BRPI0719923A2 - Nucleotídeos e nucleosídeos rotulados fotocliváveis e nucleotídeos e nucleosídeos rotulados e métodos para seu uso no sequenciamento de dna - Google Patents

Nucleotídeos e nucleosídeos rotulados fotocliváveis e nucleotídeos e nucleosídeos rotulados e métodos para seu uso no sequenciamento de dna

Info

Publication number
BRPI0719923A2
BRPI0719923A2 BRPI0719923-6A2A BRPI0719923A BRPI0719923A2 BR PI0719923 A2 BRPI0719923 A2 BR PI0719923A2 BR PI0719923 A BRPI0719923 A BR PI0719923A BR PI0719923 A2 BRPI0719923 A2 BR PI0719923A2
Authority
BR
Brazil
Prior art keywords
nucleosids
nucleoids
labeled
photoclivable
methods
Prior art date
Application number
BRPI0719923-6A2A
Other languages
English (en)
Inventor
Vladislav Litosh
Brian P Stupi
Michael L Metzker
Weidong Wu
Original Assignee
Lasergen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/567,193 external-priority patent/US7893227B2/en
Priority claimed from US11/567,189 external-priority patent/US7897737B2/en
Application filed by Lasergen Inc filed Critical Lasergen Inc
Publication of BRPI0719923A2 publication Critical patent/BRPI0719923A2/pt
Publication of BRPI0719923B1 publication Critical patent/BRPI0719923B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
BRPI0719923-6A 2006-12-05 2007-12-05 Métodos para sequenciamento de um ácido nucléico alvo, para conversão de um componente de ocorrência não natural em uma molécula de ácido nucléico em um componente de ocorrência natural, para terminar uma síntese de ácido nucléico, e para realizar o sequenciamento de sanger ou tipo sanger, e compostos BRPI0719923B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US11/567,189 2006-12-05
US11/567,193 US7893227B2 (en) 2006-12-05 2006-12-05 3′-OH unblocked nucleotides and nucleosides base modified with non-cleavable, terminating groups and methods for their use in DNA sequencing
US11/567,189 US7897737B2 (en) 2006-12-05 2006-12-05 3′-OH unblocked, nucleotides and nucleosides, base modified with photocleavable, terminating groups and methods for their use in DNA sequencing
US11/567,193 2006-12-05
PCT/US2007/086559 WO2008070749A2 (en) 2006-12-05 2007-12-05 Photocleavable labeled nucleotides and nucleosides and labeled nucleotides and nucleosides and methods for their use in dna sequencing

Publications (2)

Publication Number Publication Date
BRPI0719923A2 true BRPI0719923A2 (pt) 2014-03-04
BRPI0719923B1 BRPI0719923B1 (pt) 2021-08-17

Family

ID=39493724

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0719923-6A BRPI0719923B1 (pt) 2006-12-05 2007-12-05 Métodos para sequenciamento de um ácido nucléico alvo, para conversão de um componente de ocorrência não natural em uma molécula de ácido nucléico em um componente de ocorrência natural, para terminar uma síntese de ácido nucléico, e para realizar o sequenciamento de sanger ou tipo sanger, e compostos

Country Status (12)

Country Link
EP (1) EP2125856B1 (pt)
JP (1) JP5513122B2 (pt)
KR (1) KR101504640B1 (pt)
CN (1) CN102443030B (pt)
AU (1) AU2007329361B2 (pt)
BR (1) BRPI0719923B1 (pt)
CA (1) CA2670937C (pt)
IL (1) IL199051A (pt)
MX (2) MX338089B (pt)
NZ (1) NZ577303A (pt)
RU (1) RU2009121089A (pt)
WO (1) WO2008070749A2 (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7897737B2 (en) 2006-12-05 2011-03-01 Lasergen, Inc. 3′-OH unblocked, nucleotides and nucleosides, base modified with photocleavable, terminating groups and methods for their use in DNA sequencing
EA201100001A3 (ru) 2008-06-11 2013-03-29 Лейзеджен, Инк. Нуклеотиды и нуклеозиды и методы их использования в секвенировании днк
US10759824B2 (en) 2008-09-03 2020-09-01 Quantumdx Group Limited Design, synthesis and use of synthetic nucleotides comprising charge mass tags
WO2017120148A1 (en) 2016-01-04 2017-07-13 Quantumdx Group Limited Design, synthesis and use of synthetic nucleotides comprising charge mass tags
EP2321429B1 (en) 2008-09-03 2016-08-17 Quantumdx Group Limited Methods and kits for nucleic acid sequencing
MX342195B (es) 2011-09-13 2016-09-20 Lasergen Inc Nucleótidos de terminación de rápida fotodescomposición 5-metoxi, 3' -oh no bloqueados y métodos para secuenciación de ácido nucleico.
BR112014016846B1 (pt) 2012-01-13 2020-09-29 Koninklijke Philips N.V Dispositivo para o controle óptico de uma reação em etapas iterativa para determinar uma sequência de um ácido nucleico por síntese e método para o controle óptico de uma reação em etapas iterativa para determinar uma sequência de um ácido nucleico por síntese
CN103602719B (zh) * 2013-04-07 2016-06-08 北京迈基诺基因科技有限责任公司 一种基因测序方法
CN105555966B (zh) * 2013-07-31 2020-09-25 株式会社日立高新技术 核酸分析用流动池和核酸分析装置
GB201414098D0 (en) 2014-08-08 2014-09-24 Illumina Cambridge Ltd Modified nucleotide linkers
RU2582198C1 (ru) * 2014-11-20 2016-04-20 Федеральное государственное бюджетное учреждение науки Лимнологический институт Сибирского отделения Российской академии наук (ЛИН СО РАН) Аналоги природных дезоксирибонуклеозидтрифосфатов и рибонуклеозидтрифосфатов, содержащие репортёрные флуоресцентные группы, для использования в аналитической биоорганической химии
CN105001292A (zh) * 2015-07-14 2015-10-28 深圳市瀚海基因生物科技有限公司 一种光可断裂的荧光标记可逆终端化合物及其在dna或rna测序中的用途
GB201711219D0 (en) 2017-07-12 2017-08-23 Illumina Cambridge Ltd Short pendant arm linkers for nucleotides in sequencing applications
CA3125920A1 (en) 2019-01-07 2020-07-16 Agilent Technologies, Inc. Compositions and methods for genomic dna and gene expression analysis in single cells
CN110568039B (zh) * 2019-09-06 2021-05-04 中国科学院生物物理研究所 使用新型电化学传感器的氨基酸特异实时检测方法
WO2021194640A1 (en) * 2020-03-26 2021-09-30 Agilent Technologies, Inc. Methods and compositions for multistage primer extension reactions
GB2605404A (en) * 2021-03-30 2022-10-05 Sumitomo Chemical Co Sequencing method
EP4355757A1 (en) * 2021-06-17 2024-04-24 F. Hoffmann-La Roche AG Nucleoside-5 -oligophosphates having a cationically-modified nucleobase
WO2023277953A1 (en) * 2021-06-29 2023-01-05 Agilent Technologies, Inc. Polymerase mutants and use with 3'-oh unblocked reversible terminators
CN114250283B (zh) * 2021-10-15 2022-10-04 深圳铭毅智造科技有限公司 基于环境敏感染料的单色荧光mrt基因测序试剂及方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5302509A (en) * 1989-08-14 1994-04-12 Beckman Instruments, Inc. Method for sequencing polynucleotides
YU187991A (sh) * 1990-12-11 1994-09-09 Hoechst Aktiengesellschaft 3-(2)-amino-ali tiol-modifikovani, s fluorescentnom bojom vezani nukleozidi, nukleotidi i oligonukleotidi, postupak za njihovo dobijanje i njihova upotreba
US6211165B1 (en) * 1997-05-09 2001-04-03 The Trustees Of The University Of Pennsylvania Methods and compositions for reducing ischemic injury of the heart by administering adenosine receptor agonists and antagonists
US6586413B2 (en) * 1999-11-05 2003-07-01 The United States Of America As Represented By The Department Of Health And Human Services Methods and compositions for reducing ischemic injury of the heart by administering adenosine receptor agonists and antagonists
US6664079B2 (en) 2000-10-06 2003-12-16 The Trustees Of Columbia University In The City Of New York Massive parallel method for decoding DNA and RNA
NZ537939A (en) * 2001-04-10 2005-08-26 Ecole Polytech Methods using O6-alkylguanine-DNA alkyltransferases for labelling a protein of interest which is fused to the AGT
GB0128526D0 (en) * 2001-11-29 2002-01-23 Amersham Pharm Biotech Uk Ltd Nucleotide analogues
US7057026B2 (en) * 2001-12-04 2006-06-06 Solexa Limited Labelled nucleotides
ES2864086T3 (es) 2002-08-23 2021-10-13 Illumina Cambridge Ltd Nucleótidos etiquetados
CZ294538B6 (cs) * 2002-12-30 2005-01-12 Ústav Experimentální Botaniky Akademie Vědčeské Re Substituční deriváty N6-benzyladenosinu, způsob jejich přípravy, jejich použití pro přípravu léčiv, kosmetických přípravků a růstových regulátorů, farmaceutické přípravky, kosmetické přípravky a růstové regulátory tyto sloučeniny obsahující
CA2557818A1 (en) * 2004-03-03 2005-09-15 The Trustees Of Columbia University In The City Of New York Photocleavable fluorescent nucleotides for dna sequencing on chip constructed by site-specific coupling chemistry

Also Published As

Publication number Publication date
AU2007329361A1 (en) 2008-06-12
EP2125856A2 (en) 2009-12-02
EP2125856A4 (en) 2013-12-25
JP2011506265A (ja) 2011-03-03
EP2125856B1 (en) 2016-09-14
AU2007329361B2 (en) 2013-07-18
BRPI0719923B1 (pt) 2021-08-17
MX2009005936A (es) 2010-01-15
CA2670937A1 (en) 2008-06-12
CN102443030A (zh) 2012-05-09
WO2008070749A2 (en) 2008-06-12
CN102443030B (zh) 2015-12-16
RU2009121089A (ru) 2011-01-20
WO2008070749A3 (en) 2008-11-27
KR20090101451A (ko) 2009-09-28
MX338089B (es) 2016-04-01
HK1169413A1 (zh) 2013-01-25
NZ577303A (en) 2011-12-22
JP5513122B2 (ja) 2014-06-04
CA2670937C (en) 2016-07-26
IL199051A (en) 2013-11-28
KR101504640B1 (ko) 2015-03-20

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B25A Requested transfer of rights approved

Owner name: AGILENT TECHNOLOGIES INC. (US)

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07E Notice of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 05/12/2007, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO.