BRPI0811589A2 - Composição farmacêutica e método para tratar câncer - Google Patents

Composição farmacêutica e método para tratar câncer

Info

Publication number
BRPI0811589A2
BRPI0811589A2 BRPI0811589-3A2A BRPI0811589A BRPI0811589A2 BR PI0811589 A2 BRPI0811589 A2 BR PI0811589A2 BR PI0811589 A BRPI0811589 A BR PI0811589A BR PI0811589 A2 BRPI0811589 A2 BR PI0811589A2
Authority
BR
Brazil
Prior art keywords
pharmaceutical composition
treating cancer
cancer
treating
pharmaceutical
Prior art date
Application number
BRPI0811589-3A2A
Other languages
English (en)
Inventor
Michel C Vellard
Paul A Fitzpatrick
Emil D Kakkis
Daniel J Wendt
Mubarack Muthalif
Sean M Bell
Augustus O Okhamafe
Original Assignee
Biomarin Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40363135&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0811589(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biomarin Pharm Inc filed Critical Biomarin Pharm Inc
Priority to BR122018072594A priority Critical patent/BR122018072594B8/pt
Publication of BRPI0811589A2 publication Critical patent/BRPI0811589A2/pt
Publication of BRPI0811589B1 publication Critical patent/BRPI0811589B1/pt
Publication of BRPI0811589B8 publication Critical patent/BRPI0811589B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/51—Lyases (4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Reproductive Health (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BRPI0811589A 2007-08-17 2008-08-15 composição farmacêutica, e, usos de uma composição farmacêutica BRPI0811589B8 (pt)

Priority Applications (1)

Application Number Priority Date Filing Date Title
BR122018072594A BR122018072594B8 (pt) 2007-08-17 2008-08-15 uso de uma composição farmacêutica

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6612507P 2007-08-17 2007-08-17
US61/066,125 2007-08-17
PCT/US2008/009765 WO2009025760A2 (en) 2007-08-17 2008-08-15 Compositions of prokaryotic phenylalanine ammonia-lyase and methods of treating cancer using compositions thereof

Publications (3)

Publication Number Publication Date
BRPI0811589A2 true BRPI0811589A2 (pt) 2014-10-29
BRPI0811589B1 BRPI0811589B1 (pt) 2020-05-12
BRPI0811589B8 BRPI0811589B8 (pt) 2021-05-25

Family

ID=40363135

Family Applications (2)

Application Number Title Priority Date Filing Date
BR122018072594A BR122018072594B8 (pt) 2007-08-17 2008-08-15 uso de uma composição farmacêutica
BRPI0811589A BRPI0811589B8 (pt) 2007-08-17 2008-08-15 composição farmacêutica, e, usos de uma composição farmacêutica

Family Applications Before (1)

Application Number Title Priority Date Filing Date
BR122018072594A BR122018072594B8 (pt) 2007-08-17 2008-08-15 uso de uma composição farmacêutica

Country Status (23)

Country Link
US (4) US7560263B2 (pt)
EP (1) EP2175875B1 (pt)
JP (1) JP5584120B2 (pt)
CN (1) CN101803492B (pt)
AR (2) AR067972A1 (pt)
AU (1) AU2008289549B2 (pt)
BR (2) BR122018072594B8 (pt)
CA (1) CA2687028C (pt)
CL (1) CL2008002390A1 (pt)
CY (1) CY1118222T1 (pt)
DK (1) DK2175875T3 (pt)
ES (1) ES2602618T3 (pt)
HR (1) HRP20161474T1 (pt)
HU (1) HUE029510T4 (pt)
LT (1) LT2175875T (pt)
MX (1) MX2009012261A (pt)
PE (1) PE20090605A1 (pt)
PL (1) PL2175875T3 (pt)
PT (1) PT2175875T (pt)
RU (2) RU2553343C2 (pt)
SI (1) SI2175875T1 (pt)
TW (1) TWI418787B (pt)
WO (1) WO2009025760A2 (pt)

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US8796206B2 (en) 2007-11-15 2014-08-05 Amgen Inc. Aqueous formulation of erythropoiesis stimulating protein stabilised by antioxidants for parenteral administration
WO2010014225A2 (en) * 2008-07-30 2010-02-04 Biomarin Pharmaceutical Inc. Assays for detection of phenylalanine ammonia-lyase and antibodies to phenylalanine ammonia-lyase
WO2011078667A2 (en) 2009-12-22 2011-06-30 Dsm Ip Assets B.V. Method of finding a biocatalyst having ammonia lyase activity
ES2690542T3 (es) 2010-02-04 2018-11-21 Biomarin Pharmaceutical Inc. Método para purificar variantes de fenilalanina amoníaco-liasa procariotas
US20120148559A1 (en) 2010-12-01 2012-06-14 Board Of Regents The University Of Texas System Compositions and method for deimmunization of proteins
AU2013295621A1 (en) * 2012-07-27 2015-03-12 University Of North Texas Genetically modified probiotic for the treatment of phenylketonuria (PKU) disease
NZ713396A (en) 2013-04-18 2020-06-26 Codexis Inc Engineered phenylalanine ammonia lyase polypeptides
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WO2015161019A1 (en) 2014-04-16 2015-10-22 Codexis, Inc. Engineered tyrosine ammonia lyase
CN106456723B (zh) 2014-04-29 2021-03-09 康达医药科技有限公司 采用精氨酸酶i调节免疫系统的方法和组合物
US10752923B2 (en) 2014-07-14 2020-08-25 Cysbio Aps Processes for the production of hydroxycinnamic acids using polypeptides having tyrosine ammonia lyase activity
LT3237621T (lt) 2014-12-22 2023-09-25 Codexis, Inc. Žmogaus alfa-galaktozidazės variantai
IL305149A (en) 2016-07-26 2023-10-01 Biomarin Pharm Inc Novel adeno-associated virus capsid proteins
IT201600086488A1 (it) * 2016-08-22 2018-02-22 St Microelectronics Srl Dispositivo a semiconduttore e corrispondente procedimento
MX2019009615A (es) 2017-02-13 2019-10-14 Codexis Inc Polipeptidos dise?ados de fenilalanina amonio liasa.
TW202016314A (zh) 2018-05-09 2020-05-01 美商拜奧馬林製藥公司 治療苯丙酮尿症之方法
TW202005978A (zh) 2018-05-14 2020-02-01 美商拜奧馬林製藥公司 新穎肝靶向腺相關病毒載體
US10900055B2 (en) 2018-06-12 2021-01-26 Codexis, Inc. Engineered tyrosine ammonia lyase
CA3122524A1 (en) 2018-12-14 2020-06-18 Codexis, Inc. Engineered tyrosine ammonia lyase
AU2019403323B2 (en) 2018-12-20 2026-02-26 Codexis, Inc. Human alpha-galactosidase variants
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CN114585391A (zh) * 2019-08-07 2022-06-03 乐天医药生技股份有限公司 西妥昔单抗-ir700偶联物组合物
EP4501403A3 (en) 2019-08-30 2025-05-14 Société des Produits Nestlé S.A. Engineered lipase variants
JP2023507575A (ja) 2019-12-20 2023-02-24 コデクシス， インコーポレイテッド 操作された酸性アルファ－グルコシダーゼバリアント
JP2023512683A (ja) 2020-02-04 2023-03-28 コデクシス， インコーポレイテッド 操作されたロイシンデカルボキシラーゼ
TW202144575A (zh) 2020-04-03 2021-12-01 美商拜奧馬林製藥公司 使用ａａｖ及治療調配物之苯酮尿症治療
CN116897205A (zh) 2020-08-28 2023-10-17 科德克希思公司 工程化淀粉酶变体
AU2021334371A1 (en) 2020-08-28 2023-03-09 Codexis, Inc. Engineered protease variants
EP4341394A4 (en) 2021-05-19 2025-04-09 BioMarin Pharmaceutical Inc. Compositions of prokaryotic phenylalanine ammonia lyase and methods for treating adolescent patients
CA3220735A1 (en) 2021-05-21 2022-11-24 Codexis, Inc. Engineered methionine gamma lyase variants
JP2024540358A (ja) 2021-11-01 2024-10-31 シンティス バイオ，インコーポレイティド 工学操作ロイシン脱炭酸酵素
CN115873837A (zh) * 2022-11-18 2023-03-31 安徽盈科生物科技有限公司 高表达的新型的苯丙氨酸解氨酶
CN118931888A (zh) * 2023-05-09 2024-11-12 重庆派金生物科技有限公司 苯丙氨酸裂解酶突变体及其偶联物或其药学上可接受的盐
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US20250161466A1 (en) 2023-11-17 2025-05-22 Biomarin Pharmaceutical Inc. Conjugates of phenylalanine ammonia-lyase and poegma and methods for their use

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Also Published As

Publication number Publication date
PL2175875T3 (pl) 2017-04-28
US7790433B2 (en) 2010-09-07
SI2175875T1 (sl) 2017-01-31
US7537923B2 (en) 2009-05-26
HUE029510T4 (en) 2017-05-29
PT2175875T (pt) 2016-11-21
ES2602618T3 (es) 2017-02-21
HUE029510T2 (hu) 2017-02-28
CA2687028C (en) 2016-02-16
JP2010536759A (ja) 2010-12-02
AR117389A2 (es) 2021-08-04
TW200911283A (en) 2009-03-16
BR122018072594B1 (pt) 2020-10-27
RU2553343C2 (ru) 2015-06-10
WO2009025760A3 (en) 2009-06-25
CN101803492B (zh) 2014-05-07
EP2175875B1 (en) 2016-10-05
BRPI0811589B8 (pt) 2021-05-25
CN101803492A (zh) 2010-08-11
BR122018072594B8 (pt) 2021-07-27
AU2008289549B2 (en) 2014-02-06
CY1118222T1 (el) 2017-06-28
US20090263369A1 (en) 2009-10-22
BRPI0811589B1 (pt) 2020-05-12
PE20090605A1 (es) 2009-05-16
HRP20161474T1 (hr) 2016-12-30
US7560263B2 (en) 2009-07-14
RU2009141987A (ru) 2011-05-20
AR067972A1 (es) 2009-10-28
AU2008289549A1 (en) 2009-02-26
US20100278802A1 (en) 2010-11-04
DK2175875T3 (en) 2016-11-21
WO2009025760A2 (en) 2009-02-26
TWI418787B (zh) 2013-12-11
EP2175875A2 (en) 2010-04-21
CL2008002390A1 (es) 2009-05-29
RU2012134838A (ru) 2014-03-20
JP5584120B2 (ja) 2014-09-03
MX2009012261A (es) 2010-03-15
US20090047265A1 (en) 2009-02-19
CA2687028A1 (en) 2009-02-26
LT2175875T (lt) 2016-12-12
US20090047268A1 (en) 2009-02-19

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