BRPI0807681A2 - ensaios baseados em gotícula de peróxido de hidrogênio - Google Patents

ensaios baseados em gotícula de peróxido de hidrogênio

Info

Publication number
BRPI0807681A2
BRPI0807681A2 BRPI0807681A BRPI0807681A BRPI0807681A2 BR PI0807681 A2 BRPI0807681 A2 BR PI0807681A2 BR PI0807681 A BRPI0807681 A BR PI0807681A BR PI0807681 A BRPI0807681 A BR PI0807681A BR PI0807681 A2 BRPI0807681 A2 BR PI0807681A2
Authority
BR
Brazil
Prior art keywords
hydrogen peroxide
based assays
peroxide droplet
droplet
assays
Prior art date
Application number
BRPI0807681A
Other languages
English (en)
Inventor
E Eckhardt Allen
Original Assignee
Advanced Liquid Logic Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Advanced Liquid Logic Inc filed Critical Advanced Liquid Logic Inc
Publication of BRPI0807681A2 publication Critical patent/BRPI0807681A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/28—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/005—Enzyme electrodes involving specific analytes or enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/005—Enzyme electrodes involving specific analytes or enzymes
    • C12Q1/006—Enzyme electrodes involving specific analytes or enzymes for glucose
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/902—Oxidoreductases (1.)
    • G01N2333/904—Oxidoreductases (1.) acting on CHOH groups as donors, e.g. glucose oxidase, lactate dehydrogenase (1.1)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/11—Automated chemical analysis
    • Y10T436/117497—Automated chemical analysis with a continuously flowing sample or carrier stream
    • Y10T436/118339—Automated chemical analysis with a continuously flowing sample or carrier stream with formation of a segmented stream
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/141111—Diverse hetero atoms in same or different rings [e.g., alkaloids, opiates, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]
    • Y10T436/144444—Glucose
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/145555—Hetero-N
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/145555—Hetero-N
    • Y10T436/146666—Bile pigment
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/145555—Hetero-N
    • Y10T436/147777—Plural nitrogen in the same ring [e.g., barbituates, creatinine, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/145555—Hetero-N
    • Y10T436/147777—Plural nitrogen in the same ring [e.g., barbituates, creatinine, etc.]
    • Y10T436/148888—Uric acid
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/20—Oxygen containing
    • Y10T436/206664—Ozone or peroxide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Emergency Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
BRPI0807681A 2007-03-05 2008-03-05 ensaios baseados em gotícula de peróxido de hidrogênio BRPI0807681A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US89297107P 2007-03-05 2007-03-05
US98018607P 2007-10-16 2007-10-16
PCT/US2008/055891 WO2008109664A1 (en) 2007-03-05 2008-03-05 Hydrogen peroxide droplet-based assays

Publications (1)

Publication Number Publication Date
BRPI0807681A2 true BRPI0807681A2 (pt) 2018-10-30

Family

ID=39738768

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0807681A BRPI0807681A2 (pt) 2007-03-05 2008-03-05 ensaios baseados em gotícula de peróxido de hidrogênio

Country Status (9)

Country Link
US (1) US8426213B2 (pt)
EP (1) EP2118303B1 (pt)
JP (1) JP5491203B2 (pt)
KR (1) KR101523754B1 (pt)
CN (1) CN101663403B (pt)
AU (1) AU2008222860B2 (pt)
BR (1) BRPI0807681A2 (pt)
CA (1) CA2716603A1 (pt)
WO (1) WO2008109664A1 (pt)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2594483C (en) 2005-01-28 2014-08-26 Duke University Apparatuses and methods for manipulating droplets on a printed circuit board
US20140193807A1 (en) 2006-04-18 2014-07-10 Advanced Liquid Logic, Inc. Bead manipulation techniques
US8716015B2 (en) 2006-04-18 2014-05-06 Advanced Liquid Logic, Inc. Manipulation of cells on a droplet actuator
US8809068B2 (en) 2006-04-18 2014-08-19 Advanced Liquid Logic, Inc. Manipulation of beads in droplets and methods for manipulating droplets
US10078078B2 (en) 2006-04-18 2018-09-18 Advanced Liquid Logic, Inc. Bead incubation and washing on a droplet actuator
US8658111B2 (en) * 2006-04-18 2014-02-25 Advanced Liquid Logic, Inc. Droplet actuators, modified fluids and methods
US7439014B2 (en) 2006-04-18 2008-10-21 Advanced Liquid Logic, Inc. Droplet-based surface modification and washing
US8637324B2 (en) 2006-04-18 2014-01-28 Advanced Liquid Logic, Inc. Bead incubation and washing on a droplet actuator
WO2009111769A2 (en) 2008-03-07 2009-09-11 Advanced Liquid Logic, Inc. Reagent and sample preparation and loading on a fluidic device
US8685344B2 (en) 2007-01-22 2014-04-01 Advanced Liquid Logic, Inc. Surface assisted fluid loading and droplet dispensing
EP2570811B1 (en) 2007-02-09 2014-11-26 Advanced Liquid Logic, Inc. Droplet actuator devices and methods employing magnetic beads
US8872527B2 (en) 2007-02-15 2014-10-28 Advanced Liquid Logic, Inc. Capacitance detection in a droplet actuator
EP2837692A1 (en) 2007-03-22 2015-02-18 Advanced Liquid Logic, Inc. Enzymatic assays for a droplet actuator
WO2011084703A2 (en) 2009-12-21 2011-07-14 Advanced Liquid Logic, Inc. Enzyme assays on a droplet actuator
CN101743304B (zh) * 2007-04-10 2013-04-24 先进流体逻辑公司 微滴分配设备和方法
WO2009002920A1 (en) 2007-06-22 2008-12-31 Advanced Liquid Logic, Inc. Droplet-based nucleic acid amplification in a temperature gradient
WO2009032863A2 (en) 2007-09-04 2009-03-12 Advanced Liquid Logic, Inc. Droplet actuator with improved top substrate
US20100236928A1 (en) * 2007-10-17 2010-09-23 Advanced Liquid Logic, Inc. Multiplexed Detection Schemes for a Droplet Actuator
WO2009052321A2 (en) * 2007-10-18 2009-04-23 Advanced Liquid Logic, Inc. Droplet actuators, systems and methods
AU2008345138B2 (en) 2007-12-23 2014-05-29 Advanced Liquid Logic, Inc. Droplet actuator configurations and methods of conducting droplet operations
US8852952B2 (en) 2008-05-03 2014-10-07 Advanced Liquid Logic, Inc. Method of loading a droplet actuator
EP2286228B1 (en) * 2008-05-16 2019-04-03 Advanced Liquid Logic, Inc. Droplet actuator devices and methods for manipulating beads
US8877512B2 (en) * 2009-01-23 2014-11-04 Advanced Liquid Logic, Inc. Bubble formation techniques using physical or chemical features to retain a gas bubble within a droplet actuator
US8926065B2 (en) 2009-08-14 2015-01-06 Advanced Liquid Logic, Inc. Droplet actuator devices and methods
US9091649B2 (en) 2009-11-06 2015-07-28 Advanced Liquid Logic, Inc. Integrated droplet actuator for gel; electrophoresis and molecular analysis
US9248450B2 (en) 2010-03-30 2016-02-02 Advanced Liquid Logic, Inc. Droplet operations platform
US10232374B2 (en) 2010-05-05 2019-03-19 Miroculus Inc. Method of processing dried samples using digital microfluidic device
EP2588322B1 (en) 2010-06-30 2015-06-17 Advanced Liquid Logic, Inc. Droplet actuator assemblies and methods of making same
EP2707131B1 (en) 2011-05-09 2019-04-24 Advanced Liquid Logic, Inc. Microfluidic feedback using impedance detection
US9140635B2 (en) 2011-05-10 2015-09-22 Advanced Liquid Logic, Inc. Assay for measuring enzymatic modification of a substrate by a glycoprotein having enzymatic activity
JP5894272B2 (ja) 2011-07-06 2016-03-23 アドバンスト リキッド ロジック インコーポレイテッドAdvanced Liquid Logic, Inc. 液滴アクチュエーターにおける試薬保存
US8901043B2 (en) 2011-07-06 2014-12-02 Advanced Liquid Logic, Inc. Systems for and methods of hybrid pyrosequencing
WO2013009927A2 (en) 2011-07-11 2013-01-17 Advanced Liquid Logic, Inc. Droplet actuators and techniques for droplet-based assays
WO2013016413A2 (en) 2011-07-25 2013-01-31 Advanced Liquid Logic Inc Droplet actuator apparatus and system
AU2012336040B2 (en) 2011-11-07 2015-12-10 Illumina, Inc. Integrated sequencing apparatuses and methods of use
WO2013078216A1 (en) 2011-11-21 2013-05-30 Advanced Liquid Logic Inc Glucose-6-phosphate dehydrogenase assays
JP2013236559A (ja) 2012-05-11 2013-11-28 Sharp Corp 反応検出方法
US9223317B2 (en) 2012-06-14 2015-12-29 Advanced Liquid Logic, Inc. Droplet actuators that include molecular barrier coatings
EP2867645B1 (en) 2012-06-27 2019-06-05 Advanced Liquid Logic, Inc. Techniques and droplet actuator designs for reducing bubble formation
WO2014062551A1 (en) 2012-10-15 2014-04-24 Advanced Liquid Logic, Inc. Digital microfluidics cartridge and system for operating a flow cell
US20140322706A1 (en) 2012-10-24 2014-10-30 Jon Faiz Kayyem Integrated multipelx target analysis
US9957553B2 (en) 2012-10-24 2018-05-01 Genmark Diagnostics, Inc. Integrated multiplex target analysis
CN107866286A (zh) 2013-03-15 2018-04-03 金马克诊断股份有限公司 用于操纵可变形流体容器的系统、方法和设备
US9915670B2 (en) 2013-09-16 2018-03-13 Nanyang Technological University Method of detecting hydrogen peroxide
US9498778B2 (en) 2014-11-11 2016-11-22 Genmark Diagnostics, Inc. Instrument for processing cartridge for performing assays in a closed sample preparation and reaction system
USD881409S1 (en) 2013-10-24 2020-04-14 Genmark Diagnostics, Inc. Biochip cartridge
US9598722B2 (en) 2014-11-11 2017-03-21 Genmark Diagnostics, Inc. Cartridge for performing assays in a closed sample preparation and reaction system
US10005080B2 (en) 2014-11-11 2018-06-26 Genmark Diagnostics, Inc. Instrument and cartridge for performing assays in a closed sample preparation and reaction system employing electrowetting fluid manipulation
AU2015346527A1 (en) 2014-11-11 2017-06-29 Genmark Diagnostics, Inc. Instrument and cartridge for performing assays in a closed sample preparation and reaction system
CN108026494A (zh) 2015-06-05 2018-05-11 米罗库鲁斯公司 限制蒸发和表面结垢的空气基质数字微流控装置和方法
US10695762B2 (en) 2015-06-05 2020-06-30 Miroculus Inc. Evaporation management in digital microfluidic devices
WO2018039281A1 (en) 2016-08-22 2018-03-01 Miroculus Inc. Feedback system for parallel droplet control in a digital microfluidic device
EP3516401B1 (en) 2016-09-19 2025-07-30 Roche Diagnostics GmbH Instrument for processing cartridge for performing assays in a closed sample preparation and reaction system
WO2018126082A1 (en) 2016-12-28 2018-07-05 Miroculis Inc. Digital microfluidic devices and methods
US11623219B2 (en) 2017-04-04 2023-04-11 Miroculus Inc. Digital microfluidics apparatuses and methods for manipulating and processing encapsulated droplets
EP3658908B1 (en) 2017-07-24 2025-11-12 Integra Biosciences AG Digital microfluidics systems and methods with integrated plasma collection device
WO2019046860A1 (en) 2017-09-01 2019-03-07 Miroculus Inc. DIGITAL MICROFLUIDIC DEVICES AND METHODS OF USE
CA3096855A1 (en) 2018-05-23 2019-11-28 Miroculus Inc. Control of evaporation in digital microfluidics
US12233390B2 (en) 2019-01-31 2025-02-25 Miroculus Inc. Nonfouling compositions and methods for manipulating and processing encapsulated droplets
WO2020176816A1 (en) 2019-02-28 2020-09-03 Miroculus Inc. Digital microfluidics devices and methods of using them
WO2020210292A1 (en) 2019-04-08 2020-10-15 Miroculus Inc. Multi-cartridge digital microfluidics apparatuses and methods of use
US11524298B2 (en) 2019-07-25 2022-12-13 Miroculus Inc. Digital microfluidics devices and methods of use thereof
WO2021252923A1 (en) 2020-06-12 2021-12-16 Genmark Diagnostics, Inc. Systems and methods for assessing bays on diagnostic devices
US11857961B2 (en) 2022-01-12 2024-01-02 Miroculus Inc. Sequencing by synthesis using mechanical compression

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1598153C3 (de) * 1966-11-22 1973-11-22 Boehringer Mannheim Gmbh, 6800 Mannheim Diagnostisches Mittel zum Nach weis der Inhaltsstoffe von Korperflus sigkeiten
JPS5425892A (en) * 1977-07-29 1979-02-27 Wako Pure Chem Ind Ltd Quantitative determination of hydrogen peroxide
US4260392A (en) * 1978-07-07 1981-04-07 Technicon Instruments Corporation Method and apparatus for obtaining an aliquot of a liquid in a gel medium
JPS5520471A (en) * 1978-08-01 1980-02-13 Kyowa Hakko Kogyo Co Ltd Hydrogen peroxide quantifying method
JPS5823079B2 (ja) * 1978-11-15 1983-05-12 バテル メモリアル インステイチユ−ト 水性媒質中の過酸化水素の量および酵素酸化によって過酸化水素を発生する有機基質の量を測定する分析方法および手段
US4247297A (en) * 1979-02-23 1981-01-27 Miles Laboratories, Inc. Test means and method for interference resistant determination of oxidizing substances
US4269938A (en) * 1979-03-08 1981-05-26 Eastman Kodak Company Assay of peroxidatively active materials
US4336330A (en) * 1980-12-15 1982-06-22 Miles Laboratories, Inc. Device for detecting glucose concentration
US4397956A (en) * 1981-12-10 1983-08-09 Maggio Edward T Means for monitoring the status of control of ketoacidosis-prone diabetics
JPS58149677A (ja) * 1982-03-02 1983-09-06 Toyo Jozo Co Ltd L−グルタミン酸オキシダ−ゼ(h↓2o↓2・ジエネレイテイング)およびその製造法、ならびに分析方法
US4778893A (en) * 1983-03-14 1988-10-18 Miles Inc. Optical indicator 3,4-dihydro-2-quinolones
US4659677A (en) * 1983-05-26 1987-04-21 Eastman Kodak Company Method providing liquid mixing outside containers
JPS60108753A (ja) * 1983-11-18 1985-06-14 Fuji Photo Film Co Ltd 多層化学分析要素
US4649121A (en) * 1985-02-26 1987-03-10 Miles Laboratories, Inc. Viability test device
DE3608453A1 (de) * 1986-03-14 1987-09-17 Boehringer Mannheim Gmbh Verfahren zur enzymatischen bestimmung von bilirubin im serum
DE3619436A1 (de) * 1986-06-10 1987-12-17 Bayer Ag Triaryl- und trihetarylmethanderivate als redoxindikatoren und deren verwendung
JP2528457B2 (ja) * 1987-03-09 1996-08-28 サントリー株式会社 過酸化水素の定量法
US4894472A (en) * 1988-03-21 1990-01-16 Miles Inc. Dicyanoethylaryl derivatives and process for their preparation
DE3826922A1 (de) * 1988-08-09 1990-02-22 Boehringer Mannheim Gmbh Verfahren zur kolorimetrischen bestimmung eines analyten mittels enzymatischer oxidation
US5110724A (en) * 1990-04-02 1992-05-05 Cholestech Corporation Multi-analyte assay device
JP3342077B2 (ja) * 1992-02-03 2002-11-05 ライフスキヤン・インコーポレーテツド 分析物の分光光度定量分析のための改良酸化カツプリング染料
US5603351A (en) * 1995-06-07 1997-02-18 David Sarnoff Research Center, Inc. Method and system for inhibiting cross-contamination in fluids of combinatorial chemistry device
US5879632A (en) * 1996-04-09 1999-03-09 Sarnoff Corporation Apportioning system
US6162397A (en) * 1998-08-13 2000-12-19 Lifescan, Inc. Visual blood glucose test strip
US6565727B1 (en) * 1999-01-25 2003-05-20 Nanolytics, Inc. Actuators for microfluidics without moving parts
US6294063B1 (en) * 1999-02-12 2001-09-25 Board Of Regents, The University Of Texas System Method and apparatus for programmable fluidic processing
US6251083B1 (en) * 1999-09-07 2001-06-26 Amira Medical Interstitial fluid methods and devices for determination of an analyte in the body
AU2001268536A1 (en) * 2000-06-14 2001-12-24 Board Of Regents, The University Of Texas System Apparatus and method for fluid injection
US7294503B2 (en) * 2000-09-15 2007-11-13 California Institute Of Technology Microfabricated crossflow devices and methods
US6866762B2 (en) * 2001-12-20 2005-03-15 Board Of Regents, University Of Texas System Dielectric gate and methods for fluid injection and control
JP2005515058A (ja) * 2002-01-04 2005-05-26 ボード・オブ・リージエンツ,ザ・ユニバーシテイ・オブ・テキサス・システム 流体の経路割当および制限のための無壁チャネル
EP1508044B1 (en) * 2002-05-09 2010-09-01 The University of Chicago Device and method for pressure-driven plug transport and reaction
US7329545B2 (en) * 2002-09-24 2008-02-12 Duke University Methods for sampling a liquid flow
US20050038329A1 (en) * 2002-11-20 2005-02-17 Morris Carol Ann Methods and kits for assays of rapid screening of diabetes
CA2479452C (en) * 2003-08-30 2008-11-04 F.Hoffmann-La Roche Ag Method and device for determining analytes in a liquid
WO2006085905A1 (en) * 2004-05-28 2006-08-17 Board Of Regents, The University Of Texas System Programmable fluidic processors
CA2594483C (en) * 2005-01-28 2014-08-26 Duke University Apparatuses and methods for manipulating droplets on a printed circuit board
JP4547301B2 (ja) * 2005-05-13 2010-09-22 株式会社日立ハイテクノロジーズ 液体搬送デバイス及び分析システム

Also Published As

Publication number Publication date
US8426213B2 (en) 2013-04-23
EP2118303A1 (en) 2009-11-18
WO2008109664A1 (en) 2008-09-12
JP5491203B2 (ja) 2014-05-14
US20100028920A1 (en) 2010-02-04
KR101523754B1 (ko) 2015-05-28
AU2008222860B2 (en) 2013-10-31
JP2010519935A (ja) 2010-06-10
CN101663403B (zh) 2013-04-24
KR20100014670A (ko) 2010-02-10
CA2716603A1 (en) 2009-09-12
AU2008222860A1 (en) 2008-09-12
CN101663403A (zh) 2010-03-03
EP2118303B1 (en) 2014-11-19
EP2118303A4 (en) 2010-05-05

Similar Documents

Publication Publication Date Title
EP2118303A4 (en) ASSAYS BASED ON HYDROGEN PEROXIDE POTS
EP2140134A4 (en) WAVE POWER PLANT
NO2015017I1 (no) Apremilast
BRPI0818380A2 (pt) Combinação de herbicida-protetor
BRPI0820349A2 (pt) Adesivos em dispersão ii
BRPI0815557A2 (pt) Atividaores de glicocinase
BRPI0813843A2 (pt) Contactor
BRPI0807137A2 (pt) Agentes antiparasitários
EP2044055A4 (en) amide compounds
DE112008002590A5 (de) Mikroreaktor
DK2225175T3 (da) Stabiliserede hydrogenperoxidopløsninger
FR2913269B1 (fr) Telemetre multicolore
EP2200926A4 (en) MODIFIED HANDRAIL
BRPI0814572A2 (pt) Célula de lítio
DE602007006006D1 (de) Schutzschalteranordnung
DE602008000912D1 (de) Schaltanlage
EP2274314A4 (en) PEROXIDE ACTIVATORS WITH METALLOCARBENE COMPLEX
BRPI0813726A2 (pt) Célula de lítio
BRPI0914495A2 (pt) forno de decomposição de etileno
BRPI0918173A2 (pt) estrutura em degraus
BRPI0909909A2 (pt) caderno de composição
BRPI0922175A2 (pt) dispersões de peróxido
DE602007013035D1 (de) Schutzschalter
DE112008001259A5 (de) Dosiermagnet
BRPI0822681A2 (pt) máquina de escrever em braille

Legal Events

Date Code Title Description
B08F Application fees: application dismissed [chapter 8.6 patent gazette]

Free format text: REFERENTE A 11A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2504 DE 02-01-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.