BRPI0809754A2 - método para produção de 1-butanol - Google Patents
método para produção de 1-butanolInfo
- Publication number
- BRPI0809754A2 BRPI0809754A2 BRPI0809754A BRPI0809754A BRPI0809754A2 BR PI0809754 A2 BRPI0809754 A2 BR PI0809754A2 BR PI0809754 A BRPI0809754 A BR PI0809754A BR PI0809754 A BRPI0809754 A BR PI0809754A BR PI0809754 A2 BRPI0809754 A2 BR PI0809754A2
- Authority
- BR
- Brazil
- Prior art keywords
- butanol
- butanol production
- producing
- production host
- fermentation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/16—Butanols
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y103/00—Oxidoreductases acting on the CH-CH group of donors (1.3)
- C12Y103/01—Oxidoreductases acting on the CH-CH group of donors (1.3) with NAD+ or NADP+ as acceptor (1.3.1)
- C12Y103/01038—Trans-2-enoyl-CoA reductase (NADPH) (1.3.1.38)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y103/00—Oxidoreductases acting on the CH-CH group of donors (1.3)
- C12Y103/01—Oxidoreductases acting on the CH-CH group of donors (1.3) with NAD+ or NADP+ as acceptor (1.3.1)
- C12Y103/01044—Trans-2-enoyl-CoA reductase (NAD+) (1.3.1.44)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y402/00—Carbon-oxygen lyases (4.2)
- C12Y402/01—Hydro-lyases (4.2.1)
- C12Y402/01017—Enoyl-CoA hydratase (4.2.1.17), i.e. crotonase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y402/00—Carbon-oxygen lyases (4.2)
- C12Y402/01—Hydro-lyases (4.2.1)
- C12Y402/01055—3-Hydroxybutyryl-CoA dehydratase (4.2.1.55)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
"método para produzir 1-butanol" a presente invenção trata de um método para produção de 1-butanol por fermentação, utilizando-se um hospedeiro microbiano de produção. o método emprega uma redução na temperatura durante o processo de fermentação, que resulta em maior tolerância do hospedeiro de produção ao produto 1-butanol.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US91545507P | 2007-05-02 | 2007-05-02 | |
| PCT/US2008/061855 WO2008137402A1 (en) | 2007-05-02 | 2008-04-29 | Method for the production of 1-butanol |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0809754A2 true BRPI0809754A2 (pt) | 2019-03-06 |
Family
ID=39643017
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0809754A BRPI0809754A2 (pt) | 2007-05-02 | 2008-04-29 | método para produção de 1-butanol |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US8426173B2 (pt) |
| EP (1) | EP2142656B1 (pt) |
| BR (1) | BRPI0809754A2 (pt) |
| CA (1) | CA2685151A1 (pt) |
| WO (1) | WO2008137402A1 (pt) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9297028B2 (en) * | 2005-09-29 | 2016-03-29 | Butamax Advanced Biofuels Llc | Fermentive production of four carbon alcohols |
| US8273558B2 (en) | 2005-10-26 | 2012-09-25 | Butamax(Tm) Advanced Biofuels Llc | Fermentive production of four carbon alcohols |
| EP2041266A4 (en) * | 2006-07-06 | 2009-12-23 | Integrated Genomics Inc | COMPOSITIONS AND METHOD FOR BUTANEAN MANUFACTURE |
| US20090155869A1 (en) * | 2006-12-01 | 2009-06-18 | Gevo, Inc. | Engineered microorganisms for producing n-butanol and related methods |
| BRPI0823327A2 (pt) | 2007-03-16 | 2013-10-22 | Genomatica Inc | Biocatalisadores microbianos que não ocorrem naturalmente e métodos para a biosíntese de ácido 4-hidroxibutanóico e 1,4-butanodiol |
| US8426173B2 (en) * | 2007-05-02 | 2013-04-23 | Butamax (Tm) Advanced Biofuels Llc | Method for the production of 1-butanol |
| US7947483B2 (en) | 2007-08-10 | 2011-05-24 | Genomatica, Inc. | Methods and organisms for the growth-coupled production of 1,4-butanediol |
| EP2250273B1 (en) | 2008-02-28 | 2016-04-13 | Green Biologics Limited | Enzymatic production of C4-C8 alcohols and acids |
| US20090238920A1 (en) * | 2008-03-21 | 2009-09-24 | Lewis Ted C | Process for making high grade protein product |
| US8188250B2 (en) | 2008-04-28 | 2012-05-29 | Butamax(Tm) Advanced Biofuels Llc | Butanol dehydrogenase enzyme from the bacterium Achromobacter xylosoxidans |
| EP3514242A3 (en) | 2008-09-10 | 2019-08-28 | Genomatica, Inc. | Microrganisms for the production of 1,4-butanediol |
| WO2010030332A1 (en) * | 2008-09-11 | 2010-03-18 | Superbulbs, Inc. | End-of-life bulb circuitry |
| US7833778B2 (en) * | 2009-02-23 | 2010-11-16 | Butler Iii Eugene T | Continuous single vessel butanol synthesis by fermentation |
| WO2010096065A1 (en) * | 2009-02-23 | 2010-08-26 | Butler Eugene T Iii | Continuous single vessel butanol synthesis by fermentation |
| DK3399019T3 (da) | 2009-02-26 | 2021-06-28 | Lanzatech New Zealand Ltd | Fremgangsmåder til bevaring af kulturs levedygtighed |
| US8178329B2 (en) * | 2009-04-01 | 2012-05-15 | Richard Allen Kohn | Process to produce organic compounds from synthesis gases |
| JP4760951B2 (ja) | 2009-05-08 | 2011-08-31 | トヨタ自動車株式会社 | ブタノール生産能を有する組換え微生物及びブタノールの製造方法 |
| WO2010141920A2 (en) | 2009-06-04 | 2010-12-09 | Genomatica, Inc. | Microorganisms for the production of 1,4-butanediol and related methods |
| LT2438036T (lt) | 2009-06-04 | 2017-06-26 | Genomatica, Inc. | Fermentacijos sultinio komponentų išskyrimo būdas |
| BR112012003241A2 (pt) * | 2009-08-12 | 2015-09-01 | Gevo Inc | Localização de via de isobutanol citosólico para a produção de isobutanol |
| KR20120083908A (ko) | 2009-10-13 | 2012-07-26 | 게노마티카 인코포레이티드 | 1,4-부탄다이올, 4-하이드록시부탄알, 4-하이드록시부티릴-coa, 푸트레신 및 관련 화합물의 제조를 위한 미생물 및 관련 방법 |
| US8530210B2 (en) | 2009-11-25 | 2013-09-10 | Genomatica, Inc. | Microorganisms and methods for the coproduction 1,4-butanediol and gamma-butyrolactone |
| US20110137088A1 (en) * | 2009-12-03 | 2011-06-09 | Bp Corporation North America Inc. | Methods and Apparatuses for Producing Renewable Materials From Inhibiting Compounds |
| US20110250629A1 (en) * | 2009-12-23 | 2011-10-13 | Lanza Tech New Zealand Limited | Alcohol production process |
| US8445244B2 (en) | 2010-02-23 | 2013-05-21 | Genomatica, Inc. | Methods for increasing product yields |
| US8048661B2 (en) | 2010-02-23 | 2011-11-01 | Genomatica, Inc. | Microbial organisms comprising exogenous nucleic acids encoding reductive TCA pathway enzymes |
| DE102010029973A1 (de) * | 2010-06-11 | 2011-12-15 | Evonik Degussa Gmbh | Mikrobiologische Herstellung von C4-Körpern aus Saccharose und Kohlendioxid |
| BR112012032172A2 (pt) | 2010-06-18 | 2015-11-24 | Butamax Tm Advanced Biofuels | método para produzir um álcool e composição |
| SG10201504733XA (en) | 2010-07-12 | 2015-07-30 | Univ Gent | Metabolically engineered organisms for the production of added value bio-products |
| US8895279B2 (en) | 2010-12-02 | 2014-11-25 | Dennis A. Burke | Applications of the rotating photobioreactor |
| WO2012135731A2 (en) * | 2011-04-01 | 2012-10-04 | The Regents Of The University Of California | Alcohol production from recombinant microorganisms |
| JP2015501643A (ja) | 2011-12-09 | 2015-01-19 | ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー | 発酵ブロスから生成物アルコールを取り出す方法 |
| US9689004B2 (en) | 2012-03-23 | 2017-06-27 | Butamax Advanced Biofuels Llc | Acetate supplemention of medium for butanologens |
| EP2844730A1 (en) | 2012-05-04 | 2015-03-11 | Butamax Advanced Biofuels LLC | Processes and systems for alcohol production and recovery |
| SI2855687T1 (sl) | 2012-06-04 | 2020-09-30 | Genomatica, Inc. | Mikroorganizmi in metode za proizvodnjo 4-hidroksibutirat, 1,4-butandiola in sorodne spojine |
| US9605281B2 (en) | 2012-09-12 | 2017-03-28 | Butamax Advanced Biofuels Llc | Processes and systems for the fermentative production of alcohols |
| AU2013295626B2 (en) | 2012-07-26 | 2018-02-01 | Butamax Advanced Biofuels Llc | Butanol purification |
| US9109196B2 (en) | 2012-09-12 | 2015-08-18 | Butamax Advanced Biofuels Llc | Processes and systems for the production of fermentation products |
| BR112015006296A2 (pt) | 2012-09-21 | 2017-07-04 | Butamax Advanced Biofuels Llc | ''processo, composição bifásica, métodos para a manutenção do estado oxidativo de uma composição, para otimizar a extração do butanol, para aprimorar o rendimento de uma fermetanção de isobutanol, para aprimorar o título de isobutanol produzido durante a fermentação e para aprimorar a taxa de produção de isobutanol durante uma fermentação'' |
| US9523104B2 (en) | 2013-03-12 | 2016-12-20 | Butamax Advanced Biofuels Llc | Processes and systems for the production of alcohols |
| WO2014151645A1 (en) * | 2013-03-15 | 2014-09-25 | Butamax Advanced Biofuels Llc | Process for maximizing biomass growth and butanol yield by feedback control |
| US9156760B2 (en) | 2013-03-15 | 2015-10-13 | Butamax Advanced Biofuels Llc | Method for production of butanol using extractive fermentation |
| WO2014144210A2 (en) | 2013-03-15 | 2014-09-18 | Butamax Advanced Biofuels Llc | Competitive growth and/or production advantage for butanologen microorganism |
| US9469584B2 (en) | 2013-03-15 | 2016-10-18 | Butamax Advanced Biofuels Llc | Method for producing butanol using extractive fermentation |
| WO2015002913A1 (en) | 2013-07-03 | 2015-01-08 | Butamax Advanced Biofuels Llc | Partial adaptation for butanol production |
| US10494597B2 (en) | 2014-04-11 | 2019-12-03 | Butamax Advanced Biofuels Llc | Contamination mitigation |
| AU2016222565A1 (en) | 2015-02-27 | 2017-09-28 | White Dog Labs, Inc. | Mixotrophic fermentation method for making acetone, isopropanol, butyric acid and other bioproducts, and mixtures thereof |
| JP2019523271A (ja) | 2016-07-27 | 2019-08-22 | エボニック デグサ ゲーエムベーハーEvonik Degussa GmbH | N−アセチルホモセリン |
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| US2198104A (en) * | 1938-12-15 | 1940-04-23 | Commercial Solvents Corp | Butyl alcohol fermentation process |
| US4424275A (en) * | 1979-09-17 | 1984-01-03 | Sidney Levy | Continuous process for producing N-butanol employing anaerobic fermentation |
| US4568643A (en) * | 1981-08-03 | 1986-02-04 | Sidney Levy | Continuous process for producing n-butanol employing anaerobic fermentation |
| US4520104A (en) * | 1982-11-18 | 1985-05-28 | Cpc International Inc. | Production of butanol by a continuous fermentation process |
| JPS61209594A (ja) | 1985-03-14 | 1986-09-17 | Res Assoc Petroleum Alternat Dev<Rapad> | アルコ−ルの製造方法 |
| JPS6317695A (ja) | 1986-07-09 | 1988-01-25 | Idemitsu Kosan Co Ltd | アルコ−ル類の製造法 |
| JPS63102687A (ja) | 1986-10-20 | 1988-05-07 | Res Assoc Petroleum Alternat Dev<Rapad> | ブタノ−ルの製造方法 |
| AT388174B (de) | 1987-03-10 | 1989-05-10 | Vogelbusch Gmbh | Verfahren zur vergaerung von kohlenhydrathaeltigen medien mit hilfe von bakterien |
| JPS63254986A (ja) | 1987-04-10 | 1988-10-21 | Res Assoc Petroleum Alternat Dev<Rapad> | アルコ−ルの製造法 |
| JPH084515B2 (ja) | 1987-11-09 | 1996-01-24 | 出光興産株式会社 | 有機化合物の製造方法 |
| US5424202A (en) * | 1988-08-31 | 1995-06-13 | The University Of Florida | Ethanol production by recombinant hosts |
| US5000000A (en) | 1988-08-31 | 1991-03-19 | University Of Florida | Ethanol production by Escherichia coli strains co-expressing Zymomonas PDC and ADH genes |
| US5192673A (en) * | 1990-04-30 | 1993-03-09 | Michigan Biotechnology Institute | Mutant strain of C. acetobutylicum and process for making butanol |
| US5063156A (en) * | 1990-04-30 | 1991-11-05 | Glassner David A | Process for the fermentative production of acetone, butanol and ethanol |
| US5210032A (en) * | 1992-01-21 | 1993-05-11 | Trustees Of The Boston University | Degeneration-resistant solventogenic clostridia |
| IL132883A0 (en) | 1997-05-14 | 2001-03-19 | Univ Illinois | A method of producing butanol using a mutant strain of clostridium beijerinckii |
| US6835820B2 (en) * | 1999-01-07 | 2004-12-28 | The University Of Massachusetts | Polyhydroxyalkanoate biosynthesis associated proteins and coding region in bacillus megaterium |
| EP1149918A1 (de) * | 2000-04-27 | 2001-10-31 | Creavis Gesellschaft für Technologie und Innovation mbH | Verfahren zur Oxidation von Kohlenwasserstoffen unter Verwendung von Mikroorganismen |
| US6960465B1 (en) * | 2001-06-27 | 2005-11-01 | Northwestern University | Increased cell resistance to toxic organic substances |
| CN102210376B (zh) * | 2003-03-10 | 2014-12-31 | 波伊特研究股份有限公司 | 利用生淀粉生产乙醇的方法 |
| US9297028B2 (en) * | 2005-09-29 | 2016-03-29 | Butamax Advanced Biofuels Llc | Fermentive production of four carbon alcohols |
| US7659104B2 (en) * | 2006-05-05 | 2010-02-09 | E.I. Du Pont De Nemours And Company | Solvent tolerant microorganisms and methods of isolation |
| US7541173B2 (en) * | 2006-06-15 | 2009-06-02 | E.I. Du Pont De Nemours And Company | Solvent tolerant microorganisms and methods of isolation |
| EP2041266A4 (en) | 2006-07-06 | 2009-12-23 | Integrated Genomics Inc | COMPOSITIONS AND METHOD FOR BUTANEAN MANUFACTURE |
| US20080293101A1 (en) * | 2006-07-27 | 2008-11-27 | Peters Matthew W | Engineered microorganisms for increasing product yield in biotransformations, related methods and systems |
| EP2097528A2 (en) | 2006-10-31 | 2009-09-09 | DSMIP Assets B.V. | Butanol production in a eukaryotic cell |
| US8017364B2 (en) * | 2006-12-12 | 2011-09-13 | Butamax(Tm) Advanced Biofuels Llc | Solvent tolerant microorganisms |
| KR100971793B1 (ko) | 2006-12-15 | 2010-07-21 | 바이오퓨얼켐 주식회사 | Butyryl-CoA를 중간체로 하여 부탄올을 생합성하는 능력을 가지는 박테리아를 이용하여 부탄올을 제조하는 방법 |
| US8426173B2 (en) * | 2007-05-02 | 2013-04-23 | Butamax (Tm) Advanced Biofuels Llc | Method for the production of 1-butanol |
-
2008
- 2008-04-28 US US12/110,503 patent/US8426173B2/en active Active
- 2008-04-29 CA CA002685151A patent/CA2685151A1/en not_active Abandoned
- 2008-04-29 WO PCT/US2008/061855 patent/WO2008137402A1/en not_active Ceased
- 2008-04-29 EP EP08747082.9A patent/EP2142656B1/en not_active Not-in-force
- 2008-04-29 BR BRPI0809754A patent/BRPI0809754A2/pt not_active IP Right Cessation
-
2013
- 2013-04-15 US US13/862,626 patent/US20130217060A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008137402A1 (en) | 2008-11-13 |
| EP2142656B1 (en) | 2015-04-08 |
| CA2685151A1 (en) | 2008-11-13 |
| US20080274524A1 (en) | 2008-11-06 |
| EP2142656A1 (en) | 2010-01-13 |
| US20130217060A1 (en) | 2013-08-22 |
| US8426173B2 (en) | 2013-04-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B25A | Requested transfer of rights approved |
Owner name: BUTAMAX ADVANCED BIOFUELS LLC (US) |
|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
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