BRPI0812856A2 - Composições de vacina de emulsão que compreendem antígeno e adjuvante na fase aquosa. - Google Patents

Composições de vacina de emulsão que compreendem antígeno e adjuvante na fase aquosa.

Info

Publication number: BRPI0812856A2
Authority: BR; Brazil
Prior art keywords: adjuvant; antigen; vaccine compositions; water stage; emulsion vaccine
Prior art date: 2007-06-20

Application number

BRPI0812856-1A2A

Other languages

English (en)

Inventor

David Leon Lutz

Jeffrey Harold Rodenberg

Original Assignee

Wyeth Llc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-06-20

Filing date

2008-06-19

Publication date

2014-12-09

2008-06-19 Application filed by Wyeth Llc filed Critical Wyeth Llc

2014-12-09 Publication of BRPI0812856A2 publication Critical patent/BRPI0812856A2/pt

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/145—Orthomyxoviridae, e.g. influenza virus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16171—Demonstrated in vivo effect

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Immunology (AREA)
Epidemiology (AREA)
Virology (AREA)
Microbiology (AREA)
Mycology (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Pulmonology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Genetics & Genomics (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
General Engineering & Computer Science (AREA)
Biotechnology (AREA)
Biomedical Technology (AREA)
Biochemistry (AREA)
Dispersion Chemistry (AREA)
Molecular Biology (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicinal Preparation (AREA)

BRPI0812856-1A2A 2007-06-20 2008-06-19 Composições de vacina de emulsão que compreendem antígeno e adjuvante na fase aquosa. BRPI0812856A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US93657107P	2007-06-20	2007-06-20
PCT/US2008/067433 WO2008157659A1 (en)	2007-06-20	2008-06-19	Emulsion vaccine compositions comprising antigen and adjuvant in the aqueous phase

Publications (1)

Publication Number	Publication Date
BRPI0812856A2 true BRPI0812856A2 (pt)	2014-12-09

Family

ID=39720537

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0812856-1A2A BRPI0812856A2 (pt)	2007-06-20	2008-06-19	Composições de vacina de emulsão que compreendem antígeno e adjuvante na fase aquosa.

Country Status (26)

Country	Link
US (2)	US8980288B2 (pt)
EP (1)	EP2164510B1 (pt)
JP (2)	JP5457340B2 (pt)
KR (1)	KR101569218B1 (pt)
CN (2)	CN105148268A (pt)
AR (1)	AR067087A1 (pt)
AU (1)	AU2008265745B2 (pt)
BR (1)	BRPI0812856A2 (pt)
CA (1)	CA2692098C (pt)
CL (1)	CL2008001806A1 (pt)
CO (1)	CO6251273A2 (pt)
CY (1)	CY1114451T1 (pt)
DK (1)	DK2164510T3 (pt)
ES (1)	ES2429296T3 (pt)
HK (1)	HK1218717A1 (pt)
HR (1)	HRP20130939T1 (pt)
ME (1)	ME01527B (pt)
MX (1)	MX2009014070A (pt)
NZ (1)	NZ582132A (pt)
PL (1)	PL2164510T3 (pt)
PT (1)	PT2164510E (pt)
RS (1)	RS52947B (pt)
SI (1)	SI2164510T1 (pt)
TW (1)	TWI507214B (pt)
WO (1)	WO2008157659A1 (pt)
ZA (1)	ZA200909173B (pt)

Families Citing this family (23)

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CL2008001806A1 (es) *	2007-06-20	2008-09-05	Wyeth Corp	Composicion de vacuna en emulsion agua en aceite que comprende un antigeno y un adyuvante en la fase acuosa; y metodo de elaboracion.
ES2569907T3 (es)	2008-06-27	2016-05-13	Zoetis Services Llc	Composiciones adyuvantes novedosas
AU2010232180B2 (en) *	2009-03-31	2016-09-22	Japan As Represented By The Director-General Of National Institute Of Infectious Diseases	Method for prophylaxis of influenza using vaccine for intranasal administration
CN102741537B (zh)	2010-01-29	2016-01-06	唐纳森公司	用于空气滤清器的水分离器组件及发动机空气流入口结构
CN101829323A (zh) *	2010-04-28	2010-09-15	洛阳普莱柯生物工程有限公司	一种禽用油乳剂疫苗及其制备方法
WO2012139179A1 (pt)	2011-04-12	2012-10-18	Ouro Fino Participações E Empreendimentos S/A	Peptídeos com atividade antimicrobiana, composições medicamentosas para o tratamento e profilaxia de animais, composições para o tratamento e profilaxia de plantas, usos dos ditos peptídeos, e, usos do extrato de paenibacillus elgii ourofinensis
KR20200039025A (ko)	2013-09-19	2020-04-14	조에티스 서비시즈 엘엘씨	유성 아쥬반트
KR20160095124A (ko) *	2013-12-06	2016-08-10	어드밴스드 바이오뉴트리션 코포레이션	생물활성제의 경구 전달을 위한 조성물
MX391930B (es)	2015-01-16	2025-03-21	Zoetis Services Llc	Vacuna contra la fiebre aftosa.
GB201506948D0 (en) *	2015-04-23	2015-06-10	Croda Int Plc	Emulsions for injectable formulations
CN106177939B (zh) *	2015-06-01	2021-01-19	普莱柯生物工程股份有限公司	一种疫苗用佐剂及其应用
CN106344920B (zh) *	2015-07-16	2020-11-27	普莱柯生物工程股份有限公司	一种疫苗用佐剂及其应用
CN107281482B (zh) *	2016-04-05	2021-06-11	普莱柯生物工程股份有限公司	一种免疫佐剂组合物及其制备方法
CN112243373B (zh) *	2018-03-13	2023-09-22	胶囊技术私人有限公司	疫苗组合物
CN110404065B (zh) *	2018-04-27	2023-06-16	洛阳赛威生物科技有限公司	一种猪用佐剂组合物及其制备方法
US11813321B2 (en)	2018-07-13	2023-11-14	Biomune Company	Vaccines against avian reoviruses
AU2019311181A1 (en)	2018-07-27	2021-02-18	Research Development Foundation	Chimeric immunogenic polypeptides
US12246090B2 (en)	2018-10-16	2025-03-11	Intervet Inc.	Stable emulsions of bacterial antigens
PH12022550081A1 (en)	2019-07-12	2023-04-12	Res Found Dev	Ehrlichia vaccines and immunogenic compositions
CN114306585A (zh) *	2021-12-30	2022-04-12	广西壮族自治区水产科学研究院	一种鱼类高纯度抗原乳剂的制备方法
US12226468B2 (en)	2023-06-26	2025-02-18	Research Development Foundation	Immunoreactive peptides
WO2025018848A1 (ko) *	2023-07-19	2025-01-23	주식회사 유틸렉스	하프니아 알베이 유래 지질다당류 및 카보머를 포함하는 면역증강용 조성물
CN119656300A (zh) *	2024-12-17	2025-03-21	长江大学	一种猪繁殖与呼吸综合征灭活苗专用油佐剂及其制备方法和应用

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NZ221306A (en)	1986-08-15	1990-02-26	Commw Scient Ind Res Org	2-component immunoadjuvant comprising a mycobacterial free immunoadjuvant oil and a polycationic polyelectrolyte immunoadjuvant and vaccines thereof
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US5951988A (en) *	1993-03-30	1999-09-14	University Of Saskatchewan	Adjuvant formulation with enhanced immunogenic activity, and related compositions and methods
BE1008977A5 (fr)	1994-12-27	1996-10-01	Solvay	Adjuvants pour vaccins.
US5744137A (en)	1995-02-06	1998-04-28	The United States Of America As Represented By The Secretary Of The Agriculture	Oil emulsion vaccines prepared with animal, vegetable, and synthetic oils using a mixture of nonionic surfactants
PT1042001E (pt) *	1997-12-16	2002-09-30	Chiron Corp	Uso de microparticulas combinadas com emulsoes submicronicas oleo-em-agua
FR2775601B1 (fr) *	1998-03-03	2001-09-21	Merial Sas	Vaccins vivants recombines et adjuves
FR2776928B1 (fr)	1998-04-03	2000-06-23	Merial Sas	Vaccins adn adjuves
JP2003533989A (ja) *	2000-05-24	2003-11-18	メリアル	ブタ生殖・呼吸症候群ウィルス（ｐｒｒｓｖ）の組換えポックスウィルスワクチン
FR2810888B1 (fr) *	2000-06-29	2004-07-30	Merial Sas	Vaccin contre la fievre aphteuse
US6585978B1 (en) *	2000-09-09	2003-07-01	Akzo Nobel	EIA vaccine and diagnostic
US7018638B2 (en)	2000-12-19	2006-03-28	Wyeth	Mycoplasma hyopneumoniae bacterin vaccine
US6676958B2 (en)	2001-06-19	2004-01-13	Advanced Bioadjuvants, Llc	Adjuvant composition for mucosal and injection delivered vaccines
US20030129161A1 (en)	2001-09-17	2003-07-10	Hsien-Jue Chu	Interleukin-12 as a veterinary vaccine adjuvant
JP3812814B2 (ja) *	2001-10-19	2006-08-23	株式会社微生物化学研究所	動物用多価オイルアジュバントワクチン
US7862821B2 (en)	2006-06-01	2011-01-04	Merial Limited	Recombinant vaccine against bluetongue virus
CL2008001806A1 (es) *	2007-06-20	2008-09-05	Wyeth Corp	Composicion de vacuna en emulsion agua en aceite que comprende un antigeno y un adyuvante en la fase acuosa; y metodo de elaboracion.

2008
- 2008-06-18 CL CL200801806A patent/CL2008001806A1/es unknown
- 2008-06-19 CN CN201510450651.5A patent/CN105148268A/zh active Pending
- 2008-06-19 CA CA2692098A patent/CA2692098C/en not_active Expired - Fee Related
- 2008-06-19 HR HRP20130939AT patent/HRP20130939T1/hr unknown
- 2008-06-19 KR KR1020107001106A patent/KR101569218B1/ko not_active Expired - Fee Related
- 2008-06-19 MX MX2009014070A patent/MX2009014070A/es active IP Right Grant
- 2008-06-19 BR BRPI0812856-1A2A patent/BRPI0812856A2/pt not_active IP Right Cessation
- 2008-06-19 ME MEP-2013-101A patent/ME01527B/me unknown
- 2008-06-19 JP JP2010513396A patent/JP5457340B2/ja not_active Expired - Fee Related
- 2008-06-19 WO PCT/US2008/067433 patent/WO2008157659A1/en not_active Ceased
- 2008-06-19 US US12/142,160 patent/US8980288B2/en active Active
- 2008-06-19 SI SI200831038T patent/SI2164510T1/sl unknown
- 2008-06-19 RS RS20130408A patent/RS52947B/sr unknown
- 2008-06-19 AU AU2008265745A patent/AU2008265745B2/en not_active Ceased
- 2008-06-19 PL PL08771428T patent/PL2164510T3/pl unknown
- 2008-06-19 DK DK08771428.3T patent/DK2164510T3/da active
- 2008-06-19 EP EP08771428.3A patent/EP2164510B1/en active Active
- 2008-06-19 ES ES08771428T patent/ES2429296T3/es active Active
- 2008-06-19 CN CN200880024112A patent/CN101790378A/zh active Pending
- 2008-06-19 PT PT87714283T patent/PT2164510E/pt unknown
- 2008-06-19 NZ NZ582132A patent/NZ582132A/en not_active IP Right Cessation
- 2008-06-20 TW TW097123236A patent/TWI507214B/zh not_active IP Right Cessation
- 2008-06-20 AR ARP080102641A patent/AR067087A1/es not_active Application Discontinuation
2009
- 2009-12-17 CO CO09144676A patent/CO6251273A2/es not_active Application Discontinuation
- 2009-12-22 ZA ZA200909173A patent/ZA200909173B/xx unknown
2010
- 2010-11-09 HK HK16106725.1A patent/HK1218717A1/zh unknown
2013
- 2013-10-03 CY CY20131100855T patent/CY1114451T1/el unknown
2014
- 2014-01-09 JP JP2014002096A patent/JP5802285B2/ja not_active Expired - Fee Related
2015
- 2015-02-10 US US14/618,628 patent/US9545439B2/en active Active

Also Published As

Publication number	Publication date
CN101790378A (zh)	2010-07-28
PT2164510E (pt)	2013-10-07
SI2164510T1 (sl)	2013-11-29
ZA200909173B (en)	2010-08-25
AR067087A1 (es)	2009-09-30
CY1114451T1 (el)	2016-10-05
ES2429296T3 (es)	2013-11-14
HRP20130939T1 (hr)	2013-11-22
PL2164510T3 (pl)	2014-03-31
HK1218717A1 (zh)	2017-03-10
US20090017067A1 (en)	2009-01-15
US8980288B2 (en)	2015-03-17
JP5457340B2 (ja)	2014-04-02
JP5802285B2 (ja)	2015-10-28
WO2008157659A1 (en)	2008-12-24
EP2164510B1 (en)	2013-07-17
NZ582132A (en)	2012-04-27
JP2010530877A (ja)	2010-09-16
MX2009014070A (es)	2010-05-19
CA2692098C (en)	2016-06-14
EP2164510A1 (en)	2010-03-24
US20150297710A1 (en)	2015-10-22
KR20100022115A (ko)	2010-02-26
JP2014088423A (ja)	2014-05-15
CA2692098A1 (en)	2008-12-24
CN105148268A (zh)	2015-12-16
DK2164510T3 (da)	2013-09-23
TW200906448A (en)	2009-02-16
TWI507214B (zh)	2015-11-11
ME01527B (me)	2014-04-20
CL2008001806A1 (es)	2008-09-05
CO6251273A2 (es)	2011-02-21
AU2008265745A1 (en)	2008-12-24
AU2008265745B2 (en)	2013-05-30
US9545439B2 (en)	2017-01-17
KR101569218B1 (ko)	2015-11-13
RS52947B (sr)	2014-02-28

Legal Events

Date	Code	Title	Description
2016-03-08	B25A	Requested transfer of rights approved	Owner name: PAH W LLC (US)
2016-03-29	B25D	Requested change of name of applicant approved	Owner name: ZOETIS W LLC (US)
2017-05-16	B15K	Others concerning applications: alteration of classification	Ipc: A61K 39/39 (2006.01), A61K 39/145 (2006.01)
2017-07-04	B07A	Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
2018-04-17	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
2018-08-07	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

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