BRPI0821573A2 - benzofuropirimidonas - Google Patents

benzofuropirimidonas

Info

Publication number: BRPI0821573A2
Authority: BR; Brazil
Prior art keywords: benzofuropyrimidones
Prior art date: 2007-12-21

Application number

BRPI0821573A

Other languages

English (en)

Inventor

Adam Antoni Galan

Amy L Tsuhako

Cristina A Zaharia

Elena S Koltun

Hongwang Du

Maurizio Franzini

Moon Hwan Kim

Patrick Kearney

Ping Huang

S David Brown

Steven James Richards

Original Assignee

Exelixis Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-12-21

Filing date

2008-12-22

Publication date

2016-08-09

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40383673&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0821573(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2008-12-22 Application filed by Exelixis Inc filed Critical Exelixis Inc

2016-08-09 Publication of BRPI0821573A2 publication Critical patent/BRPI0821573A2/pt

Links

LPJFETZUCIPKPG-UHFFFAOYSA-N 1h-[1]benzofuro[3,2-d]pyrimidin-2-one Chemical class C1=CC=C2C3=NC(=O)NC=C3OC2=C1 LPJFETZUCIPKPG-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Hematology (AREA)
Oncology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

BRPI0821573A 2007-12-21 2008-12-22 benzofuropirimidonas BRPI0821573A2 (pt)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US890707P	2007-12-21	2007-12-21
US7097108P	2008-03-25	2008-03-25
PCT/US2008/087939 WO2009086264A1 (en)	2007-12-21	2008-12-22	Benzofuropyrimidinones as protein kinase inhibitors

Publications (1)

Publication Number	Publication Date
BRPI0821573A2 true BRPI0821573A2 (pt)	2016-08-09

Family

ID=40383673

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0821573A BRPI0821573A2 (pt)	2007-12-21	2008-12-22	benzofuropirimidonas

Country Status (20)

Country	Link
US (1)	US20090247559A1 (pt)
EP (1)	EP2097419B1 (pt)
JP (1)	JP2011507908A (pt)
KR (1)	KR20100098714A (pt)
CN (1)	CN101965351A (pt)
AR (1)	AR069869A1 (pt)
AT (1)	ATE510839T1 (pt)
AU (1)	AU2008345560A1 (pt)
BR (1)	BRPI0821573A2 (pt)
CA (1)	CA2712358A1 (pt)
CL (1)	CL2008003873A1 (pt)
CO (1)	CO6321258A2 (pt)
EA (1)	EA019785B1 (pt)
IL (1)	IL206416A0 (pt)
MX (1)	MX2010006799A (pt)
NZ (1)	NZ586936A (pt)
PE (1)	PE20091669A1 (pt)
TW (1)	TW200930375A (pt)
WO (1)	WO2009086264A1 (pt)
ZA (1)	ZA201004243B (pt)

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DE102007026341A1 (de)	2007-06-06	2008-12-11	Merck Patent Gmbh	Benzoxazolonderivate
DE102007032507A1 (de)	2007-07-12	2009-04-02	Merck Patent Gmbh	Pyridazinonderivate
DE102007061963A1 (de)	2007-12-21	2009-06-25	Merck Patent Gmbh	Pyridazinonderivate
DE102008019907A1 (de)	2008-04-21	2009-10-22	Merck Patent Gmbh	Pyridazinonderivate
DE102008028905A1 (de)	2008-06-18	2009-12-24	Merck Patent Gmbh	3-(3-Pyrimidin-2-yl-benzyl)-[1,2,4]triazolo[4,3-b]pyridazinderivate
US9394333B2 (en)	2008-12-02	2016-07-19	Wave Life Sciences Japan	Method for the synthesis of phosphorus atom modified nucleic acids
US8586599B2 (en)	2008-12-22	2013-11-19	Merck Patent Gmbh	Polymorphic forms of 6-(1-methyl-1H-pyrazol-4-yl)-2-{3-[5-(2-morpholin-4-yl-ethoxy)-pyrimidin-2-yl]-benzyl}-2H-pyridazin-3-one dihydrogenphosphate and processes of manufacturing thereof
MX342945B (es)	2009-07-06	2016-10-18	Ontorii Inc *	Profármacos de ácido nucleico novedosos y métodos de uso de los mismos.
DK2620428T3 (da)	2010-09-24	2019-07-01	Wave Life Sciences Ltd	Asymmetrisk hjælpegruppe
US9605019B2 (en)	2011-07-19	2017-03-28	Wave Life Sciences Ltd.	Methods for the synthesis of functionalized nucleic acids
SG11201500239VA (en)	2012-07-13	2015-03-30	Wave Life Sciences Japan	Asymmetric auxiliary group
SG11201500243WA (en)	2012-07-13	2015-04-29	Shin Nippon Biomedical Lab Ltd	Chiral nucleic acid adjuvant
KR20240148947A (ko)	2012-07-13	2024-10-11	웨이브 라이프 사이언시스 리미티드	키랄 제어
CN102875558A (zh) *	2012-11-05	2013-01-16	贵州大学	2-氯-4-取代-8-硝基苯并呋喃[3,2-d]嘧啶类化合物及其制备方法和用途
CN103044370A (zh) *	2012-12-28	2013-04-17	山东邹平大展新材料有限公司	一种5-（哌嗪-1-基）苯并呋喃-2-甲酰胺的制备方法
CN104045642B (zh) *	2013-03-14	2016-08-24	上海医药工业研究院	含嘧啶或吡啶的稠环化合物及其作为抗肿瘤药物的应用
EP3095460A4 (en)	2014-01-15	2017-08-23	Shin Nippon Biomedical Laboratories, Ltd.	Chiral nucleic acid adjuvant having anti-allergic activity, and anti-allergic agent
WO2015108047A1 (ja)	2014-01-15	2015-07-23	株式会社新日本科学	免疫誘導活性を有するキラル核酸アジュバンド及び免疫誘導活性剤
WO2015108048A1 (ja)	2014-01-15	2015-07-23	株式会社新日本科学	抗腫瘍作用を有するキラル核酸アジュバンド及び抗腫瘍剤
ES2917473T3 (es)	2014-01-16	2022-07-08	Wave Life Sciences Ltd	Diseño quiral
JP6569908B2 (ja)	2014-01-31	2019-09-04	カルナバイオサイエンス株式会社	抗がん剤組成物
CN106255679B (zh)	2014-02-27	2019-09-06	默克专利有限公司	用作nav通道抑制剂的杂环化合物及其用途
WO2015152319A1 (ja) *	2014-04-02	2015-10-08	株式会社三和化学研究所	５，７－無置換－ピラゾロ［１，５－ａ］ピリミジン－６－カルボン酸の製造方法
KR101837565B1 (ko)	2014-08-06	2018-03-12	삼성에스디아이 주식회사	유기 화합물, 유기 광전자 소자 및 표시 장치
JP6840931B2 (ja) *	2015-03-09	2021-03-10	東ソー株式会社	縮環芳香族化合物の製造方法
US11020396B2 (en)	2016-11-08	2021-06-01	Cancer Research Technology Limited	Pyrimidinone derivatives as Cdc7 inhibitors
NL2021185B1 (en)	2018-06-26	2020-01-06	Stichting Het Nederlands Kanker Inst Antoni Van Leeuwenhoek Ziekenhuis	Combination Therapy and Use Thereof for Treating Cancer
US12533353B2 (en)	2018-09-24	2026-01-27	Carna Biosciences, Inc.	Methods of treatment of cancer comprising CDC7 inhibitors
MA53726A (fr)	2018-09-25	2022-05-11	Incyte Corp	Composés pyrazolo[4,3-d]pyrimidine en tant que modulateurs des alk2 et/ou fgfr
CN111689947B (zh) *	2019-03-13	2023-07-14	鲁南制药集团股份有限公司	替加氟-l-脯氨酸共晶体及其制备方法
CN115397423A (zh) *	2020-02-03	2022-11-25	增益治疗股份有限公司	用于治疗mps1的组合疗法
WO2021198191A1 (en)	2020-03-30	2021-10-07	Enyo Pharma	Quinazolinone derivatives and uses thereof for treating a cancer
MX2023003932A (es) *	2020-10-05	2023-04-26	Japan Tobacco Inc	Compuesto de tetrahidrobenzofurodiazepinona y uso farmaceutico del mismo.
CN117120447A (zh) *	2021-03-18	2023-11-24	薛定谔公司	环状化合物和其使用方法
WO2022194799A1 (de)	2021-03-18	2022-09-22	Merck Patent Gmbh	Heteroaromatische verbindungen für organische elektrolumineszenzvorrichtungen
WO2023156386A2 (en) *	2022-02-16	2023-08-24	Duke Street Bio Limited	Pharmaceutical compound
CN116731025B (zh) *	2023-05-24	2025-06-24	曲阜师范大学	一种具有2-芳基苯并呋喃并[2,3-d]嘧啶酮类结构的荧光材料及其制备方法和应用
CN120114459B (zh) *	2025-05-14	2025-07-29	南京工业大学	苯并呋喃嘧啶酮或苯并噻吩嘧啶酮类化合物的应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL112248A0 (en) *	1994-01-25	1995-03-30	Warner Lambert Co	Tricyclic heteroaromatic compounds and pharmaceutical compositions containing them
WO2002051849A1 (en)	2000-12-26	2002-07-04	Daiichi Pharmaceutical Co., Ltd.	Cdk4 inhibitors
JP2005504730A (ja) *	2001-04-20	2005-02-17	バーテックス　ファーマシューティカルズ　インコーポレイテッド	Ｇｓｋ−３インヒビターとして有用な組成物
US7345046B2 (en) *	2003-05-30	2008-03-18	Chiron Corporation	Heteroaryl-fused pyrimidinyl compounds as anticancer agents
WO2006023381A1 (en)	2004-08-16	2006-03-02	Taigen Biotechnology	Pyrimidinone compounds
US20080269239A1 (en)	2004-11-11	2008-10-30	Argenta Discovery Ltd.	Pyrimidine Compounds as Histamine Modulators
EP1776982A1 (en)	2005-10-18	2007-04-25	Argenta Discovery Limited	Pyrimidine compounds as histamine modulators

2008
- 2008-12-19 TW TW097149655A patent/TW200930375A/zh unknown
- 2008-12-19 PE PE2008002147A patent/PE20091669A1/es not_active Application Discontinuation
- 2008-12-19 AR ARP080105615A patent/AR069869A1/es unknown
- 2008-12-22 CA CA2712358A patent/CA2712358A1/en not_active Abandoned
- 2008-12-22 US US12/341,210 patent/US20090247559A1/en not_active Abandoned
- 2008-12-22 EP EP08832770A patent/EP2097419B1/en active Active
- 2008-12-22 AT AT08832770T patent/ATE510839T1/de not_active IP Right Cessation
- 2008-12-22 EA EA201070786A patent/EA019785B1/ru not_active IP Right Cessation
- 2008-12-22 CN CN2008801272275A patent/CN101965351A/zh active Pending
- 2008-12-22 CL CL2008003873A patent/CL2008003873A1/es unknown
- 2008-12-22 KR KR1020107016179A patent/KR20100098714A/ko not_active Ceased
- 2008-12-22 MX MX2010006799A patent/MX2010006799A/es active IP Right Grant
- 2008-12-22 WO PCT/US2008/087939 patent/WO2009086264A1/en not_active Ceased
- 2008-12-22 JP JP2010539930A patent/JP2011507908A/ja not_active Ceased
- 2008-12-22 AU AU2008345560A patent/AU2008345560A1/en not_active Abandoned
- 2008-12-22 BR BRPI0821573A patent/BRPI0821573A2/pt not_active IP Right Cessation
- 2008-12-22 NZ NZ586936A patent/NZ586936A/en not_active IP Right Cessation
2010
- 2010-06-15 ZA ZA2010/04243A patent/ZA201004243B/en unknown
- 2010-06-16 IL IL206416A patent/IL206416A0/en unknown
- 2010-07-21 CO CO10088575A patent/CO6321258A2/es not_active Application Discontinuation

Also Published As

Publication number	Publication date
AR069869A1 (es)	2010-02-24
EP2097419B1 (en)	2011-05-25
ZA201004243B (en)	2011-03-30
PE20091669A1 (es)	2009-12-06
CA2712358A1 (en)	2009-07-09
CO6321258A2 (es)	2011-09-20
IL206416A0 (en)	2010-12-30
KR20100098714A (ko)	2010-09-08
WO2009086264A1 (en)	2009-07-09
ATE510839T1 (de)	2011-06-15
MX2010006799A (es)	2010-10-05
EA201070786A1 (ru)	2011-02-28
TW200930375A (en)	2009-07-16
US20090247559A1 (en)	2009-10-01
CN101965351A (zh)	2011-02-02
NZ586936A (en)	2012-07-27
JP2011507908A (ja)	2011-03-10
CL2008003873A1 (es)	2009-06-26
EA019785B1 (ru)	2014-06-30
EP2097419A1 (en)	2009-09-09
AU2008345560A1 (en)	2009-07-09

Legal Events

Date	Code	Title	Description
2016-08-16	B15I	Others concerning applications: loss of priority	Free format text: PERDA DAS PRIORIDADES US 61/008907 DE 21/12/2007 E US 61/070971 DE 25/03/2008, CONFORME AS DISPOSICOES PREVISTAS NA LEI 9.279 DE 14/05/1996 (LPI) ART. 16 7O E NO ART. 28 DO ATO NORMATIVO 128/1997, POR NAO ATENDER AO DISPOSTO NO ART. 27 DO ATO NORMATIVO 128/1997, POIS NAO FOI APRESENTADA CESSAO DA REFERIDA PRIORIDADE, QUE POSSUI DEPOSITANTE DIFERENTE DO DEPOSITANTE DA FASE NACIONAL.
2016-09-06	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]	Free format text: REFERENTE AS 4A, 5A, 6A E 7A ANUIDADES.
2016-12-20	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2383 DE 06-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

Publication	Publication Date	Title
DE602008006301D1 (de)	2011-06-01	Koaxialnadelanordnung
BRPI0821573A2 (pt)	2016-08-09	benzofuropirimidonas
ATE501136T1 (de)	2011-03-15	Imidazopyridinone
DE502007001207D1 (de)	2009-09-10	Elektrosaugkopf
DK2159224T3 (da)	2012-08-20	Bromphenylsubstituerede thiazolyldihydropyrimidiner
ATE514696T1 (de)	2011-07-15	Diphenyl-dihydro-imidazopyridinone
DE112008003636A5 (de)	2010-10-21	Mehrzuggruppierer
DE602008002772D1 (de)	2010-11-11	Polyvinylpyrrolidonpulverzusammensetzungen
DE602008000749D1 (de)	2010-04-15	Buschschneider
DE602008000923D1 (de)	2010-05-20	Einzelwaferätzgerät
BRPI0814519A2 (pt)	2014-09-30	Organopolissiloxano
BRPI0811451A2 (pt)	2014-11-04	Exopolissacarídeo
BRPI0815547A2 (pt)	2015-02-10	Depsipeptídeos cícliocos
BRPI0812840A2 (pt)	2014-12-09	2-imidazolinas
DE602008001234D1 (de)	2010-06-24	Bandmaterialzuführvorrichtung
DE602008004695D1 (de)	2011-03-10	Katalysatorträgerwabe
AT505058A3 (de)	2008-12-15	Türschliesssystem
BRPI0812994A2 (pt)	2014-12-23	Microbiocidas
DE602008005950D1 (de)	2011-05-19	Münzvereinzeler
DE602008005589D1 (de)	2011-04-28	Rliganden
DE602008001674D1 (de)	2010-08-19	Wimpernwickler
DE112008001216A5 (de)	2010-02-04	Magnetronplasmaanlage
DE502008001694D1 (de)	2010-12-16	Mitfahrhubwagen
DE112008003094A5 (de)	2010-08-12	Geomatte
DE112008003196A5 (de)	2011-02-03	Handpipettiergerät