BRPI0810632A2 - Derivados de piridopirazina, processo de fabricação e usos dos mesmos - Google Patents

Derivados de piridopirazina, processo de fabricação e usos dos mesmos

Info

Publication number: BRPI0810632A2
Authority: BR; Brazil
Prior art keywords: pyropyrozine; derivatives; manufacturing process; manufacturing; pyropyrozine derivatives
Prior art date: 2007-05-10

Application number

BRPI0810632-0A2A

Other languages

English (en)

Inventor

Matthias Gerlach

Irene Seipelt

Eckhard Guenther

Emmanuel Polymeropoulos

Tilmann Schuster

Eckhard Claus

Original Assignee

Aeterna Zentaris Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-05-10

Filing date

2008-05-09

Publication date

2014-11-04

2008-05-09 Application filed by Aeterna Zentaris Gmbh filed Critical Aeterna Zentaris Gmbh

2014-11-04 Publication of BRPI0810632A2 publication Critical patent/BRPI0810632A2/pt

Links

238000004519 manufacturing process Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
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- C07—ORGANIC CHEMISTRY
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- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Diabetes (AREA)
Pulmonology (AREA)
Hematology (AREA)
Cardiology (AREA)
Endocrinology (AREA)
Neurology (AREA)
Obesity (AREA)
Heart & Thoracic Surgery (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Urology & Nephrology (AREA)
Reproductive Health (AREA)
Dermatology (AREA)
Oncology (AREA)
Rheumatology (AREA)
Hospice & Palliative Care (AREA)
Physical Education & Sports Medicine (AREA)
Pain & Pain Management (AREA)
Orthopedic Medicine & Surgery (AREA)
Emergency Medicine (AREA)
Otolaryngology (AREA)
Virology (AREA)
Communicable Diseases (AREA)
Ophthalmology & Optometry (AREA)

BRPI0810632-0A2A 2007-05-10 2008-05-09 Derivados de piridopirazina, processo de fabricação e usos dos mesmos BRPI0810632A2 (pt)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US91712907P	2007-05-10	2007-05-10
EP07107976A EP1990342A1 (en)	2007-05-10	2007-05-10	Pyridopyrazine Derivatives, Process of Manufacturing and Uses thereof
PCT/EP2008/055728 WO2008138878A2 (en)	2007-05-10	2008-05-09	Novel pyridopyrazine derivatives, process of manufacturing and uses thereof

Publications (1)

Publication Number	Publication Date
BRPI0810632A2 true BRPI0810632A2 (pt)	2014-11-04

Family

ID=38617324

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0810632-0A2A BRPI0810632A2 (pt)	2007-05-10	2008-05-09	Derivados de piridopirazina, processo de fabricação e usos dos mesmos

Country Status (18)

Country	Link
US (4)	US8202883B2 (pt)
EP (2)	EP1990342A1 (pt)
JP (3)	JP5528326B2 (pt)
KR (1)	KR20100016425A (pt)
CN (1)	CN101715451B (pt)
AR (1)	AR067315A1 (pt)
AU (1)	AU2008250282B2 (pt)
BR (1)	BRPI0810632A2 (pt)
CA (1)	CA2686489C (pt)
IL (1)	IL201375A0 (pt)
MX (1)	MX2009012144A (pt)
NZ (1)	NZ580268A (pt)
RU (1)	RU2495038C2 (pt)
SG (1)	SG183692A1 (pt)
TW (1)	TWI432199B (pt)
UA (1)	UA99128C2 (pt)
WO (1)	WO2008138878A2 (pt)
ZA (1)	ZA200906861B (pt)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1990342A1 (en)	2007-05-10	2008-11-12	AEterna Zentaris GmbH	Pyridopyrazine Derivatives, Process of Manufacturing and Uses thereof
WO2010052448A2 (en) *	2008-11-05	2010-05-14	Ucb Pharma S.A.	Fused pyrazine derivatives as kinase inhibitors
EP2241557A1 (de) *	2009-04-02	2010-10-20	Æterna Zentaris GmbH	Chinoxalin-Derivate und deren Anwendung zur Behandlung gutartiger und bösartiger Tumorerkrankungen
US8575203B2 (en)	2010-04-21	2013-11-05	Boehringer Ingelheim International Gmbh	Chemical compounds
GB201007286D0 (en)	2010-04-30	2010-06-16	Astex Therapeutics Ltd	New compounds
GB201020179D0 (en)	2010-11-29	2011-01-12	Astex Therapeutics Ltd	New compounds
US9051318B2 (en)	2011-03-09	2015-06-09	Merck Patent Gmbh	Pyrido [2, 3-B] pyrazine compounds and their therapeutical uses such as for inhibiting ATP consuming proteins and treating diseases associated therewith
EP2508184A1 (en) *	2011-04-06	2012-10-10	Æterna Zentaris GmbH	Pyridopyrazine derivatives and their use
AR086744A1 (es) *	2011-06-28	2014-01-22	Nippon Soda Co	Compuesto heterociclico conteniendo nitrogeno y fungicida para el uso en agricultura y jardineria
JP5792128B2 (ja) *	2011-07-29	2015-10-07	富士フイルム株式会社	１，５−ナフチリジン誘導体又はその塩
GB201118656D0 (en) *	2011-10-28	2011-12-07	Astex Therapeutics Ltd	New compounds
GB201118654D0 (en)	2011-10-28	2011-12-07	Astex Therapeutics Ltd	New compounds
GB201118675D0 (en)	2011-10-28	2011-12-14	Astex Therapeutics Ltd	New compounds
GB201118652D0 (en)	2011-10-28	2011-12-07	Astex Therapeutics Ltd	New compounds
CN103159686A (zh) *	2011-12-09	2013-06-19	天津市国际生物医药联合研究院	一种hiv-1蛋白酶的脲类抑制剂
GB201209609D0 (en)	2012-05-30	2012-07-11	Astex Therapeutics Ltd	New compounds
GB201209613D0 (en)	2012-05-30	2012-07-11	Astex Therapeutics Ltd	New compounds
LT3495367T (lt)	2012-06-13	2021-02-25	Incyte Holdings Corporation	Pakeistieji tricikliniai junginiai, kaip fgfr inhibitoriai
HUE043663T2 (hu) *	2012-10-31	2019-08-28	Fujifilm Toyama Chemical Co Ltd	Új aminszármazék vagy sója TNF-alfa inhibitorként
WO2014109414A1 (ja)	2013-01-11	2014-07-17	富士フイルム株式会社	含窒素複素環化合物またはその塩
US9561228B2 (en)	2013-02-08	2017-02-07	Celgene Avilomics Research, Inc.	ERK inhibitors and uses thereof
LT2986610T (lt)	2013-04-19	2018-04-10	Incyte Holdings Corporation	Bicikliniai heterociklai, kaip fgfr inhibitoriai
GB201307577D0 (en)	2013-04-26	2013-06-12	Astex Therapeutics Ltd	New compounds
MA39784B1 (fr)	2014-03-26	2021-03-31	Astex Therapeutics Ltd	Combinaisons des inhibiteurs du fgfr et du cmet destinées au traitement du cancer
AU2015238305B2 (en)	2014-03-26	2020-06-18	Astex Therapeutics Ltd	Combinations of an FGFR inhibitor and an IGF1R inhibitor
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RU2495038C2 (ru)	2013-10-10
TW200908979A (en)	2009-03-01
NZ580268A (en)	2012-09-28
US20090275534A1 (en)	2009-11-05
JP5528326B2 (ja)	2014-06-25
US20120209050A1 (en)	2012-08-16
CA2686489A1 (en)	2008-11-20
TWI432199B (zh)	2014-04-01
US8202883B2 (en)	2012-06-19
US8507486B2 (en)	2013-08-13
EP2164849A2 (en)	2010-03-24
WO2008138878A3 (en)	2009-03-19
KR20100016425A (ko)	2010-02-12
AU2008250282B2 (en)	2013-09-19
EP1990342A1 (en)	2008-11-12
US20120214768A1 (en)	2012-08-23
ZA200906861B (en)	2010-06-30
JP2014074068A (ja)	2014-04-24
UA99128C2 (ru)	2012-07-25
SG183692A1 (en)	2012-09-27
CN101715451B (zh)	2013-07-31
HK1140202A1 (en)	2010-10-08
CN101715451A (zh)	2010-05-26
WO2008138878A2 (en)	2008-11-20
CA2686489C (en)	2014-07-15
JP2010526794A (ja)	2010-08-05
AR067315A1 (es)	2009-10-07
US8604196B2 (en)	2013-12-10
IL201375A0 (en)	2010-05-31
JP2014062137A (ja)	2014-04-10
US8536332B2 (en)	2013-09-17
RU2009145811A (ru)	2011-06-20
US20120277219A1 (en)	2012-11-01
MX2009012144A (es)	2009-11-23
AU2008250282A1 (en)	2008-11-20

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