BRPI0719549B8 - composição para administração de princípios biologicamente ativos no âmbito ginecológico e retal, e usos para as mesmas - Google Patents

composição para administração de princípios biologicamente ativos no âmbito ginecológico e retal, e usos para as mesmas

Info

Publication number
BRPI0719549B8
BRPI0719549B8 BRPI0719549A BRPI0719549A BRPI0719549B8 BR PI0719549 B8 BRPI0719549 B8 BR PI0719549B8 BR PI0719549 A BRPI0719549 A BR PI0719549A BR PI0719549 A BRPI0719549 A BR PI0719549A BR PI0719549 B8 BRPI0719549 B8 BR PI0719549B8
Authority
BR
Brazil
Prior art keywords
composition
gynecological
rectal
administration
biologically active
Prior art date
Application number
BRPI0719549A
Other languages
English (en)
Inventor
Paolo Strozzi Gian
Mogna Luca
Original Assignee
Probiotical Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Probiotical Spa filed Critical Probiotical Spa
Publication of BRPI0719549A2 publication Critical patent/BRPI0719549A2/pt
Publication of BRPI0719549B1 publication Critical patent/BRPI0719549B1/pt
Publication of BRPI0719549B8 publication Critical patent/BRPI0719549B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0031—Rectum, anus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/745—Bifidobacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gynecology & Obstetrics (AREA)
  • Organic Chemistry (AREA)
  • Reproductive Health (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Endocrinology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

composição para administração de princípios biologicamente ativos no âmbito ginecológicos e retal, e usos para as mesmas. a presente invenção refere-se a uma composição para a administração de substâncias biologicamente ativas no âmbito ginecológico e retal, bem como aos usos da referida composição. a referida composição apresenta características tecnológicas e de estabilidade particularmente favoráveis do produto final, sobretudo com respeito à viscosidade e após sua dissolução/ressuspensão em um meio líquido hidrófilo que permite melhor adesão e contato direto das bactérias com as mucosas tratadas. a referida composição inclui um agente viscosante específico selecionado dentre o grupo das gomas, que pode desempenhar uma função prebiótica importante contribuindo de maneira significativa para o crescimento e colonização correta da cultura probiótica, formando assim um sistema simbiótico perfeito.
BRPI0719549A 2006-11-28 2007-11-12 composição para administração de princípios biologicamente ativos no âmbito ginecológico e retal, e usos para as mesmas BRPI0719549B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT002286A ITMI20062286A1 (it) 2006-11-28 2006-11-28 Una composizione per la somministrazione di principi biologicamente attivi in ambito ginecologico e rettale nonche' i suoi usi
ITMI2006A002286 2006-11-28
PCT/IB2007/003491 WO2008065492A2 (en) 2006-11-28 2007-11-12 A composition for the administration of biologically active principles in gynaecologic and rectal field and uses thereof

Publications (3)

Publication Number Publication Date
BRPI0719549A2 BRPI0719549A2 (pt) 2014-01-21
BRPI0719549B1 BRPI0719549B1 (pt) 2020-05-19
BRPI0719549B8 true BRPI0719549B8 (pt) 2021-05-25

Family

ID=39468316

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0719549A BRPI0719549B8 (pt) 2006-11-28 2007-11-12 composição para administração de princípios biologicamente ativos no âmbito ginecológico e retal, e usos para as mesmas

Country Status (11)

Country Link
US (1) US20100092440A1 (pt)
EP (1) EP2120864B1 (pt)
JP (1) JP5535641B2 (pt)
BR (1) BRPI0719549B8 (pt)
CA (1) CA2670578C (pt)
DK (1) DK2120864T3 (pt)
ES (1) ES2626841T3 (pt)
IT (1) ITMI20062286A1 (pt)
PL (1) PL2120864T3 (pt)
RU (1) RU2445073C2 (pt)
WO (1) WO2008065492A2 (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1403661B1 (it) * 2011-01-28 2013-10-31 Probiotical Spa Composizione effervescente in forma solida per uso in applicazioni vaginali per il trattamento di infezioni vaginali.
ITMI20110793A1 (it) 2011-05-09 2012-11-10 Probiotical Spa Ceppi di batteri probiotici e composizione sinbiotica contenente gli stessi destinata alla alimentazione dei neonati.
ITMI20110791A1 (it) 2011-05-09 2012-11-10 Probiotical Spa Ceppi di batteri in grado di metabolizzare gli ossalati.
ITMI20110792A1 (it) 2011-05-09 2012-11-10 Probiotical Spa Ceppi di batteri appartenenti al genere bifidobacterium per uso nel trattamento della ipercolesterolemia.
ITRM20110477A1 (it) 2011-09-09 2013-03-10 Giovanni Mogna Composizione comprendente n-acetilcisteina e/o lisozima microincapsulato gastroprotetto in associazione con batteri probiotici in grado di ripristinare l'effetto barriera proprio dello stomaco che viene perso durante il trattamento farmacologico dell
ITMI20111718A1 (it) 2011-09-23 2013-03-24 Probiotical Spa Un materiale impermeabile alla umidita e allo ossigeno per confezionare prodotti dietetici, cosmetici e specialita medicinali.
WO2013113767A1 (en) * 2012-01-31 2013-08-08 Bioclin Bv Method for administration of a probiotic
ITMI20130793A1 (it) * 2013-05-14 2014-11-15 Probiotical Spa Composizione comprendente batteri lattici per uso nel trattamento preventivo e/o curativo delle cistiti ricorrenti.
ITMI20130794A1 (it) * 2013-05-14 2014-11-15 Probiotical Spa Composizione comprendente batteri lattici per uso nel trattamento preventivo e/o curativo delle vaginosi batteriche.
ITMI20130795A1 (it) * 2013-05-14 2014-11-15 Probiotical Spa Composizione comprendente batteri lattici e/o bifidobatteri per uso nel trattamento preventivo e/o curativo delle infezioni batteriche e/o delle infiammazioni del tratto urinario e/o della prostata che sono la causa di prostatiti e ipertrofia prostat
ITMI20131280A1 (it) * 2013-07-30 2015-01-31 Probiotical Spa Produzione di materie prime e prodotti finiti atossici testati mediante un metodo innovativo a base di batteri probiotici per la determinazione della tossicità verso i batteri probiotici.
EP3178469A2 (en) * 2014-08-05 2017-06-14 HPRD-Health Products Research and Development LDA Vaginal composition for the treatment of urogenital infections
ITUA20162013A1 (it) 2016-03-24 2017-09-24 Probiotical Spa Composizione a base di batteri lattici per il trattamento contemporaneo di infezioni vaginali di origine micotica e batterica.
AU2017376780B2 (en) 2016-12-15 2024-12-12 Novome Biotechnologies, Inc. Compositions and methods for modulating growth of a genetically modified gut bacterial cell
US11660321B2 (en) * 2017-01-31 2023-05-30 University-Industry Cooperation Group Of Kyung Hee University Method of treatment with lactic acid bacteria
DE20708726T1 (de) 2019-01-18 2022-01-13 Cp Kelco U.S., Inc. Präbiotische zusammensetzung und deren verwendung
CN112813011A (zh) * 2021-03-23 2021-05-18 北京宝源广通科技发展有限公司 一种干酪乳杆菌及其在制备水苏糖合生元酸奶中的应用
CN113558246B (zh) * 2021-07-21 2023-10-20 石河子大学 一种共生双歧杆菌复合微胶囊及制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK242083D0 (da) * 1983-05-27 1983-05-27 Hansens Chr Bio Syst Vaginalkapsler
JPH06101994B2 (ja) * 1989-08-16 1994-12-14 ユニコロイド株式会社 耐消化性腸内有用細菌及びその製法
DE4123330A1 (de) * 1991-07-15 1993-01-21 Gerhard Netz Verfahren zur peranalen keimapplikation
JPH05262657A (ja) * 1992-01-22 1993-10-12 Miyarisan Seibutsu Igaku Kenkyusho:Kk 酪酸菌含有液剤の製造法
US5292534A (en) * 1992-03-25 1994-03-08 Valentine Enterprises, Inc. Sustained release composition and method utilizing xanthan gum and an active ingredient
US5531989A (en) * 1994-10-28 1996-07-02 Metagenics, Inc. Immunoglobulin and fiber-containing composition for human gastrointestinal health
US6093394A (en) * 1997-04-11 2000-07-25 Gynelogix, Inc. Vaginal lactobacillus medicant
JPH1121231A (ja) * 1997-07-03 1999-01-26 Okamoto Ind Inc 水溶性潤滑剤
ATE207755T1 (de) * 1998-04-30 2001-11-15 Vesely Renata Maria Cavaliere Pharmazeutische zusammensetzungen enthaltend lactobacillus brevis und lactobacillus salivarius zur behandlung von vaginainfektionen
JP2003128588A (ja) * 2001-08-10 2003-05-08 Toray Ind Inc 多糖類含有組成物およびその用途
CA2461708C (en) * 2001-09-28 2012-08-07 Nutraceutix, Inc. Delivery system for biological component
WO2005060937A1 (en) * 2003-12-23 2005-07-07 Chr. Hansen A/S Compressed tablets comprising viable probiotic microorganisms

Also Published As

Publication number Publication date
RU2445073C2 (ru) 2012-03-20
ITMI20062286A1 (it) 2008-05-29
WO2008065492A2 (en) 2008-06-05
EP2120864B1 (en) 2017-03-22
BRPI0719549A2 (pt) 2014-01-21
ES2626841T3 (es) 2017-07-26
EP2120864A2 (en) 2009-11-25
DK2120864T3 (en) 2017-05-01
WO2008065492A3 (en) 2009-03-19
US20100092440A1 (en) 2010-04-15
PL2120864T3 (pl) 2017-08-31
JP5535641B2 (ja) 2014-07-02
RU2009121623A (ru) 2011-01-10
CA2670578C (en) 2016-01-26
CA2670578A1 (en) 2008-06-05
JP2010511033A (ja) 2010-04-08
BRPI0719549B1 (pt) 2020-05-19

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B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
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B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

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