BRPI0806365B8 - composto, uso do composto, composição farmacêutica e uso da composição farmacêutica - Google Patents

composto, uso do composto, composição farmacêutica e uso da composição farmacêutica

Info

Publication number
BRPI0806365B8
BRPI0806365B8 BRPI0806365A BRPI0806365A BRPI0806365B8 BR PI0806365 B8 BRPI0806365 B8 BR PI0806365B8 BR PI0806365 A BRPI0806365 A BR PI0806365A BR PI0806365 A BRPI0806365 A BR PI0806365A BR PI0806365 B8 BRPI0806365 B8 BR PI0806365B8
Authority
BR
Brazil
Prior art keywords
compound
pharmaceutical composition
tumors
preparing
treatment
Prior art date
Application number
BRPI0806365A
Other languages
English (en)
Inventor
Johnson Francis
S Kovach John
Original Assignee
Lixte Biotechnology Holdings Inc
Lixte Biotechnology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lixte Biotechnology Holdings Inc, Lixte Biotechnology Inc filed Critical Lixte Biotechnology Holdings Inc
Publication of BRPI0806365A2 publication Critical patent/BRPI0806365A2/pt
Publication of BRPI0806365B1 publication Critical patent/BRPI0806365B1/pt
Publication of BRPI0806365B8 publication Critical patent/BRPI0806365B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
    • A01N47/16—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof the nitrogen atom being part of a heterocyclic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/203—Retinoic acids ; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

composto, composição farmacêutica, processo de preparação de um composto, método de controle de vegetação indesejada, método de inibição da atividade de fosfatase vegetal, uso do composto. a presente invenção fornece compostos que possuem a estrutura que pode ser utilizada para o tratamento de tumores.
BRPI0806365A 2007-02-06 2008-02-06 composto, uso do composto, composição farmacêutica e uso da composição farmacêutica BRPI0806365B8 (pt)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US89990307P 2007-02-06 2007-02-06
US60/899,903 2007-02-06
US96490407P 2007-08-14 2007-08-14
US60/964,904 2007-08-14
US1132308P 2008-01-15 2008-01-15
US61/011,323 2008-01-15
PCT/US2008/001549 WO2008097561A1 (en) 2007-02-06 2008-02-06 Oxabicycloheptanes and oxabicycloheptenes, their preparation and use

Publications (3)

Publication Number Publication Date
BRPI0806365A2 BRPI0806365A2 (pt) 2011-09-06
BRPI0806365B1 BRPI0806365B1 (pt) 2020-01-21
BRPI0806365B8 true BRPI0806365B8 (pt) 2021-05-25

Family

ID=39682021

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0806365A BRPI0806365B8 (pt) 2007-02-06 2008-02-06 composto, uso do composto, composição farmacêutica e uso da composição farmacêutica

Country Status (10)

Country Link
US (6) US7998957B2 (pt)
EP (1) EP2124550B1 (pt)
JP (1) JP5693850B2 (pt)
CN (2) CN103788108B (pt)
AU (1) AU2008214299B2 (pt)
BR (1) BRPI0806365B8 (pt)
CA (1) CA2676422C (pt)
EA (1) EA023804B1 (pt)
MX (1) MX2009008347A (pt)
WO (1) WO2008097561A1 (pt)

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US8227473B2 (en) * 2008-08-01 2012-07-24 Lixte Biotechnology, Inc. Oxabicycloheptanes and oxabicycloheptenes, their preparation and use
JP6262225B2 (ja) 2012-06-29 2018-01-17 リクスト・バイオテクノロジー，インコーポレイテッド オキサビシクロヘプタン類、および再灌流障害の治療のためのオキサビシクロヘプタン類
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EP2983661B1 (en) * 2013-04-09 2024-05-29 Lixte Biotechnology, Inc. Formulations of oxabicycloheptanes and oxabicycloheptenes
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EP2124550B1 (en) 2017-04-19
CN103788108A (zh) 2014-05-14
WO2008097561A8 (en) 2009-10-01
CA2676422C (en) 2018-10-16
US20120270736A1 (en) 2012-10-25
AU2008214299B2 (en) 2014-01-09
US20180370983A1 (en) 2018-12-27
JP5693850B2 (ja) 2015-04-01
CA2676422A1 (en) 2008-08-14
EA023804B1 (ru) 2016-07-29
MX2009008347A (es) 2009-10-19
CN103788108B (zh) 2017-04-12
US7998957B2 (en) 2011-08-16
AU2008214299A1 (en) 2008-08-14
US20170369503A1 (en) 2017-12-28
WO2008097561A1 (en) 2008-08-14
EA200970737A1 (ru) 2010-02-26
EP2124550A1 (en) 2009-12-02
BRPI0806365B1 (pt) 2020-01-21
US9079917B2 (en) 2015-07-14
CN101662939B (zh) 2015-11-25
US20150045373A1 (en) 2015-02-12
US8822461B2 (en) 2014-09-02
US20090036309A1 (en) 2009-02-05
BRPI0806365A2 (pt) 2011-09-06
US8426444B2 (en) 2013-04-23
US10023587B2 (en) 2018-07-17
CN101662939A (zh) 2010-03-03
US20130302402A1 (en) 2013-11-14
US10399993B2 (en) 2019-09-03
JP2010518081A (ja) 2010-05-27

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