparat zawierający ten kryształ
US20040033228A1 (en) 2002-08-16 2004-02-19 Hans-Juergen Krause Formulation of human antibodies for treating TNF-alpha associated disorders
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TWI439284B (zh) 2004-04-09 2014-06-01 艾伯維生物技術有限責任公司 用於治療ＴＮＦα相關失調症之多重可變劑量療法
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WO2006041970A2 (en) * 2004-10-08 2006-04-20 Abbott Biotechnology Ltd. Treatment of respiratory syncytial virus (rsv) infection
KR101465456B1 (ko) 2005-05-16 2014-11-27 애브비 바이오테크놀로지 리미티드 미란성 다발관절염의 치료를 위한 ｔｎｆ 억제제의 용도
WO2006138181A2 (en) 2005-06-14 2006-12-28 Amgen Inc. Self-buffering protein formulations
PT1948235E (pt) 2005-11-01 2013-11-26 Abbvie Biotechnology Ltd Métodos de determinação da eficácia de adalimumab em sujeitos com espondilite anquilosante, utilizando ctx-ii e mmp3 como biomarcadores
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US8772458B2 (en) 2014-07-08
HK1129400A1 (en) 2009-11-27
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EP2684895A1 (en) 2014-01-15
RU2013103322A (ru) 2014-07-27
EP2089428A2 (en) 2009-08-19
US8034906B2 (en) 2011-10-11
RU2009119988A (ru) 2010-12-10
IL198223A0 (en) 2011-08-01
AU2007318120B2 (en) 2013-07-25
AU2007318120A1 (en) 2008-05-15
AR063429A1 (es) 2009-01-28
US8436149B2 (en) 2013-05-07
SG176427A1 (en) 2011-12-29
TW200835699A (en) 2008-09-01
US20150183863A1 (en) 2015-07-02
US20120251550A1 (en) 2012-10-04
KR20090101893A (ko) 2009-09-29
MX2009004351A (es) 2009-05-12
CN101616932A (zh) 2009-12-30
KR20150002896A (ko) 2015-01-07
UY30662A1 (es) 2008-05-31
EP2089428B1 (en) 2013-11-20
NZ613356A (en) 2015-02-27
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