BRPI0720089A2 - Uso de l-carnitina para a preparação de um medicamento na forma de colírio para o tratamento de doenças da córnea - Google Patents

Uso de l-carnitina para a preparação de um medicamento na forma de colírio para o tratamento de doenças da córnea

Info

Publication number
BRPI0720089A2
BRPI0720089A2 BRPI0720089-7A2A BRPI0720089A BRPI0720089A2 BR PI0720089 A2 BRPI0720089 A2 BR PI0720089A2 BR PI0720089 A BRPI0720089 A BR PI0720089A BR PI0720089 A2 BRPI0720089 A2 BR PI0720089A2
Authority
BR
Brazil
Prior art keywords
eyewear
carnitine
drug
preparation
treatment
Prior art date
Application number
BRPI0720089-7A2A
Other languages
English (en)
Inventor
Aleardo Koverech
Nicola Pescosolido
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Publication of BRPI0720089A2 publication Critical patent/BRPI0720089A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BRPI0720089-7A2A 2006-12-11 2007-11-21 Uso de l-carnitina para a preparação de um medicamento na forma de colírio para o tratamento de doenças da córnea BRPI0720089A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06125770 2006-12-11
PCT/EP2007/062610 WO2008071524A1 (en) 2006-12-11 2007-11-21 Use of l-carnitine for the preparation of a medicament in the form of eye-drops for treating corneal diseases

Publications (1)

Publication Number Publication Date
BRPI0720089A2 true BRPI0720089A2 (pt) 2013-12-24

Family

ID=37603705

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0720089-7A2A BRPI0720089A2 (pt) 2006-12-11 2007-11-21 Uso de l-carnitina para a preparação de um medicamento na forma de colírio para o tratamento de doenças da córnea

Country Status (12)

Country Link
US (1) US8158679B2 (pt)
EP (1) EP2091529A1 (pt)
JP (1) JP5384362B2 (pt)
KR (1) KR101447601B1 (pt)
CN (1) CN101534812B (pt)
AU (1) AU2007332680B2 (pt)
BR (1) BRPI0720089A2 (pt)
CA (1) CA2667069C (pt)
EA (1) EA017752B1 (pt)
MX (1) MX2009005503A (pt)
SG (1) SG176481A1 (pt)
WO (1) WO2008071524A1 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8389014B2 (en) * 2006-12-22 2013-03-05 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Gel useful for the delivery of ophthalmic drugs
TW201322982A (zh) * 2011-11-01 2013-06-16 Otsuka Pharma Co Ltd 用於治療前眼疾病之藥劑，該藥劑包含瑞巴派特及眼淚保持劑
EP2783695A1 (en) * 2013-03-28 2014-10-01 SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. Physiological supplement or medicament for ophthalmic use containing L-carnitine or alkanoyl L-carnitines in combination with eledoisin
FR3019465B1 (fr) 2014-04-02 2017-06-23 Horus Pharma Composition hyperosmolaire d'acide hyaluronique et son utilisation pour le traitement de l'oedeme corneen
EP4419145A4 (en) * 2021-10-19 2025-03-12 VSY Biyoteknoloji Ve Ilac Sanayi Anonim Sirketi OPHTHALMIC FORMULATIONS FOR THE TREATMENT OF PRESBYTERIA, DRY EYE AND COMPUTER VISION SYNDROME

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08133968A (ja) * 1994-09-14 1996-05-28 Taisho Pharmaceut Co Ltd 角膜障害修復用点眼液
WO2000029030A1 (en) * 1998-11-13 2000-05-25 Continental Projects Limited Complexes of hyaluronic acid/carnitines and pharmaceutical and cosmetic compositions
RU2165749C1 (ru) * 2000-07-06 2001-04-27 Общество с ограниченной ответственностью "Научно-экспериментальное производство Микрохирургия глаза" Способ восстановления эндотелия роговицы
US7465463B2 (en) * 2002-09-04 2008-12-16 Polyheal, Ltd. Compositions comprising microspheres with anti-inflammatory properties for healing of ocular tissues
EP1793836A4 (en) * 2004-10-01 2008-09-03 Richard L Lindstrom OPHTHALMIC COMPOSITIONS WITH LUBRICANTS, DETERMINANTS AND GLYCOSAMINOGLYCAN AND METHOD FOR THEIR USE
US8569367B2 (en) 2004-11-16 2013-10-29 Allergan, Inc. Ophthalmic compositions and methods for treating eyes
AU2006265248B2 (en) * 2005-07-01 2011-12-15 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Use of L-carnitine or of alkanoyl L-carnitines for the preparation of a physiological supplement or medicament for ophthalmic use in the form of eye-drops

Also Published As

Publication number Publication date
JP2010512363A (ja) 2010-04-22
CN101534812B (zh) 2012-09-05
KR20090087453A (ko) 2009-08-17
EA017752B1 (ru) 2013-02-28
WO2008071524A1 (en) 2008-06-19
US8158679B2 (en) 2012-04-17
MX2009005503A (es) 2009-06-04
EP2091529A1 (en) 2009-08-26
AU2007332680B2 (en) 2013-02-07
SG176481A1 (en) 2011-12-29
CA2667069C (en) 2015-05-26
KR101447601B1 (ko) 2014-10-07
CA2667069A1 (en) 2008-06-19
HK1135019A1 (en) 2010-05-28
JP5384362B2 (ja) 2014-01-08
EA200970562A1 (ru) 2009-10-30
AU2007332680A1 (en) 2008-06-19
US20100068300A1 (en) 2010-03-18
CN101534812A (zh) 2009-09-16

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 9A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2386 DE 27-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.