BRPI0719183A2 - Tratamento com antiarrítmicos e ácidos graxos de ômega-3 e um produto de combinação destes - Google Patents

Tratamento com antiarrítmicos e ácidos graxos de ômega-3 e um produto de combinação destes Download PDF

Info

Publication number: BRPI0719183A2
Authority: BR; Brazil
Prior art keywords: omega; pharmaceutical composition; antiarrhythmic agents; fatty acids; composition according
Prior art date: 2006-10-13

Application number

BRPI0719183-9A

Other languages

English (en)

Portuguese (pt)

Inventor

George Bobotas

Roelof M L Rongen

Abdel A Fawzy

Ihor Terleckyj

Original Assignee

Reliant Pharmaceuticals Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-10-13

Filing date

2007-10-15

Publication date

2014-06-03

2007-10-15 Application filed by Reliant Pharmaceuticals Inc filed Critical Reliant Pharmaceuticals Inc

2014-06-03 Publication of BRPI0719183A2 publication Critical patent/BRPI0719183A2/pt

Links

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229920001285 xanthan gum Polymers 0.000 description 1
229940082509 xanthan gum Drugs 0.000 description 1
239000005019 zein Substances 0.000 description 1
229940093612 zein Drugs 0.000 description 1
PAPBSGBWRJIAAV-UHFFFAOYSA-N ε-Caprolactone Chemical compound O=C1CCCCCO1 PAPBSGBWRJIAAV-UHFFFAOYSA-N 0.000 description 1

Classifications

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- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
- A—HUMAN NECESSITIES
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/49—Cinchonan derivatives, e.g. quinine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4891—Coated capsules; Multilayered drug free capsule shells
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Urology & Nephrology (AREA)
Hematology (AREA)
Hospice & Palliative Care (AREA)
Diabetes (AREA)
Vascular Medicine (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Obesity (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)

BRPI0719183-9A 2006-10-13 2007-10-15 Tratamento com antiarrítmicos e ácidos graxos de ômega-3 e um produto de combinação destes BRPI0719183A2 (pt)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US85129406P	2006-10-13	2006-10-13
US60/851.294		2006-10-13
PCT/US2007/021963 WO2008063323A2 (en)	2006-10-13	2007-10-15	Treatment with antiarrhythmics and omega-3 fatty acids and a combination product thereof

Publications (1)

Publication Number	Publication Date
BRPI0719183A2 true BRPI0719183A2 (pt)	2014-06-03

Family

ID=39430253

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0719183-9A BRPI0719183A2 (pt)	2006-10-13	2007-10-15	Tratamento com antiarrítmicos e ácidos graxos de ômega-3 e um produto de combinação destes

Country Status (10)

Country	Link
EP (1)	EP2083802A2 (de)
JP (1)	JP2010506841A (de)
KR (1)	KR20090086078A (de)
CN (1)	CN101557805A (de)
AU (1)	AU2007322291A1 (de)
BR (1)	BRPI0719183A2 (de)
CA (1)	CA2672876A1 (de)
EA (1)	EA200970374A1 (de)
MX (1)	MX2009003928A (de)
WO (1)	WO2008063323A2 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US8343753B2 (en)	2007-11-01	2013-01-01	Wake Forest University School Of Medicine	Compositions, methods, and kits for polyunsaturated fatty acids from microalgae
US8592439B2 (en) *	2008-08-07	2013-11-26	Spa Societa Prodotti Antibiotici S.P.A.	Long-term treatment of symptomatic heart failure
CN107233337A (zh) *	2009-04-29	2017-10-10	阿马里纳药物爱尔兰有限公司	含有epa和心血管剂的药物组合物以及使用其的方法
MX377553B (es) *	2009-04-29	2025-03-10	Amarin Pharma Inc	Composicion farmaceutica estable y metodos de uso de la misma.
BRPI1011883A2 (pt)	2009-06-15	2016-09-13	Amarin Pharma Inc	uso de composições para redução de triglicerídeos sem elevar os níveis de o ldl-c em um paciente sob o tratamento concomitante com estatina
ES2363964B1 (es)	2009-11-20	2012-08-22	Gp Pharm, S.A.	Cápsulas de principios activos farmacéuticos y ésteres de ácidos grasos poliinsaturados.
ES2363965B1 (es)	2009-11-20	2013-01-24	Gp Pharm S.A.	Cápsulas de principios activos betabloqueantes y ésteres de ácidos grasos poliinsaturados.
CN102188417A (zh) *	2010-03-19	2011-09-21	江苏恒瑞医药股份有限公司	决奈达隆药物组合物
FR2967067A1 (fr)	2010-11-10	2012-05-11	Sanofi Aventis	Composition pharmaceutique et forme galenique a base de dronedarone et son procede de preparation
WO2013040507A1 (en) *	2011-09-15	2013-03-21	Omthera Pharmaceuticals, Inc.	Methods and compositions for treating, reversing, inhibiting or preventing resistance to antiplatelet therapy
WO2013116738A1 (en) *	2012-02-03	2013-08-08	Cardeus Pharmaceuticals, Inc.	Drug formulations
CA2874455C (en)	2012-05-22	2016-10-11	Kuhnil Pharm. Co., Ltd.	Multilayer coating form of orally administered pharmaceutical composition containing omega-3 fatty acid or alkyl ester thereof and statin based drug
TR201503136A2 (tr) *	2015-03-16	2016-09-21	Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi	Dronedaron ve esansiyel yağ asitlerinin farmasötik kompozisyonları.
WO2017083397A1 (en) *	2015-11-09	2017-05-18	Cayo Max A	Cardiac glycosides for the treatment of hypercholesterolemia
WO2017139757A1 (en) *	2016-02-12	2017-08-17	The General Hospital Corporation	Targeting macrophages to modulate electrical conduction in the heart
ES2870106T3 (es)	2017-05-05	2021-10-26	Zealand Pharma As	Moduladores de la comunicación intercelular de uniones comunicantes y su uso para el tratamiento de la enfermedad del ojo diabético
WO2019204326A1 (en) *	2018-04-16	2019-10-24	Alsar Ltd Partnership	Compositions and methods for sustained release of flecainide
MA50490A (fr)	2018-09-24	2020-09-02	Amarin Pharmaceuticals Ie Ltd	Procédés de réduction du risque d'événements cardiovasculaires chez un sujet
CA3160676A1 (en)	2019-11-12	2021-05-20	Amarin Pharmaceuticals Ireland Limited	Methods of reducing the risk of cardiovascular events in a subject with atrial fibrillation and/or atrial flutter
US11986452B2 (en)	2021-04-21	2024-05-21	Amarin Pharmaceuticals Ireland Limited	Methods of reducing the risk of heart failure

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2893866B2 (ja) *	1990-05-25	1999-05-24	日本油脂株式会社	抗不整脈薬
US5840329A (en) *	1997-05-15	1998-11-24	Bioadvances Llc	Pulsatile drug delivery system
GB0120415D0 (en) *	2001-08-22	2001-10-17	Isis Innovation	Palatable high fat composition
ITMI20020731A1 (it) *	2002-04-08	2003-10-08	Ibsa Inst Biochimique Sa	Composizioni farmaceutiche per acido acetilsalicilico e oli omega-3

2007
- 2007-10-15 JP JP2009532459A patent/JP2010506841A/ja active Pending
- 2007-10-15 EA EA200970374A patent/EA200970374A1/ru unknown
- 2007-10-15 WO PCT/US2007/021963 patent/WO2008063323A2/en not_active Ceased
- 2007-10-15 BR BRPI0719183-9A patent/BRPI0719183A2/pt not_active IP Right Cessation
- 2007-10-15 MX MX2009003928A patent/MX2009003928A/es not_active Application Discontinuation
- 2007-10-15 KR KR1020097009699A patent/KR20090086078A/ko not_active Withdrawn
- 2007-10-15 EP EP07870787A patent/EP2083802A2/de not_active Withdrawn
- 2007-10-15 AU AU2007322291A patent/AU2007322291A1/en not_active Abandoned
- 2007-10-15 CA CA002672876A patent/CA2672876A1/en not_active Abandoned
- 2007-10-15 CN CNA2007800460906A patent/CN101557805A/zh active Pending

Also Published As

Publication number	Publication date
KR20090086078A (ko)	2009-08-10
AU2007322291A1 (en)	2008-05-29
WO2008063323A3 (en)	2008-12-31
JP2010506841A (ja)	2010-03-04
MX2009003928A (es)	2009-09-21
EA200970374A1 (ru)	2009-10-30
WO2008063323A2 (en)	2008-05-29
EP2083802A2 (de)	2009-08-05
CA2672876A1 (en)	2008-05-29
CN101557805A (zh)	2009-10-14

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Date	Code	Title	Description
2014-08-26	B08L	Patent application lapsed because of non payment of annual fee [chapter 8.12 patent gazette]	Free format text: REFERENTE AO NAO RECOLHIMENTO DAS 4A, 5A, 6A E 7A ANUIDADES.
2020-11-10	B08I	Application fees: publication cancelled [chapter 8.9 patent gazette]	Free format text: ANULADA A PUBLICACAO CODIGO 8.12 NA RPI NO 2277 DE 26/08/2014 POR TER SIDO INDEVIDA.
2020-11-17	B08F	Application fees: application dismissed [chapter 8.6 patent gazette]	Free format text: REFERENTE AS 4A, 5A, 6A, 7A, 8A, 9A, 10A, 11A, 12A E 13A ANUIDADES.
2021-03-09	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2602 DE 17-11-2020 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

Publication	Publication Date	Title
WO2008063323A2 (en)	2008-05-29	Treatment with antiarrhythmics and omega-3 fatty acids and a combination product thereof
US9370493B2 (en)	2016-06-21	Coated capsules and tablets of a fatty acid oil mixture
US20070036862A1 (en)	2007-02-15	Treatment with azetidinone-based cholesterol absorption inhibitors and omega-3 fatty acids and a combination product thereof
US20070196465A1 (en)	2007-08-23	Treatment with dihydropyridine calcium channel blockers and omega-3 fatty acids and a combination product thereof
US20140004186A1 (en)	2014-01-02	Compositions comprising a fatty acid oil mixture comprising epa and dha in free acid form, a surfactant, and a statin
WO2008115529A1 (en)	2008-09-25	Compositions comprising omega-3 fatty acids and cetp inhibitors
US20140017308A1 (en)	2014-01-16	Compositions comprising a fatty acid oil mixture, a free fatty acid, and a statin
JP2013508348A5 (de)	2017-02-02
EP2081550A2 (de)	2009-07-29	Beschichtung von kapseln mit pharmazeutischen wirkstoffen
WO2008088808A1 (en)	2008-07-24	Treatment with non-steroidal anti-inflammatory drugs and omega-3 fatty acids, and a combination product thereof
WO2008112227A1 (en)	2008-09-18	Treatment with nicorandil and omega-3 fatty acids, and a combination product thereof