BRPI0719352A2 - inibidores de enzima diacilglicerol o-aciltransferase tipo 1 - Google Patents

inibidores de enzima diacilglicerol o-aciltransferase tipo 1

Info

Publication number: BRPI0719352A2
Authority: BR; Brazil
Prior art keywords: diacylglycerol; enzyme inhibitors; acyltransferase enzyme; inhibitors type; type
Prior art date: 2006-11-29

Application number

BRPI0719352A

Other languages

English (en)

Inventor

J Souers Andrew

X Liu Bo

Zhao Gang

Gao Ju

R Kym Philip

R Iyengar Rajesh

Matthew Hansen Todd

Yeh Vince

Pei Zhonghua

Original Assignee

Abbott Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-11-29

Filing date

2007-11-26

Publication date

2017-10-24

2007-11-26 Application filed by Abbott Lab filed Critical Abbott Lab

2017-10-24 Publication of BRPI0719352A2 publication Critical patent/BRPI0719352A2/pt

Links

102000002148 Diacylglycerol O-acyltransferase Human genes 0.000 title 1
108010001348 Diacylglycerol O-acyltransferase Proteins 0.000 title 1
239000002532 enzyme inhibitor Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/42—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by carboxyl groups
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- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
- C07C59/54—Unsaturated compounds containing hydroxy or O-metal groups containing six-membered aromatic rings and other rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
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- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/18—One oxygen or sulfur atom
- C07D231/20—One oxygen atom attached in position 3 or 5
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/48—Nitrogen atoms not forming part of a nitro radical
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/40—Unsubstituted amino or imino radicals
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

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Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Diabetes (AREA)
Hematology (AREA)
Cardiology (AREA)
Obesity (AREA)
Heart & Thoracic Surgery (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Physical Education & Sports Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Emergency Medicine (AREA)
Vascular Medicine (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Urology & Nephrology (AREA)
Hospice & Palliative Care (AREA)
Gynecology & Obstetrics (AREA)
Pregnancy & Childbirth (AREA)
Child & Adolescent Psychology (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Thiazole And Isothizaole Compounds (AREA)

BRPI0719352A 2006-11-29 2007-11-26 inibidores de enzima diacilglicerol o-aciltransferase tipo 1 BRPI0719352A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US86769506P	2006-11-29	2006-11-29
PCT/US2007/085543 WO2008067257A2 (en)	2006-11-29	2007-11-26	Inhibitors of diacylglycerol o-acyltransferase type 1 enzyme

Publications (1)

Publication Number	Publication Date
BRPI0719352A2 true BRPI0719352A2 (pt)	2017-10-24

Family

ID=39468633

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0719352A BRPI0719352A2 (pt)	2006-11-29	2007-11-26	inibidores de enzima diacilglicerol o-aciltransferase tipo 1

Country Status (17)

Country	Link
US (2)	US8202878B2 (pt)
EP (1)	EP2117526B1 (pt)
JP (1)	JP2010511058A (pt)
KR (1)	KR20090091315A (pt)
CN (1)	CN101636155A (pt)
AU (1)	AU2007325350B2 (pt)
BR (1)	BRPI0719352A2 (pt)
CA (1)	CA2670736A1 (pt)
ES (1)	ES2421326T3 (pt)
IL (1)	IL198979A (pt)
MX (1)	MX2009005691A (pt)
NZ (2)	NZ577112A (pt)
RU (1)	RU2474576C2 (pt)
SG (1)	SG177144A1 (pt)
TW (1)	TW200831511A (pt)
WO (1)	WO2008067257A2 (pt)
ZA (1)	ZA200903692B (pt)

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BRPI0519058A2 (pt)	2004-12-14	2008-12-23	Astrazeneca Ab	composto ou um sal prà-droga farmaceuticamente aceitÁvel do mesmo, mÉtodos para produzir uma inibiÇço da atividade de dgat1 e para tratar diabete melito e/ou obesidade em um animal de sangue quente, uso de um composto, composiÇço farmacÊutica, e, processo para preparar um composto
AR058562A1 (es)	2005-12-22	2008-02-13	Astrazeneca Ab	Derivados de pirimido [4,5 b] (1,4) oxazinas , procedimientos de obtencion y su uso como inhibidores de acetil coa y dgat 1
PT2402319T (pt) *	2006-03-31	2017-12-11	Novartis Ag	Inibidores de dgat
AU2007266796B2 (en)	2006-05-30	2011-02-10	Astrazeneca Ab	Substituted 5-phenylamino-1,3,4-oxadiazol-2-ylcarbonylamino-4-phenoxy-cyclohexane carboxylic acid as inhibitors of acetyl coenzyme A diacylglycerol acyltransferase
MX2008015226A (es)	2006-05-30	2008-12-12	Astrazeneca Ab	Derivados de 1,3,4-oxadiazol como inhibidores de dgat1.
CA2655604C (en)	2006-06-23	2016-08-09	Abbott Laboratories	Cyclopropyl amine derivatives
US9108948B2 (en)	2006-06-23	2015-08-18	Abbvie Inc.	Cyclopropyl amine derivatives
NZ580662A (en) *	2007-04-30	2012-01-12	Abbott Lab	Inhibitors of diacylglycerol o-acyltransferase type 1 enzyme used in manufacture of medicament for treatment of diabetes or lipid associated disorders
AR066169A1 (es)	2007-09-28	2009-07-29	Novartis Ag	Derivados de benzo-imidazoles, utiles para trastornos asociados con la actividad de dgat
AR069802A1 (es)	2007-12-20	2010-02-17	Astrazeneca Ab	Compuestos de carbamoilo como inhibidores de dgat1 190
EP2341924A4 (en)	2008-10-02	2013-01-23	David Gladstone Inst	METHOD FOR THE TREATMENT OF HEPATITIS C VIRUS INFECTIONS
JP2012520887A (ja)	2009-03-18	2012-09-10	シェーリングコーポレイション	ジアシルグリセロールアシルトランスフェラーゼの阻害剤としての二環式化合物
EP2408774B1 (en)	2009-03-20	2014-11-26	Metabasis Therapeutics, Inc.	Inhibitors of diacylglycerol o-acyltransferase 1(dgat-1) and uses thereof
US9186353B2 (en)	2009-04-27	2015-11-17	Abbvie Inc.	Treatment of osteoarthritis pain
MX2011014018A (es)	2009-06-19	2012-02-22	Astrazeneca Ab	Pirazincarboxamidas como inhibidores de dgati.
EP2477498A4 (en)	2009-09-14	2013-02-27	Merck Sharp & Dohme	INHIBITORS OF DIACYLGLYCEROL ACYLTRANSFERASE
US8343977B2 (en)	2009-12-30	2013-01-01	Arqule, Inc.	Substituted triazolo-pyrimidine compounds
US8853390B2 (en)	2010-09-16	2014-10-07	Abbvie Inc.	Processes for preparing 1,2-substituted cyclopropyl derivatives
AR083417A1 (es)	2010-10-14	2013-02-21	Novartis Ag	Composiciones farmaceuticas que contienen un dgat1 inhibidor
JP5629380B2 (ja)	2010-12-17	2014-11-19	田辺三菱製薬株式会社	連続芳香環式化合物
US9271969B2 (en)	2012-02-07	2016-03-01	Kainos Medicine, Inc.	Compounds as inhibitors of diacylglycerol O-acyltransferase type 1 enzyme
ES2690315T3 (es) *	2012-06-15	2018-11-20	Mitsubishi Tanabe Pharma Corporation	Compuestos de imidazol y triazol como inhibidores de DGAT-1
WO2014081996A1 (en) *	2012-11-23	2014-05-30	Glaxosmithkline Llc	Novel compounds as diacylglycerol acyltransferase inhibitors
WO2014081995A1 (en) *	2012-11-23	2014-05-30	Glaxosmithkline Llc	Novel compounds as diacylglycerol acyltransferase inhibitors
CN111269111B (zh) *	2020-01-22	2023-01-03	杭州盛弗泰新材料科技有限公司	一种4-氯甲酰基联苯的合成方法

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2007
- 2007-11-26 NZ NZ577112A patent/NZ577112A/en not_active IP Right Cessation
- 2007-11-26 RU RU2009124450/04A patent/RU2474576C2/ru not_active IP Right Cessation
- 2007-11-26 SG SG2011088143A patent/SG177144A1/en unknown
- 2007-11-26 BR BRPI0719352A patent/BRPI0719352A2/pt not_active IP Right Cessation
- 2007-11-26 EP EP07854765A patent/EP2117526B1/en active Active
- 2007-11-26 NZ NZ597247A patent/NZ597247A/xx not_active IP Right Cessation
- 2007-11-26 WO PCT/US2007/085543 patent/WO2008067257A2/en not_active Ceased
- 2007-11-26 ES ES07854765T patent/ES2421326T3/es active Active
- 2007-11-26 CA CA002670736A patent/CA2670736A1/en not_active Abandoned
- 2007-11-26 MX MX2009005691A patent/MX2009005691A/es active IP Right Grant
- 2007-11-26 KR KR1020097013320A patent/KR20090091315A/ko not_active Ceased
- 2007-11-26 CN CN200780050654A patent/CN101636155A/zh active Pending
- 2007-11-26 AU AU2007325350A patent/AU2007325350B2/en not_active Ceased
- 2007-11-26 JP JP2009539428A patent/JP2010511058A/ja active Pending
- 2007-11-28 TW TW096145208A patent/TW200831511A/zh unknown
- 2007-11-29 US US11/947,005 patent/US8202878B2/en not_active Expired - Fee Related
2009
- 2009-05-26 IL IL198979A patent/IL198979A/en not_active IP Right Cessation
- 2009-05-27 ZA ZA2009/03692A patent/ZA200903692B/en unknown
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Also Published As

Publication number	Publication date
IL198979A (en)	2013-09-30
NZ577112A (en)	2012-03-30
US8586594B2 (en)	2013-11-19
US20080182861A1 (en)	2008-07-31
JP2010511058A (ja)	2010-04-08
CN101636155A (zh)	2010-01-27
US8202878B2 (en)	2012-06-19
KR20090091315A (ko)	2009-08-27
NZ597247A (en)	2013-06-28
EP2117526A4 (en)	2011-07-27
RU2009124450A (ru)	2011-01-10
SG177144A1 (en)	2012-01-30
WO2008067257A3 (en)	2008-07-24
RU2474576C2 (ru)	2013-02-10
HK1133596A1 (en)	2010-04-01
ES2421326T3 (es)	2013-08-30
WO2008067257A8 (en)	2009-06-25
MX2009005691A (es)	2009-08-07
ZA200903692B (en)	2012-11-28
AU2007325350B2 (en)	2012-09-20
AU2007325350A1 (en)	2008-06-05
WO2008067257A2 (en)	2008-06-05
EP2117526B1 (en)	2013-04-03
CA2670736A1 (en)	2008-06-05
TW200831511A (en)	2008-08-01
US20120238581A1 (en)	2012-09-20
IL198979A0 (en)	2010-02-17
EP2117526A2 (en)	2009-11-18

Legal Events

Date	Code	Title	Description
2017-10-31	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
2018-02-20	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]
2018-05-02	B25B	Requested transfer of rights rejected	Owner name: ABBOTT LABORATORIES (US)

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