BRPI0813331A2 - Derivados de piperidina/piperazina - Google Patents
Derivados de piperidina/piperazinaInfo
- Publication number
- BRPI0813331A2 BRPI0813331A2 BRPI0813331-0A2A BRPI0813331A BRPI0813331A2 BR PI0813331 A2 BRPI0813331 A2 BR PI0813331A2 BR PI0813331 A BRPI0813331 A BR PI0813331A BR PI0813331 A2 BRPI0813331 A2 BR PI0813331A2
- Authority
- BR
- Brazil
- Prior art keywords
- piperidine
- piperazine derivatives
- piperazine
- derivatives
- Prior art date
Links
- NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical compound C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 title 2
- GLUUGHFHXGJENI-UHFFFAOYSA-N Piperazine Chemical class C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 title 1
- 229940066771 systemic antihistamines piperazine derivative Drugs 0.000 title 1
Classifications
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- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/205—Radicals derived from carbonic acid
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- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/04—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/58—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07109868 | 2007-06-08 | ||
| EP07115805 | 2007-09-06 | ||
| PCT/EP2008/057060 WO2008148868A1 (en) | 2007-06-08 | 2008-06-06 | Piperidine/piperazine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0813331A2 true BRPI0813331A2 (pt) | 2014-12-23 |
Family
ID=39865125
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0813331-0A2A BRPI0813331A2 (pt) | 2007-06-08 | 2008-06-06 | Derivados de piperidina/piperazina |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US8981094B2 (pt) |
| EP (1) | EP2152270B1 (pt) |
| JP (1) | JP5385263B2 (pt) |
| CN (1) | CN101678019B (pt) |
| AR (1) | AR066911A1 (pt) |
| AU (1) | AU2008258487B2 (pt) |
| BR (1) | BRPI0813331A2 (pt) |
| CA (1) | CA2687754C (pt) |
| CL (1) | CL2008001671A1 (pt) |
| ES (1) | ES2536406T3 (pt) |
| MX (1) | MX2009013335A (pt) |
| PA (1) | PA8783601A1 (pt) |
| PE (1) | PE20090362A1 (pt) |
| RU (1) | RU2470017C2 (pt) |
| TW (1) | TWI426070B (pt) |
| WO (1) | WO2008148868A1 (pt) |
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| USRE46117E1 (en) | 1999-12-22 | 2016-08-23 | Teva Pharmaceuticals International Gmbh | Modulators of dopamine neurotransmission |
| BRPI0519058A2 (pt) | 2004-12-14 | 2008-12-23 | Astrazeneca Ab | composto ou um sal prà-droga farmaceuticamente aceitÁvel do mesmo, mÉtodos para produzir uma inibiÇço da atividade de dgat1 e para tratar diabete melito e/ou obesidade em um animal de sangue quente, uso de um composto, composiÇço farmacÊutica, e, processo para preparar um composto |
| WO2007071966A1 (en) | 2005-12-22 | 2007-06-28 | Astrazeneca Ab | Pyrimido- [4, 5-b] -oxazines for use as dgat inhibitors |
| EP2418202B1 (en) | 2006-03-31 | 2014-01-29 | Novartis AG | (4-[4-[5-(substituted amino)-pyridin-2-yl]phenyl]-cyclohexyl)-acetic acid derivatives as DGAT inhibitors |
| MX2008015228A (es) | 2006-05-30 | 2008-12-12 | Astrazeneca Ab | Acido 5-fenilamino-1,3,4-oxadiazol-2-ilcarbonilamino-4-fenoxi-cicl ohexanocarboxilico sustituido como inhibidor de diacilglicerol aciltransferasa de acetil coenzima a. |
| JO2972B1 (en) | 2007-06-08 | 2016-03-15 | جانسين فارماسوتيكا ان. في | Piperidine / piperazine derivatives |
| EP2152271B1 (en) | 2007-06-08 | 2015-10-21 | Janssen Pharmaceutica, N.V. | Piperidine/piperazine derivatives |
| ES2536406T3 (es) | 2007-06-08 | 2015-05-25 | Janssen Pharmaceutica, N.V. | Derivados de piperidina/piperazina |
| JP5464709B2 (ja) | 2007-06-08 | 2014-04-09 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | ピペリジン/ピペラジン誘導体 |
| AR066169A1 (es) | 2007-09-28 | 2009-07-29 | Novartis Ag | Derivados de benzo-imidazoles, utiles para trastornos asociados con la actividad de dgat |
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| US9012159B2 (en) | 2009-02-04 | 2015-04-21 | Janssen Research & Development, Llc | Cell based screening assays for the triglyceride synthesis pathway |
| US9452980B2 (en) * | 2009-12-22 | 2016-09-27 | Hoffmann-La Roche Inc. | Substituted benzamides |
| SG11201608303QA (en) | 2014-04-04 | 2016-11-29 | Del Mar Pharmaceuticals | Use of dianhydrogalactitol and analogs or derivatives thereof to treat non-small-cell carcinoma of the lung and ovarian cancer |
| WO2016036638A1 (en) * | 2014-09-05 | 2016-03-10 | Merck Sharp & Dohme Corp. | Isoquinoline derivatives useful as inhibitors of diacylglyceride o-acyltransferase 2 |
| US10750742B2 (en) | 2015-12-22 | 2020-08-25 | Syngenta Participations Ag | Pesticidally active pyrazole derivatives |
| CN108713019B (zh) | 2016-03-17 | 2021-06-15 | 豪夫迈·罗氏有限公司 | 具有作为taar的激动剂的活性的5-乙基-4-甲基-吡唑-3-甲酰胺衍生物 |
| CN108250185B (zh) * | 2018-01-24 | 2020-08-21 | 浙江工业大学 | 6-(2-(邻甲苯氨基)乙酰氨基)喹唑啉类化合物及制备和应用 |
| CN109438252B (zh) * | 2018-12-27 | 2021-12-14 | 安徽工业大学科技园有限公司 | 一种三(2-氨基乙基)胺的合成工艺 |
| CN109516919B (zh) * | 2018-12-27 | 2021-12-14 | 安徽工业大学科技园有限公司 | 一种三(2-氨基乙基)胺的制备方法 |
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| ES2536406T3 (es) | 2007-06-08 | 2015-05-25 | Janssen Pharmaceutica, N.V. | Derivados de piperidina/piperazina |
| JO2972B1 (en) | 2007-06-08 | 2016-03-15 | جانسين فارماسوتيكا ان. في | Piperidine / piperazine derivatives |
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-
2008
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- 2008-06-06 PA PA20088783601A patent/PA8783601A1/es unknown
- 2008-06-06 AU AU2008258487A patent/AU2008258487B2/en not_active Ceased
- 2008-06-06 CL CL2008001671A patent/CL2008001671A1/es unknown
- 2008-06-06 AR ARP080102427A patent/AR066911A1/es unknown
- 2008-06-06 TW TW097121019A patent/TWI426070B/zh not_active IP Right Cessation
- 2008-06-06 RU RU2009148320/04A patent/RU2470017C2/ru active
- 2008-06-06 US US12/663,013 patent/US8981094B2/en active Active
- 2008-06-06 PE PE2008000972A patent/PE20090362A1/es not_active Application Discontinuation
- 2008-06-06 CA CA2687754A patent/CA2687754C/en active Active
- 2008-06-06 BR BRPI0813331-0A2A patent/BRPI0813331A2/pt not_active Application Discontinuation
- 2008-06-06 MX MX2009013335A patent/MX2009013335A/es active IP Right Grant
- 2008-06-06 CN CN200880019198.0A patent/CN101678019B/zh active Active
- 2008-06-06 JP JP2010510816A patent/JP5385263B2/ja active Active
- 2008-06-06 EP EP08760634.9A patent/EP2152270B1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CL2008001671A1 (es) | 2009-07-17 |
| AU2008258487B2 (en) | 2012-11-15 |
| CA2687754C (en) | 2015-12-08 |
| CN101678019B (zh) | 2016-03-30 |
| JP2010529089A (ja) | 2010-08-26 |
| ES2536406T3 (es) | 2015-05-25 |
| US20100190789A1 (en) | 2010-07-29 |
| JP5385263B2 (ja) | 2014-01-08 |
| US8981094B2 (en) | 2015-03-17 |
| RU2470017C2 (ru) | 2012-12-20 |
| CN101678019A (zh) | 2010-03-24 |
| WO2008148868A1 (en) | 2008-12-11 |
| PE20090362A1 (es) | 2009-04-04 |
| EP2152270B1 (en) | 2015-03-04 |
| EP2152270A1 (en) | 2010-02-17 |
| RU2009148320A (ru) | 2011-07-20 |
| AR066911A1 (es) | 2009-09-23 |
| TW200911771A (en) | 2009-03-16 |
| CA2687754A1 (en) | 2008-12-11 |
| MX2009013335A (es) | 2010-01-20 |
| TWI426070B (zh) | 2014-02-11 |
| AU2008258487A1 (en) | 2008-12-11 |
| PA8783601A1 (es) | 2009-01-23 |
| WO2008148868A8 (en) | 2009-03-05 |
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Legal Events
| Date | Code | Title | Description |
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| B07D | Technical examination (opinion) related to article 229 of industrial property law | ||
| B06F | Objections, documents and/or translations needed after an examination request according art. 34 industrial property law | ||
| B07E | Notice of approval relating to section 229 industrial property law | ||
| B07A | Technical examination (opinion): publication of technical examination (opinion) | ||
| B09B | Decision: refusal | ||
| B09B | Decision: refusal |
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