BRPI0810814A2 - Formas sólidas de dosagem incluindo tadalafil - Google Patents

Formas sólidas de dosagem incluindo tadalafil

Info

Publication number: BRPI0810814A2
Authority: BR; Brazil
Prior art keywords: dosage forms; solid dosage; forms including; including tadalafil; tadalafil
Prior art date: 2007-04-25

Application number

BRPI0810814-5A2A

Other languages

English (en)

Inventor

Ilan Zalit

Yonit Triger-Messer

Original Assignee

Teva Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-04-25

Filing date

2008-04-25

Publication date

2014-10-29

2008-04-25 Application filed by Teva Pharma filed Critical Teva Pharma

2014-10-29 Publication of BRPI0810814A2 publication Critical patent/BRPI0810814A2/pt

Links

239000007909 solid dosage form Substances 0.000 title 1
IEHKWSGCTWLXFU-IIBYNOLFSA-N tadalafil Chemical compound C1=C2OCOC2=CC([C@@H]2C3=C([C]4C=CC=CC4=N3)C[C@H]3N2C(=O)CN(C3=O)C)=C1 IEHKWSGCTWLXFU-IIBYNOLFSA-N 0.000 title 1
229960000835 tadalafil Drugs 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0007—Effervescent
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Reproductive Health (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Endocrinology (AREA)
Gynecology & Obstetrics (AREA)
Inorganic Chemistry (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

BRPI0810814-5A2A 2007-04-25 2008-04-25 Formas sólidas de dosagem incluindo tadalafil BRPI0810814A2 (pt)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US92640307P	2007-04-25	2007-04-25
US93144907P	2007-05-22	2007-05-22
PCT/US2008/061638 WO2008134557A2 (en)	2007-04-25	2008-04-25	Solid dosage forms

Publications (1)

Publication Number	Publication Date
BRPI0810814A2 true BRPI0810814A2 (pt)	2014-10-29

Family

ID=39529683

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0810814-5A2A BRPI0810814A2 (pt)	2007-04-25	2008-04-25	Formas sólidas de dosagem incluindo tadalafil

Country Status (12)

Country	Link
US (1)	US20090098211A1 (pt)
EP (1)	EP1985310B1 (pt)
JP (1)	JP2010525082A (pt)
KR (1)	KR20100012867A (pt)
CN (1)	CN101678114A (pt)
AU (1)	AU2008245597A1 (pt)
BR (1)	BRPI0810814A2 (pt)
CA (1)	CA2685184A1 (pt)
ES (1)	ES2405787T3 (pt)
MX (1)	MX2009011588A (pt)
RU (1)	RU2456989C2 (pt)
WO (1)	WO2008134557A2 (pt)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20080009502A1 (en) *	2006-07-07	2008-01-10	Access Business Group International Llc	Tadalafil solid composites
DE102007028869A1 (de)	2007-06-22	2008-12-24	Ratiopharm Gmbh	Verfahren zur Herstellung eines Arzneimittels enthaltend Tadalafil
EP2393489B1 (en) *	2009-02-05	2014-10-08	Krka, tovarna zdravil, d.d., Novo mesto	Moisture-activated granulation process
EP2238979A1 (en) *	2009-04-06	2010-10-13	LEK Pharmaceuticals d.d.	Active pharmaceutical ingredient adsorbed on solid support
US20110136815A1 (en) *	2009-12-08	2011-06-09	Horst Zerbe	Solid oral film dosage forms and methods for making same
US10610528B2 (en)	2009-12-08	2020-04-07	Intelgenx Corp.	Solid oral film dosage forms and methods for making same
US20110263606A1 (en) *	2010-04-26	2011-10-27	Horst Zerbe	Solid oral dosage forms comprising tadalafil
WO2012095151A1 (en) *	2010-12-23	2012-07-19	Zaklady Farmaceutyczne Polpharma Sa	Solid pharmaceutical dosage forms comprising tadalafil and methods of preparation thereof
WO2012107092A1 (en)	2011-02-10	2012-08-16	Synthon Bv	Pharmaceutical composition comprising tadalafil and a cyclodextrin
WO2012107090A1 (en)	2011-02-10	2012-08-16	Synthon Bv	Granulated composition comprising tadalafil and a disintegrant
WO2013109230A1 (en) *	2012-01-18	2013-07-25	Mahmut Bilgic	Pharmaceutical compositions comprising tadalafil
WO2013109223A1 (en) *	2012-01-18	2013-07-25	Mahmut Bilgic	Particulate formulations of tadalafil in effervescent form
WO2014125343A1 (en) *	2013-02-12	2014-08-21	Alembic Pharmaceuticals Limited	Tadalafil tablet composition with reduced dose strength
WO2014125352A1 (en) *	2013-02-14	2014-08-21	Aurobindo Pharma Limited	Pharmaceutical compositions comprising tadalafil
KR102239291B1 (ko) *	2013-06-28	2021-04-14	한미약품 주식회사	타다라필 또는 이의 약학적으로 허용가능한 염을 포함하는 저작정 제제
WO2015072700A1 (en) *	2013-11-15	2015-05-21	Hanmi Pharm. Co., Ltd.	Composite formulation comprising tadalafil and amlodipine
KR20150056443A (ko) *	2013-11-15	2015-05-26	한미약품 주식회사	타다라필 및 암로디핀을 포함하는 복합제제
ES2699160T3 (es) *	2014-06-24	2019-02-07	Wooshin Labottach Co Ltd	Formulación de película de desintegración oral que contiene tadalafilo y procedimiento de preparación de la misma
EP3466951B1 (en)	2014-07-23	2022-01-19	KRKA, d.d., Novo mesto	A process for the preparation of cgmp-phosphodiesterase inhibitor and oral pharmaceutical formulation comprising tadalafil co-precipitates
KR101648051B1 (ko)	2014-09-01	2016-08-12	주식회사 인트로팜텍	타다라필을 포함하는 휴대용 구강붕해정, 및 이의 제조방법
KR101538985B1 (ko) *	2014-09-02	2015-07-24	주식회사 서울제약	타다라필 구강붕해필름 및 이의 제조방법
CN107303284A (zh) *	2016-04-25	2017-10-31	湖北生物医药产业技术研究院有限公司	制备他达拉非片剂的方法及他达拉非片剂
EA028561B1 (ru) *	2016-12-28	2017-11-30	Тева Фармасьютикал Индастриз, Лтд.	Твердые лекарственные формы тадалафила
US20210137919A1 (en) *	2018-02-07	2021-05-13	Smawa Gmbh	Pharmaceutical formulations, method for producing a pharmaceutical formulation, and medicament comprising same
US10828254B2 (en) *	2018-09-28	2020-11-10	Intelgenx Corp.	Oral film formulation for modulating absorption profile
ES3038192T3 (en) *	2019-08-08	2025-10-10	Evonik Operations Gmbh	Method of preparing a solid dosage form and a lubricant
CN110638770B (zh) *	2019-10-25	2022-04-05	株洲千金药业股份有限公司	他达拉非片剂的制备方法及以该方法制得的片剂
PE20240764A1 (es) *	2021-04-16	2024-04-17	Lg Chemical Ltd	Formulacion compuesta para administracion oral que comprende acido 1-(3-ciano-1-isopropil-indol-5-il)pirazol-4-carboxilico

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9401090D0 (en) *	1994-01-21	1994-03-16	Glaxo Lab Sa	Chemical compounds
GB9511220D0 (en)	1995-06-02	1995-07-26	Glaxo Group Ltd	Solid dispersions
GB9514464D0 (en) *	1995-07-14	1995-09-13	Glaxo Lab Sa	Medicaments
ATE399554T1 (de)	1999-08-03	2008-07-15	Lilly Icos Llc	Pharmazeutische zusammensetzung enthaltend tadalafil
US6821975B1 (en) *	1999-08-03	2004-11-23	Lilly Icos Llc	Beta-carboline drug products
CA2474190A1 (en) *	2002-02-07	2003-08-14	Pharmacia Corporation	Pharmaceutical dosage form for mucosal delivery
MXPA05001707A (es) *	2002-08-30	2005-04-19	Pharmacia Corp	Formas de dosificacion farmaceutica solidas que presentan un perfil de liberacion de farmaco reproducible,.
US20050196418A1 (en) *	2004-03-04	2005-09-08	Yu Ruey J.	Bioavailability and improved delivery of alkaline pharmaceutical drugs
US20060276442A1 (en) *	2004-09-08	2006-12-07	Woodward John R	Methods of female sexual enhancement
US8367105B2 (en)	2004-11-10	2013-02-05	Teva Pharmaceutical Industries, Ltd.	Compressed solid dosage form manufacturing process well-suited for use with drugs of low aqueous solubility and compressed solid dosage forms made thereby
CN1742732A (zh) *	2005-09-20	2006-03-08	杭州恒丰医药科技有限公司	西力士滴丸及其制备方法
US20080009502A1 (en) *	2006-07-07	2008-01-10	Access Business Group International Llc	Tadalafil solid composites

2008
- 2008-04-25 ES ES08251529T patent/ES2405787T3/es active Active
- 2008-04-25 JP JP2010506534A patent/JP2010525082A/ja active Pending
- 2008-04-25 CA CA002685184A patent/CA2685184A1/en not_active Abandoned
- 2008-04-25 EP EP08251529A patent/EP1985310B1/en not_active Not-in-force
- 2008-04-25 AU AU2008245597A patent/AU2008245597A1/en not_active Abandoned
- 2008-04-25 MX MX2009011588A patent/MX2009011588A/es unknown
- 2008-04-25 KR KR1020097024010A patent/KR20100012867A/ko not_active Abandoned
- 2008-04-25 BR BRPI0810814-5A2A patent/BRPI0810814A2/pt not_active IP Right Cessation
- 2008-04-25 WO PCT/US2008/061638 patent/WO2008134557A2/en not_active Ceased
- 2008-04-25 US US12/110,029 patent/US20090098211A1/en not_active Abandoned
- 2008-04-25 RU RU2009141538/15A patent/RU2456989C2/ru active
- 2008-04-25 CN CN200880021162A patent/CN101678114A/zh active Pending

Also Published As

Publication number	Publication date
CA2685184A1 (en)	2008-11-06
WO2008134557A3 (en)	2009-02-05
US20090098211A1 (en)	2009-04-16
WO2008134557A2 (en)	2008-11-06
RU2009141538A (ru)	2011-05-27
CN101678114A (zh)	2010-03-24
ES2405787T3 (es)	2013-06-03
MX2009011588A (es)	2009-11-05
KR20100012867A (ko)	2010-02-08
AU2008245597A1 (en)	2008-11-06
RU2456989C2 (ru)	2012-07-27
EP1985310B1 (en)	2013-03-20
EP1985310A1 (en)	2008-10-29
JP2010525082A (ja)	2010-07-22

Legal Events

Date	Code	Title	Description
2015-08-25	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]	Free format text: REFERENTE A 7A ANUIDADE.
2016-05-10	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2329 DE 25-08-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.
2022-07-12	B350	Update of information on the portal [chapter 15.35 patent gazette]

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ATE501136T1 (de)	2011-03-15	Imidazopyridinone
DE502007001207D1 (de)	2009-09-10	Elektrosaugkopf
EP2233838A4 (en)	2013-01-09	COOKER
ATE514696T1 (de)	2011-07-15	Diphenyl-dihydro-imidazopyridinone
DE112008003636A5 (de)	2010-10-21	Mehrzuggruppierer
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AT505058A3 (de)	2008-12-15	Türschliesssystem
BRPI0922806A2 (pt)	2015-12-22	formas de dosagem oral de bendamustina
EP2197448A4 (en)	2010-11-17	dosing schedule
BRPI0821735A2 (pt)	2015-06-16	Fabricação de tablete
BRPI0807882A2 (pt)	2014-06-17	Forma de dosagem
DE112008001216A5 (de)	2010-02-04	Magnetronplasmaanlage
DE112008003094A5 (de)	2010-08-12	Geomatte
DE112008003196A5 (de)	2011-02-03	Handpipettiergerät