BRPI0719183A2 - Tratamento com antiarrítmicos e ácidos graxos de ômega-3 e um produto de combinação destes - Google Patents

Tratamento com antiarrítmicos e ácidos graxos de ômega-3 e um produto de combinação destes Download PDF

Info

Publication number: BRPI0719183A2
Authority: BR; Brazil
Prior art keywords: omega; pharmaceutical composition; antiarrhythmic agents; fatty acids; composition according
Prior art date: 2006-10-13

Application number

BRPI0719183-9A

Other languages

English (en)

Portuguese (pt)

Inventor

George Bobotas

Roelof M L Rongen

Abdel A Fawzy

Ihor Terleckyj

Original Assignee

Reliant Pharmaceuticals Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-10-13

Filing date

2007-10-15

Publication date

2014-06-03

2007-10-15 Application filed by Reliant Pharmaceuticals Inc filed Critical Reliant Pharmaceuticals Inc

2014-06-03 Publication of BRPI0719183A2 publication Critical patent/BRPI0719183A2/pt

Links

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229920001285 xanthan gum Polymers 0.000 description 1
229940082509 xanthan gum Drugs 0.000 description 1
239000005019 zein Substances 0.000 description 1
229940093612 zein Drugs 0.000 description 1
PAPBSGBWRJIAAV-UHFFFAOYSA-N ε-Caprolactone Chemical compound O=C1CCCCCO1 PAPBSGBWRJIAAV-UHFFFAOYSA-N 0.000 description 1

Classifications

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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
- A—HUMAN NECESSITIES
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/49—Cinchonan derivatives, e.g. quinine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4891—Coated capsules; Multilayered drug free capsule shells
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Urology & Nephrology (AREA)
Obesity (AREA)
Hematology (AREA)
Vascular Medicine (AREA)
Hospice & Palliative Care (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Diabetes (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)

BRPI0719183-9A 2006-10-13 2007-10-15 Tratamento com antiarrítmicos e ácidos graxos de ômega-3 e um produto de combinação destes BRPI0719183A2 (pt)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US85129406P	2006-10-13	2006-10-13
US60/851.294		2006-10-13
PCT/US2007/021963 WO2008063323A2 (fr)	2006-10-13	2007-10-15	Traitement à base d'anti-arythmisants et d'acides gras oméga-3 et produit mixte obtenu à partir de ceux-ci

Publications (1)

Publication Number	Publication Date
BRPI0719183A2 true BRPI0719183A2 (pt)	2014-06-03

Family

ID=39430253

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0719183-9A BRPI0719183A2 (pt)	2006-10-13	2007-10-15	Tratamento com antiarrítmicos e ácidos graxos de ômega-3 e um produto de combinação destes

Country Status (10)

Country	Link
EP (1)	EP2083802A2 (fr)
JP (1)	JP2010506841A (fr)
KR (1)	KR20090086078A (fr)
CN (1)	CN101557805A (fr)
AU (1)	AU2007322291A1 (fr)
BR (1)	BRPI0719183A2 (fr)
CA (1)	CA2672876A1 (fr)
EA (1)	EA200970374A1 (fr)
MX (1)	MX2009003928A (fr)
WO (1)	WO2008063323A2 (fr)

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US8343753B2 (en)	2007-11-01	2013-01-01	Wake Forest University School Of Medicine	Compositions, methods, and kits for polyunsaturated fatty acids from microalgae
EA020237B1 (ru) *	2008-08-07	2014-09-30	СПА СОЧЬЕТА'ПРОДОТТИ АНТИБИОТИЧИ С.п.А.	Способ снижения смертности от сердечно-сосудистых событий
SG175390A1 (en) *	2009-04-29	2011-12-29	Amarin Corp Plc	Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same
PT3278665T (pt) *	2009-04-29	2020-11-19	Amarin Pharmaceuticals Ie Ltd	Composição farmacêutica estável e métodos de utilização das mesmas
CN106074486A (zh)	2009-06-15	2016-11-09	阿马里纳药物爱尔兰有限公司	在相伴他汀类疗法的对象中降低甘油三酯、没有增加ldl‑c水平的组合物和方法
ES2363965B1 (es)	2009-11-20	2013-01-24	Gp Pharm S.A.	Cápsulas de principios activos betabloqueantes y ésteres de ácidos grasos poliinsaturados.
ES2363964B1 (es)	2009-11-20	2012-08-22	Gp Pharm, S.A.	Cápsulas de principios activos farmacéuticos y ésteres de ácidos grasos poliinsaturados.
CN102188417A (zh) *	2010-03-19	2011-09-21	江苏恒瑞医药股份有限公司	决奈达隆药物组合物
FR2967067A1 (fr)	2010-11-10	2012-05-11	Sanofi Aventis	Composition pharmaceutique et forme galenique a base de dronedarone et son procede de preparation
US20130095179A1 (en) *	2011-09-15	2013-04-18	Omthera Pharmaceuticals, Inc.	Methods and compositions for treating, reversing, inhibiting or preventing resistance to antiplatelet therapy
WO2013116738A1 (fr) *	2012-02-03	2013-08-08	Cardeus Pharmaceuticals, Inc.	Formulations de médicament
KR101335365B1 (ko)	2012-05-22	2013-12-02	건일제약 주식회사	오메가-3 지방산 또는 그의 알킬 에스테르 및 스타틴계 약물을 함유하는 다층코팅 형태의 경구투여용 약학 조성물
TR201503136A2 (tr) *	2015-03-16	2016-09-21	Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi	Dronedaron ve esansiyel yağ asitlerinin farmasötik kompozisyonları.
WO2017083397A1 (fr) *	2015-11-09	2017-05-18	Cayo Max A	Glycosides cardiaques pour traiter l'hypercholestérolémie
WO2017139757A1 (fr) *	2016-02-12	2017-08-17	The General Hospital Corporation	Ciblage de macrophages pour moduler la conduction électrique dans le coeur
CN110709096B (zh)	2017-05-05	2023-10-31	泽兰德制药公司	细胞间隙连接通讯调节剂及其在糖尿病性眼病治疗中的应用
WO2019204326A1 (fr) *	2018-04-16	2019-10-24	Alsar Ltd Partnership	Compositions et procédés pour la libération prolongée de flécaïnide
KR20210110890A (ko)	2018-09-24	2021-09-09	애머린 파마슈티칼스 아일랜드 리미티드	대상체에서 심혈관 사건의 위험도를 감소시키는 방법
US12427134B2 (en)	2019-11-12	2025-09-30	Amarin Pharmaceuticals Ireland Limited	Methods of reducing the risk of cardiovascular events in a subject with atrial fibrillation and/or atrial flutter
AU2022263358A1 (en)	2021-04-21	2023-11-30	Amarin Pharmaceuticals Ireland Limited	Methods of reducing the risk of heart failure

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JP2893866B2 (ja) *	1990-05-25	1999-05-24	日本油脂株式会社	抗不整脈薬
US5840329A (en) *	1997-05-15	1998-11-24	Bioadvances Llc	Pulsatile drug delivery system
GB0120415D0 (en) *	2001-08-22	2001-10-17	Isis Innovation	Palatable high fat composition
ITMI20020731A1 (it) *	2002-04-08	2003-10-08	Ibsa Inst Biochimique Sa	Composizioni farmaceutiche per acido acetilsalicilico e oli omega-3

2007
- 2007-10-15 JP JP2009532459A patent/JP2010506841A/ja active Pending
- 2007-10-15 BR BRPI0719183-9A patent/BRPI0719183A2/pt not_active IP Right Cessation
- 2007-10-15 EP EP07870787A patent/EP2083802A2/fr not_active Withdrawn
- 2007-10-15 WO PCT/US2007/021963 patent/WO2008063323A2/fr not_active Ceased
- 2007-10-15 KR KR1020097009699A patent/KR20090086078A/ko not_active Withdrawn
- 2007-10-15 AU AU2007322291A patent/AU2007322291A1/en not_active Abandoned
- 2007-10-15 MX MX2009003928A patent/MX2009003928A/es not_active Application Discontinuation
- 2007-10-15 CA CA002672876A patent/CA2672876A1/fr not_active Abandoned
- 2007-10-15 CN CNA2007800460906A patent/CN101557805A/zh active Pending
- 2007-10-15 EA EA200970374A patent/EA200970374A1/ru unknown

Also Published As

Publication number	Publication date
KR20090086078A (ko)	2009-08-10
WO2008063323A3 (fr)	2008-12-31
CN101557805A (zh)	2009-10-14
JP2010506841A (ja)	2010-03-04
CA2672876A1 (fr)	2008-05-29
AU2007322291A1 (en)	2008-05-29
WO2008063323A2 (fr)	2008-05-29
MX2009003928A (es)	2009-09-21
EP2083802A2 (fr)	2009-08-05
EA200970374A1 (ru)	2009-10-30

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2020-11-10	B08I	Application fees: publication cancelled [chapter 8.9 patent gazette]	Free format text: ANULADA A PUBLICACAO CODIGO 8.12 NA RPI NO 2277 DE 26/08/2014 POR TER SIDO INDEVIDA.
2020-11-17	B08F	Application fees: application dismissed [chapter 8.6 patent gazette]	Free format text: REFERENTE AS 4A, 5A, 6A, 7A, 8A, 9A, 10A, 11A, 12A E 13A ANUIDADES.
2021-03-09	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2602 DE 17-11-2020 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

Publication	Publication Date	Title
BRPI0719183A2 (pt)	2014-06-03	Tratamento com antiarrítmicos e ácidos graxos de ômega-3 e um produto de combinação destes
US9370493B2 (en)	2016-06-21	Coated capsules and tablets of a fatty acid oil mixture
US20070036862A1 (en)	2007-02-15	Treatment with azetidinone-based cholesterol absorption inhibitors and omega-3 fatty acids and a combination product thereof
US20070196465A1 (en)	2007-08-23	Treatment with dihydropyridine calcium channel blockers and omega-3 fatty acids and a combination product thereof
US20140004186A1 (en)	2014-01-02	Compositions comprising a fatty acid oil mixture comprising epa and dha in free acid form, a surfactant, and a statin
US20140017308A1 (en)	2014-01-16	Compositions comprising a fatty acid oil mixture, a free fatty acid, and a statin
JP2013508348A5 (fr)	2017-02-02
WO2008088808A1 (fr)	2008-07-24	Traitement par médicaments anti-inflammatoires non stéroïdiens et acides gras oméga-3, et produit de combinaison de ceux-ci
WO2008112227A1 (fr)	2008-09-18	Traitement par nicorandil et acides gras oméga 3 et produit combinant ceux-ci