BRPI0814126A2 - Processo para a preparação de drospirenona - Google Patents

Processo para a preparação de drospirenona

Info

Publication number
BRPI0814126A2
BRPI0814126A2 BRPI0814126-6A2A BRPI0814126A BRPI0814126A2 BR PI0814126 A2 BRPI0814126 A2 BR PI0814126A2 BR PI0814126 A BRPI0814126 A BR PI0814126A BR PI0814126 A2 BRPI0814126 A2 BR PI0814126A2
Authority
BR
Brazil
Prior art keywords
drospyrenone
preparation process
preparation
drospirenone
substituent
Prior art date
Application number
BRPI0814126-6A2A
Other languages
English (en)
Inventor
Erika Andriolo
Mauro Montorsi
Stefano Rancan
Edoardo Mariani
Marco Bandini
Michele Contento
Achille Umani-Ronchi
Original Assignee
Newchem S P A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Newchem S P A filed Critical Newchem S P A
Publication of BRPI0814126A2 publication Critical patent/BRPI0814126A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • C07J53/004—3 membered carbocyclic rings
    • C07J53/008—3 membered carbocyclic rings in position 15/16

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
BRPI0814126-6A2A 2007-07-26 2008-07-21 Processo para a preparação de drospirenona BRPI0814126A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07014742A EP2019114B1 (en) 2007-07-26 2007-07-26 Process for the preparation of Drospirenone
PCT/EP2008/005949 WO2009012955A2 (en) 2007-07-26 2008-07-21 Process for the preparation of drospirenone

Publications (1)

Publication Number Publication Date
BRPI0814126A2 true BRPI0814126A2 (pt) 2015-02-03

Family

ID=38705123

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0814126-6A2A BRPI0814126A2 (pt) 2007-07-26 2008-07-21 Processo para a preparação de drospirenona

Country Status (14)

Country Link
US (1) US8383809B2 (pt)
EP (1) EP2019114B1 (pt)
AT (1) ATE491717T1 (pt)
BR (1) BRPI0814126A2 (pt)
CY (1) CY1111690T1 (pt)
DE (1) DE602007011250D1 (pt)
DK (1) DK2019114T3 (pt)
ES (1) ES2355586T3 (pt)
HR (1) HRP20110168T1 (pt)
PL (1) PL2019114T3 (pt)
PT (1) PT2019114E (pt)
RS (1) RS51892B (pt)
SI (1) SI2019114T1 (pt)
WO (1) WO2009012955A2 (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8334375B2 (en) 2009-04-10 2012-12-18 Evestra, Inc. Methods for the preparation of drospirenone
DE102009031909B4 (de) 2009-07-01 2017-02-09 Heyl Chemisch-Pharmazeutische Fabrik Gmbh & Co. Kg Verfahren zur Herstellung von Drospirenon aus Prasteron
DE102009031907B4 (de) 2009-07-01 2017-02-09 Heyl Chemisch-Pharmazeutische Fabrik Gmbh & Co. Kg Verfahren zur Herstellung von Drospirenon aus Androstendion
DE102009031908B4 (de) 2009-07-01 2017-02-09 Heyl Chemisch-Pharmazeutische Fabrik Gmbh & Co. Kg Verfahren zur Herstellung von Drospirenon aus 15-Hydroxyandrostendion
WO2011000535A2 (de) * 2009-07-01 2011-01-06 Heyl Chemisch-Pharmazeutische Fabrik Gmbh & Co. K Verfahren zur herstellung von drospirenon
DE102009038972A1 (de) 2009-08-23 2011-06-30 Heyl Chemisch-pharmazeutische Fabrik GmbH & Co. KG, 14167 Verfahren zur Herstellung von Drospirenon aus 6,7,15,16-Dimethylenandrost-4-en-3,17-dion
DE102010006818A1 (de) 2010-01-31 2011-08-04 Heyl Chemisch-pharmazeutische Fabrik GmbH & Co. KG, 14167 Verfahren zur Herstellung von Drospirenon aus 6ß, 7ß, 15ß, 16ß-Dimethylenandrost-4-en-3,17-dion
EP2415778B1 (en) 2010-08-03 2013-05-15 Newchem S.p.A. Methods for the preparation of Drospirenone and intermediates thereof
CN102887934B (zh) * 2012-09-20 2015-05-27 杭州福斯特药业有限公司 一种屈螺酮的制备方法
PT2984100T (pt) * 2013-04-12 2017-07-14 Ind Chimica Srl Processo para a preparação de drospirenona
CN114437169B (zh) * 2022-01-25 2023-04-07 台州仙琚药业有限公司 一种屈螺酮关键中间体溴代物的合成方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3042136A1 (de) * 1980-11-03 1982-06-09 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur herstellung von 3 (beta), 7 (beta) -dihydroxy- (delta) (pfeil hoch)5(pfeil hoch) -steroiden
ITMI20040367A1 (it) * 2004-03-01 2004-06-01 Ind Chimica Srl Processo per la preparazione di drospirenone
HUP0402465A2 (en) * 2004-11-30 2006-07-28 Richter Gedeon Vegyeszet Industrial process for preparing 17-hydroxy-6-betha, 7-betha, 15-betha, 16-betha-bis-methylene-3-oxo-17-alpha-pregn-4-ene-21-carboxylic acid gamma lacton and the main intermediates of the process
ITMI20042338A1 (it) * 2004-12-06 2005-03-06 Ind Chimica Srl Processo per la preparazione di drospirenone

Also Published As

Publication number Publication date
US8383809B2 (en) 2013-02-26
US20100222571A1 (en) 2010-09-02
CY1111690T1 (el) 2015-10-07
HRP20110168T1 (hr) 2011-04-30
PL2019114T3 (pl) 2011-05-31
SI2019114T1 (sl) 2011-04-29
ES2355586T3 (es) 2011-03-29
PT2019114E (pt) 2011-02-07
DE602007011250D1 (de) 2011-01-27
DK2019114T3 (da) 2011-02-14
WO2009012955A3 (en) 2009-04-02
EP2019114A1 (en) 2009-01-28
WO2009012955A2 (en) 2009-01-29
ATE491717T1 (de) 2011-01-15
RS51892B (sr) 2012-02-29
EP2019114B1 (en) 2010-12-15

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2471 DE 15-05-2018 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.