BRPI0810893A2 - Uso de inibidor de tnf-alfa a um anti-histamínico para tratar rinite alérgica e conjuntivite, e composição farmacêutica compreendendo os referidos compostos. - Google Patents
Uso de inibidor de tnf-alfa a um anti-histamínico para tratar rinite alérgica e conjuntivite, e composição farmacêutica compreendendo os referidos compostos.Info
- Publication number
- BRPI0810893A2 BRPI0810893A2 BRPI0810893-5A2A BRPI0810893A BRPI0810893A2 BR PI0810893 A2 BRPI0810893 A2 BR PI0810893A2 BR PI0810893 A BRPI0810893 A BR PI0810893A BR PI0810893 A2 BRPI0810893 A2 BR PI0810893A2
- Authority
- BR
- Brazil
- Prior art keywords
- antihistamine
- conjunctivitis
- tnf
- compounds
- pharmaceutical composition
- Prior art date
Links
- 206010010744 Conjunctivitis allergic Diseases 0.000 title 1
- 206010039085 Rhinitis allergic Diseases 0.000 title 1
- GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 title 1
- 208000002205 allergic conjunctivitis Diseases 0.000 title 1
- 201000010105 allergic rhinitis Diseases 0.000 title 1
- 230000001387 anti-histamine Effects 0.000 title 1
- 239000000739 antihistaminic agent Substances 0.000 title 1
- 208000024998 atopic conjunctivitis Diseases 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 229940046728 tumor necrosis factor alpha inhibitor Drugs 0.000 title 1
- 239000002452 tumor necrosis factor alpha inhibitor Substances 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/191—Tumor necrosis factors [TNF], e.g. lymphotoxin [LT], i.e. TNF-beta
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Pulmonology (AREA)
- Ophthalmology & Optometry (AREA)
- Mycology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US91117607P | 2007-04-11 | 2007-04-11 | |
| PCT/US2008/059885 WO2008127975A2 (en) | 2007-04-11 | 2008-04-10 | Use of an inhibitor of tnfa plus an antihistamine to treat allergic rhinitis and allergic conjunctivitis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0810893A2 true BRPI0810893A2 (pt) | 2014-10-29 |
Family
ID=39523827
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0810893-5A2A BRPI0810893A2 (pt) | 2007-04-11 | 2008-04-10 | Uso de inibidor de tnf-alfa a um anti-histamínico para tratar rinite alérgica e conjuntivite, e composição farmacêutica compreendendo os referidos compostos. |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20080254029A1 (pt) |
| EP (1) | EP2131834A2 (pt) |
| JP (1) | JP2010523695A (pt) |
| KR (1) | KR20100014565A (pt) |
| CN (1) | CN101641094A (pt) |
| AR (1) | AR066016A1 (pt) |
| AU (1) | AU2008240279A1 (pt) |
| BR (1) | BRPI0810893A2 (pt) |
| CA (1) | CA2682730A1 (pt) |
| CL (1) | CL2008001038A1 (pt) |
| MX (1) | MX2009010946A (pt) |
| RU (1) | RU2009141592A (pt) |
| TW (1) | TW200902025A (pt) |
| UY (1) | UY31017A1 (pt) |
| WO (1) | WO2008127975A2 (pt) |
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| US20090281075A1 (en) * | 2006-02-17 | 2009-11-12 | Pharmacopeia, Inc. | Isomeric purinones and 1h-imidazopyridinones as pkc-theta inhibitors |
| CL2007002866A1 (es) * | 2006-10-04 | 2008-07-04 | Pharmacopeia Inc | Compuestos derivados de 6-sustituidos-2-(bencimidazolil) purina y purinona; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto en el tratamiento de enfermedades autoinmunes, enfermedad inflamatoria, enfermedad mediada por m |
| US7915268B2 (en) * | 2006-10-04 | 2011-03-29 | Wyeth Llc | 8-substituted 2-(benzimidazolyl)purine derivatives for immunosuppression |
| US7902187B2 (en) * | 2006-10-04 | 2011-03-08 | Wyeth Llc | 6-substituted 2-(benzimidazolyl)purine and purinone derivatives for immunosuppression |
| US20080119496A1 (en) * | 2006-11-16 | 2008-05-22 | Pharmacopeia Drug Discovery, Inc. | 7-Substituted Purine Derivatives for Immunosuppression |
| US20090182035A1 (en) * | 2007-04-11 | 2009-07-16 | Alcon Research, Ltd. | Use of a combination of olopatadine and cilomilast to treat non-infectious rhinitis and allergic conjunctivitis |
| AU2008273804B2 (en) * | 2007-07-11 | 2014-07-10 | Pfizer Inc. | Pharmaceutical compositions and methods of treating dry eye disorders |
| US8569273B2 (en) | 2009-03-17 | 2013-10-29 | Aciex Therapeutics, Inc. | Ophthalmic formulations of cetirizine and methods of use |
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| US20060177430A1 (en) * | 2002-12-20 | 2006-08-10 | Chakshu Research Inc | Treatment of ocular disorders with ophthalmic formulations containing methylsulfonylmethane as a transport enhancer |
| JP2007524397A (ja) * | 2003-07-03 | 2007-08-30 | ザ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・ペンシルベニア | Sykキナーゼ発現の阻害 |
| US20050192261A1 (en) * | 2003-09-15 | 2005-09-01 | Jost-Price Edward R. | Methods and reagents for the treatment of immunoinflammatory disorders |
| WO2005049832A2 (en) * | 2003-11-14 | 2005-06-02 | Yale University | FcϜRIIA-SPECIFIC NUCLEIC ACID INTERFERENCE |
| MY141255A (en) * | 2003-12-11 | 2010-03-31 | Memory Pharm Corp | Phosphodiesterase 4 inhibitors, including n-substituted diarylamine analogs |
| US20050254212A1 (en) * | 2004-05-17 | 2005-11-17 | Eins Oe-Tech Co., Ltd. | Heat dissipation module for electronic device |
| MX2007000104A (es) * | 2004-07-06 | 2007-07-18 | Bioren Inc | Anticuerpos anti-tnf-? de gran afinidad y metodo. |
-
2008
- 2008-04-10 JP JP2010503203A patent/JP2010523695A/ja active Pending
- 2008-04-10 AU AU2008240279A patent/AU2008240279A1/en not_active Abandoned
- 2008-04-10 RU RU2009141592/15A patent/RU2009141592A/ru not_active Application Discontinuation
- 2008-04-10 MX MX2009010946A patent/MX2009010946A/es unknown
- 2008-04-10 BR BRPI0810893-5A2A patent/BRPI0810893A2/pt not_active Application Discontinuation
- 2008-04-10 EP EP08745485A patent/EP2131834A2/en not_active Withdrawn
- 2008-04-10 CA CA002682730A patent/CA2682730A1/en not_active Abandoned
- 2008-04-10 CN CN200880009226A patent/CN101641094A/zh active Pending
- 2008-04-10 KR KR1020097019961A patent/KR20100014565A/ko not_active Withdrawn
- 2008-04-10 AR ARP080101489A patent/AR066016A1/es unknown
- 2008-04-10 TW TW097112986A patent/TW200902025A/zh unknown
- 2008-04-10 UY UY31017A patent/UY31017A1/es not_active Application Discontinuation
- 2008-04-10 WO PCT/US2008/059885 patent/WO2008127975A2/en not_active Ceased
- 2008-04-10 US US12/100,715 patent/US20080254029A1/en not_active Abandoned
- 2008-04-11 CL CL2008001038A patent/CL2008001038A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2131834A2 (en) | 2009-12-16 |
| WO2008127975A2 (en) | 2008-10-23 |
| AU2008240279A1 (en) | 2008-10-23 |
| WO2008127975A3 (en) | 2009-07-30 |
| CN101641094A (zh) | 2010-02-03 |
| MX2009010946A (es) | 2009-10-29 |
| KR20100014565A (ko) | 2010-02-10 |
| RU2009141592A (ru) | 2011-05-20 |
| UY31017A1 (es) | 2008-07-03 |
| CL2008001038A1 (es) | 2009-01-16 |
| US20080254029A1 (en) | 2008-10-16 |
| TW200902025A (en) | 2009-01-16 |
| CA2682730A1 (en) | 2008-10-23 |
| AR066016A1 (es) | 2009-07-15 |
| JP2010523695A (ja) | 2010-07-15 |
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