DK2164510T3 - Emulsionsvaccinesammensætninger omfattende antigen og adjuvant i den vandige fase - Google Patents

Emulsionsvaccinesammensætninger omfattende antigen og adjuvant i den vandige fase

Info

Publication number: DK2164510T3
Authority: DK; Denmark
Prior art keywords: adjuvant; aqueous phase; compositions including; vaccine compositions; including antigen
Prior art date: 2007-06-20

Application number

DK08771428.3T

Other languages

English (en)

Inventor

David Leon Lutz

Jeffrey Harold Rodenberg

Evan James Diehl

Mahesh Kumar

Original Assignee

Zoetis W Llc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-06-20

Filing date

2008-06-19

Publication date

2013-09-23

2008-06-19 Application filed by Zoetis W Llc filed Critical Zoetis W Llc

2013-09-23 Application granted granted Critical

2013-09-23 Publication of DK2164510T3 publication Critical patent/DK2164510T3/da

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/145—Orthomyxoviridae, e.g. influenza virus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16171—Demonstrated in vivo effect

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Immunology (AREA)
Epidemiology (AREA)
Virology (AREA)
Microbiology (AREA)
Mycology (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Pulmonology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Genetics & Genomics (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Dispersion Chemistry (AREA)
Biotechnology (AREA)
Biomedical Technology (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicinal Preparation (AREA)

DK08771428.3T 2007-06-20 2008-06-19 Emulsionsvaccinesammensætninger omfattende antigen og adjuvant i den vandige fase DK2164510T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US93657107P	2007-06-20	2007-06-20
PCT/US2008/067433 WO2008157659A1 (en)	2007-06-20	2008-06-19	Emulsion vaccine compositions comprising antigen and adjuvant in the aqueous phase

Publications (1)

Publication Number	Publication Date
DK2164510T3 true DK2164510T3 (da)	2013-09-23

Family

ID=39720537

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK08771428.3T DK2164510T3 (da)	2007-06-20	2008-06-19	Emulsionsvaccinesammensætninger omfattende antigen og adjuvant i den vandige fase

Country Status (26)

Country	Link
US (2)	US8980288B2 (da)
EP (1)	EP2164510B1 (da)
JP (2)	JP5457340B2 (da)
KR (1)	KR101569218B1 (da)
CN (2)	CN105148268A (da)
AR (1)	AR067087A1 (da)
AU (1)	AU2008265745B2 (da)
BR (1)	BRPI0812856A2 (da)
CA (1)	CA2692098C (da)
CL (1)	CL2008001806A1 (da)
CO (1)	CO6251273A2 (da)
CY (1)	CY1114451T1 (da)
DK (1)	DK2164510T3 (da)
ES (1)	ES2429296T3 (da)
HK (1)	HK1218717A1 (da)
HR (1)	HRP20130939T1 (da)
ME (1)	ME01527B (da)
MX (1)	MX2009014070A (da)
NZ (1)	NZ582132A (da)
PL (1)	PL2164510T3 (da)
PT (1)	PT2164510E (da)
RS (1)	RS52947B (da)
SI (1)	SI2164510T1 (da)
TW (1)	TWI507214B (da)
WO (1)	WO2008157659A1 (da)
ZA (1)	ZA200909173B (da)

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CL2008001806A1 (es) *	2007-06-20	2008-09-05	Wyeth Corp	Composicion de vacuna en emulsion agua en aceite que comprende un antigeno y un adyuvante en la fase acuosa; y metodo de elaboracion.
WO2009156960A2 (en)	2008-06-27	2009-12-30	Pfizer Inc.	Novel adjuvant compositions
AU2010232180B2 (en) *	2009-03-31	2016-09-22	Japan As Represented By The Director-General Of National Institute Of Infectious Diseases	Method for prophylaxis of influenza using vaccine for intranasal administration
BR112012018640B1 (pt)	2010-01-29	2020-12-15	Donaldson Company, Inc.	Montagens de separador de água de fluxo de ar de entrada e método de separar água de um fluxo de ar de entrada
CN101829323A (zh) *	2010-04-28	2010-09-15	洛阳普莱柯生物工程有限公司	一种禽用油乳剂疫苗及其制备方法
KR20140058423A (ko)	2011-04-12	2014-05-14	오루 피노 파르티시파코에스 에 엠프린디멘토스 에스/에이	항균 활성을 갖는 펩티드, 동물의 치료 및 예방을 위한 약물 조성물, 식물의 치료 및 예방을 위한 조성물, 상기 펩티드의 용도, 및 패니바실러스 엘기이 오우로피넨시스 추출물의 용도
UA121200C2 (uk) *	2013-09-19	2020-04-27	Зоетіс Сервісіз Ллс	Ад'ювант на основі олії
MX384321B (es) *	2013-12-06	2025-03-04	Intervet Int Bv	Composición para administración oral de agentes bioactivos.
EP4248992A3 (en)	2015-01-16	2023-12-27	Zoetis Services LLC	Foot-and-mouth disease vaccine
GB201506948D0 (en) *	2015-04-23	2015-06-10	Croda Int Plc	Emulsions for injectable formulations
CN106177939B (zh) *	2015-06-01	2021-01-19	普莱柯生物工程股份有限公司	一种疫苗用佐剂及其应用
CN106344920B (zh) *	2015-07-16	2020-11-27	普莱柯生物工程股份有限公司	一种疫苗用佐剂及其应用
CN107281482B (zh) *	2016-04-05	2021-06-11	普莱柯生物工程股份有限公司	一种免疫佐剂组合物及其制备方法
CN112243373B (zh) *	2018-03-13	2023-09-22	胶囊技术私人有限公司	疫苗组合物
CN110404065B (zh) *	2018-04-27	2023-06-16	洛阳赛威生物科技有限公司	一种猪用佐剂组合物及其制备方法
WO2020012428A1 (en) *	2018-07-13	2020-01-16	Biomune Company	New vaccines against avian reoviruses
CA3107319A1 (en)	2018-07-27	2020-01-30	Research Development Foundation	Chimeric immunogenic polypeptides
CA3114994A1 (en)	2018-10-16	2020-04-23	Intervet International B.V.	Stable emulsions of bacterial antigens
CA3146842A1 (en)	2019-07-12	2021-01-21	Research Development Foundation	Ehrlichia vaccines and immunogenic compositions
CN114306585A (zh) *	2021-12-30	2022-04-12	广西壮族自治区水产科学研究院	一种鱼类高纯度抗原乳剂的制备方法
EP4731640A1 (en)	2023-06-26	2026-04-29	Research Development Foundation	Immunoreactive peptides
TW202517283A (zh) *	2023-07-19	2025-05-01	南韓商優特力克斯有限公司	包含源自蜂房哈夫尼菌的脂多糖及卡波姆的免疫增強用組合物
CN119656300A (zh) *	2024-12-17	2025-03-21	长江大学	一种猪繁殖与呼吸综合征灭活苗专用油佐剂及其制备方法和应用

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2008
- 2008-06-18 CL CL200801806A patent/CL2008001806A1/es unknown
- 2008-06-19 WO PCT/US2008/067433 patent/WO2008157659A1/en not_active Ceased
- 2008-06-19 CN CN201510450651.5A patent/CN105148268A/zh active Pending
- 2008-06-19 PT PT87714283T patent/PT2164510E/pt unknown
- 2008-06-19 DK DK08771428.3T patent/DK2164510T3/da active
- 2008-06-19 US US12/142,160 patent/US8980288B2/en active Active
- 2008-06-19 PL PL08771428T patent/PL2164510T3/pl unknown
- 2008-06-19 CA CA2692098A patent/CA2692098C/en not_active Expired - Fee Related
- 2008-06-19 ME MEP-2013-101A patent/ME01527B/me unknown
- 2008-06-19 MX MX2009014070A patent/MX2009014070A/es active IP Right Grant
- 2008-06-19 BR BRPI0812856-1A2A patent/BRPI0812856A2/pt not_active IP Right Cessation
- 2008-06-19 AU AU2008265745A patent/AU2008265745B2/en not_active Ceased
- 2008-06-19 SI SI200831038T patent/SI2164510T1/sl unknown
- 2008-06-19 KR KR1020107001106A patent/KR101569218B1/ko not_active Expired - Fee Related
- 2008-06-19 ES ES08771428T patent/ES2429296T3/es active Active
- 2008-06-19 RS RS20130408A patent/RS52947B/sr unknown
- 2008-06-19 JP JP2010513396A patent/JP5457340B2/ja not_active Expired - Fee Related
- 2008-06-19 HR HRP20130939AT patent/HRP20130939T1/hr unknown
- 2008-06-19 CN CN200880024112A patent/CN101790378A/zh active Pending
- 2008-06-19 NZ NZ582132A patent/NZ582132A/en not_active IP Right Cessation
- 2008-06-19 EP EP08771428.3A patent/EP2164510B1/en active Active
- 2008-06-20 TW TW097123236A patent/TWI507214B/zh not_active IP Right Cessation
- 2008-06-20 AR ARP080102641A patent/AR067087A1/es not_active Application Discontinuation
2009
- 2009-12-17 CO CO09144676A patent/CO6251273A2/es not_active Application Discontinuation
- 2009-12-22 ZA ZA200909173A patent/ZA200909173B/xx unknown
2010
- 2010-11-09 HK HK16106725.1A patent/HK1218717A1/zh unknown
2013
- 2013-10-03 CY CY20131100855T patent/CY1114451T1/el unknown
2014
- 2014-01-09 JP JP2014002096A patent/JP5802285B2/ja not_active Expired - Fee Related
2015
- 2015-02-10 US US14/618,628 patent/US9545439B2/en active Active

Also Published As

Publication number	Publication date
JP2014088423A (ja)	2014-05-15
PL2164510T3 (pl)	2014-03-31
CA2692098A1 (en)	2008-12-24
BRPI0812856A2 (pt)	2014-12-09
HRP20130939T1 (hr)	2013-11-22
US20090017067A1 (en)	2009-01-15
AR067087A1 (es)	2009-09-30
HK1218717A1 (zh)	2017-03-10
JP5802285B2 (ja)	2015-10-28
US8980288B2 (en)	2015-03-17
ZA200909173B (en)	2010-08-25
KR20100022115A (ko)	2010-02-26
US9545439B2 (en)	2017-01-17
EP2164510B1 (en)	2013-07-17
CO6251273A2 (es)	2011-02-21
CL2008001806A1 (es)	2008-09-05
JP2010530877A (ja)	2010-09-16
TW200906448A (en)	2009-02-16
WO2008157659A1 (en)	2008-12-24
PT2164510E (pt)	2013-10-07
ME01527B (me)	2014-04-20
CY1114451T1 (el)	2016-10-05
AU2008265745B2 (en)	2013-05-30
CN105148268A (zh)	2015-12-16
MX2009014070A (es)	2010-05-19
KR101569218B1 (ko)	2015-11-13
NZ582132A (en)	2012-04-27
EP2164510A1 (en)	2010-03-24
AU2008265745A1 (en)	2008-12-24
ES2429296T3 (es)	2013-11-14
JP5457340B2 (ja)	2014-04-02
US20150297710A1 (en)	2015-10-22
TWI507214B (zh)	2015-11-11
CN101790378A (zh)	2010-07-28
RS52947B (sr)	2014-02-28
CA2692098C (en)	2016-06-14
SI2164510T1 (sl)	2013-11-29

Publication	Publication Date	Title
ZA200909173B (en)	2010-08-25	Emulsion vaccine compositions comprising antigen and adjuvant in the aqueous phase
HUS2200002I1 (hu)	2022-12-28	Immunogén készítmény
EP1917040A4 (en)	2012-12-12	POLYVALENT VACCINE
ATE520415T1 (de)	2011-09-15	Pneumokokken-polysaccharid-konjugat-vakzine
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