BRPI0807732B8 - composição em gel, processo para fabricação da composição e uso de uma composição - Google Patents
composição em gel, processo para fabricação da composição e uso de uma composiçãoInfo
- Publication number
- BRPI0807732B8 BRPI0807732B8 BRPI0807732A BRPI0807732A BRPI0807732B8 BR PI0807732 B8 BRPI0807732 B8 BR PI0807732B8 BR PI0807732 A BRPI0807732 A BR PI0807732A BR PI0807732 A BRPI0807732 A BR PI0807732A BR PI0807732 B8 BRPI0807732 B8 BR PI0807732B8
- Authority
- BR
- Brazil
- Prior art keywords
- composition
- gel
- making
- prophylaxis
- epistaxis
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/765—Polymers containing oxygen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/14—Alkali metal chlorides; Alkaline earth metal chlorides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Otolaryngology (AREA)
- Inorganic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
composição em gel, processo para fabricação da composição, método de tratamento de epistaxe por profilaxia ou terapia, composição seca, uso de uma composição, e, processo para a preparação de uma composição em gel. a invenção refere-se a uma composição em gel que compreende: a) um polímero de carbóxi polimetileno; b) glicina; c) uma fonte de íons de cálcio e d) água. a invenção também se estende a uma composição seca que compreende os componentes a), b) e c) mencionadas antes. as composições em gel da invenção são úteis para a profilaxia e para o tratamento de epistaxe. as composições em gel podem ser facilmente administrativo á cavidade nasal e não requerem remoção depois uso.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0703377A GB2447012B (en) | 2007-02-21 | 2007-02-21 | Composition for combating epistaxis |
| GB0703377.2 | 2007-02-21 | ||
| PCT/GB2008/000608 WO2008102150A2 (en) | 2007-02-21 | 2008-02-21 | Composition for combating epistaxis |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BRPI0807732A2 BRPI0807732A2 (pt) | 2014-06-03 |
| BRPI0807732B1 BRPI0807732B1 (pt) | 2020-08-04 |
| BRPI0807732B8 true BRPI0807732B8 (pt) | 2021-05-25 |
Family
ID=37909023
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0807732A BRPI0807732B8 (pt) | 2007-02-21 | 2008-02-21 | composição em gel, processo para fabricação da composição e uso de uma composição |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US9138406B2 (pt) |
| EP (1) | EP2117502B1 (pt) |
| JP (1) | JP2010519285A (pt) |
| KR (1) | KR20090130001A (pt) |
| CN (1) | CN101677940B (pt) |
| AU (1) | AU2008217608B2 (pt) |
| BR (1) | BRPI0807732B8 (pt) |
| CA (1) | CA2678706C (pt) |
| DK (1) | DK2117502T3 (pt) |
| ES (1) | ES2606947T3 (pt) |
| GB (1) | GB2447012B (pt) |
| HR (1) | HRP20161626T1 (pt) |
| HU (1) | HUE031199T2 (pt) |
| IL (1) | IL200277A0 (pt) |
| PL (1) | PL2117502T3 (pt) |
| PT (1) | PT2117502T (pt) |
| RU (1) | RU2473327C2 (pt) |
| WO (1) | WO2008102150A2 (pt) |
| ZA (1) | ZA200905519B (pt) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2447012B (en) | 2007-02-21 | 2011-03-16 | Pharmacure Health Care Ab | Composition for combating epistaxis |
| USD993736S1 (en) | 2023-05-17 | 2023-08-01 | Line Work Bucket Products, LLC | Auger and socket holder |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4363319A (en) | 1980-06-30 | 1982-12-14 | Applied Medical Devices, Inc. | Ready-to-use bandage incorporating a coagulant composition and method of preparing same |
| JPS63174924A (ja) * | 1987-01-14 | 1988-07-19 | Toko Yakuhin Kogyo Kk | 軟膏基剤および軟膏剤 |
| JPH07500095A (ja) * | 1991-10-11 | 1995-01-05 | ノボ ノルディスク アクティーゼルスカブ | 局所止血用止血組成物 |
| CN1091315A (zh) * | 1992-10-08 | 1994-08-31 | E·R·斯奎布父子公司 | 血纤维蛋白封闭剂组合物及其使用方法 |
| US5928611A (en) * | 1995-06-07 | 1999-07-27 | Closure Medical Corporation | Impregnated applicator tip |
| US6365131B1 (en) * | 1997-10-31 | 2002-04-02 | J. B. Chemicals & Pharmaceuticals Ltd. | Pharmaceutical dental formulation for topical application of metronidazole benzoate, chlorhexidine gluconate and local anesthetic |
| US6818018B1 (en) * | 1998-08-14 | 2004-11-16 | Incept Llc | In situ polymerizable hydrogels |
| WO2001000218A1 (en) * | 1999-06-30 | 2001-01-04 | Scott Cordray | Nasal spray having dead sea salts |
| US20050232868A1 (en) * | 1999-10-19 | 2005-10-20 | The Procter & Gamble Company | Methods of entrapping, inactivating, and removing viral infections by the administration of respiratory tract compositions |
| US20030077301A1 (en) * | 1999-12-16 | 2003-04-24 | Maibach Howard I. | Topical pharmaceutical composition for the treatment of inflammatory dermatoses |
| RU2156612C1 (ru) * | 2000-03-13 | 2000-09-27 | Волков Александр Григорьевич | Способ остановки носового кровотечения |
| US7544348B2 (en) * | 2001-02-15 | 2009-06-09 | Access Pharmaceuticals, Inc. | Liquid formulations for the prevention and treatment of mucosal diseases and disorders |
| AU2002350088A1 (en) * | 2001-06-22 | 2003-01-08 | Millard Marsden Mershon | Compositions and methods for reducing blood and fluid loss from open wounds |
| DE10361306A1 (de) * | 2003-12-24 | 2005-07-28 | Lts Lohmann Therapie-Systeme Ag | Wundauflage und Wundschnellverband mit einem vasokonstriktorischen Inhaltsstoff, sowie Herstellungsverfahren hierfür |
| RU2369408C2 (ru) * | 2004-07-09 | 2009-10-10 | Ферросан А/С | Гемостатическая композиция, включающая гиалуроновую кислоту |
| GB2409162B (en) | 2004-10-06 | 2005-12-14 | Bhk Holding Ltd | Materials,methods,and apparatus for treating a body cavity |
| RU2290937C1 (ru) * | 2005-10-03 | 2007-01-10 | Владислав Владимирович Петров | Способ остановки носового кровотечения |
| GB2447012B (en) | 2007-02-21 | 2011-03-16 | Pharmacure Health Care Ab | Composition for combating epistaxis |
-
2007
- 2007-02-21 GB GB0703377A patent/GB2447012B/en not_active Expired - Fee Related
-
2008
- 2008-02-21 EP EP08709491.8A patent/EP2117502B1/en active Active
- 2008-02-21 PT PT87094918T patent/PT2117502T/pt unknown
- 2008-02-21 CN CN200880005428.8A patent/CN101677940B/zh not_active Expired - Fee Related
- 2008-02-21 BR BRPI0807732A patent/BRPI0807732B8/pt not_active IP Right Cessation
- 2008-02-21 PL PL08709491T patent/PL2117502T3/pl unknown
- 2008-02-21 WO PCT/GB2008/000608 patent/WO2008102150A2/en not_active Ceased
- 2008-02-21 US US12/525,975 patent/US9138406B2/en active Active
- 2008-02-21 HR HRP20161626TT patent/HRP20161626T1/hr unknown
- 2008-02-21 KR KR1020097019543A patent/KR20090130001A/ko not_active Ceased
- 2008-02-21 AU AU2008217608A patent/AU2008217608B2/en not_active Ceased
- 2008-02-21 JP JP2009550758A patent/JP2010519285A/ja active Pending
- 2008-02-21 ES ES08709491.8T patent/ES2606947T3/es active Active
- 2008-02-21 CA CA2678706A patent/CA2678706C/en active Active
- 2008-02-21 HU HUE08709491A patent/HUE031199T2/en unknown
- 2008-02-21 DK DK08709491.8T patent/DK2117502T3/en active
- 2008-02-21 ZA ZA200905519A patent/ZA200905519B/xx unknown
- 2008-02-21 RU RU2009134086/15A patent/RU2473327C2/ru not_active IP Right Cessation
-
2009
- 2009-08-06 IL IL200277A patent/IL200277A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HUE031199T2 (en) | 2017-07-28 |
| CA2678706C (en) | 2014-11-18 |
| PL2117502T3 (pl) | 2017-08-31 |
| BRPI0807732A2 (pt) | 2014-06-03 |
| GB0703377D0 (en) | 2007-03-28 |
| KR20090130001A (ko) | 2009-12-17 |
| AU2008217608B2 (en) | 2013-01-10 |
| ZA200905519B (en) | 2010-10-27 |
| PT2117502T (pt) | 2016-12-13 |
| CN101677940B (zh) | 2014-02-19 |
| RU2473327C2 (ru) | 2013-01-27 |
| US9138406B2 (en) | 2015-09-22 |
| DK2117502T3 (en) | 2017-01-23 |
| HRP20161626T1 (hr) | 2017-03-10 |
| US20100119472A1 (en) | 2010-05-13 |
| GB2447012A (en) | 2008-09-03 |
| EP2117502A2 (en) | 2009-11-18 |
| CA2678706A1 (en) | 2008-08-28 |
| ES2606947T3 (es) | 2017-03-28 |
| RU2009134086A (ru) | 2011-03-27 |
| JP2010519285A (ja) | 2010-06-03 |
| CN101677940A (zh) | 2010-03-24 |
| WO2008102150A2 (en) | 2008-08-28 |
| BRPI0807732B1 (pt) | 2020-08-04 |
| EP2117502B1 (en) | 2016-11-09 |
| GB2447012B (en) | 2011-03-16 |
| IL200277A0 (en) | 2010-04-29 |
| AU2008217608A1 (en) | 2008-08-28 |
| WO2008102150A3 (en) | 2009-04-30 |
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Legal Events
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| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
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| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
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| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B15K | Others concerning applications: alteration of classification |
Free format text: AS CLASSIFICACOES ANTERIORES ERAM: A61K 9/00 , A61K 9/06 , A61K 9/70 , A61K 47/02 , A61K 47/10 , A61K 47/18 Ipc: A61K 33/14 (2006.01), A61K 47/18 (2017.01), A61K 4 |
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| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 04/08/2020, OBSERVADAS AS CONDICOES LEGAIS. |
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Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 21/02/2008 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF |
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| B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
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