BRPI0720088A2 - Fluoresceína substancialmente pura - Google Patents

Fluoresceína substancialmente pura

Info

Publication number
BRPI0720088A2
BRPI0720088A2 BRPI0720088-9A2A BRPI0720088A BRPI0720088A2 BR PI0720088 A2 BRPI0720088 A2 BR PI0720088A2 BR PI0720088 A BRPI0720088 A BR PI0720088A BR PI0720088 A2 BRPI0720088 A2 BR PI0720088A2
Authority
BR
Brazil
Prior art keywords
substantially pure
pure fluorescein
fluorescein
pure
Prior art date
Application number
BRPI0720088-9A2A
Other languages
English (en)
Inventor
Gregory Bydlinski
Robert Gregg Harris
Britt S Scott
Original Assignee
Alcon Res Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39327263&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0720088(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alcon Res Ltd filed Critical Alcon Res Ltd
Publication of BRPI0720088A2 publication Critical patent/BRPI0720088A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • C07D311/82—Xanthenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
BRPI0720088-9A2A 2006-12-11 2007-12-04 Fluoresceína substancialmente pura BRPI0720088A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86948806P 2006-12-11 2006-12-11
PCT/US2007/086390 WO2008073764A2 (en) 2006-12-11 2007-12-04 Substantially pure fluorescein

Publications (1)

Publication Number Publication Date
BRPI0720088A2 true BRPI0720088A2 (pt) 2013-12-24

Family

ID=39327263

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0720088-9A2A BRPI0720088A2 (pt) 2006-12-11 2007-12-04 Fluoresceína substancialmente pura

Country Status (16)

Country Link
US (1) US7982056B2 (pt)
EP (2) EP2114953B1 (pt)
JP (2) JP5384363B2 (pt)
KR (2) KR20090086620A (pt)
CN (1) CN101605796B (pt)
AR (1) AR064288A1 (pt)
AU (1) AU2007333307B2 (pt)
BR (1) BRPI0720088A2 (pt)
CA (1) CA2671860C (pt)
CL (1) CL2007003593A1 (pt)
ES (1) ES2387925T3 (pt)
MX (1) MX2009005679A (pt)
RU (1) RU2477284C2 (pt)
TW (1) TWI518089B (pt)
WO (1) WO2008073764A2 (pt)
ZA (1) ZA200903447B (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2671860C (en) * 2006-12-11 2016-07-12 Alcon Research Ltd. Process for preparing substantially pure fluorescein
CN107660207B (zh) 2015-03-10 2020-09-29 罗德科技公司 丁丙诺啡乙酸盐及用于制备丁丙诺啡的方法
WO2017082430A1 (ja) * 2015-11-12 2017-05-18 参天製薬株式会社 高純度フルオレセインナトリウム
US10293047B1 (en) 2017-11-15 2019-05-21 Paragon BioTeck, Inc. Fluorescein and benoxinate compositions
US12210224B2 (en) * 2018-11-29 2025-01-28 Neena Singhal James Ophthalmic solutions having visual marker for safer contact lens insertion and removal
CN113461651A (zh) * 2021-08-20 2021-10-01 山东绅联药业有限公司 一种高纯度荧光素的纯化方法
WO2023037158A1 (en) * 2021-09-09 2023-03-16 Macsen Drugs Process for preparation of crystalline fluorescein sodium from diacetylfluorescein or fluorescein
CN116023389A (zh) * 2021-10-25 2023-04-28 英格尔医药科技(上海)有限公司 荧光素钠的晶型a、其制备方法及其用途
EP4489796A1 (en) * 2022-03-07 2025-01-15 Opus Life Sciences, Llc Fluorescein formulations and kits
CN117285500B (zh) * 2022-06-17 2025-10-17 广西梧州制药(集团)股份有限公司 一种高纯度荧光素钠的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1965842A (en) 1931-11-21 1934-07-10 Nat Aniline & Chem Co Inc Production of hydroxybenzenephthaleins
DD136498A1 (de) * 1978-05-11 1979-07-11 Friedmut Friedrich Verfahren zur herstellung von hochgereinigtem fluorescein fuer injektionszwecke
US5188934A (en) * 1989-11-14 1993-02-23 Applied Biosystems, Inc. 4,7-dichlorofluorescein dyes as molecular probes
US5637733A (en) 1995-09-27 1997-06-10 Warner-Jenkinson Company, Inc. Syntheses of fluorescein compounds with excess resorcinol as a solvent
US6162931A (en) * 1996-04-12 2000-12-19 Molecular Probes, Inc. Fluorinated xanthene derivatives
DE19923168A1 (de) * 1999-05-20 2000-11-23 Roche Diagnostics Gmbh Neue Fluoreszenzfarbstoffe und ihre Verwendung als Fluoreszenzmarker
FR2846331B1 (fr) * 2002-10-29 2006-11-17 Synth Innove Lab Phtaleines de purete elevee et leur procede de preparation
RU2287007C1 (ru) * 2005-07-28 2006-11-10 Борис Маркович Болотин Бесцветные, растворимые в воде органические люминофоры
CA2671860C (en) * 2006-12-11 2016-07-12 Alcon Research Ltd. Process for preparing substantially pure fluorescein

Also Published As

Publication number Publication date
CN101605796A (zh) 2009-12-16
KR20150013356A (ko) 2015-02-04
JP2013241472A (ja) 2013-12-05
AR064288A1 (es) 2009-03-25
TWI518089B (zh) 2016-01-21
ES2387925T3 (es) 2012-10-04
CA2671860C (en) 2016-07-12
CL2007003593A1 (es) 2008-08-22
RU2477284C2 (ru) 2013-03-10
RU2009126572A (ru) 2011-01-20
US7982056B2 (en) 2011-07-19
JP2010512409A (ja) 2010-04-22
CN101605796B (zh) 2012-10-03
ZA200903447B (en) 2010-08-25
EP2481741A1 (en) 2012-08-01
KR20090086620A (ko) 2009-08-13
EP2114953A2 (en) 2009-11-11
WO2008073764A3 (en) 2009-07-30
TW200838864A (en) 2008-10-01
CA2671860A1 (en) 2008-06-19
MX2009005679A (es) 2009-06-08
US20080176930A1 (en) 2008-07-24
EP2114953B1 (en) 2012-06-06
HK1134288A1 (en) 2010-04-23
AU2007333307A1 (en) 2008-06-19
JP5384363B2 (ja) 2014-01-08
KR101571409B1 (ko) 2015-11-24
AU2007333307B2 (en) 2013-05-23
WO2008073764A2 (en) 2008-06-19

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL